Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name KHSRPP1
Plot displaying the genomic locations of a retrocopy (in chr9) and its respective parental gene (in chr19). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr9:21695173-21700073  UCSC
Coordinates (T2T) chr9:21709375-21714273  UCSC
Coordinates (hg19) chr9:21695172-21700072  UCSC
Strand +
Parental Sequence NM_003685.3
Parental seq. overlap 2006 bp
Parental seq. overlap (%) 57.4%
Genomic Region Intergenic
Retrocopy Summary KHSRPP1, located on chr9:21695173-21700073, is a retrocopy of the parental gene KHSRP. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name KHSRP
Full Name KH-type splicing regulatory protein
Also known as FBP2|FUBP2|KSRP|p75
Coordinate chr19:6413102-6424811
Strand -
Gene summary The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997 [PubMed 9136930]; Gherzi et al., 2004 [PubMed 15175153]).[supplied by OMIM, Apr 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes KHSRPP1
Bonobo Pan paniscus KHSRPP2
Gorilla Gorilla gorilla KHSRPP1
Orangutan Pongo abelii KHSRPP1
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>KHSRPP1
AAGATCGCAGCCAAAATTGTAGGTGATGCTGCAACGACAGTGAATAACAGCACTCCAGATTTTGGTCTAGGGGGCCATAAGAGACAGTTGGAAGATGGAGATCAACCGGAGAGCAAGAAGCTGGCTTCCCAGGGAGACTCAATCAGTTCTCAACTTGGACCCATCCATCGTCCCCCAAGGACTTCAATGACAGAAGAGTGCAGGGTCCCAGACGGTGTGGTGGGCCTGATCTTTGGCAGAGGGCGCGAACAAATTGACAAAATCTAACAGGATTCAGCCTGCAAAGTATAGATTACTCCAGGCAGCAGTGGCCTACCCAAGCACAGTGTGTCCTTGACAAGAGCCCCAGAATCTCTCCAGAAAGCGAAGATGATGCTGGATGACATTGTGTCTCGGGGTCATGGGGGGCCCCCAGGACAGTTCCACGACACCGCCAAAGGGGGCCAGAATGGCACTGTACAGGACATGATCCCTGCGGGCAACGCCGGCCTGGTCATCGCCAAGGGCGGGGAGACCATGAAGCAGCTGCAGGAATACGCTGGAGTGAAGATGATCTTAATTCAAGATGGTTCTCAGAACACGAATGTGGACAACCCTCTCCGGATCCCTGGGGATCCTTACAAAGTGCAGCAAGCCTGCCAGATGGTGATGGACATCCTCCGGGAACGTGACCAAGGCGGCTTTGGGGACTGGAATGATTACGGATCTCGGACTGGCGGGGACATTGATGTGCCGGTGCCCAGGCATTCTGTCGGCGTGGTCATTGGCCTGAGAGGAGAGATGATCAAGAAGATCCAGAATGACGCTGGCGTGCCGATACAGTTCAAGCAAGATGATGGGACAGGGCCCGAGAAGATTGCTCATATAATGGGGTCCCCAGACAGGTGCGAGCACGCAGCCCGGATCATCAACGACCTCCTCCAGAGCCTCAGGAGTGGTCCCCCAGGCCCTCCAAGGGGTCCAGGCATGCCCCCGGGGAGGCCGAGGAAGAGGCCAAGGCAACTGGCGGCCCCCTGGCGGGGAGATGACCTTCTCCATCCCCACTCACAAGCGCCGGCTGGTCATCGGCCGAGGTGGCCAGAACGTGAAAGTCATAAACCAGCAGACTGTAGCCTTCGTAGAGATCTCCTGGCAGCTACCATCCAGTGGGGATCCCAACTTCAAGTCGTTCATCATCCAGGGTTCGCCCCAGCAGATCCAACACGCCGAGCAGCTTATCGAGGGGGCCCTTCAACCAGGGGCCACCTGGGCTCCCCCGCGTGCCTGGGGGCTCCCTCCTTACCAGGGCTGGGGCAATACCTACCCACAGTGGCAACCGCCTGCTCCTCACGATCCAAGCAAAGCAGCTGCGTCTACCGCGGACGCCAACGCCACATGGGCCGCCTACTACTCACATTACTACCAGCAGTCCCCGCCCCGTCGTCGGCCCCGCGCAGGTCCCCGGGGCTTCACCCGCTCAAGGTGAGCCCCCTCAGTCCCCGCCCACCGGCCAGTCGGACTACACTAAGGCCTGGGAAGAGTATTACAAAAAGATCGGCCCAGCAGCCCCAGCAGCCGGAAGCGCCCGGCAGCAGGACTACACGAAGGCCTGGGAGGAGCACTTCAAGAAGCAGGCGCCAAGTGGCCACCGGAGGGAGTCCAGGAACTCCCCCAGGCTGCCAGCCAGACTACAATGCAGTCTGGGGAGAATATTACAGACAGCAAGCCGCTTACTACGGACAGATCCCAGGTCCCGGCAGCCATGCATCAGGGACAGCAGCAGGCTCAATGAATGGAATGAATGTGAACTTCTTCATCTGTGAAAAATCGGGGGCTTCGGTTTTGTTTGGCGAGAGAGCGATGGCTGCCGTGAGGAGTATAGGGGAGCCCTTGCGGCAAGCTTGGGGGCTCAGGGACTTGGGAGCGTGCCGGGCCCTCACTCTCTCGCCCGTTCTGAGTCTCACATGCTTTTTCTCATGCTTTTTCTTTCAAAATTGGGATCCTTCAGGTTGAGCCAGCCAGAGAAGATAGCGAGGTGTAAATCTCTCCTTATTAAGTTATATATCTATATATAAAAAATATTTTTAAAAGGTAAATCATTTGTCTCATGACCTAGAATGAAACTAGCACAATAATTACAAATAATTTTGTTTGTCTATATACAAAATTTTAGATTGGTGCCATTTTATGAACAATACTGCACTTTTATAGTTATTTTGTGCAATTTTATAGTAATAGATATTTCTAGGTTCTCTGGTGTTCTTGTACGTGTTGATTTCTTGTTCTACAAACTACGTATTTGTAAAAGTGGGGTAGAGATTTTAATTTGTATGTATATATAAAAGTCTCTATTCTCCACCCCTCGGCATTCCTGAACCTGCCTCTCTGAGGATAAAGCAATTCATTTTCTCCCACCCTTAGCCCACTTCTTGCTTTTAAAATAAACTTCT
>NM_003685.3
AGAGTGCTCCGCGGCCGTGTGGAGCGAGGCCTTGTTCCCGCGTTGAgccgccgccgccgccgccgcctcctcagcttcagcctccgcgccaggcccggccccgccgcgccATGTCGGACTACAGCACGGGAGGACCCCCGCCCGGGCCGCCGCCGCCCGCCGGCGGGGGCGGGGGAGCCGGAGGCGCCGGGGGAGGCCCTCCGCCGGGCCCGCCAGGCGCGGGGGACCGGGGCGGCGGCGGTCCCGGCGGCGGCGGCCCGGGCGGGGGGTCGGCCGGGGGCCCCTCTCAGCCACCCGGCGGAGGCGGCCCGGGAATCCGCAAGGACGCTTTCGCCGACGCCGTGCAGCGGGCCCGCCAGATTGCAGCCAAAATTGGAGGCGATGCTGCCACGACAGTGAATAACAGCACTCCTGATTTTGGTTTTGGGGGCCAAAAGAGACAGTTGGAAGATGGAGATCAACCGGAGAGCAAGAAGCTGGCTTCCCAGGGAGACTCAATCAGTTCTCAACTTGGACCCATCCATCCTCCCCCAAGGACTTCAATGACAGAAGAGTACAGGGTCCCAGACGGCATGGTGGGCCTGATCATTGGCAGAGGAGGTGAACAAATTAACAAAATCCAACAGGATTCAGGCTGCAAAGTACAGATTTCTCCAGACAGCGGTGGCCTACCCGAGCGCAGTGTGTCCTTGACAGGAGCCCCAGAATCTGTCCAGAAAGCCAAGATGATGCTGGATGACATTGTGTCTCGGGGTCGTGGGGGCCCCCCAGGACAGTTCCACGACAACGCCAACGGGGGCCAGAACGGCACCGTGCAGGAGATCATGATCCCCGCGGGCAAGGCCGGCCTGGTCATTGGCAAGGGCGGGGAGACCATTAAGCAGCTGCAGGAACGCGCTGGAGTGAAGATGATCTTAATTCAGGACGGATCTCAGAATACGAATGTGGACAAACCTCTCCGCATCATTGGGGATCCTTACAAAGTGCAGCAAGCCTGTGAGATGGTGATGGACATCCTCCGGGAACGTGACCAAGGCGGCTTTGGGGACCGGAATGAGTACGGATCTCGGATTGGCGGAGGCATCGATGTGCCAGTGCCCAGGCATTCTGTTGGCGTGGTCATTGGCCGGAGTGGAGAGATGATCAAGAAGATCCAGAATGATGCTGGCGTGCGGATACAGTTCAAGCAAGATGACGGGACAGGGCCCGAGAAGATTGCTCATATAATGGGGCCCCCAGACAGGTGCGAGCACGCAGCCCGGATCATCAACGACCTCCTCCAGAGCCTCAGGAGTGGTCCCCCAGGTCCTCCAGGGGGTCCAGGCATGCCCCCGGGGGGCCGAGGCCGAGGAAGAGGCCAAGGCAATTGGGGTCCCCCTGGCGGGGAGATGACCTTCTCCATCCCCACTCACAAGTGTGGGCTGGTCATCGGCCGAGGTGGCGAGAATGTGAAAGCCATAAACCAGCAGACGGGAGCCTTCGTAGAGATCTCCCGGCAGCTGCCACCCAACGGGGACCCCAACTTCAAGTTGTTCATCATCCGGGGTTCACCCCAGCAGATTGACCACGCCAAGCAGCTTATCGAGGAAAAGATCGAGGGTCCTCTCTGCCCAGTTGGACCAGGCCCAGGTGGCCCAGGCCCTGCTGGCCCAATGGGGCCCTTCAATCCTGGGCCCTTCAACCAGGGGCCACCCGGGGCTCCCCCACATGCCGGGGGGCCCCCTCCTCACCAGTACCCACCCCAGGGCTGGGGCAATACCTACCCCCAGTGGCAGCCGCCTGCTCCTCATGACCCAAGCAAAGCAGCTGCAGCGGCCGCGGACCCCAACGCCGCGTGGGCCGCCTACTACTCACACTACTACCAGCAGCCcccgggccccgtccccggccccgcaccggcccctgcGGCCCCACCGGCTCAGGGTGAGCCCCCTCAGCCCCCACCCACCGGCCAGTCGGACTACACTAAGGCCTGGGAAGAGTATTACAAAAAGATCGGCCAGCAGCCCCAGCAGCCCGGAGCACCCCCACAGCAGGACTACACGAAGGCTTGGGAGGAGTACTACAAGAAGCAAGCGCAAGTGGCCACCGGAGGGGGTCCAGGAGCTCCCCCAGGCTCCCAGCCAGACTACAGTGCCGCCTGGGCGGAATATTACAGACAGCAGGCCGCTTACTACGGACAGACCCCAGGTCCTGGCGGCCCCCAGCCGCCGCCCACGCAGCAGGGACAGCAGCAGGCTCAATGAATCGAATGAATGTGAACTTCTTCATCTGTGAAAAATCTTTTTTTTTTCCATTTTGTTCTGTTTGGGGGCTTCTGTTTTGTTTGGCGAGAGAGCGATGGCTGCCGTGGGGAGTACTGGGGAGCCCTCGCGGCAAGCAGGGTGGGGGGGACTTGGGGGCATGCCGGGCCCTCACTCTCTCGCCTGTTCTGTGTCTCACATGCTTTTTCTTTCAAAATTGGGATCCTTCCATGTTGAGCCAGCCAGAGAAGATAGCGAGATCTAAATCTCTGCCaaaaaaaaaaaaaaacttaaaaattaaaaacacaaaGAGCAAAGCAGAACTTATAAAATTATATATATATATATTAAAAAGTCTCTATTCTTCACCCCCCAGCCTTCCTGAACCTGCCTCTCTGAGGATAAAGCAATTCATTTTCTCCCACCCTCGGCCCTCTTGTTTTTAAAATAAACTTTTAAAAAGGAAAAAAAAAAGTCACTCTTGCTATTTCTTTTTTTTAGTTAGAGGTGGAACATTCCTTGGACCAGGTGTTGTATTGCAGGACCCCTTCCCCCAGCAGCCAAGCCccctcttctctccctcccgccctggctcagctcccgcggccccgcccgtcccccctcccAGGACTGGTCTGTTGTCTTTTCATCTGTTCAAGAGGAGATTGAAACTGAAAACAAAATGAGAACAACAAAAAAAATTGTATGGCAGTTTTTACTTTTTATCGCTCGTTTTTAACTTCACAAATAAATGATAACAAAACCTCCCCGTCTGCGGGTGCTGTCTGTCTCCCCCCCTTTCCTTCCCTCCCTGTAGTTTTGAAGCGGATGTTTGTTCTTTATAGATGTTGTTTAAAAAGCCTGATAATGGTGATTGAAATTTACAAACTTTGTGTTTTTTTTTTTTTAAGAAAAATATAAAATAGTTTTCTTCAGGCTCAATGTGCTTTCCTAACCGTGCCCCCCCCCCTTTTTTTTTTTTGTTAAATAAAGTGCTTTTTGTTTAAAAAAGA

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