RCPedia: Rtcs

Summary

Retrocopy Name	ME2P1	Plot displaying the genomic locations of a retrocopy (in chr9) and its respective parental gene (in chr18). Each line represents a retrocopy.
Species	Homo sapiens
Coordinates (hg38)	chr9:29824071-29826679 UCSC
Coordinates (T2T)	chr9:29837282-29839890 UCSC
Coordinates (hg19)	chr9:29824069-29826677 UCSC
Strand	-
Parental Sequence	NM_002396.5
Parental seq. overlap	2417 bp
Parental seq. overlap (%)	26.7%
Genomic Region	Intergenic
Retrocopy Summary	ME2P1, located on chr9:29824071-29826679, is a retrocopy of the parental gene ME2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name	ME2
Full Name	malic enzyme 2
Also known as	ODS1
Coordinate	chr18:50879118-50954257
Strand	+
Gene summary	This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009]

Homology

Species	Scientific Name	Retrocopy
Gorilla	Gorilla gorilla	ME2P1
Orangutan	Pongo abelii	ME2P1
Gibbon	Nomascus leucogenys	ME2P1
Green monkey	Chlorocebus sabaeus	ME2P1
Crab-eating macaque	Macaca fascicularis	ME2P1
Rhesus	Macaca mulatta	ME2P1
Baboon	Papio anubis	ME2P1
Golden snub-nosed monkey	Rhinopithecus roxellana	ME2P1
Marmoset	Callithrix jacchus	ME2P1
Chimpanzee	Pan troglodytes	Without Homology
Bonobo	Pan paniscus	Without Homology
Mouse lemur	Microcebus murinus	Without Homology
Mouse	Mus musculus	Without Homology
Rat	Rattus norvegicus	Without Homology
Chinese hamster	Cricetulus griseus	Without Homology
Rabbit	Oryctolagus cuniculus	Without Homology
Pig	Sus scrofa	Without Homology
Cow	Bos taurus	Without Homology
Sheep	Ovis aries	Without Homology
Dolphin	Tursiops truncatus	Without Homology
Horse	Equus caballus	Without Homology
Dog	Canis familiaris	Without Homology
Panda	Ailuropoda melanoleuca	Without Homology
Cat	Felis catus	Without Homology
Pale spear-nosed bat	Phyllostomus discolor	Without Homology
Velvety free-tailed bat	Molossus molossus	Without Homology
Greater mouse-eared bat	Myotis myotis	Without Homology
Kuhl's pipistrelle	Pipistrellus kuhlii	Without Homology
Greater horseshoe bat	Rhinolophus ferrumequinum	Without Homology
Egyptian rousette	Rousettus aegyptiacus	Without Homology
Sloth	Choloepus didactylus	Without Homology
Tasmanian Devil	Sarcophilus harrisii	Without Homology
Opossum	Monodelphis domestica	Without Homology
Platypus	Ornithorhynchus anatinus	Without Homology
Chicken	Gallus gallus	Without Homology
Turkey	Meleagris gallopavo	Without Homology
Zebra Finch	Taeniopygia guttata	Without Homology
Budgerigar	Melopsittacus undulatus	Without Homology
Painted Turtle	Chrysemys picta	Without Homology
Lizard	Anolis Carolinensis	Without Homology
Frog	Xenopus tropicalis	Without Homology
Zebrafish	Danio rerio	Without Homology
Drosophila	Drosophila melanogaster	Without Homology

Expression

Related Sequence

>ME2P1
GTGTGGGGCCTCCCGCGCCAGTGCGAGTCTGAGTTGGCGTGGACTCCAGGAGGCTCGCAGAAGGGGAGGGCCCGGCGGCGCGAGAGCTTAGCATCGCCAGGGCGGGCGGCAAAGCGCTGCCTCTTTGCCCACAGCACCGCCTGTTGTGGCGCCAGACCTCTGGTGAAAGAAAAGATGTTGTCCGGGTTAAGCGTAGTTTCCACCACTTGTACTTTGGCATGTCTACATTTACACATAAAAGAAAAAGGCAAGCCACTTATGCTGAATCCAAGAACAAACAAGGGAATGGCATTTACTTTACAAGAACGACAGATGCTTGGTCTTCAAGGGCTTCTACCTCCCCAAATACAGACATAAGATATTCAAGCCTTACGATTCCATAGAAACTTGAAAAAAATGACTAGCCCTTCGGAAAACTATATCTACATAATGGGAATACAAGAAAGAAATGATAAATTGTTTTATAGAATACTGCAAGATGACACGGAGAGTTTAATGCCAATTGCATATACACCGACGGTTGGTCTTGTCTGCTCCCAGTGTGGACACCTCTTTAGAAGACCTAAGGGATTATTTATTTCCATCTCAGACAGAGGTCATGTTAGATCAATTGTGGATAAGTGGCCAGAAAATCATGTTAAGGCTGTTTTAGTGACTGATGGAGAGAGAATTCTGGGTCATGGAGATCTGGGTGTCTATGGAATGGGAATTCCAGTAGGAAAAATTTGTTTGTATACAGTTTGTCCAGGAATATGGCCTGATAGATGCCTTCTGGTGTGTATTGATGTGGGAGCTGATAATATCGCACTCTTAAAAGGCACATTTTACATGGGCTTGTACCAGAAACGAGATCGCACACAACAGTCTGATGATCCAATTGATGAGTTTATGAAAGCTATTACTGACAGATATGGCTGGAACACACTCCTTCAGTTTGAAGGTTTTGGACATCATAATGCATTCAGATTCTTGAGAAAATACCAATAAAAATGTTGCACTTTCAATGATGATATTCAAGGGACAGCTGCAGTAGCTCTAATAGGTCTTCTTGCAACACAAAAAGTTACTAGTAAACCAATCTCCGAACACAAAATCTTATTCCTTGGAGCAGGAGAGATTACTCTTAGAATTGCAAATCTTGTAGTATGTCTATGGTAGAAAATGGCCTGTCAGAAGAAGAGGCACAAAAGAAAATCTGGATGTTTGACAAGTATGGTTTATTAGTTTAGGGGCAGAAAGCAAAAATAGATTGTTATCAGGAACCATTTACTTACCCAGTCCCAGAGAGCATACCTGATACTTTTGAAGATGCAGTGAATATAATGAAGACTTCAACTACAATTGGAGTTGCAGGTGCTGGCCGTCTTTTCACTCCTGATGTAATCAGAGCCATTGGCTGTATCAATGAAAGGCCTGTAATATTTGCATTAAGTAATCCTACAGCACAGGCGGAGTGCAGGAGTGCACGGCTGGAGAAGCATATACACTTACAGAGGGCAAATGTTTGTTTGCCAGTGGCAGTCCATTTGGGCCAGTGAAACTCACAGATGGGCGAATCTTTACACCAGATCGAGGAAACAATGTATATATTTTTCCAGGTGTGACTTTAGCTGTTATTCTCTGTAACACCCAGCAAATTAGTGACAATGTTTTCCTAGAAGCTGCAAAGGCATTGACAAGCCACGTGACGGATGACGCGCTAGCCCGAGGGAGACTTTACTTACCACTTGCTAATATTCAGAAAGTTTCTATTAACATTGCTATTAAAGTTACAGAATACCTGTATGCTAATAAAATGGCTTTCTCAATACCCAGAACCTGAAGACAAGGCCCAATATGTTAAAGAAAGAATATGATGGAGTGAATATGATTCCCTGCTGCCAGATGTGTGTGAGTGGCCAGAATCTGCATCAAGCCCTCCTGTGATAACAGAATAGAAGCATTCCCCTGATAAATACTTTCTGTGCTCCAGGGAACCCCTTTTTTCAGACAAGAAGAGATAATGTCCTCAGTTTTATGGTGTTTTCTGTGTTTTGTTCTCCTGACCACTTTGGTTAACATATTTGTTCCATATGTCTCCACATCTGTTGGGGTAGACATGTTGATGGATTGCATTGCCCACCAGCACCCTACAATCAGTTAATTGTGATGCTTTAATTCTAACATAAAGACCATACCACATCCAGGAGATGGAAAAAGGATGTTTGTGAATGTCTTCACTTGTACTCTAATTCAGACTTGCCAAAGTACTTGCTATTTACTATTATGGGTAATAATCCTCTCTCACCTAGTTCTTTTAGAGCTACTAAAATAGAAATTTACTTTTATGTATAGAAGTGCAGAATTTGGGAAAGAAACTAAATTTTCACCAAATTCAAGGAAAAATGGTCAGTATCTAAAAATGTTCTTCTATGTCTGCTTCATCTTTCCTTCATACTCTGAAATTCTCTTACAGAAGACAGAGCTAGAGAAATATTAAAAATTTACTCTATTTATTTTCTGGAACTAAATCAAGGCTTGGCTATAACATTATGAGAGTAATGGGAACTACTGCTGCCTTTAAATAAATAAAAGTCATTGTTTTCAACAGTGTATAAAAATCACAGTGA

>NM_002396.5
CTCTCGGCCGCTCTTCGGGCCGCCTCTGCGTGTGGGGCCGCCCGCGCCAGTGTGAGCCTGAGCTGACGGCGGCTCCGGGAGGCTCGCAGAAGGGGAGGGCCGGGCGGCGCGGGAGCTGAGCATCGCCAGGGCGGGCGGCAGGGCGCGGCCTCTCCGCCGGGTGTACCACCTGTCGCGGCGCGAGACCTCTGGTGAAAGAAAAGATGTTGTCCCGGTTAAGAGTAGTTTCCACCACTTGTACTTTGGCATGTCGACATTTGCACATAAAAGAAAAAGGCAAGCCACTTATGCTGAACCCAAGAACAAACAAGGGAATGGCATTTACTTTACAAGAACGACAAATGCTTGGTCTTCAAGGACTTCTACCTCCCAAAATAGAGACACAAGATATTCAAGCCTTACGATTTCATAGAAACTTGAAGAAAATGACTAGCCCTTTGGAAAAATATATCTACATAATGGGAATACAAGAAAGAAATGAGAAATTGTTTTATAGAATACTGCAAGATGACATTGAGAGTTTAATGCCAATTGTATATACACCGACGGTTGGTCTTGCCTGCTCCCAGTATGGACACATCTTTAGAAGACCTAAGGGATTATTTATTTCGATCTCAGACAGAGGTCATGTTAGATCAATTGTGGATAACTGGCCAGAAAATCATGTTAAGGCTGTTGTAGTGACTGATGGAGAGAGAATTCTGGGTCTTGGAGATCTGGGTGTCTATGGAATGGGAATTCCAGTAGGAAAACTTTGTTTGTATACAGCTTGTGCAGGAATACGGCCTGATAGATGCCTGCCAGTGTGTATTGATGTGGGAACTGATAATATCGCACTCTTAAAAGACCCATTTTACATGGGCTTGTACCAGAAACGAGATCGCACACAACAGTATGATGACCTGATTGATGAGTTTATGAAAGCTATTACTGACAGATATGGCCGGAACACACTCATTCAGTTCGAAGACTTTGGAAATCATAATGCATTCAGGTTCTTGAGAAAGTACCGAGAAAAATATTGTACTTTCAATGATGATATTCAAGGGACAGCTGCAGTAGCTCTAGCAGGTCTTCTTGCAGCACAAAAAGTTATTAGTAAACCAATCTCCGAACACAAAATCTTATTCCTTGGAGCAGGAGAGGCTGCTCTTGGAATTGCAAATCTTATAGTTATGTCTATGGTAGAAAATGGCCTGTCAGAACAAGAGGCACAAAAGAAAATCTGGATGTTTGACAAGTATGGTTTATTAGTTAAGGGACGGAAAGCAAAAATAGATAGTTATCAGGAACCATTTACTCACTCAGCCCCAGAGAGCATACCTGATACTTTTGAAGATGCAGTGAATATACTGAAGCCTTCAACTATAATTGGAGTTGCAGGTGCTGGCCGTCTTTTCACTCCTGATGTAATCAGAGCCATGGCCTCTATCAATGAAAGGCCTGTAATATTTGCATTAAGTAATCCTACAGCACAGGCAGAGTGCACGGCTGAAGAAGCATATACACTTACAGAGGGCAGGTGTTTGTTTGCCAGTGGCAGTCCATTTGGGCCAGTGAAACTTACAGATGGGCGAGTCTTTACACCAGGTCAAGGAAACAATGTTTATATTTTTCCAGGTGTGGCTTTAGCTGTTATTCTCTGTAACACCCGGCATATTAGTGACAGTGTTTTCCTAGAAGCTGCAAAGGCCCTGACAAGCCAATTGACAGATGAAGAGCTAGCCCAAGGGAGACTTTACCCACCGCTTGCTAATATTCAGGAAGTTTCTATTAACATTGCTATTAAAGTTACAGAATACCTATATGCTAATAAAATGGCTTTCCGATACCCAGAACCTGAAGACAAGGCCAAATATGTTAAAGAAAGAACATGGCGGAGTGAATATGATTCCCTGCTGCCAGATGTGTATGAATGGCCAGAATCTGCATCAAGCCCTCCTGTGATAACAGAATAGAAGCACTCCCCTGATAAATACTTTCTGTGCTCCAGGGAACCCCTTTTTTCAGACAAGAAGAGATAATGTCTTCAGTTTTATGGTGTTTTCTGTGTTTTGTTCTCCCTGACCACTTTGGTTGATGTATTTTTTCCATGCGTCTCCACATCTGTTGGGGTAGACGTGTTGATTGATTGCATTGCCCACCAGCACCCTACAGTCAGATAGTTGTGATGCTTTAATTCTAACATACAGCCCGTACCACATCCAGGAGATGTAAAAAGTGTGTTTGTGAATGTCTTCACTTGTACTCTAATTCAGACTTGCCAAAGTATTTGCTATTTACTATTATGGGTAATACTCTTCTCTGGCCTAGTTCTTACAGAGCTACTAAAATAGAAATTTACTTTTATGGATAGAAGTACAGAATTTTGAGAAGAAACTAAATTTTCACCAAATTTTAAGGAAAAATTGTCATTATCTAAAAATGTTCTTATATATCTGCTTCATCTTACCTTCATACTCTGAAATTCCCTATAGCAGACAGAGCTAGGGAAATATTAAAAATTTACCCTATTTATTTTCTGGAACTAAATCAAGCCTTAACTATAACATTATGAGAGTAATGGGAACTACTGCTGGCTTTAAGTAAATAAAAGTCATTGTTTTCAACAGTGTATAAAAATCATAGTGTAACCTTTTTATTTAATAAATATCTTACATTTAATTGCTTCAGTTATGCTATCTTATTGCCCAACTAGAAATTTAGATTTGCTTATGAAAAACACATATTTTTGTTACTTCTAGATGATTCTAGGAGGGAGTATAAGATACCTAATCATATGGGaacatcacgtgactttttaaatctaaattagtcatgcttcacatcaaaatgagtcatatttaactggagaaactatgcccttattccagaactgatgctctttattgcttgagataattttggaatgttactatgatactgtttctttgaatatcattagtagtgacaactctttctccattgaaggcagacttaatttttttaaaccaccaacattaatttagagctaaatggggatgaataaggttggtgttcatctgggaaatgccttttttaatcccagtaaaatgggtaataatggctatccagaacagttttcttgtgtggcttgcatattgaagaattctaaaggaaaaTATATCTGCCTACCATGCTTGCTCTTAGGGAAGAAAACTTAAATGCTCATTCTAGGATAGTAACAACAACAGATAATTCATCGATAATATGAGCATGCACAGTATTTGATATTGCTCTGTAGGAAAAAAGAGACTTCATTTTTTTCATCTTCTGCCTATGAATACAAATTGAttctttttttttttttttttttttgagacagagtctcactctgttaccaggctggagtgcagtggtgtgatctcagctcactgcaacctctgcctcccaggttcaagcagttctcctgcctcagcctcccaagtagctgggactacaggtacacgccaccacgcccagctaatttttgtatttttagtagagacgggatttcaccatgttggccaggagggtctcgatttcctgacctcgcgatccgcccacctcagccttccaaagtgctgggattacaggcgtgagccaccgcacccagccAAttttttttttttttttttttgagacagagtctcgcttttgtcgcccagtctggagtgtagtggcatgatctctgcaacctctgcctcctcggttcaggcgattcttctgccttagcctcccaagtagctgggattacaggcaccggccaccacacccagctaatttttgtatttttagtagagatggggtttcaccatgttggccaggctggtctcaaaatcctgacttcaggtgatccacccactttggcctcccaaagtgctgggattacaggcgtgagccaccacacctggtcCAATTCATCATAATTCTGAATATAATTTAATAATTTTAAAATGGTCGCAATGGCATTGCCATTTGGAGTATGGGAAAATGCAGTTGGTTAATTCATTGAACAGATTAGTAAAGTCAGAAGTCTTTTTCATAACATACGGTCACAATTCCTTTCTTTTAATTAAAGACAAAAGGTTTATGGGttttggtttgtttgttttagatatggggttttgctatgtcacccttgctggagggcggtggctgttcacaggcgtgggtcatagagcactgcagcctggaactcctgggttcaagctctcctcctgcctcagcctcctgagcagcttggactaaaggtgtgcaccaccgcacctggcTGAGAGGCTTCTGTTTTTCATGTTCCCTTTATCAAAACAAAATCACGCCTAAACATACTCTCTGTGTGAAATCTTGATTTTAGTTCAACCTAAGAAATATAATAAATATAAACCTGTTTCTTGCTTAGTGTTTATTGAAGGCAGGAACGTATGCTGAATTAAAGTAATTTTACTACGAAGTTTGCTTATTAAGTATGCCTGGTACAGTCTTCATGGAAGTTATTAAGTATTTTAAGGAAAAAAATAGGCTAAATGGCATATAGCCTGCTTAAATAAAATAATTCTATTTTTTTAAAAAGCTCCCAATTGTCATTGTTATTTACCAGTCAATCTTTCAACAAGTATCAATTATTGGATGTAAATTAAAGTAAAATTGCTTAATATTTAAGCTAAGAATACAGGAAGGACTATGAGCATTGAGGAAATCGGGGGAGGCCAGAATGGCATCAAGCTGGAAAAGAAATTAAAACATTACCTTCGATGAGACTTTACCTAGCAAGAAGGTAATTATTTTGAATAACAGCAATAGAGAATCTTTTATTTTGAATTGAGAAGAAATTCTGATGATTAGAGTGTCAGTAAGTAGTAGGAAAAGGTAAGAATACATGTGTTTCTAATCTCCCACCACCACCTGTTGTATGGAACAAATTGGATTACTAGCAAGGGTAAGGTTTATTGACAATGAGAAGTTTTAGTCCAAGATTTTAGTTAAAATATTTTAAAATTTTTTGATTCATAACCAAGAAGTTGCCTCAGATCACTGTGAAGCTTTAAAATGCAGGTGCCTTTGCTCCTCCTCCCTCCAGGCCCCCGGGGGCAGAGCCCTGGCTGGTGTCTCTTCAGGAGGACCCCTGACACACCGATTCTGCCCTCACAATCACTGCCTTAAAGCAGGCAGCAgaatcttttggagaactaacaagattctgatgctgatgcatagggcctggggtggggcctcagattctgcttttttttttttttttttttttttttttAAACAGGGTCTCTTTCTTTTTCctttctcactcaggctgcagtgagtggcgtgatcttggctcactgcaacctccacttcctgggctcaaacgatcctcccgcctcagcctcctgagtagctgggactataggcgcaagtctatgcaaccacccagctaatttttgtatttttagaagagtgggggttttgccacgttgcctgggctggtctcgaactcctgacctcaagtgatccaaccacctcagcctcccaaagtgctggaattacaggcatgagccactgcacccagccAagaatgtccacttctgacaagctcccaggtgatgcctatgctgctggtacagtgaacaacatgctgagaggcattgCTCCAGGATACTGCATGTAGTGAGCAGTTCTTTAGCGTTTATGTGTCATATACTTCAAGTTACATGAAAAAGATCAACTGAAATTATGTTCTTACACAGAATAGTTTTCATCTAGTTTTATTATGTTTTTACAGGCTGTTTACAAGAACAAAAATAGAGAATTTTTGAACATATTTTTCTGAAAACATAAAAACTAGAGTACTCTTTAATTCTAAATTATAGATTTGTAGCATACTTAGTAAACTTAGTAACCAATTTTCATTTGTAAAAGATTAGCTATCAAATGGACATTTATTTCTCTTAGTTTTCTTATGACATGACTTGCCTTATATCCTTTGTCCTTTTTCTGTAACTTGTCAGCCTCTGGAGAAATAGGATTTTACATTTTTGCAAATGAGTTGCCAATGAATTAAGATCAAAACGTCATTATTAAGGAGTATGAAGCATTATTTACTGGCTCTCAGATAACAGAAAACCCAAAAGGGATGGTGGCGGAGTGAAGAAAGCCTTGCCTTGGGAAAAATACTTCAAATGCTCCCATAGTTTTTTTTCCTCAAGCCCAGTCAGTATCCTTCAAGGATAACTTTTTCATACCTTTTTTTTGGTTTGTTTGTTTCTGCTAGCTTTATGACAGAGGTTATAATAttcttttctcctctcttctttgacgtgttacgttgtctttttttttttttttttaacttcttCATACTCTTAAAAAGCTCCAGAATggccaggcgcagtggctcacgcctataatcccagcactttgggaggccaaggcaggcggatcacgaggtcaggagatcaagaccatcctggctgacacggtgaaaccctgtctctactaaaaatacaaaaacttagccaggcgtggtggcgggcgcctgtagtcccaggtactcgggagtctgaggagtgaacccgggaggtggaggttgcagtgagctgagatcgcaccgctgcactccagcctgggcgacagagtgagcctccatctcaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaTCTCCAGGGTTCTGTTGAATTCACCAAAATGGGGTCAGCTCTGGTGAGCCTATGTAATACTCGAGAACATTAATATAAACCCATAGCTCTTTACTGGGCTTCCATTTAAAGGGAAGTCCTAAGAATGAAATGGCACCAGCATCCTGTTTCCATCCAAGACAAGACCACACGTGTTCAGGTGCCATGTATTCATATAGCTCTCAACTGATTGGTGATTTGCACTTTGTGCATCTAATTATTAAAATGAAACTCTCTACAGGTGAGCTGAAGTAACATACTTCATATTTAAAAAGTTCACAGCAATTTGACCATAGAAAACTTTCTCATCTGAAATCAGGGTAAGTTTTTTTAATGTAAGCAGAGAAAAAAATAAAGCAGTGTTTTATTTCAAATTTCAGTAAGTTCAGGTGGGCCTAATTAAGACATGACTATTATTACAAATCCTATTCTTGCCAGAAGTTACTTAGATAGATTAGTGATTAGATTTTAAAAACATTATTTTCCTTTCTTGAATAAGGAAAATTGTGCATCTCAAAGAGAAAAGTAAATATGGAAATATGTTCATAGTTCAGTTGCATAAAATAGACACATTAAGTCAAGTGATTTGAATGCTTAGTGTCTTTTGGTAAACAGCATTTTGTCAACAAACTTTTCATATGGCTATAGAATCTTGTTTTTTCCAAATAAAAACTTTGCAATTGGGAGTTATTCCTCCATTCAGCACACTTTTTAATGTTAAGACTAGGGGAAACTTGTGGGTATATATTCAGTGGTTTTCAGGATTTTCTTTTATGTTCTAGAAAAGTAATTTTTCCTTTCCTAGTTTTAAGTATATATTCAAGCAAATCGTTGATTCCTATACAGCCATTGGATTATCACCAACACATTTGGTATATACAGTGGGCCGATAATGACAaactaaagtttgtggttaatacctactctataccagacactgttctaaggatccgacatatttaatcctctgtttaccctctgtttctgtgcctgatttacagacagagacagaggcacagagaggttaaatgacttgtcaaaggtcttatgatgtgtggcagagcctgggtttttagctcaaacCCCTCTCAGTGAAGAAAGCCTTCTGTGTAGGCAATTTCATCTAATACCTTCATGAATTGTTACTTCAGATGAGAATTCTCACTTAttcttttttttttttttttttcttttctttgagacagccttgctctgtctcccaggctggagtgcagtggcgcaatctcagctcactgcaagctccgcctcccgggttatgccattctcctgcctcagccttccgagtagctcggactacaggcgcccgccacctcgcccagctaattttttgtatttttagtagagacggggtttcaccgtgttagccaggatggtctcgatctcctgacctcatgatccacccgcctcggcctcccaaagtgctgggattacaggcgtgagccaccgcgcccggccTCACTTAGTCTTTTACCAGTTCATCTGATTTTTACTTTGTTCCCATTTATAATTCAAATATAATATAAACGTCTTATTCATTTAGTCTTCAGCATTTTAAGTATTCGACACGAACATTAAAGATTTGGTGTTGAATTTAATAAATTACACCAAAAAGTCTCAGTAGCCAATTCACTAACATCTTTTGATTTGGTAATCTTCACAGAATCAACAACTGTTAACACTTCTGTGCAAATAAATTTCAGTTGTGCTTATATATTATAATATTCACTTTAGGAATCCACCTGTCAATTTGCAATTCAATTATAAGGTATATTTTAAGTGATATCTATGTATTGTATACACATATTCCATTGAAAGGTGAGAATAATTAGAAAGTAGTAATATAAAAATGTGTATGAAATAAGAACTTTCTTAAAAGACCTAGTTTAGCTAAATATATGACAATATAAAATGTCTGCCCAATGTTTTATTATACTTTGTCTAATGACCTTTAAATTTAACTGAAATTAAAACCGTACTTTTGCAGTTGATATTTTTGTGTTCCCTTTGTTAACATACCAAGCACTAATTATTGACTTCAAGGAAGCCACGTATTGCAAGTCATTGCTTAGCCTTTCACATCTGAGTGTTGATAAGATGACGGAATGGGTAGTCTTGTAGTAATTGCTTATGGGAATGCTAGTTTAAGAGGAATGCCTTGTATAGAACATATTATACCAGATTGACTTGTTAAAAATGGTTCCAAGAATCAGTCTAAAAACTTCAGAATTATGTGAATTATTTTTTCTCTGTTGTGATATGTTGTAATGAGATGTGTGTTCTTATATTTTCTTAGTAAAATTTTCTTAAGCATAAAA

>NM_002396.5 

CTCTCGGCCGCTCTTCGGGCCGCCTCTGCGTGTGGGGCCGCCCGCGCCAGTGTGAGCCTGAGCTGACGGCGGCTCCGGGAGGCTCGCAGAAGGGGAGGGCCGGGCGGCGCGGGAGCTGAGCATCGCCAGGGCGGGCGGCAGGGCGCGGCCTCTCCGCCGGGTGTACCACCTGTCGCGGCGCGAGACCTCTGGTGAAAGAAAAGATGTTGTCCCGGTTAAGAGTAGTTTCCACCACTTGTACTTTGGCATGTCGACATTTGCACATAAAAGAAAAAGGCAAGCCACTTATGCTGAACCCAAGAACAAACAAGGGAATGGCATTTACTTTACAAGAACGACAAATGCTTGGTCTTCAAGGACTTCTACCTCCCAAAATAGAGACACAAGATATTCAAGCCTTACGATTTCATAGAAACTTGAAGAAAATGACTAGCCCTTTGGAAAAATATATCTACATAATGGGAATACAAGAAAGAAATGAGAAATTGTTTTATAGAATACTGCAAGATGACATTGAGAGTTTAATGCCAATTGTATATACACCGACGGTTGGTCTTGCCTGCTCCCAGTATGGACACATCTTTAGAAGACCTAAGGGATTATTTATTTCGATCTCAGACAGAGGTCATGTTAGATCAATTGTGGATAACTGGCCAGAAAATCATGTTAAGGCTGTTGTAGTGACTGATGGAGAGAGAATTCTGGGTCTTGGAGATCTGGGTGTCTATGGAATGGGAATTCCAGTAGGAAAACTTTGTTTGTATACAGCTTGTGCAGGAATACGGCCTGATAGATGCCTGCCAGTGTGTATTGATGTGGGAACTGATAATATCGCACTCTTAAAAGACCCATTTTACATGGGCTTGTACCAGAAACGAGATCGCACACAACAGTATGATGACCTGATTGATGAGTTTATGAAAGCTATTACTGACAGATATGGCCGGAACACACTCATTCAGTTCGAAGACTTTGGAAATCATAATGCATTCAGGTTCTTGAGAAAGTACCGAGAAAAATATTGTACTTTCAATGATGATATTCAAGGGACAGCTGCAGTAGCTCTAGCAGGTCTTCTTGCAGCACAAAAAGTTATTAGTAAACCAATCTCCGAACACAAAATCTTATTCCTTGGAGCAGGAGAGGCTGCTCTTGGAATTGCAAATCTTATAGTTATGTCTATGGTAGAAAATGGCCTGTCAGAACAAGAGGCACAAAAGAAAATCTGGATGTTTGACAAGTATGGTTTATTAGTTAAGGGACGGAAAGCAAAAATAGATAGTTATCAGGAACCATTTACTCACTCAGCCCCAGAGAGCATACCTGATACTTTTGAAGATGCAGTGAATATACTGAAGCCTTCAACTATAATTGGAGTTGCAGGTGCTGGCCGTCTTTTCACTCCTGATGTAATCAGAGCCATGGCCTCTATCAATGAAAGGCCTGTAATATTTGCATTAAGTAATCCTACAGCACAGGCAGAGTGCACGGCTGAAGAAGCATATACACTTACAGAGGGCAGGTGTTTGTTTGCCAGTGGCAGTCCATTTGGGCCAGTGAAACTTACAGATGGGCGAGTCTTTACACCAGGTCAAGGAAACAATGTTTATATTTTTCCAGGTGTGGCTTTAGCTGTTATTCTCTGTAACACCCGGCATATTAGTGACAGTGTTTTCCTAGAAGCTGCAAAGGCCCTGACAAGCCAATTGACAGATGAAGAGCTAGCCCAAGGGAGACTTTACCCACCGCTTGCTAATATTCAGGAAGTTTCTATTAACATTGCTATTAAAGTTACAGAATACCTATATGCTAATAAAATGGCTTTCCGATACCCAGAACCTGAAGACAAGGCCAAATATGTTAAAGAAAGAACATGGCGGAGTGAATATGATTCCCTGCTGCCAGATGTGTATGAATGGCCAGAATCTGCATCAAGCCCTCCTGTGATAACAGAATAGAAGCACTCCCCTGATAAATACTTTCTGTGCTCCAGGGAACCCCTTTTTTCAGACAAGAAGAGATAATGTCTTCAGTTTTATGGTGTTTTCTGTGTTTTGTTCTCCCTGACCACTTTGGTTGATGTATTTTTTCCATGCGTCTCCACATCTGTTGGGGTAGACGTGTTGATTGATTGCATTGCCCACCAGCACCCTACAGTCAGATAGTTGTGATGCTTTAATTCTAACATACAGCCCGTACCACATCCAGGAGATGTAAAAAGTGTGTTTGTGAATGTCTTCACTTGTACTCTAATTCAGACTTGCCAAAGTATTTGCTATTTACTATTATGGGTAATACTCTTCTCTGGCCTAGTTCTTACAGAGCTACTAAAATAGAAATTTACTTTTATGGATAGAAGTACAGAATTTTGAGAAGAAACTAAATTTTCACCAAATTTTAAGGAAAAATTGTCATTATCTAAAAATGTTCTTATATATCTGCTTCATCTTACCTTCATACTCTGAAATTCCCTATAGCAGACAGAGCTAGGGAAATATTAAAAATTTACCCTATTTATTTTCTGGAACTAAATCAAGCCTTAACTATAACATTATGAGAGTAATGGGAACTACTGCTGGCTTTAAGTAAATAAAAGTCATTGTTTTCAACAGTGTATAAAAATCATAGTGTAACCTTTTTATTTAATAAATATCTTACATTTAATTGCTTCAGTTATGCTATCTTATTGCCCAACTAGAAATTTAGATTTGCTTATGAAAAACACATATTTTTGTTACTTCTAGATGATTCTAGGAGGGAGTATAAGATACCTAATCATATGGGaacatcacgtgactttttaaatctaaattagtcatgcttcacatcaaaatgagtcatatttaactggagaaactatgcccttattccagaactgatgctctttattgcttgagataattttggaatgttactatgatactgtttctttgaatatcattagtagtgacaactctttctccattgaaggcagacttaatttttttaaaccaccaacattaatttagagctaaatggggatgaataaggttggtgttcatctgggaaatgccttttttaatcccagtaaaatgggtaataatggctatccagaacagttttcttgtgtggcttgcatattgaagaattctaaaggaaaaTATATCTGCCTACCATGCTTGCTCTTAGGGAAGAAAACTTAAATGCTCATTCTAGGATAGTAACAACAACAGATAATTCATCGATAATATGAGCATGCACAGTATTTGATATTGCTCTGTAGGAAAAAAGAGACTTCATTTTTTTCATCTTCTGCCTATGAATACAAATTGAttctttttttttttttttttttttgagacagagtctcactctgttaccaggctggagtgcagtggtgtgatctcagctcactgcaacctctgcctcccaggttcaagcagttctcctgcctcagcctcccaagtagctgggactacaggtacacgccaccacgcccagctaatttttgtatttttagtagagacgggatttcaccatgttggccaggagggtctcgatttcctgacctcgcgatccgcccacctcagccttccaaagtgctgggattacaggcgtgagccaccgcacccagccAAttttttttttttttttttttgagacagagtctcgcttttgtcgcccagtctggagtgtagtggcatgatctctgcaacctctgcctcctcggttcaggcgattcttctgccttagcctcccaagtagctgggattacaggcaccggccaccacacccagctaatttttgtatttttagtagagatggggtttcaccatgttggccaggctggtctcaaaatcctgacttcaggtgatccacccactttggcctcccaaagtgctgggattacaggcgtgagccaccacacctggtcCAATTCATCATAATTCTGAATATAATTTAATAATTTTAAAATGGTCGCAATGGCATTGCCATTTGGAGTATGGGAAAATGCAGTTGGTTAATTCATTGAACAGATTAGTAAAGTCAGAAGTCTTTTTCATAACATACGGTCACAATTCCTTTCTTTTAATTAAAGACAAAAGGTTTATGGGttttggtttgtttgttttagatatggggttttgctatgtcacccttgctggagggcggtggctgttcacaggcgtgggtcatagagcactgcagcctggaactcctgggttcaagctctcctcctgcctcagcctcctgagcagcttggactaaaggtgtgcaccaccgcacctggcTGAGAGGCTTCTGTTTTTCATGTTCCCTTTATCAAAACAAAATCACGCCTAAACATACTCTCTGTGTGAAATCTTGATTTTAGTTCAACCTAAGAAATATAATAAATATAAACCTGTTTCTTGCTTAGTGTTTATTGAAGGCAGGAACGTATGCTGAATTAAAGTAATTTTACTACGAAGTTTGCTTATTAAGTATGCCTGGTACAGTCTTCATGGAAGTTATTAAGTATTTTAAGGAAAAAAATAGGCTAAATGGCATATAGCCTGCTTAAATAAAATAATTCTATTTTTTTAAAAAGCTCCCAATTGTCATTGTTATTTACCAGTCAATCTTTCAACAAGTATCAATTATTGGATGTAAATTAAAGTAAAATTGCTTAATATTTAAGCTAAGAATACAGGAAGGACTATGAGCATTGAGGAAATCGGGGGAGGCCAGAATGGCATCAAGCTGGAAAAGAAATTAAAACATTACCTTCGATGAGACTTTACCTAGCAAGAAGGTAATTATTTTGAATAACAGCAATAGAGAATCTTTTATTTTGAATTGAGAAGAAATTCTGATGATTAGAGTGTCAGTAAGTAGTAGGAAAAGGTAAGAATACATGTGTTTCTAATCTCCCACCACCACCTGTTGTATGGAACAAATTGGATTACTAGCAAGGGTAAGGTTTATTGACAATGAGAAGTTTTAGTCCAAGATTTTAGTTAAAATATTTTAAAATTTTTTGATTCATAACCAAGAAGTTGCCTCAGATCACTGTGAAGCTTTAAAATGCAGGTGCCTTTGCTCCTCCTCCCTCCAGGCCCCCGGGGGCAGAGCCCTGGCTGGTGTCTCTTCAGGAGGACCCCTGACACACCGATTCTGCCCTCACAATCACTGCCTTAAAGCAGGCAGCAgaatcttttggagaactaacaagattctgatgctgatgcatagggcctggggtggggcctcagattctgcttttttttttttttttttttttttttttAAACAGGGTCTCTTTCTTTTTCctttctcactcaggctgcagtgagtggcgtgatcttggctcactgcaacctccacttcctgggctcaaacgatcctcccgcctcagcctcctgagtagctgggactataggcgcaagtctatgcaaccacccagctaatttttgtatttttagaagagtgggggttttgccacgttgcctgggctggtctcgaactcctgacctcaagtgatccaaccacctcagcctcccaaagtgctggaattacaggcatgagccactgcacccagccAagaatgtccacttctgacaagctcccaggtgatgcctatgctgctggtacagtgaacaacatgctgagaggcattgCTCCAGGATACTGCATGTAGTGAGCAGTTCTTTAGCGTTTATGTGTCATATACTTCAAGTTACATGAAAAAGATCAACTGAAATTATGTTCTTACACAGAATAGTTTTCATCTAGTTTTATTATGTTTTTACAGGCTGTTTACAAGAACAAAAATAGAGAATTTTTGAACATATTTTTCTGAAAACATAAAAACTAGAGTACTCTTTAATTCTAAATTATAGATTTGTAGCATACTTAGTAAACTTAGTAACCAATTTTCATTTGTAAAAGATTAGCTATCAAATGGACATTTATTTCTCTTAGTTTTCTTATGACATGACTTGCCTTATATCCTTTGTCCTTTTTCTGTAACTTGTCAGCCTCTGGAGAAATAGGATTTTACATTTTTGCAAATGAGTTGCCAATGAATTAAGATCAAAACGTCATTATTAAGGAGTATGAAGCATTATTTACTGGCTCTCAGATAACAGAAAACCCAAAAGGGATGGTGGCGGAGTGAAGAAAGCCTTGCCTTGGGAAAAATACTTCAAATGCTCCCATAGTTTTTTTTCCTCAAGCCCAGTCAGTATCCTTCAAGGATAACTTTTTCATACCTTTTTTTTGGTTTGTTTGTTTCTGCTAGCTTTATGACAGAGGTTATAATAttcttttctcctctcttctttgacgtgttacgttgtctttttttttttttttttaacttcttCATACTCTTAAAAAGCTCCAGAATggccaggcgcagtggctcacgcctataatcccagcactttgggaggccaaggcaggcggatcacgaggtcaggagatcaagaccatcctggctgacacggtgaaaccctgtctctactaaaaatacaaaaacttagccaggcgtggtggcgggcgcctgtagtcccaggtactcgggagtctgaggagtgaacccgggaggtggaggttgcagtgagctgagatcgcaccgctgcactccagcctgggcgacagagtgagcctccatctcaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaTCTCCAGGGTTCTGTTGAATTCACCAAAATGGGGTCAGCTCTGGTGAGCCTATGTAATACTCGAGAACATTAATATAAACCCATAGCTCTTTACTGGGCTTCCATTTAAAGGGAAGTCCTAAGAATGAAATGGCACCAGCATCCTGTTTCCATCCAAGACAAGACCACACGTGTTCAGGTGCCATGTATTCATATAGCTCTCAACTGATTGGTGATTTGCACTTTGTGCATCTAATTATTAAAATGAAACTCTCTACAGGTGAGCTGAAGTAACATACTTCATATTTAAAAAGTTCACAGCAATTTGACCATAGAAAACTTTCTCATCTGAAATCAGGGTAAGTTTTTTTAATGTAAGCAGAGAAAAAAATAAAGCAGTGTTTTATTTCAAATTTCAGTAAGTTCAGGTGGGCCTAATTAAGACATGACTATTATTACAAATCCTATTCTTGCCAGAAGTTACTTAGATAGATTAGTGATTAGATTTTAAAAACATTATTTTCCTTTCTTGAATAAGGAAAATTGTGCATCTCAAAGAGAAAAGTAAATATGGAAATATGTTCATAGTTCAGTTGCATAAAATAGACACATTAAGTCAAGTGATTTGAATGCTTAGTGTCTTTTGGTAAACAGCATTTTGTCAACAAACTTTTCATATGGCTATAGAATCTTGTTTTTTCCAAATAAAAACTTTGCAATTGGGAGTTATTCCTCCATTCAGCACACTTTTTAATGTTAAGACTAGGGGAAACTTGTGGGTATATATTCAGTGGTTTTCAGGATTTTCTTTTATGTTCTAGAAAAGTAATTTTTCCTTTCCTAGTTTTAAGTATATATTCAAGCAAATCGTTGATTCCTATACAGCCATTGGATTATCACCAACACATTTGGTATATACAGTGGGCCGATAATGACAaactaaagtttgtggttaatacctactctataccagacactgttctaaggatccgacatatttaatcctctgtttaccctctgtttctgtgcctgatttacagacagagacagaggcacagagaggttaaatgacttgtcaaaggtcttatgatgtgtggcagagcctgggtttttagctcaaacCCCTCTCAGTGAAGAAAGCCTTCTGTGTAGGCAATTTCATCTAATACCTTCATGAATTGTTACTTCAGATGAGAATTCTCACTTAttcttttttttttttttttttcttttctttgagacagccttgctctgtctcccaggctggagtgcagtggcgcaatctcagctcactgcaagctccgcctcccgggttatgccattctcctgcctcagccttccgagtagctcggactacaggcgcccgccacctcgcccagctaattttttgtatttttagtagagacggggtttcaccgtgttagccaggatggtctcgatctcctgacctcatgatccacccgcctcggcctcccaaagtgctgggattacaggcgtgagccaccgcgcccggccTCACTTAGTCTTTTACCAGTTCATCTGATTTTTACTTTGTTCCCATTTATAATTCAAATATAATATAAACGTCTTATTCATTTAGTCTTCAGCATTTTAAGTATTCGACACGAACATTAAAGATTTGGTGTTGAATTTAATAAATTACACCAAAAAGTCTCAGTAGCCAATTCACTAACATCTTTTGATTTGGTAATCTTCACAGAATCAACAACTGTTAACACTTCTGTGCAAATAAATTTCAGTTGTGCTTATATATTATAATATTCACTTTAGGAATCCACCTGTCAATTTGCAATTCAATTATAAGGTATATTTTAAGTGATATCTATGTATTGTATACACATATTCCATTGAAAGGTGAGAATAATTAGAAAGTAGTAATATAAAAATGTGTATGAAATAAGAACTTTCTTAAAAGACCTAGTTTAGCTAAATATATGACAATATAAAATGTCTGCCCAATGTTTTATTATACTTTGTCTAATGACCTTTAAATTTAACTGAAATTAAAACCGTACTTTTGCAGTTGATATTTTTGTGTTCCCTTTGTTAACATACCAAGCACTAATTATTGACTTCAAGGAAGCCACGTATTGCAAGTCATTGCTTAGCCTTTCACATCTGAGTGTTGATAAGATGACGGAATGGGTAGTCTTGTAGTAATTGCTTATGGGAATGCTAGTTTAAGAGGAATGCCTTGTATAGAACATATTATACCAGATTGACTTGTTAAAAATGGTTCCAAGAATCAGTCTAAAAACTTCAGAATTATGTGAATTATTTTTTCTCTGTTGTGATATGTTGTAATGAGATGTGTGTTCTTATATTTTCTTAGTAAAATTTTCTTAAGCATAAAA

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