Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RBMXP2
Plot displaying the genomic locations of a retrocopy (in chr9) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr9:30688949-30690960  UCSC
Coordinates (T2T) chr9:30704273-30706284  UCSC
Coordinates (hg19) chr9:30688947-30690958  UCSC
Strand +
Parental Sequence NM_002139.4
Parental seq. overlap 1924 bp
Parental seq. overlap (%) 95.6%
Genomic Region Intergenic
Retrocopy Summary RBMXP2, located on chr9:30688949-30690960, is a retrocopy of the parental gene RBMX. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RBMX
Full Name RNA binding motif protein X-linked
Also known as HNRNPG|HNRPG|MRXS11|RBMXP1|RBMXRT|RNMX|hnRNP-G
Coordinate chrX:136869192-136880725
Strand -
Gene summary This gene belongs to the RBMY gene family which includes candidate Y chromosome spermatogenesis genes. This gene, an active X chromosome homolog of the Y chromosome RBMY gene, is widely expressed whereas the RBMY gene evolved a male-specific function in spermatogenesis. Pseudogenes of this gene, found on chromosomes 1, 4, 9, 11, and 6, were likely derived by retrotransposition from the original gene. Alternatively spliced transcript variants encoding different isoforms have been identified. A snoRNA gene (SNORD61) is found in one of its introns. [provided by RefSeq, Sep 2009]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RBMXP4
Bonobo Pan paniscus RBMXP4
Gorilla Gorilla gorilla RBMXP5
Orangutan Pongo abelii RBMXP4
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RBMXP2
TTCGTTGTGCAGTAGTGCTAGCGGCTTCACGGTTCGGTCCTCGGACCCGGCAGCCGCCACTGGTGCTGAGCTGTTAGGAAGCCCCTATCGGCGAGCTCATTGGAGCTTGAACCCATTGTCACCCCTCCGACTCACCGGCTGGTTGAAGCAGATTGCCCAGGAAAGCCGTTCACTGGTGGGCTTAACACGGAAACAAATGAGAAAGCTCTTGAAGCAGTATTTGGCAAATATGGACGAATAGTGGAAGTACTCTTGGTGAAAGACCATGAAACCAACAAATCAGGAGGATTTGCTTTTGTCACCTTTGAAAGCCCAGCAGATGCTAAGGATGCAGCCAGAGACATGAATGGAAAGTCATTAGATGGAAAAGCCATCGAGGTGGAACAAGCCAACAAACCATCATTTGAAAGTGGTAGACGTGGACCGCCTCCACCTCCAAGAAGTAGAGGCCCTCCAAGAGGTCTTAGAGGTGGAAGAGGAGGAAGTGGAGGAACAAGGGGACCTCCCTCACGGGGAGGACACATGGATGACGGTGGATATTCCATGAATTTTAACATGAGTTCTTCCAGGGGACCACATCCAGTAAAAAGAGGACCACCACCAAGAAGTGGGAGTCCTCCTTCTAAGAGATCTGCACCTTCAGGACCAGTTCGCAGTAGCAGTGAAATGGGAGGAAGAGCTCCTGTATCACGTGGAAGAGATAGTTACGGAGGTCCACCTCGAAGGGAACTGCTGCCCTCTTGTAGAAATGATTATTTGTCCCCAAGAGATGATGGGTATTCTACTAAAGACAGCTATTCAAGCAGAGATTACCCAAGTTCTCATGATACTAGAGCTTATGCACCACCACCACGAGATTATACTTACCGTGATTATGGTCATTCCAGTTCACGTGTTGACTATCCATAAAGAGGCTATAGCGATAGAGATAGATATGGTCGTGATCATGACTATTCAGATCATCCAGGTGGAGGTTCCTACAGAGATTCATATGAGAGTTATGGTAACTCACGTAGTGCTCCACCTACACGAGGGCCCCCACCATCTTATGGTGGAAGCAGTCGCTATGATGATTACAGCAGCTCATGTGACGGATATGGTGGAAGTCGAGACAGTTACTCAAGCAGCCGAAGTGATCTCTACTCAAGTGGTCGTGATCGGGTTGGCAGACAAGAAAGAGGGCTTACCCCTTCTATGGAAAGAGGATACCCTCCTCCACGTGATTCCTACAGCAGTTCAAGTGCGGAGCACCAAGCGGTGGTGGCTGTGGAGGAAGCCGATCTGATAGAGGGGGAGGTAGAAGCAGATACTAGAAACAAACAAAACTTTGGACCAAAATCCCAGTTCAAAGAAACAAAAAGTGGAAGCTATTCTATCATAACTACCCAAGGACTACTAAAAGGAAAAATTGTGTTACTTTTTAAAAATTCCCTGTTAAGTTCCCCTCCATAATTTTTATGTTCTTGTGAGGAGAAAAGTAAAACATGTTTAATTTTATTTTGACTTTTGCATTGCTTTTCAACAAGCAAACGTTAAATGTGTTAAGACTTGTACTGGTGTTGTAACTTTCCAAGTAAAAGTATCCCTAAAGGCCACTTCCTATCTGATTTTTCCCAGTAAATGAGGCAGGCAATTCTAAGATCTTCCACAAAACATCTAGCCATCTAAAATGGAGAGATGAATCATTCTACCTATACAAACAAGCTAGCTATTAGAGGGTGGTTGGGGTATGCTACTCATAAGATTTCAGGGTGTCTTCCAACTGAAATCTCAATGTTTTCAGTATGAAAAACCTGAAATCACATGCCTTTGTAAGGAAAGTGCTATTCACCCAGTAAACCCAAAAAAGCAAATGGATGATGCTGGCCATTTTGCCTTTCTGACATTTCCTTGGGAATCTGCAAGAACCTCCCTTTCCCCCTCCCCCAATAAGACCATTTAAGTGTGTGTTAAACAACTACAGAATACTAAATAAAAAGTTTGGCC
>NM_002139.4
CTCGTTGCGCAGTAGTGCTAGCGGCTTCGCGGTTCGGTCCTCGCACCCGGCAGCCGCCACTGGTGCTGAGCTGCTAGGAAGCCCCTATCGCCGAGCTCGTTGGAGCTTGAACCCATTGTCACCCCTCCGACTCACCGGCCCAAAAAAAAAAAAACATGGTTGAAGCAGATCGCCCAGGAAAGCTCTTCATTGGTGGGCTTAATACGGAAACAAATGAGAAAGCTCTTGAAGCAGTATTTGGCAAATATGGACGAATAGTGGAAGTACTCTTGATGAAAGACCGTGAAACCAACAAATCAAGAGGATTTGCTTTTGTCACCTTTGAAAGCCCAGCAGACGCTAAGGATGCAGCCAGAGACATGAATGGAAAGTCATTAGATGGAAAAGCCATCAAGGTGGAACAAGCCACCAAACCATCATTTGAAAGTGGTAGACGTGGACCGCCTCCACCTCCAAGAAGTAGAGGCCCTCCAAGAGGTCTTAGAGGTGGAAGAGGAGGAAGTGGAGGAACCAGGGGACCTCCCTCACGGGGAGGACACATGGATGACGGTGGATATTCCATGAATTTTAACATGAGTTCTTCCAGGGGACCACTCCCAGTAAAAAGAGGACCACCACCAAGAAGTGGGGGTCCTCCTCCTAAGAGATCTGCACCTTCAGGACCAGTTCGCAGTAGCAGTGGAATGGGAGGAAGAGCTCCTGTATCACGTGGAAGAGATAGTTATGGAGGTCCACCTCGAAGGGAACCGCTGCCCTCTCGTAGAGATGTTTATTTGTCCCCAAGAGATGATGGGTATTCTACTAAAGACAGCTATTCAAGCAGAGATTACCCAAGTTCTCGTGATACTAGAGATTATGCACCACCACCACGAGATTATACTTACCGTGATTATGGTCATTCCAGTTCACGTGATGACTATCCATCAAGAGGATATAGCGATAGAGATGGATATGGTCGTGATCGTGACTATTCAGATCATCCAAGTGGAGGTTCCTACAGAGATTCATATGAGAGTTATGGTAACTCACGTAGTGCTCCACCTACACGAGGGCCCCCGCCATCTTATGGTGGAAGCAGTCGCTATGATGATTACAGCAGCTCACGTGACGGATATGGTGGAAGTCGAGACAGTTACTCAAGCAGCCGAAGTGATCTCTACTCAAGTGGTCGTGATCGGGTTGGCAGACAAGAAAGAGGGCTTCCCCCTTCTATGGAAAGGGGGTACCCTCCTCCACGTGATTCCTACAGCAGTTCAAGCCGCGGAGCACCAAGAGGTGGTGGCCGTGGAGGAAGCCGATCTGATAGAGGGGGAGGCAGAAGCAGATACTAGAAACAAACAAAACTTTGGACCAAAATCCCAGTTCAAAGAAACAAAAAGTGGAAACTATTCTATCATAACTACCCAAGGACTACTAAAAGGAAAAATTGTGTTACTTTTTTTAAATTCCCTGTTAAGTTCCCCTCCATAATTTTTATGTTCTTGTGAGGAAAAAAGTAAAACATGTTTAATTTTATTTGACTTTCGCATTGCTTTTCAACAAGCAAATGTTAAATGTGTTAAGACTTGTACTAGTGTTGTAACTTTCCAAGTAAAAGTATCCCCTAAAGGCCACTTCCTATCTGATTTTTCCCAGCAAATGAGGCAGGCAATTCTAAGATCTTCCACAAAACATCTAGCCATCTAAAATGGAGAGATGAATCATTCTACCTATACAAACAAGCTAGCTATTAGAGGGTGGTTGGGGTATGCTACTCATAAGATTTCAGGGTGTCTTCCAACTGAAATCTCAATGTTCTCAGTACGAAAAACCTGAAATCACATGCCTATGTAAGGAAAGTGCTATTCACCCAGTAAACCCAAAAAAGCAAATGGATAATGCTGGCCATTTTGCCTTTCTGACATTTCCTTGGGAATCTGCAAGAACCTCCCCTTTCCCTTCCCCCAATAAGACCATTTAAGTGTGTGTTAAACAACTACAGAATACTAAATAAAAAGTTTGGCCAAAACCAA

Publications

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