Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TAF1L
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Plot displaying the genomic locations of a retrocopy (in chr9) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr9:32628392-32635589  UCSC
Coordinates (T2T) chr9:32644587-32651784  UCSC
Coordinates (hg19) chr9:32628390-32635587  UCSC
Strand -
Parental Sequence XM_005262295.1
Parental seq. overlap 4357 bp
Parental seq. overlap (%) 49.3%
Genomic Region Intergenic
Retrocopy Summary TAF1L, located on chr9:32628392-32635589, is a retrocopy of the parental gene TAF1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TAF1
Full Name TATA-box binding protein associated factor 1
Also known as BA2R|CCG1|CCGS|DYT3|DYT3/TAF1|KAT4|MRXS33|N-TAF1|NSCL2|OF|P250|TAF(II)250|TAF2A|TAFII-250|TAFII250|XDP
Coordinate chrX:71366220-71466005
Strand +
Gene summary Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the rate of transcription initiation. This subunit contains two independent protein kinase domains at the N- and C-terminals, but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme. Mutations in this gene result in Dystonia 3, torsion, X-linked, a dystonia-parkinsonism disorder. Alternative splicing of this gene results in multiple transcript variants. This gene is part of a complex transcription unit (TAF1/DYT3), wherein some transcript variants share exons with TAF1 as well as additional downstream DYT3 exons. [provided by RefSeq, Oct 2013]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TAF1P1
Bonobo Pan paniscus TAF1P1
Gorilla Gorilla gorilla TAF1P1
Orangutan Pongo abelii TAF1P1
Gibbon Nomascus leucogenys TAF1P1
Crab-eating macaque Macaca fascicularis TAF1P1
Rhesus Macaca mulatta TAF1P1
Baboon Papio anubis TAF1P1
Green monkey Chlorocebus sabaeus Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Adipose SubcutaneousMuscle SkeletalArtery TibialArtery CoronaryHeart Atrial AppendageAdipose VisceralUterusVaginaBreast Mammary TissueSkin Not Sun ExposedMinor Salivary GlandBrain CortexAdrenal GlandThyroidLungSpleenPancreasEsophagus MuscularisEsophagus MucosaEsophagus Gastroesophageal JunctionStomachColon SigmoidSmall Intestine Terminal IleumColon TransverseProstateTestisNerve TibialSkin Sun ExposedHeart Left VentricleBrain CerebellumWhole BloodArtery AortaPituitaryBrain Frontal CortexBrain CaudateBrain Nucleus AccumbensBrain PutamenBrain HypothalamusBrain Spinal CordBrain HippocampusBrain Anterior Cingulate CortexOvaryBrain Cerebellar HemisphereLiverBrain Substantia NigraKidney CortexBrain AmygdalaCervix EctocervixFallopian TubeCervix EndocervixBladderKidney Medulla00.51
log10(TPM+1)

Related Sequence

>TAF1L
GCTTCTGTGTTTGTTATGTATGCTGGGTGGGATATTGTGCTTTTATTTCGGTATTGTTTGAATTGTTTTACAAGTATGTATTATTTTTGTAACCTAGTTTGTTTGTTTGTAACTGCCTTGTTCCAGGAAGGATTTAAGATGGTTTATATTCCAGTCCTTTAATGCTGGAATGGCTAGAGATGAGACTGAAAGATGGGCAGGAAGTATATCATCACAAGCTTTGCATTTGATGTTAATGTGTATGATTTTTATATTATGGGAAATAAGCTCTTAGAGGAGTGATGTAATCAGGTTTGTGTTTTAGAAATCTGTGTAACGTATTTCCAAGCATGGTATCATCTCACTTTTCTAATTTACAGGCTGGAACAGATGAGAGCCCTCCTGCTGGGACAGAGAATTGGGTTCTAGTGGACTCTGCTACACTTAAACCTATGTGACAAACCGCCCATTATTTTATTGTTTATTTAATTATACAATGCCTCGTTCCTATATGGATTTGAGGCAAATTACCATAAATTTTGAAACAGCCTATATGTCAGAAATGAAAATGTTGCCATCTAAAAACCTAAGCCTCCAGCCCCAGAAGGGGGAGATGGTGATCTTGCAGATGAAGAGGAAGGAACTGTACAACAACCTGAAGCCAGTGTCCTGTATGAGGATTTGCTTATATCTGAAGGAGAAGATGATGAGGAAGATGCTGGGAGTGACGAAGAAGGAGACAATCCTTTCTCTGCTATCCAGCTGAGTGAAAGTGGAAGTGACTCTGATGTGGGATATGGTGGAATAAGACCCAAACAACCCTTCATGCTTCAGCATGCTTCAGGAGAACACAAGGATGGGCACGGAAAATGAAGAAAGCATGATGTCCCATGAGGGAGACGGTGGGGAGGCTTCCCATGATTTGGAGGATAGCAACATCAGTTATGGGAGCTGTGAGGAGCCTGATCCCAAGTTGAACACCCAAGACACAAGCTTCAGCAGCATCGGAAATTTCCATTCACGCTGCTCCTTGGAACACCACAAGGGCCTTCATTGCTGCCATGAAGGGCAAGTGTCTCCTAGAGGTGACTGGGGTGGCAGATCCCACAGGGTGTGGTGAAGGATTCTCCTATGTGAAGATTCCAAATAAACCAACACAGCAGAAGGATGATAAAGAGCCACAGGCAGTGAAGAAGACAGTGACAGGAACAGATGCAGACCTTCGTCGCCTTTCCCTGAAAAATGCCAAGCAACTTCTACGTAAATTTGGTGTGCCTGAGGAAGAGATTAAAAAGTTGTCCCGCTGGGAAGTGATTGATGTGGTGCGCACAATGTCAACAGAACAGGCTCATTCTGGAGAGGGGCCCATGAGTAAATTTGCCCGTGGATCAAGGTTTTCTGTGGCTGAGCATCAAGAGCGTTACAAAGAGGAATGTCAGCGTATCTTTGACCTACAGAACAAGGTTCTGTCATCAACTGAGGTCTTATCAACTGACACAGACAGCATCTCAGCTGAAGATAGTGACTTTGAAGAAATGGGAAAGAACATTGAGAACATGTTGCAGAACAAGAAAACCAGCTCTCAGCTGTCACGTGAATGGGAGGAGCAGGAGCGGAAGGAACTACGGCGAATGCTACTGGTAGCAGGCTCAGCAGCATCAGGAAACAATCACAGAGATGATGTCACAGCTTCCATGACTAGCCTTAAGTCTTCTGCCACTGGACACTGTCTCAAGATTTATCGCACATTTCGAGATGAAGAGGGGAAAGAGTATGTTCGCTGTGAGACAGTCCGAAAACCAGCTGTCATTGATGCCTATGTGCGCATACGGACTACAAAAGATGAGAAATTCATTCAAAAATTTGCCCTTTTTGATGAAAAACATCGGGAAGAGATGCGGAAAGAACGGCGGAGGATTCAAGAGCAACTGAGGCGGCTTAAGCGGAACCAGGAAAAGGAGAAGCTTAAGGGTCCTCCTGAGAAGAAGCCCAAGAAAATGAAAGAGCGTCCTGACCTAAAACTGAAATGTGGGGCATGTGGTGCCATTGGACATATGAGGACTAACAAATTCTGCCCCCTCTATTATCAAACAAATGTGCCACCTTCGAAACCTGTTGCCATGACAGAAGAGCAGGAGGAGGAGTTGGAAAAGACAGTCATTCATAATGATAATGAAGAACTTATCAAGGTTGAAGGGACCAAAATTGTCTTCGGGAAACAGCTAATTGAGAATGTGCATGAGGTTCGCAGAAAATCTCTGGTTCTCAAGTTTCCTAAACAGCAGCTTCCTCCAAAGAAGAAACGGCGAGTTGGAACCACTGTTCATTGTGACTATTTGAATATACCTCATAAGTCCATCCACCGACGCCGCACAGACCCTATGGTGACGCTGTCATCCATCCTGGAGTCTATCATCAATGACATGAGAGATCTTCCAAATACACACCCTTTCCACACTCCAGTCAATGCAAAGGTTGTAAAGGACTACTACAAAATCATCACTCGGCCAATGGACCTACAAACACTCCGTGAAAATGTGCGTAAATGCCTCTACCCATCTCGGGAAGAGTTCAGAGAGCATCTGGAGCTAATTGTGAAAAACAGTGCGACCTACAATGGGCCAAAACATTCATTGACTCAGATCTCTCAATCCATGCTGGATCTCTGTGATGAAAAACTTAAAGAGAAAGAAGACAAATTAGCTCGCTTAGAGAAAGCTATCAACCCCTTGCTGGATGATGATGACCAAGTGGCATTTTCTTTCATTCTGGACAACATTGTCACCCAGAAAATGATGGCAGTTCCAGATTCTTGGCCATTTCATCACCCAGTTAATAAGAAGTTTGTTCCAGATTATTACAAAATGATTGTCAATCCAGTGGATTTAGAGACCATACGTAAGAACATCTCCAAGCACAAGTATCAGAGTCGGGAGAGTTTTCTAGATGATGTAAACCTTATTCTTGCCAACAGTGTTAAGTATAATGGACCTGAGAGTCAGTACACTAAGACTGCTCAGGAGATTGTGAACATCTGTTACCAGACAATTACTGAGTATGATGAGCATTTGACTCAACTTGAGAAGGATATTTGTACAGCTAAAGAAGCAGCTTTGGAGGAAGCAGAATTAGAAAGCCTGGACCCAATGACCCCAGGGCCCTACACATCTCAGCCTCCTGATATGTATGATACCAACACATCCCTCAGTACGTCTCGAGATGCCTCTGTATTTCAAGATGAGAGCAATTTGTCTGTCTTGGATATTTCCACTGCCACTCCAGAAAAACAGATGTGCCAGGGCCAAGGTAGGCTGGGTGAGGAAGACTCTCATTGATTGCAAGTTGATGCCTCCTCCACCTCCACCCCCGGGACCAATGAAGAAGGATAAGGACCAAGATGCTATTACCTGTGTGTCTGAAAGTGGAGAAGACATCATCTTGCCCTCCATCATTGCCCCTTCCTTTTTGGCCTCAGAGAAAGTGGATTTCAGTAGTTACTCTGATTCAGAATCTGAGATGGGACCTCAGGAAGCAACACAGGCAGAATCTGAGGATGGAAAGCTGACCCTTCCATTGGCTGGGATTATGCAGCATGATGCCACCAAGCTGTTGCCAAGTGTCACCGAACTTTTTCCAGAATTTCGACCTGGAAAAGTGTTACGCTTCCTACATCTTTTTGGACCAGGGAAGAATGTCCCATCTGTTTGGCGGAGTGCTCGGAGAAAGAGGAAGAAGCATCGTGAGCTGATACAGGAAGAGCAGATCCAGGAGGTGGAATGCTCAGTAGAATCAGAAGTCAGCCAGAAGTCTTTGTGGAACTATGACTATGCTCCACCACCACCCCCAGAGCAGTGTCTCGCTGATGATGAAATCACGATGATGGTTCCTGTGGAGTCCAAATTTTCCCAATCAACTGGAGATGTAGATAAAGTGACAGATACCAAACCAAGAGTGGCTGAGTGGCGTTATGGGCCTGCCCGACTGTGGTATGATATGCTGGGTGTCTCCGAAGATGGCAGTGGGTTTGACTATGGCTTCAAACTGAGAAAGACACAACATGAACCTGTGATAAAATCTAGAATGATGGAGGAATTTAGGAAACTTGAGGAAAGCAATGGCACTGATCTTCTGGCTGACGAAAACTTCCTGATGGTGACACAGCTGCATTGGGAGGATTCTATCATCTGGGATGGGGAGGATATCAAACACAAAGGGACAAAACCTCAGGGTGCAAGCCTGGCAGGCTGGCTTCCTTCTATTAAGACTAGGAATGTAATGGCTTACAATGTTCAGCAAGGTTTTGCACCCACTCTGGATGATGACAAACCTTGGTACTCCATTTTTCCCATTGACAATGAGGATCTGGTGTATGGACGCTGGGAGGACAATATCATTTGGGATGCTCAGGCCATGCCCCGGCTGTTGGAACCTCCTGTTTTGGCACTTGATCCCAATGATGAGAACCTCATTTTGGAAATTCCTGATGAGAAGGAAGAGGCCACCTCTAACTCCCCCTCCAAGGAGAGTAAGAAGGAATCATCTCTGAAGAAGAGTCGAATTCTCTTGGGCAAAACAGGTGTCATCAGGGAGGAACCACAGCAGAACATGTCTCAGCCAGAAGTGAAAGATCCATGGAATCTCTCCAATGATGAGTATTATTTCCCCAAGCAACAGGGTCTTCGGGGCACCTTTGGAGGGAATATTATCCAGCATTCAATTCCTGCTATGGAATTATGGCAGCCCTTCTTTCCCACCCACATGGGGCCCATCAAAATCCGGCAGTTCCATCGCCCACCTCTGAAAAAGTACTCATTTGGTGCACTCTCTCAGCCAGGTCCCCATTCAGTCCAACCTTTGCTAAAGCACATCAAAAAAAAGGCCAAGATGAGAGAACAAGAGAGGCAAGCCTCAGGTGGTGGAGAGTTGTTTTTTATGCGCACACCTCAGGATCTCACAGGCAAAGATGGAGATCTTATTCTTGCAGAATATAGTGAGGAAAATGGACCCTTAATGATGCAGGTTGGCATGGCAACCAAGATAAAGAACTATTATAAACGGAAACCTGGCAAAGATCCTGGAGCACCAGATTGTAAATATGGGGAAACTGTTTACTGCCATACATCTCCTTTCTTGGGCTCTCTCCATCCTGGCCAATTACTGCAGGCACTTGAGAACAACCTTTTTCGTGCTCCAGTGTATCTTCATAAGATGCCAGAAACTGATTTTCTGATCATTCGGACAAGACAGGGTTACTATATTCGGGAATTAGTGGATATTTTTGTGGTTGGCCAGCAGTGTCCCTTGTTTGAAGTTCCTGGGCCTAACTCCAGAAGGGCCAATATGCATATTCGAGACTTTCTACAGGTTTTTATTTACCGCCTTTTCTGGAAGAGTAAAGATCGGCCACGGAGGATACGAATGGAAGATATAAAAAAAGCCTTTCCTTCCCATTCAGAAAGCAGCATCCGGAAGAGGCTAAAGCTCTGCGCTGACTTCAAACGCACAGGGATGGATTCAAACTGGTGGGTGCTTAAGTCTGATTTTCGTTTACCAACGGAAGAAGAGATCAGAGCTAAGGTGTCACCAGAGCAGTGCTGTGCTTATTATAGCATGATAGCTGCAAAGCAACGACTGAAGGATGCTGGCTATGGTGAGAAATCCTTTTTTGCCCCATTTCCGGTTTATGCGACCCGGCTGCGATTTGCTGCTGAGGGCAGCAGCTACCGTCACTGCCGCCATCATGTCAGACTCGGACAGCGAGGAAGATTCATCTGGAGGTGGCCCATTTACTTTAGCGGGTATCCTTTTCGGCAACATCAGTGGAGCGGGGCAGCTGGAGGGGGAAAGCGTCTTGGATGATGAGTGTAAGAAGCACTTGGCAGGCTTGGGGGCTTTGGGGCTGGGCAGCCTAATCACTGAACTCACGGCAAATGAAGAATTGACTGGGACTGGCGGTGCCTTGGTAAATGATGAAGGGTGGATTAGGAGTACAGAAGATGCTGTAGACTATTCAGACATCAATGAGGTGGCAGAAGATGAAAGCCAAAGACACCAGCAGACGATGGGGAGCTTGCAGCCCCTTTACCACTCGg
>XM_005262295.1
TTTCCGGTCTATGGGACCCGGCTGCGATTTGCTGCTGCGGACAGCAGCTACCATCACTGCTGCCGCCATCATGTCAGACACGGACAGCGACGAAGATTCCGCTGGAGGCGGCCCATTTTCTTTAGCGGGTTTCCTTTTCGGCAACATCAATGGAGCCGGGCAGCTGGAGGGGGAAAGCGTCTTGGATGATGAATGTAAGAAGCACTTGGCAGGCTTGGGGGCTTTGGGGCTGGGCAGCCTGATCACTGAACTCACGGCAAATGAAGAATTGACCGGGACTGACGGTGCCTTGGTAAATGATGAAGGGTGGGTTAGGAGTACAGAAGATGCTGTGGACTATTCAGACATCAATGAGGTGGCAGAAGATGAAAGCCGAAGATACCAGCAGACGATGGGGAGCTTGCAGCCCCTTTGCCACTCAGattatgatgaagatgactatgatgctgattgtgaagaCATTGATTGCAAGTTGATGCCTCCTCCACCTCCACCCCCGGGACCAATGAAGAAGGATAAGGACCAGGATTCTATTACTGGTGTGTCTGAAAATGGAGAAGGCATCATCTTGCCCTCCATCATTGCCCCTTCCTCTTTGGCCTCAGAGAAAGTGGACTTCAGTAGTTCCTCTGACTCAGAATCTGAGATGGGACCTCAGGAAGCAACACAGGCAGAATCTGAAGATGGAAAGCTGACCCTTCCATTGGCTGGGATTATGCAGCATGATGCCACCAAGCTGTTGCCAAGTGTCACAGAACTTTTTCCAGAATTTCGACCTGGAAAGGTGTTACGTTTTCTACGTCTTTTTGGACCAGGGAAGAATGTCCCATCTGTTTGGCGGAGTGCTCGGAGAAAGAGGAAGAAGAAGCACCGTGAGCTGATACAGGAAGAGCAGATCCAGGAGGTGGAGTGCTCAGTAGAATCAGAAGTCAGCCAGAAGTCTTTGTGGAACTACGACTACGCTCCACCACCACCTCCAGAGCAGTGTCTCTCTGATGATGAAATCACGATGATGGCTCCTGTGGAGTCCAAATTTTCCCAATCAACTGGAGATATAGATAAAGTGACAGATACCAAACCAAGAGTGGCTGAGTGGCGTTATGGGCCTGCCCGACTGTGGTATGATATGCTGGGTGTCCCTGAAGATGGCAGTGGGTTTGACTATGGCTTCAAACTGAGAAAGACAGAACATGAACCTGTGATAAAATCTAGAATGATAGAGGAATTTAGGAAACTTGAGGAAAACAATGGCACTGATCTTCTGGCTGATGAAAACTTCCTGATGGTGACACAGCTGCATTGGGAGGATGATATCATCTGGGATGGGGAGGATGTCAAACACAAAGGGACAAAACCTCAGCGTGCAAGCCTGGCAGGCTGGCTTCCTTCTAGCATGACTAGGAATGCGATGGCTTACAATGTTCAGCAAGGTTTTGCAGCCACTCTTGATGATGACAAACCTTGGTACTCCATTTTTCCCATTGACAATGAGGATCTGGTATATGGACGCTGGGAGGACAATATCATTTGGGATGCTCAGGCCATGCCCCGGCTGTTGGAACCTCCTGTTTTGACACTTGATCCCAATGATGAGAACCTCATTTTGGAAATTCCTGATGAGAAGGAAGAGGCCACCTCTAACTCCCCCTCCAAGGAGAGTAAGAAGGAATCATCTCTGAAGAAGAGTCGAATTCTCTTAGGGAAAACAGGAGTCATCAAGGAGGAACCACAGCAGAACATGTCTCAGCCAGAAGTGAAAGATCCATGGAATCTCTCCAATGATGAGTATTATTATCCCAAGCAACAGGGTCTTCGAGGCACCTTTGGAGGGAATATTATCCAGCATTCAATTCCTGCTGTGGAATTACGGCAGCCCTTCTTTCCCACCCACATGGGGCCCATCAAACTCCGGCAGTTCCATCGCCCACCTCTGAAAAAGTACTCATTTGGTGCACTTTCTCAGCCAGGTCCCCACTCAGTCCAACCTTTGCTAAAGCACATCAAAAAAAAGGCCAAGATGAGAGAACAAGAGAGGCAAGCTTCAGGTGGTGGAGAGATGTTTTTTATGCGCACACCTCAGGACCTCACAGGCAAAGATGGTGATCTTATTCTTGCAGAATATAGTGAGGAAAATGGACCCTTAATGATGCAGGTTGGCATGGCAACCAAGATAAAGAACTATTATAAACGGAAACCTGGAAAAGATCCTGGAGCACCAGATTGTAAATATGGGGAAACTGTTTACTGCCATACATCTCCTTTCCTGGGTTCTCTCCATCCTGGCCAATTGCTGCAAGCATTTGAGAACAACCTTTTTCGTGCTCCAATTTATCTTCATAAGATGCCAGAAACTGATTTCTTGATCATTCGGACAAGACAGGGTTACTATATTCGGGAATTAGTGGATATTTTTGTGGTTGGCCAGCAGTGTCCCTTGTTTGAAGTTCCTGGGCCTAACTCCAAAAGGGCCAATACGCATATTCGAGACTTTCTACAGGTTTTTATTTACCGCCTTTTCTGGAAAAGTAAAGATCGGCCACGGAGGATACGAATGGAAGATATAAAAAAAGCCTTTCCTTCCCATTCAGAAAGCAGCATCCGGAAGAGGCTAAAGCTCTGCGCTGACTTCAAACGCACAGGGATGGACTCAAACTGGTGGGTGCTTAAGTCTGATTTTCGTTTACCAACGGAAGAAGAGATCAGAGCTATGGTGTCACCAGAGCAGTGCTGTGCTTATTATAGCATGATAGCTGCAGAGCAACGACTGAAGGATGCTGGCTATGGTGAGAAATCCTTTTTTGCTCCAGAAGAAGAAAATGAGGAAGATTTCCAGATGAAGATTGATGATGAAGTTCGCACTGCCCCTTGGAACACCACAAGGGCCTTCATTGCTGCCATGAAGGGCAAGTGTCTGCTAGAGGTGACTGGGGTGGCAGATCCCACGGGGTGTGGTGAAGGATTCTCCTATGTGAAGATTCCAAACAAACCAACACAGCAGAAGGATGATAAAGAACCGCAGCCAGTGAAGAAGACAGTGACAGGAACAGATGCAGACCTTCGTCGCCTTTCCCTGAAAAATGCCAAGCAACTTCTACGTAAATTTGGTGTGCCTGAGGAAGAGATTAAAAAGTTGTCCCGCTGGGAAGTGATTGATGTGGTGCGCACAATGTCAACAGAACAGGCTCGTTCTGGAGAGGGGCCCATGAGTAAATTTGCCCGTGGATCAAGGTTTTCTGTGGCTGAGCATCAAGAGCGTTACAAAGAGGAATGTCAGCGCATCTTTGACCTACAGAACAAGGTTCTGTCATCAACTGAAGTCTTATCAACTGACACAGACAGCAGCTCAGCTGAAGATAGTGACTTTGAAGAAATGGGAAAGAACATTGAGAACATGTTGCAGAACAAGAAAACCAGCTCTCAGCTTTCACGTGAACGGGAGGAACAGGAGCGGAAGGAACTACAGCGAATGCTACTGGCAGCAGGCTCAGCAGCATCCGGAAACAATCACAGAGATGATGACACAGCTTCCGTGACTAGCCTTAACTCTTCTGCCACTGGACGCTGTCTCAAGATTTATCGCACGTTTCGAGATGAAGAGGGGAAAGAGTATGTTCGCTGTGAGACAGTCCGAAAACCAGCTGTCATTGATGCCTATGTGCGCATACGGACTACAAAAGATGAGGAATTCATTCGAAAATTTGCCCTTTTTGATGAACAACATCGGGAAGAGATGCGAAAAGAACGGCGGAGGATTCAAGAGCAACTGAGGCGGCTTAAGAGGAACCAGGAAAAGGAGAAGCTTAAGGGTCCTCCTGAGAAGAAGCCCAAGAAAATGAAGGAGCGTCCTGACCTAAAACTGAAATGTGGGGCATGTGGTGCCATTGGACACATGAGGACTAACAAATTCTGCCCCCTCTATTATCAAACAAATGCGCCACCTTCCAACCCTGTTGCCATGACAGAAGAACAGGAGGAGGAGTTGGAAAAGACAGTCATTCATAATGATAATGAAGAACTTATCAAGGTTGAAGGGACCAAAATTGTCTTGGGGAAACAGCTAATTGAGAGTGCGGATGAGGTTCGCAGAAAATCTCTGGTTCTCAAGTTTCCTAAACAGCAGCTTCCTCCAAAGAAGAAACGGCGAGTTGGAACCACTGTTCACTGTGACTATTTGAATAGACCTCATAAGTCCATCCACCGGCGCCGCACAGACCCTATGGTGACGCTGTCGTCCATCTTGGAGTCTATCATCAATGACATGAGAGATCTTCCAAATACATACCCTTTCCACACTCCAGTCAATGCAAAGGTTGTAAAGGACTACTACAAAATCATCACTCGGCCAATGGACCTACAAACACTCCGCGAAAACGTGCGTAAACGCCTCTACCCATCTCGGGAAGAGTTCAGAGAGCATCTGGAGCTAATTGTGAAAAATAGTGCAACCTACAATGGGCCAAAACACTCATTGACTCAGATCTCTCAATCCATGCTGGATCTCTGTGATGAAAAACTCAAAGAGAAAGAAGACAAATTAGCTCGCTTAGAGAAAGCTATCAACCCCTTGCTGGATGATGATGACCAAGTGGCGTTTTCTTTCATTCTGGACAACATTGTCACCCAGAAAATGATGGCAGTTCCAGATTCTTGGCCATTTCATCACCCAGTTAATAAGAAATTTGTTCCAGATTATTACAAAGTGATTGTCAATCCAATGGATTTAGAGACCATACGTAAGAACATCTCCAAGCACAAGTATCAGAGTCGGGAGAGCTTTCTGGATGATGTAAACCTTATTCTGGCCAACAGTGTTAAGTATAATGGACCTGAGAGTCAGTATACTAAGACTGCCCAGGAGATTGTGAACGTCTGTTACCAGACATTGACTGAGTATGATGAACATTTGACTCAACTTGAGAAGGATATTTGTACTGCTAAAGAAGCAGCTTTGGAGGAAGCAGAATTAGAAAGCCTGGACCCAATGACCCCAGGGCCCTACACGCCTCAGCCTCCTGATTTGTATGATACCAACACATCCCTCAGTATGTCTCGAGATGCCTCTGTATTTCAAGATGAGAGCAATATGTCTGTCTTGGATATTCCCAGTGCCACTCCAGAAAAGCAGGTAACACAGATGCGCCAGGGCCGAGGTAGGCTGGGCGAGGAAGACTCTGATGTAGATATTGAAGGGTATGATGATGAGGAGGAGGATGGGAAACCTAAGACTCCAGCCCCAgaaggtgaagatggagatggtgatcttgcagatgaagaggaagGAACTGTACAACAGCCTCAAGCCAGTGTCCTGTATGAGGATTTGCTTATGTCTGAAGGAGAAGATGATGAGGAAGATGCTGGGAGTGATGAAGAAGGAGACAATCCTTTCTCTGCTATCCAGCTGAGTGAAAGTGGAAGTGACTCTGATGTGGGATCTGGTGGAATAAGACCCAAACAACCCCGCATGCTTCAGGAGAACACAAGGATGGACATGGAAAATGAAGAAAGCATGATGTCCTATGAGGGAGACGGTGGGGAGGCTTCCCATGGTTTGGAGGATAGCAACATCAGTTATGGGAGCTATGAGGAGCCTGATCCCAAGTCGAACACCCAAGACACAAGCTTCAGCAGCATCGGTGGGTATGAGGTATCAgaggaggaagaagatgaggaggaggaagagcagCGCTCTGGGCCGAGCGTACTAAGCCAGGTCCACCTGTCAGAGGACGAGGAGGACAGTGAGGATTTCCACTCCATTGCTGGGGACAGTGACTTGGACTCTGATGAATGAGGCTTCCTTTGGGCCTCCTTGGTCAGCCTTCCCTGTTCTCCAGCCTAGGTGGTTCACCTTTCCCCAATTTGTTCATATTTGTACAGTATCTGATCCTGAAATCATGAAATTAACTAACACCTTAGCCTTTTTAAAAGTAGTAAGTAAATGATAATAAATCACCTCTCCTAATCTTCCTGGGGCAATGTCACCCTTTGATTTAAAACAAAGCAACCCCCTTTCCCCTACCACTACGGAAAAGAGCAAGCTCATTTTTCCGTGTCCTCCTTTATTTAACTCCATTTATTGCTTTTGGTATAATTTTTCCCTGGGGAAGGAGGGGAAATTATGAAAGAACTAGTAACTTTATGTCCTCTTGATGTATTAGGAAATTTCCggccaggcgtggtggctcacacctgtaatctcagcactctgggaggccgaggcgggcagatcacctgaggtcagaagttcgagaccagcttggccaacatggcgaaaccgcatctctactaaaaatacaaaaattagccaggtgtggtggcgtatgcctgttaatcctagctactcgggaggctgaggcaggagaattacttgaacccgggaggcagaggttgcagtgagtggaggtcacgccactgcactccagcctgggcgaaagagtgagattcagtctcaaaaaaaaaaaaaTTTCCAAGCATGGTATCATCTCACTTTTCTAATTTACAGGCTGGAGCAGATGAGAGCCCTCCTGCTGGGACAGAGAATTGGGTTCTAGTGGACTCTGTGCTACACTTAAACCTGTGAGACAAACCGCCCATTATTTTATTATTTAATTATGCAATGCCTAGTTCCTAAATGGATTGGAGGCAAATTACCGTAAATTTTGAAACAGCCTATATGTCAGAAATGATAATGTTGCCACCTAAATGTTTTCTGTCCCCCCCACCCTCCCCAGGGGAAATGGTAGGAAAATGgtaagtttcttagggcaaagactgtgtcttctgtttcttttcatgcttaggatatggttctgtgcatagtaggtactcagtaaatgttcctagaatCATAAAATCCtcaacagatatgttactgagcatctgcttttcatgataagcactctatcagatccttgggatgcaaaggtaaataagacaaatcccttttacccaaagagctcaccatcaagttgggggagggaaagtggaattcaaaacatgttaataaatcatcatagtactgtgagataagtgcaattaagaagctagttataaagtataggggaaatagaggagtaatcatgtctgaaaagtcaggaaagtcttcctagaggtaatttttaagctgattgttttagaattagtagaagcttgccagatggaaaagtccaggcaaagtgtaacatgaatgggaaaggcCACAGTCTAGAAATGGCAGAGTGTGTTCCTAGTTTGTTTGtttgtttgtttgtacctgccttgttccaggaaggatttaatgtggtttataTTCCAGTCCTTTAATGCTGGAAGGGCTGAGATGAGACTGAAAGATGGGCAGGAAGTATATCATCACAAGCTTTGTGTTTGATGTTAATGTGTATGATTTTTATATTATGGGAAATAAGCTCTTAGAGGAGTGATATAATCAGGTTTGTGTTTTAGAAATCTGTGTAATGAAtgaatgaagaaagaaattgaagaatcatgtaacatatgtgatcgcatttttgtaaaagaaccatgtgtgtttatatgtgtttatatatatacttgtgtatgcaaaggtaaaagtctgaaaggatatatgctaactgttcacaatgataaccccccaggaatgggattggaggggagggggcttctgtgtttgttatgtatgctgggtgggatattgtgcttttatttctatattgtttgaatttttttacagtatgtattatttttgtaataaaaattttaaaaAATTCCA

Publications

PMID - Link Title
36736316Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.
36215168TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing.
35384245Physical and functional interactome atlas of human receptor tyrosine kinases.
35271311OpenCell: Endogenous tagging for the cartography of human cellular organization.
35140242Human transcription factor protein interaction networks.
32174793TAF1L promotes development of oral squamous cell carcinoma via decreasing autophagy-dependent apoptosis.
31527615The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.
30804502H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.
30585729Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.
29568061An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.
29511261Insights into the ubiquitin-proteasome system of human embryonic stem cells.
27571988Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.
24755198A meta-analysis of somatic mutations from next generation sequencing of 241 melanomas: a road map for the study of genes with potential clinical relevance.
24007313Whole transcriptome sequencing identifies tumor-specific mutations in human oral squamous cell carcinoma.
22939629A census of human soluble protein complexes.
22658931A genome-wide association study of host genetic determinants of the antibody response to Anthrax Vaccine Adsorbed.
22658674Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
22464331Histone recognition and large-scale structural analysis of the human bromodomain family.
21873635Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
17643375Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.
15489334The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
12477932Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
12217962Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis.