Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ATP5F1AP10
Plot displaying the genomic locations of a retrocopy (in chr9) and its respective parental gene (in chr18). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr9:66721434-66722864  UCSC
Coordinates (T2T) chr9:78490792-78492222  UCSC
Coordinates (hg19) chr9:41799116-41800545  UCSC
Strand +
Parental Sequence NM_001001935.3
Parental seq. overlap 1326 bp
Parental seq. overlap (%) 22.7%
Genomic Region Intergenic
Retrocopy Summary ATP5F1AP10, located on chr9:66721434-66722864, is a retrocopy of the parental gene ATP5F1A. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ATP5F1A
Full Name ATP synthase F1 subunit alpha
Also known as ATP5A|ATP5A1|ATP5AL2|ATPM|COXPD22|HEL-S-123m|MC5DN4|MOM2|OMR|ORM|hATP1
Coordinate chr18:46080248-46104227
Strand -
Gene summary This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the alpha subunit of the catalytic core. Alternatively spliced transcript variants encoding the different isoforms have been identified. Pseudogenes of this gene are located on chromosomes 9, 2, and 16. [provided by RefSeq, Mar 2012]

Homology

Species Scientific Name Retrocopy
Bonobo Pan paniscus ATP5F1AP2
Orangutan Pongo abelii ATP5F1AP2
Green monkey Chlorocebus sabaeus ATP5A1P3
Rhesus Macaca mulatta ATP5F1AP3
Chimpanzee Pan troglodytes Without Homology
Gorilla Gorilla gorilla Without Homology
Gibbon Nomascus leucogenys Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ATP5F1AP10
aAACCTGACAATGTTGGTGTTGTCGTGTTTGGAAATGTTTAACTAATTAAGGAAGGAGCTAGAATGAAGAGGACAAGAGCCATTGTGGACATTCCAGTTGGTGAGGAGCTGTTGGGTCATGTGGTTGATGCCCTTCGTAATGCCATTGATGGAAAGGGTCCATTTGGTTCCAAGAACCATAGGTGAGTTGGTCTGAAAGCCCCTGGAATCATTCCTCAAATTTCAGTGCAGGAACCAATGCAGACTGGCATTAAGGCTGTAAATAGCTTGGTGCCAATTGGCCATGGTCAGTGTGAGCTGATTATTGGTAATGGACAGACTGGAAAAATCTCAATTGCTATTGACACAATCATTAACCAGAAATGTTTCAATGATGGATCTGATGAAAAGAAGAAGCTGTACTGTGTCTATGTTGTTATTGGTCAAAAGAGATCCACTGTTGCCCAGTTGGTGAAGAGACTTACGATGCAGATGCCATGAATTACACCATCGTGGTGTCAGCTACGGCCTCAGATGCTGCCCCACTTCAGTAACTGGCTCCTTACACTGGCTGTTCCATGGGAGAGTATTTTAGAGACAATGGCAAACATGCTTTGACCATCTATGACAACTTATCCAAACAGGCTGTTGCTTACCATCAGATGTTTCTGTTGCTCTGCCAACCCCCTGGTTGTGAGGCCTATCCTGGTGTTGTGTTCTACCTATGCTCCCAGTTGCTGGAGAGAGCAGCCCAGATGAACAATGCTTTTGGTGGTGGCTCCTTGACTGCTTTGCCAGTCATAGAAACAGACTGGTGATGTGTCTGCTTACATTCCAATGAATGTCATTTCTATCACGAACGGACAGATCTTCTTGGAAACAGAATTGTTCTACAAAGGTATCCACCCTGCCATTAATGTCGGTCTGTCTGTGTCTCGTGTCAGATCTGCTGCCCAAACCAGGGCTATGAAGCAGGTGGCAGGTACCATGAAGCTGGAAGTGGCTCAGTATCATGAGGTCACCACTTTTGCCCAGTTCAGTTCTGACCTCGATGCTGCCACTCAACAACTTTTGAGTTGTGGTGTGTGTCTAACTGAGTTGCTGAAGCAAAGACAGTATACTCCCATGGCTATTGAAGAACAAGTGGCTGTTATCCATGTGGGTATTAGGGGCTATCTTGATAAACGGGAGCCCAGCAAGATTACAAAGTTTGAGAATGCTTTCTTGTCTCATGTCAGCTGACACCAAGCCCTGTTGGGCACTACCAGGGCTGATGGAAAGATCTCAGAAGAATCAGATGCTGAATTTGAAGCTTAAACGCCTGTGGATTTACATCAAATACCAGTTCAGTTTTGTCATTGTTTATTCTAGTAGATTAGTTTCATTTGTGAAAGGGTTACTCTCATACTCCTTATGTACAGAAATCACATGAAAAGTAAAGGTTCCATAATG
>NM_001001935.3
CATTTTGTCCCAGTCAGTCCGGAGGCTGCGGCTGCAGAAGTACCGCCTGCGGAGTAACTGCAAAGATGCTGTCCGTGCGCGTTGCTGCGGCCGTGGTCCGCGCCCTTCCTCGGCGGGCCGGACTGGTCTCCAGAAATGCTTTGGGTTCATCTTTCATTGCTGCAAGGAACTTCCATGCCTCTAACACTCATCTTCAAAAGACTGGTAAGTTATTATTTCTCAGTCTACGCCGCACTTACTAGATGAAGATATAAATTACATACATCGTATAACTGTGGGACTGCTGAGATGTCCTCTATTCTTGAAGAGCGTATTCTTGGAGCTGATACCTCTGTTGATCTTGAAGAAACTGGGCGTGTCTTAAGTATTGGTGATGGTATTGCCCGCGTACATGGGCTGAGGAATGTTCAAGCAGAAGAAATGGTAGAGTTTTCTTCAGGCTTAAAGGGTATGTCCTTGAACTTGGAACCTGACAATGTTGGTGTTGTCGTGTTTGGAAATGATAAACTAATTAAGGAAGGAGATATAGTGAAGAGGACAGGAGCCATTGTGGACGTTCCAGTTGGTGAGGAGCTGTTGGGTCGTGTAGTTGATGCCCTTGGTAATGCTATTGATGGAAAGGGTCCAATTGGTTCCAAGACGCGTAGGCGAGTTGGTCTGAAAGCCCCCGGTATCATTCCTCGAATTTCAGTGCGGGAACCAATGCAGACTGGCATTAAGGCTGTGGATAGCTTGGTGCCAATTGGTCGTGGTCAGCGTGAACTGATTATTGGTGACCGACAGACTGGGAAAACCTCAATTGCTATTGACACAATCATTAACCAGAAACGTTTCAATGATGGATCTGATGAAAAGAAGAAGCTGTACTGTATTTATGTTGCTATTGGTCAAAAGAGATCCACTGTTGCCCAGTTGGTGAAGAGACTTACAGATGCAGATGCCATGAAGTACACCATTGTGGTGTCGGCTACGGCCTCGGATGCTGCCCCACTTCAGTACCTGGCTCCTTACTCTGGCTGTTCCATGGGAGAGTATTTTAGAGACAATGGCAAACATGCTTTGATCATCTATGACGACTTATCCAAACAGGCTGTTGCTTACCGTCAGATGTCTCTGTTGCTCCGCCGACCCCCTGGTCGTGAGGCCTATCCTGGTGATGTGTTCTACCTACACTCCCGGTTGCTGGAGAGAGCAGCCAAAATGAACGATGCTTTTGGTGGTGGCTCCTTGACTGCTTTGCCAgtcatagaaacacaggctggtgatgtgtctgcttacattccaacaaatgtcatttccatcactgacggacagATCTTCTTGGAAACAGAATTGTTCTACAAAGGTATCCGCCCTGCAATTAACGTTGGTCTGTCTGTATCTCGTGTCGGATCCGCTGCCCAAACCAGGGCTATGAAGCAGGTAGCAGGTACCATGAAGCTGGAATTGGCTCAGTATCGTGAGGTTGCTGCTTTTGCCCAGTTCGGTTCTGACCTCGATGCTGCCACTCAACAACTTTTGAGTCGTGGCGTGCGTCTAACTGAGTTGCTGAAGCAAGGACAGTATTCTCCCATGGCTATTGAAGAACAAGTGGCTGTTATCTATGCGGGTGTAAGGGGATATCTTGATAAACTGGAGCCCAGCAAGATTACAAAGTTTGAGAATGCTTTCTTGTCTCATGTCGTCAGCCAGCACCAAGCCTTGTTGGGCACTATCAGGGCTGATGGAAAGATCTCAGAACAATCAGATGCAAAGCTGAAAGAGATTGTAACAAATTTCTTGGCTGGATTTGAAGCTTAAACTCCTGTGGATTCACATCAAATACCAGTTCAGTTTTGTCATTGTTCTAGTAAATTAGTTCCATTTGTAAAAGGGTTACTCTCATACTCCTTATGTACAGAAATCACATGAAAAATAAAGGTTCCATAATGCATAGTTGTTTTCTGTCATTTGTGTTATTCTTTAAAACCAAGATCAAATTGAGAAATTGGTAAGCAAATGCTTCTTGATCTATTTTACTTGAATATTGGTACAGTCAACTGGGCTAGATAATTCAAGGCTGAGCTCTTTGTAAGttttttttttgtttttttttttgagactgattctcactctgtcactgaggctggagtgcagtggcaccctgtcggcccactgcaacctccgtctccgggttcaagcaattctcttgcctcagcctcccacgtagctgggattacaggtgcccaccaccacgcctggctagttttttagtatttttagtagagacggggtttcaccatgttggccaggccggtcacgaactcctgacctcaggtgatccacctgccttggcctacctaccacagtgctgggattacaggtgtgagccaccgcacccggcTGCTCTTTGTAAGTTTCTAGAGTACTTTGTGTTTAAGAGAAATTCCTAAACTGGATATATGTGGCAGGCTGACAATACTGAAGAGCATAGCTGGCTTCTCTGCCCAGAGGATGTACCTGCATAAAGAGGTACTGTAGGCAGGAAAATAATAGGACAGTTAAAATTCTCAGGGAAATGAAAAAATTGCTGGAACAAAAGCTGAGAAGATAGAATGCATAGGATTATGAAAACTTGTCAATATCTCttttgtttgttttgtgacagggtctccatctctctcacccaggctggagtacagtggtgtgatctcagctcactgcagcttctgccacctgggttcaattgattcttccacctcagcctcctgagtagctggggttacaggcacataccaccacgcccagccaatttttctactttttgtagagggagggtcttgccatgttgtccaggctgatgatgaactccttggctcaagtgatcctcctgccttggtctcccaaagtgctgggattacaggtgtgaactaccatgcccggccATCTTTTAATATTTTCACAGCTACTTTATTTCCTCTGTTACTAGCTTTTCATAGCCTTTGCTCATTCTTACTGCATTAAAttttttttactgatttatttatttttttgagacagagtcttgctctgtcacctaggctggagagcagtggcgtaatctcagctcactgcacctttcacctcctgggttcaagcgattctcctgccttagcctcccaattagctgggaccacaggcccatgccaccacacccggctaacattttgtatttttagtagagacaaggtttcaccatgttggccatgctgctcttgagctcctgacctcgtggtctgcccgcctcagcttcccaaagtgctgggattacaggtgtgagccaccacgcccagccTACTGATTTATTTATTTACTTTTAATTTTTCATAGCCTTTGCTCATTCTTAATGTGTTACCtttttttttacttagttatttatttatttgagatggagtctccgtcgtccaggctggagtgcagtgacctgatcttggctcactgcaacctctgcctccaggttcaagcaattctcctgcctcagcctcccgagaagctggaactacaggcacccaccaccatgccctgctaatttttgtatttttagtagaggcggggtttcaccatattggccaggctggtctcgaactcctgaccttgtgatctgcctgccttggcctcccacagtgctgggattacaggtgtgagccaccacacctggccttttttttttttttttgagacggagtctcactgtctcccaggctggagtgcagtggtgcgatgtcggctcactgcaagctctgccccctgggtttgcgccgttctcctgcctcagcctcccgattagctggtactacaggcgcctgccatcacgcccagctaatttttttttttttgtatttttagtagagacggggtttcaccatgttcgccaggatggtctcgatctcctgacctcatgatccacttacctcggcctcccaaagtgctgggattacaggcttgagccaccgcgcccggccTCttttttttttttttttttttACTGATATATAAAGGCTTTTGTCTGTAAGGGTCATACATGGTCATGTTCTAAAATATTTTTCCTAGGGTTCCCCCTTCCTTGCCATTTTATTTTGTTGATGGGGATTTGCTGTACCGAAACTTCATTCTTATCCATCTCTCTGTCTCCAGTAAGTCAAAATATATTTACATATGTGGGCTCCAATATCTTTGGTAGGAAAAGGAGAGTTCTTAAAGTACTCATAAGTCCTTTTCAGTACTTAGAGGAACACTAAACTTGATAGCAGTTGGTCATTTCTGATCAACTCTTGCTTTCTAGCTACTTGAGAAATAACTTCTAGATCTGATTTTCCTTTTCTGAAATAAGGAAGTTACTTTTAGTTAGAAGGTTCTGCACATTTCGttttttttttttttttttttttttgttttttttttttgagagttttgctcttgttgcccaggctggagtgcaatggcacgatctcggctcaccacaaccaccgcctcctggggtcaagcaattctcctgcctcaggctcctgagtagctgggattacaggcatgcaccaccacgcctggctaattttgtatttttagtagagatggggtttctccatgttggtcaggctggtctcaaactcctgaccttaggtggtccaccggcctcccaaagtactgggattacaggggtgagccactgcgcccggcTTGTTGGAGCATTTTatacctagtgtcagtggtgattactactttggagaaaaataCTTTGGCTAATGGATTGGAATTAATTTATTACTGGGAGTATGTATTGTTTGTTTGTTGACTGGATCTCGTAGCCCACTCCTGGCACGTAAATGCTCAATAAACTTCTCAAATGAAGACAACCATGTTTGTCCATTATAAATCAAATTCCAAATGTTAACTACTGGTCTGGTCTGATGAGAtttttttttttttttttttttttgagacggagttttgtttttgttgcccaggctggagtgcaatggcgcgatctcggctcactgcaacctccacctcctgggttcaagtgattctcctacctcagcctcctgagtagctgtgattataggtgtgcaccaccatgcctggctaatttttgtatttttagtagagacggggtttcaccatgttggccaggctggtttcgaactcctgaccttagatgatccacgtgcctcgacctcctaaagtgctgggattacaggcgtgagccactgtgcctggccCACGCCAGGCACAGTGATATTTAAAAATGTGATTTTTAAATATCACATTTAAAAATATGTGATATTTTTAAAGAATATGATAGCccaggcgcagtggcttacgcctgtaatctcagcactttgggacgatcacttgagcccaggagtttgaaacaggctgcagtcagctatgatcacgccactgcactccagcctaggtgacagagaccctgactcttaaaaaaaGTTGTGCTAGAAGACTTCAAGATCTCCCCTAAAACTGTATAGTCCTTTCCCTGGTGTTTTTGCTGAGCTATAGAGTCCAGCCCTTTCTGTTACAGCAATGAACCATGAGATTCAAATACTGCTTTTTACTAAGTACTTACAGACTAATGACATAGGAGACCTCATAGGCACCTGGCTGTTTTTAACCAGGCAGGCCTAAATACACTGCCCAAGTGGCCCTTCTGTGTGGCAACAAAATGGCTGTCATAAAATTGTGTCTGTGTGCATTTATCTTATCACTGGGGGTGGTGAACATTTGAGAAGGCACTTGACCTTTGAAATGTGAAGTTTTATGGATTTCAGACTTGTATTTTAAAAACTATTTGTTAACTGTAA

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