Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name AGAP1P14
Plot displaying the genomic locations of a retrocopy (in chr9) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr9:73648905-73649434  UCSC
Coordinates (T2T) chr9:85800298-85800827  UCSC
Coordinates (hg19) chr9:76263821-76264350  UCSC
Strand +
Parental Sequence XM_024452679.1
Parental seq. overlap 482 bp
Parental seq. overlap (%) 20.2%
Genomic Region Intergenic
Retrocopy Summary AGAP1P14, located on chr9:73648905-73649434, is a retrocopy of the parental gene AGAP1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name AGAP1
Full Name ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
Also known as AGAP-1|CENTG2|GGAP1|cnt-g2
Coordinate chr2:235494043-236131795
Strand +
Gene summary This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes LOC738814P1
Bonobo Pan paniscus AGAP11P1
Gorilla Gorilla gorilla LOC101143406P1
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>AGAP1P14
TATCAGCCAGACAAGTAATGGAGGTGGGAGTTTAAGTGACTATTCCTCCTCCATTCCATCGACTCCCAGCATCAGCCAGGAGGAACTTCGGATCGATGTTCCTCCCACTTCCAACACACCCACGCCCGTTCGCAAGCAGTCCAAGCGCTGGTCCAACCTGTTTACCTCTCAGAAAGGGAGCAACCCAGACAAAGAGAAGAAGGGCCTGGAGAATCGTGCAGACAGCATCAGGAGGGGCAGAGCCATCCCCATTAAACAGGGCATGCTATTCAAGCTAAGTGGCAAAGGGCTGAAGAAATGGAAAAAGAAATATGTCACCCCATGTGACAACGGCGTGCTGACCTACCATCCAAATTTACATGATTACATGAAGAATATTCATGGTAAAGAGATTGACCTTGGGAGAACCACTGTGAAAGTCCCAGGGAAGAGGCCACTGCTAGCCACATCTGCCTGTGCGCGCATCTCCAGCTCTAAAACCAATGGCCTAACCAAGGACATGAGCAGTTTACACATCTCACCCAATTCAG
>XM_024452679.1
TcccggcccgcctgccctccccgcttggcccggcgccctcccggcccgcgggctcgcTGGATGCGGCGGGGCCCCAGCGCGCGGGCGACATGTACTTGTTGGACGGCAGTGGCGAGCCCGCGTCGCCACCCGCGGACGCGATGCCGCGCGGGACGCCCCCCAGAAAGACTGTCTACCGCATCTCCGTGACCATGGTCAGGAAGGAGCAGCTggccgcgccgggctccggcggcccggacccacgcccggttcggcggccccggcccgcgcgctccccggacgcgcccggGAGGCTTgaggaggaggccgaggaggcggagggcgccgaggaaccggaggGTCCCCGGCCGCGCGCTTGGGATTTCCGCACCTTCCGCACCCGCAGCACCGGGCAGCTGGAACTGGGGCGGCTCCGGCCGTGCGCACGCGGCCTGGAACCCGCGGACCTGGCCGGCAGCGCCCCGGCCGAGGAGGAGGGACGCGGCTCGCCCGCGTCCGGCAGCCCCGACGTGGAGGGGGCCCGGGCCGCGCCCCTGCGGCGGAGCCTGAGCTTCAGGCACTGGAGCGGGCCTGAGGCGCCGCAAGGCCGGACACTGGGCGGCGGAAGGCGCCACAGCAGCTCCGGGAGCCTGGCCTGGGCGCCGTGCGACGAGGCCGCGGCCGGGACCACCCTGGAGCCCGCGACCGCCACGCAGCCCGCCTCGGAGAAGCGCAACACCCTGGACGTGGGCGAGGTGCTCAGCAAGAACGACGCGCTCTCGGACCTGGAGCGTTGGGAACGCAGTAAGAGCAAGAACCGCACGCTGGACAACAGCGACCTGCAGCGGCTGGAGCGCGCGCGGGCGGCGGCCGGGGCCGGCGCGGCCTCGGAGCACCGGCTGCTGCGCTTCTTCAGCGGCATCTTCGCGCGCAGGGACGGGGGCCCGGGCGGCGGGCCCTCGCCACGGAGCGGAGCCTCGCGGCCACGCGGCTACTTCAGCCTGCGGCGGGCCCCGGCCGAAGCGCACTCGTCCAGCGCCGAGAGCATCGACGGCTCCCCGCGCAGAGATGCCTTCGTGAACAGCCAGGAATGGACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGTGGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGACGGGCACATATGTCCAGGAGGAGTCTCCGGAAGATATGGATGCAGGTGGCAGGTTCAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAGAGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGTGGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCAGACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAGTTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTACATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCAGAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTGCAAGTCGCTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTCCGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGGGAGTTTAAGCGACTATTCCTCCTCCGTTCCATCGACTCCCAGCACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACACGCCCACGCCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCTGTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCTGGAGAGTCGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCCAATTAAACAGGGCATGCTGTTGAAGCGAAGTGGCAAATCGTTGAATAAAGAGTGGAAAAAGAAATATGTCACCCTGTGTGACAATGGCGTGCTGACCTATCATCCCAGTTTACATGATTACATGCAGAATGTTCATGGTAAGGAGATTGACCTTCTGAGAACCACTGTGAAAGTCCCAGGGAAGAGGCCACCCCGAGCCACGTCAGCCTGCGCACCCATCTCCAGCCCTAAAACCAATGGCCTATCCAAGGACATGAGCAGTTTACACATCTCACCCAATTCAGtttttcttggctactgctgcctgcttatttttcctcaaatgaactaaagagtaacttgAAACCTTCTCCTCCTTGATAAAAAtaatcccctcattggtgcacatgacatcaggacctcccgaggctgtgatacgggcacgtAAATAAAATAAtaaaaataattc

Publications

PMID - Link Title