Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name DDX10P2
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Plot displaying the genomic locations of a retrocopy (in chr9) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr9:82085648-82088840  UCSC
Coordinates (T2T) chr9:94235277-94238469  UCSC
Coordinates (hg19) chr9:84700563-84703755  UCSC
Strand -
Parental Sequence NM_004398.4
Parental seq. overlap 1720 bp
Parental seq. overlap (%) 38.1%
Genomic Region Intergenic
Retrocopy Summary DDX10P2, located on chr9:82085648-82088840, is a retrocopy of the parental gene DDX10. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name DDX10
Full Name DEAD-box helicase 10
Also known as Dbp4|HRH-J8
Coordinate chr11:108665069-108940927
Strand +
Gene summary DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it may be involved in ribosome assembly. Fusion of this gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients with de novo or therapy-related myeloid malignancies. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes DDX10P1
Bonobo Pan paniscus DDX10P1
Gorilla Gorilla gorilla DDX10P1
Orangutan Pongo abelii DDX10P1
Green monkey Chlorocebus sabaeus DDX10P1
Crab-eating macaque Macaca fascicularis DDX10P1
Rhesus Macaca mulatta DDX10P1
Baboon Papio anubis DDX10P1
Golden snub-nosed monkey Rhinopithecus roxellana DDX10P1
Gibbon Nomascus leucogenys Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Related Sequence

>DDX10P2
GATTTGATCCAAGCACACTCCTAGATCCAGATAAGTACAGAAGCTCTGAAGATTCAGATAGTGAAGATATGGAAAATAAAATGTGATACCAAGAAGAAGCAGGGAATGAAAAAGAGGAAGAACAGTGAAGTGGAAGATGTAGGACCAACAAGTCATAACAGAAAGAAGGCCACGTGGGACACTTTAGAGCCTTTGGATACTGGCCTGTCTTTAGCAGAGGATGAAGAGCTGGTGTTACATCTGCTAAGAAGTTAAAGCTAAATACTTCCTGCGCCTGCCTTCTCCTTGAAACCTTGGTTATGATTGTGTAGACAAGATGCTGAAAAACAATTGATTTGGGGGCACTTAGGTACCATATGTCCCATTCCCAAAGGGCACATTTCTGGATAGAAGCAATTGTATTTCCAAGTCCCTCTCACAGGGCATGCTTTGTGCCATCACTGAGCATACTCAGATCGAGGATAGATGATACTATTTCCTGACCCCATTTTCCAGCATGTGTTCTGTTAGATTTTTATCCATGGGTTCCTAAGCCTTGTCATTGGAAATGCTTCCTTTGTTTTACTGGCAAGTTCTGGAGCTCTTGTGTCATTGTTAGAAATTCCTGTCTCGCTTACTGTACAGAAGTTTCTATGTTACTGTTAAAATTGCTCATGATTTTGATGTATTTAATATTTGCAAAGAGACTGAGTATGATGGACCAGCCCTGAGAAAGAATGAGTATTTTTGAATTGAGATGATCAATAATAAACATATTTCCTATTTCTCAAGCTCCATCTCTTCCTAACACCAGTGAAGCAAAGAAGATCAAGGAAGTTCCTATGCAGTTCCTGGACAGAGATGAGGAGGAAGAAGATGCTGATTTCTTGAAGGTGAAGTGGCACAATGTGTTTGGATTTGACTTTAAAGAGGAGAAAACATTACAGAAGAAAGAACCTTCTAAATCCAGCATCAAGAAAAAAGTGACCAAAGTTGCAGAAGCAAAAAAAGTAATGAAGAGAAATTTTAAAGCGAATAAGAAGATAACATGTACTGATGAAGGGGAGTTGGTTCAACAGTGGCCACAAATGCAGAAATCTGCCATCAAGGATGCTGAGGAAGATGATGACACGGGTGGTATCAACTTAGATAAAGCAAAGGGAAGACTTCAGAAAGAGGACAAATTTGACAAAGAAGAATATAGGAAGAAAATTAAGGCAAAGCATTGGGAGAAAAGACTGAAAGAAAGGGAAGCCAGAAGAGAAGCCAACACGAGACAAGCAAAGGCCAAAGATGAAGAGGAAGACTTTCTGGATTGGAGCATGTTGGTTCCATGAGCCTGGCCTTAGGTGTCTCGTGTCTGGGGGTGATCCCAGCTGTCGCTGCCGCCGCAATGGGCAAAACTGCGGACTCTCCGGGTTCGGGAGCCCGACCCGACCCGGTGCGGAGCTTCAATCGCTGGAAGAAAAAACACAGCCACGGGCAGAACAAAAAGAATCAGTTGAGGAAGCAACTGAAGAAACCCGAATGGCAGGTCGAGCGCGAGGGTAACAGCCGCCTCATGCAGAACTATGAGAAGATAAATGTAAATGAAATTACAAGATTTTCAGATTTTTCCTTGTCCAAAAAAACATTGAAAGGTTTGCAAGAAGCTCAGTACCGTTTGGTAACTGAGATACAGAAGCAGACCATTGGATTGGCTTTGCAAGGTAGAGATGTACCTGGAGTGGCCAAAACTGGATCTGGCAAGACTTTGGCTTTCCTTGTTCCAGTGCTAGAAGCCTTATATCGTCTGCAATAGACCTCAACAGATGGGCTGGGGGTTCTCATAATATCACCTATGAGAGAACTGACCTATCAGACCTTTGAGGTTCTCCAAAAGGTAGGAAAGAATCATGACTTCTCAGCTGGTCTCATCATTGGTGGAAAGTATCTGAAACACGAAGCTGAGAGGATCAACAACATAAATATACTCGTGTGCGCACCAGGTCGGCTTCTTCAACACATGGATGAAACGGTGTCTTTTCATGCTACTGCTCTCCTAATGTTAGTTCTTGATGAAGCATATAGAATCTTGGATGTGGGCTTTGCTGATACCATGAATGCTATTATTGAAAATCTCCCCAAGAAACGTCAGACTTTACTTTTCTCAGCAACACAAACTATATCTGTAAAGGACCTTGCACGCTTGAGTTTGAAAAACACTGAGTATGTCTGGGTTCATGAAAAATGCAAAATATAGCACCCCTGCCACTTTGGAACAGAACTACATAGTCTGTGAGCAGCAGCAAAAAATAAGTGTGCTGTATTCCTTTTTGAGAAGGCACCTGAAGAAGAAGAGCATTGTATTTTTTTCCAGTTGCTAAAAGGTCTGATATCTGTACCGAGTGTTTTGCCAGCTACGTCCTGGTATTTCTATCCTTGCCCTCCATGGTCGATAGCAGCAAATGAGAAGAATGGAAGTCTATAATGAGTTTGTCCGTAAGAGAGCTGCAGTACTCTTTGCTAGTGATGTTGCAGCCAGGGGGCTGGATTTCCCGGCTGTGAATTGGGCTCTTCAGTTTGATTGTCCTGAGGATGCCAACACATATATTCACAGAGCAGGTAGAACTGCCAGGTACAAAGAGGATGGTGAAGCTTTATTAATTTTGCTTGCCTCAGAAAAAGCTATAGTGCAGCAGCTTCTTCAGAAGAAAGTACCTATAAAGGAAATCAAAATCAATCCAGAAAAACTTATAGATATCCAGAAAAAATTGGAATCTTTTTCAGCTGAAGATCAAGATTTAAAAGAAAGAGCTCAAAGGTGTTTCATCTCCGATATATGATTGGTATATCTGATGAAGGATAAAGAAGTATTTGATGTGAGCAAGTTACCTATACCTGAATATGCCCTGTCTCTTGGGCTTGCTGTGGCACCATGCATAAGATTTCTTCAGAAAATGCAGAAACAACCCACCAAAGAATTGGTAATGAGCCAAGCCAATAAAGTAACTGAGCCAAGGGCTCCCTCCCTCACCAATGACAAAGTGGAAGAATTTAGAGCCTTCTTCAATGAGAAAATGTCCATCCTTCAGAAAGGTGGAAAAAGACTCAAAGGGACAGAGCACAGACTGGCTAATGATACTAGTg
>NM_004398.4
GCGTTTGTCCCATGCTGGTTCCGTGAGTCTGGCCTTAGGTGTCTCGTGTCTGGGGTTGATCCGAGCTGTCGCCGCCGCCGCCGCAATGGGCAAAACGGCCAACTCTCCGGGTTCGGGAGCCCGACCCGACCCGGTGCGGAGCTTCAATCGCTGGAAGAAAAAACACAGCCATAGGCAGAACAAAAAGAAGCAGTTGAGGAAGCAACTGAAGAAACCCGAATGGCAGGTCGAGCGCGAGAGTATCAGCCGCCTCATGCAGAACTATGAAAAGATAAATGTAAATGAAATCACAAGATTTTCAGATTTTCCCTTGTCCAAAAAAACATTGAAAGGTTTGCAAGAAGCTCAGTACCGTTTGGTGACTGAGATACAGAAGCAGACCATTGGATTGGCTTTGCAAGGTAAAGATGTACTTGGAGCGGCCAAAACTGGATCTGGCAAGACTCTGGCTTTTCTTGTTCCAGTGCTGGAAGCCTTATATCGTCTGCAATGGACTTCAACAGATGGGCTGGGGGTTCTCATAATATCACCTACGAGAGAACTGGCCTATCAGACCTTTGAGGTTCTCCGAAAAGTAGGAAAGAATCATGACTTCTCAGCTGGTCTCATCATTGGTGGAAAGGATCTAAAACACGAAGCTGAGAGGATCAACAACATAAATATACTCGTGTGCACACCAGGTCGGCTTCTTCAACACATGGATGAAACAGTATCTTTTCATGCTACCGACCTCCAAATGTTAGTTCTTGATGAAGCAGATAGAATCTTGGATATGGGCTTTGCTGATACCATGAATGCTGTTATTGAAAATCTCCCCAAGAAACGTCAGACTTTACTTTTCTCAGCAACACAAACTAAATCTGTAAAGGACCTTGCACGCTTGAGTTTGAAAAACCCTGAGTATGTCTGGGTTCATGAAAAAGCAAAATATAGCACCCCTGCCACTTTGGAACAGAACTACATAGTCTGTGAGCTGCAGCAAAAAATAAGTGTGCTGTATTCCTTTTTGAGAAGCCATCTGAAGAAGAAGAGCATTGTATTTTTTTCCAGTTGCAAAGAGGTCCAGTATCTGTACCGAGTGTTTTGCCGGCTACGTCCTGGTGTTTCTATCCTTGCACTCCATGGTCGACAGCAGCAAATGAGAAGAATGGAAGTCTATAATGAGTTTGTCCGTAAGAGAGCTGCAGTACTCTTTGCTACTGATATTGCAGCCAGGGGTCTGGATTTCCCGGCCGTGAATTGGGTTCTTCAGTTTGATTGTCCTGAGGATGCCAACACATATATTCACAGAGCAGGTAGAACTGCCAGGTACAAAGAGGATGGTGAAGCTTTGCTAATTTTGCTACCCTCAGAAAAAGCTATGGTGCAGCAGCTTCTTCAGAAGAAAGTACCTGTGAAGGAAATCAAAATCAATCCAGAAAAACTTATAGATGTCCAGAAAAAATTGGAATCTATTTTAGCTCAAGATCAAGATTTAAAAGAAAGAGCTCAAAGGTGTTTCGTCTCCTATGTACGATCTGTATATCTGATGAAGGATAAAGAAGTATTTGATGTGAGCAAGTTACCTATACCTGAATATGCCCTGTCTCTTGGTCTTGCTGTGGCACCACGCGTAAGATTTCTTCAGAAAATGCAGAAACAACCCACCAAAGAATTGGTAAGGAGCCAAGCCGATAAAGTAATTGAGCCAAGGGCTCCCTCCCTCACCAATGACGAAGTGGAAGAATTTAGAGCCTACTTCAATGAGAAAATGTCCATCCTTCAAAAAGGTGGAAAAAGACTCGAAGGGACAGAGCACAGACAGGATAATGATACTGGTAATgaagaacaggaagaagaagaagacgatgaagaagaaatggaagagaaACTGGCAAAAGCAAAAGGATCTCAAGCCCCATCTCTTCCTAACACCAGTGAGGCACAGAAGATCAAGGAAGTTCCTACACAGTTCTTGGACAGAGATGAGGAGGAAGAAGATGCTGATTTCTTGAAGGTGAAGCGGCATAATGTGTTTGGATTGGACCTTAAAGACGAGAAAACATTACAGAAGAAAGAACCTTCTAAATCCAGCATCAAGAAAAAAATGACCAAAGTTGCAGAAGCAAAAAAAGTAATGAAGAGAAATTTTAAAGTGAATAAGAAGATAACATTTACTGATGAAGGGGAGTTGGTTCAGCAGTGGCCACAAATGCAGAAATCTGCCATCAAGGATGCTGAGGAAGATGATGACACAGGTGGTATCAACTTACATAAAGCAAAGGAAAGACTTCAGGAAGAGGACAAATTTGACAAAGAAGAATATAGGAAAAAAATTAAGGCAAAGCATCGGGAGAAAAGACTGAAAGAAAGGGAAGCCAGAAGAGAAGCCAACAAGAGACAAGCAAAGGCCAAAGATGAAGAGGAAGCCTTTCTGGATTGGAGtgatgatgatgatgatgatgatgatgGATTTGATCCAAGCACACTCCCAGATCCAGATAAATACAGAAGCTCTGAAGATTCAGATAGTGAAGATATGGAAAATAAAATAAGTGATACCAAGAAGAAGCAGGGGATGAAGAAGAGGAGCAACAGTGAAGTGGAAGACGTGGGACCAACAAGTCATAACAGAAAGAAGGCCAGGTGGGACACTTTAGAGCCTTTGGATACCGGCCTGTCTTTAGCAGAGGATGAAGAGCTGGTGTTACATCTGCTAAGAAGTCAAAGCTAAATACTTCCTGCGCCTGCCTTCTCCTTGAAACCTTGGTTATGACTGCGTAGGCAAGAAGTTGAAAAACAGTTGATTTGGGGGCACTTAGGTACCATATGCCCCATTCCCAAAGGGCACATTTCTGGATAGAAGCGATCGTATCTCCAAGTCCCTCTCACAGGACATGCTTTGTGCCATCACTGAGCATACTCAGATCGAGGGTGGATGATACCATTTCCTGACCCCGTTTTCCAGCATGTGTTCTGTTAGATTTTTATCCATGGGTTCCTACGCCTTGTCATTGGAAACACTGCCTTTGTCTTACTGGCAAGTTCTGGAGCTCTTGTGTCATTGTTAGAAATCCCTGTCTTGCTTACTGTACAGAAGTTTCTGTTGCTGTTAAAATTGCTCATGATTTCGACGTATTTAATATTTTCAAAGAGACTATGATGGACCAGCCCTGAGAAAGAATGAGTATTTTTGAATTGAGATGATCAATAATAAACATATTTCCTATAAAAGAAA

Publications

PMID - Link Title
No publications available for this retrocopy