Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name FBP2P1
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Plot displaying the genomic locations of a retrocopy (in chr9) and its respective parental gene (in chr4). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr9:87816475-87818095  UCSC
Coordinates (T2T) chr9:99969861-99971481  UCSC
Coordinates (hg19) chr9:90431390-90433010  UCSC
Strand +
Parental Sequence NM_001276459.3
Parental seq. overlap 1388 bp
Parental seq. overlap (%) 41.5%
Genomic Region Intergenic
Retrocopy Summary FBP2P1, located on chr9:87816475-87818095, is a retrocopy of the parental gene ELF2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ELF2
Full Name E74 like ETS transcription factor 2
Also known as EU32|NERF|NERF-1A|NERF-1B|NERF-1a,b|NERF-2
Coordinate chr4:139057220-139177218
Strand -
Gene summary Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transcription, DNA-templated; positive regulation of transcription, DNA-templated; and regulation of transcription by RNA polymerase II. Located in cytosol and nuclear body. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ELF2P3
Bonobo Pan paniscus ELF2P3
Gibbon Nomascus leucogenys ELF2P1
Golden snub-nosed monkey Rhinopithecus roxellana ELF2P3
Marmoset Callithrix jacchus ELF2P1
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Adipose SubcutaneousMuscle SkeletalArtery TibialArtery CoronaryHeart Atrial AppendageAdipose VisceralUterusVaginaBreast Mammary TissueSkin Not Sun ExposedMinor Salivary GlandBrain CortexAdrenal GlandThyroidLungSpleenPancreasEsophagus MuscularisEsophagus MucosaEsophagus Gastroesophageal JunctionStomachColon SigmoidSmall Intestine Terminal IleumColon TransverseProstateTestisNerve TibialSkin Sun ExposedHeart Left VentricleBrain CerebellumWhole BloodArtery AortaPituitaryBrain Frontal CortexBrain CaudateBrain Nucleus AccumbensBrain PutamenBrain HypothalamusBrain Spinal CordBrain HippocampusBrain Anterior Cingulate CortexOvaryBrain Cerebellar HemisphereLiverBrain Substantia NigraKidney CortexBrain AmygdalaCervix EctocervixFallopian TubeCervix EndocervixBladderKidney Medulla00.10.20.30.4
log10(TPM+1)

Related Sequence

>FBP2P1
gAGAATTGAAGCTACTGAAGCCCTGCTTCCTATGAAATCTCCCACCTACTTGAGGGATTCAAGAAGTCCTGAATTTATCCATGTTGCTATGAGGCCAGATATCATTACAGAAACTGTAGTGGAGGTGTCAACTGAGGGGTCTGAACCAACGGATACCTCTCCTATTCCTACATCACCAGATAGCCATGAACCAATGAAAAGGAAAAAAATTGGCTGTAAACCAAAGACCCAACAATCACCAATTTCCAGTGGGTCTCCTGAGTCAGGTATAAAAAAAAAGATGAGAGAAGGAAAAGGAAACATAATATATTTGTGGGAGTTTCTTTTAGATCTACTTAAAGATAAAAATATTTGTCCCCTCTATATTAAATGGATTCAGAGAGAAAAAGGCATATTCAGGCTGGTGGATTCAAAGGCTGTCTCCAAGTTTTGGGGAAAGCATAAGAACAAACCAAACATGAACTATGAAACTATGGAATGAGCTTTGAGATTCTATTACCAAAGGGGAATTATTGCAAAGCTACCAAAAGGGAAGTCTTGCAAAGGTTGAAGGACAGAGGCTTGTATATCAGTTTAAGGATATGCCCAAAACCATAGTGGTCACAGATGATGACAGAAGTGAAATCTGTAATGAAAATTTAGCAGGAGCTACTGATAAAAAATCATTGGAACGAGTGTCACTGTCGGCAGAAAGTCTCCTGAAAGCAGCATCCTCTGTTTGTGATAGAAAAAATTCATCCCCCATAAACTTCTCCAGAGCAGAGAAGAGTGTAGCTAGAGTCGTGAATATCACTTCCCCTGGTCACGATGCTTCATGCAGGTTTCCAACTACCACTGCATCTGTATCAGCAACAGCAGCTCCAAGGACAGTTTGTGTGGCAATGCAAGTACCTGTTGTAATGACATCATTGGGTCAGAACATTTCAACTGTGGCAGTTCAGTCAGTTAATGCAGGTGCACCATTAATAACCAGCACTAATCCAACAACAGCGACCTCTCCAAAGGTAGTCATTCAGATAATCCCTACTATGATGACAGCTTCTACTGAAAACCAAGAAAAAATCACCATGCAGCCTGTCAAAATTATTACCATCCCAGCTACACAGTTTGACTTTGTCAACTACAGACAAAGTCAAATTTAACTGGATCAGGAAGCATTGACATTGTTGGAACACCATTGGCTGTGAGAGCACTTACCCTTGTTTGTTTCAATAGCCCATGGTACACCTGTAATGAGACTCTCAGTGCCTACTCAGCAGGCATCTGGCCAGACTCATCCTCTAGTTATCAGTTTGGTCATAAAGGGGCCAGAGGTTAACTCAGAAGCAGTGGCAAGAACACAAGAACATGATGTGAAAACTTTGCAGCTGAAAGAAGAAAAGCCGGCAGATGGAAATGAGACAGTTACCCACGTAGTGGTTGTCAGTGTACCTTCAGCTATTGCCCCTTCTTGTAACTATGAAAATGATGGACTAGTGACATGTGAGAAATAAAATAGCAGCTCCACCATGTGCTTCAGGCTGTTAGTGGTAGTAGTGACATAAACATTTGCAAGGGAAGTCATCAAGAAAAGCCAAAGAGGACTTTAAGACATTTTTAATGCTTATAAGAAAACAAT
>NM_001276459.3
AATGTGAAGCAGCAGCTCCAGCCCCGGGATAAACATGGCGACGTCTCTGCATGAGGGACCCACGAACCAGCTGGATCTGCTCATCCGGGCCGTGGAAGCATCAGTTCACAGCAGTAATGCACACTGTACAGATAAGACAATTGAAGCTGCTGAAGCCCTGCTTCATATGGAATCTCCTACCTGCTTGAGGGATTCAAGAAGTCCTGAATTCATCCATGCTGCTATGAGGCCAGATGTCATTACAGAAACTGTAGTGGAGGTGTCAACTGAAGAGTCTGAACCCATGGATACCTCTCCTATTCCAACATCACCAGATAGCCATGAACCAATGAAAAAGAAAAAAGGAAACACAACCTATTTGTGGGAGTTTCTTTTAGATCTACTTCAAGATAAAAATACTTGTCCCAGGTATATTAAATGGACTCAGAGAGAAAAAGGCATATTCAAGCTGGTGGATTCAAAGGCTGTCTCTAAGCTTTGGGGAAAGCATAAGAACAAACCAGACATGAACTATGAAACCATGGGACGAGCTTTGAGATACTACTACCAAAGGGGAATTCTTGCAAAGGTTGAAGGACAGAGGCTTGTATATCAGTTCAAGGATATGCCGAAAAACATAGTGGTCATAGATGATGACAAAAGTGAAACCTGTAATGAAGATTTAGCAGGAACTACTGATGAAAAATCATTAGAACGAGTGTCACTGTCTGCAGAAAGTCTCCTGAAAGCAGCATCCTCTGTTCGCAGTGGAAAAAATTCATCCCCTATAAACTGCTCCAGAGCAGAGAAGGGTGTAGCTAGAGTTGTGAATATCACTTCCCCTGGGCACGATGCTTCATCCAGGTCTCCTACTACCACTGCATCTGTGTCAGCAACAGCAGCTCCAAGGACAGTTCGTGTGGCAATGCAGGTACCTGTTGTAATGACATCATTGGGTCAGAAAATTTCAACTGTGGCAGTTCAGTCAGTTAATGCAGGTGCACCATTAATAACCAGCACTAGTCCAACAACAGCGACCTCTCCAAAGGTAGTCATTCAGACAATCCCTACTGTGATGCCAGCTTCTACTGAAAATGGAGACAAAATCACCATGCAGCCTGCCAAAATTATTACCATCCCAGCTACACAGCTTGCACAGTGTCAACTGCAGACAAAGTCAAATCTGACTGGATCAGGAAGCATTAACATTGTTGGAACCCCATTGGCTGTGAGAGCACTTACCCCTGTTTCAATAGCCCATGGTACACCTGTAATGAGACTATCAATGCCTACTCAGCAGGCATCTGGCCAGACTCCTCCTCGAGTTATCAGTGCAGTCATAAAGGGGCCAGAGGTTAAATCGGAAGCAGTGGCAAAAAAGCAAGAACATGATGTGAAAACTTTGCAGCTAGTAGAAGAAAAACCAGCAGATGGAAATAAGACAGTGACCCACGTAGTGGTTGTCAGTGCGCCTTCAGCTATTGCCCTTCCTGTAACTATGAAAACAGAAGGACTAGTGACATGTGAGAAATAAAATAGCAGCTCCACCATGGACTTCAGGCTGTTAGTGGCAGTACTGACATAAACATTTGCAAGGGAAGTCATCAAGAAAAGTCAAAGAAGACTTTAAAACATTTTTAATGCATATACAAAAACAATCAGACTTACTGGAAATAAATTACCTATCCCATGTTTCAGTGGGAAATGAACTACATATTGAGATGCTGACAGAAAACTGCCTCTTACAGTAGGAAACAACTGAACCCATCAATAAGAAAAAGGATCGAAAGGGACCAAGCAGCTCACTACGATATCAAGTTACACTAAGACTTGGAACACTAACATTCTGTAAGAGGTTATATAGTTTTCAGTGGGAGGGGTTGGGATGGGTAATCTCATTGTTACATATAGCAATTTTTGATGCATTTTATATGCATACCAGCAATTATTACTGTGTTCGCACAGTTCTCACTTAACTGGTGCTATGTGAAGACTCTGCTAATATAGGTATTTTAGAATGTGAATTGAAGAATGGATCCCAAAAACTTCAGAAAGAGGATAGCAAAAAAAGATCTAGTGCGATTTtatatatatatatatatatatatacatacatatatatatatcatataGCTTAAGCTGATTTAAAACAAAGGCCTTAGACTAATTTTCGATTTTCTTTCTTGAAATAAGCTAATGGCTTGTTTGTGTAAAGCTTTTTTATTAAAAGAAAAATTTTAAAAATCTTGTACCTAGCACAGTATTGTTATAGAATATACATGTAACATTTTATATGGTAGTTTAAGTCTGTCAGTTTCTTAATTGTGGACAAATTAACAGTTGGCTCTGGCCTTTTGCTGTAACATGCCTGTGTCACTCACTTAGCCTTGGCATTTGTGCAGACATACCATTTTCAGTTCTGCTGTCACTTGGAAGTTCAGGCTCAGCATGAATTTTTGGCAGGTAGCTCTAATACCTGGAGttttctttgtttttttttcttttttttAGTTGAAGTTTATGAGGGAAATACCAGTGTTCAGTTTTGAACTATAATAGTTTGTATATTCAACATTTGAAGTATATTCTATTTTGTTGTACTCTTGTTTCAAAGTGTATTCAAGTAGGTTTTCTGAAATATAGAAATGAAATTTATCTTCTGTTTTGGTCTCTGGTGATATTTTAAACAATATTTAAAAGTCAGTATAGAAGTGTTTTAGTTAGGAAGTGATAAAACATCTCTCTTCTCCTTCCCAACTACTGCATGAAGAAATTCTACTTCCATTATATTAATATTTGGCAAATATCTGCATGTTGCCAGTTTCTTTCTAATTATGATGAACTATAATGTTCTGCTTAACGTAATGAATTTAGTATTTTAGTTGGCTGCACTTAAAGAAtttatatttgtaaaacactttaaaccatttgtttcacaatcagaccttttgtggattaaaaagaacaattactcttctagcccttttacagattaggaagttaaggtatctgaaggattaCATAAACTATGTAATTTTACTACTGTCTGTCACTCCATATCTTAATGCTCTTTCTACTACAAAGAAAAGTTATCTATTTTTACATGTTTTAGAAATGTAGATGAACTCATACATAATATTTTTTGTCTTTTAATTGATCACATACTACTTAGGTCAGAAATTGTTTATAACAGTTCCCTTTGTAATCTTTTAAACTTTTCCATAAATATATTGATGATACTTTTATACAAAA

Publications

PMID - Link Title
No publications available for this retrocopy