Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name MFN1P2
Plot displaying the genomic locations of a retrocopy (in chr9) and its respective parental gene (in chr3). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr9:88187734-88190047  UCSC
Coordinates (T2T) chr9:100341828-100344141  UCSC
Coordinates (hg19) chr9:90802649-90804962  UCSC
Strand -
Parental Sequence NM_033540.3
Parental seq. overlap 1549 bp
Parental seq. overlap (%) 28.8%
Genomic Region Intergenic
Retrocopy Summary MFN1P2, located on chr9:88187734-88190047, is a retrocopy of the parental gene MFN1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name MFN1
Full Name mitofusin 1
Also known as hfzo1|hfzo2
Coordinate chr3:179347709-179394936
Strand +
Gene summary The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes MFN1P1
Bonobo Pan paniscus MFN1P1
Gorilla Gorilla gorilla MFN1P1
Orangutan Pongo abelii MFN1P1
Gibbon Nomascus leucogenys LOC115837303P1
Green monkey Chlorocebus sabaeus MFN1P1
Crab-eating macaque Macaca fascicularis MFN1P1
Rhesus Macaca mulatta MFN1P1
Baboon Papio anubis MFN1P1
Golden snub-nosed monkey Rhinopithecus roxellana MFN1P2
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>MFN1P2
TCAGGGAGGTTACCAAGGAAGTGGCAAACAAGGTTTCACGTGCAAAGACAGATGAAATTTGTTGACTGTCTGTTTTGGTTGATGAATTTTATTCAGTTTCATCCTACTCCACGTGTATTGAAAGTATGTAAAGGTGACTTAAATTAGCACTTAGAAGACGGTATCAGAAGAAATATGGCTGATTGATGCACCAATTAAGACAATGCCTCAATGTTTAATCCAAGCAAGAAATTATTAAAAATTTGAAACCATTACTTTCAGCTATATATAGAATAAACTGCATACACTAATCCCTTGCAAGAAATTTGATCTCAGTCATGACCTATATTGCCACAAGTTATGACCAGATTTTCAAGAGGGTATTGTATTCCATTTTTCCCTGGGCTGGTCTTCACTTGTGCATTGATTCCTGGGCCCTACAAATGCTCAGAGGGTGCTCCTAGGATTGTCAGAGCCTAACTTTCCCTAGCTCTTTAGCCTGTACTCCCACTGCTTCTATCAACCCAGCAACACCAGATAATGCATCACACAAAGAACTCATGGTTACCTTAATAACAGGATTAGCTTCTCTTACATCTAGGACTTCTACGGACATCACTGTTGGAGGAGTAATTTGGAAAACTATAGGCTGGCAATTCGTATATGTTTCATTATGTATGTATGGAGTTTGGTATCTTTATGGAAGGCTGTCCTGGACCACTTGTGCCAAGGAAAGAGGCTTTAAACAACAGTTTGTGAACTATGCTTCTGAAAAACTTCAGATAATTGCTAGCTTCAGGAATGCAAACTGCAGCCATGAAGTACAACAAGAAATGGCTATCACTTTCGCTTGCCAGTGCCAACAAGTTGTTACTAAAAGACATCTGGAAGAAATTACTAGATTATCCAAAGAAATAGATCAGTTAGAGAACATACAAAACAATTCAAAACTCTTTAGCAACATATAAGAATCTAGAACTTGACTGAGCTACTGAGGATAATCAAGTAGAAATGTAAGAATATAAAAACAAGCTTTCTATCATTGGTAAGGTGCTATCTCGGAGACAAATGAAGGTGGCATTTTTTGGCAGGACAAGCTCTGTTATCAATGCAATGTTGTGGGATAAAGCTCTCCTTAGTGGGATTGATCATACAACCAATTGCTTCCAAAGTGTTTAAGAGACCAATGGAGATAAAACCTATCTTATGACAAAAGGATAAGATGAAAAAACAGTGTAAACACAGTTCATCAGCTGTCCTATGCCCTTCATGTGGACAAAGGCTTGGAAGCTGGCTGTCTTATACATGTGTTTTGGCCAAAGACAAAGTGTGTCCTCTTGAAAGGTGAGCTGGTTTTAGTAGACAGTCCAGGCACAGATGTCACTACAGAGCTGGATACCTGGATTGATGAGTGTTGCTTAGATGCTTATGTCATCATTTTGTTTGTAAACTCTGAATCAACACTAATGAACACAGAAAAACATTTTTTTCACAAGGTAAATGAGCAGCTTTCCAAGCCTAATAATTTAATTCTGAATAATCACTGGGATGTCGCTTCATCAGAGCCAGAATATATGGAAGATGTATGTAGACAGCACATGGAAAGATGCTTGCATTTCTTTGTGGAGGAGGTTAAAGTTGTGGATCCTTTAGAAGCACAGAATCATATATTCTTCATTTCAGCAAAGGAAGTTCTTAGTGCTAGACAGCACAAACCACAGGGGATGCCAGAAAGCAGTGAAGTACTTGGTAAACGATTTCAGGCAAGATTACAGGAGTTTCAGAATTTTAACAAATCTTTAAGGAGTGTATCTCACAATCAGCAGTGAAAACAGGGTTGAAACAGCACACTATCGGAGCTAAGCCAATACTAGATATTGTGAAAAACACAATGGATTCAATAAACGTGGCAGCAACAGAGAAGAGTTTATTCAAAGAAAGAGCGGGAAGAACAAATCGACAGACTGAGCTTTATCCCAAACCAGATGAACCTTTTAACACTAGATGTTAAGAAAAAAATCAGGAAg
>NM_033540.3
ACTCCCCCTGCCTCCTCTCCGCCTTTAACTTCTCGGGAAGATGAGGCAGTTTGGCATCTGTGGCCGAGTTGCTGTTGCCGGGTGATAGTTGGAGCGGAGACTTAGCATAATGGCAGAACCTGTTTCTCCACTGAAGCACTTTGTGCTGGCTAAGAAGGCGATTACTGCAATCTTTGACCAGTTACTGGAGTTTGTTACTGAAGGATCACATTTTGTTGAAGCAACATATAAGAATCCGGAACTTGATCGAATAGCCACTGAAGATGATCTGGTAGAAATGCAAGGATATAAAGACAAGCTTTCCATCATTGGTGAGGTGCTATCTCGGAGACACATGAAGGTGGCATTTTTTGGCAGGACAAGCAGTGGGAAGAGCTCTGTTATCAATGCAATGTTGTGGGATAAAGTTCTCCCTAGTGGGATTGGCCATATAACCAATTGCTTCCTAAGTGTTGAAGGAACTGATGGAGATAAAGCCTATCTTATGACAGAAGGATCAGATGAAAAAAAGAGTGTGAAGACAGTTAATCAACTGGCCCATGCCCTTCACATGGACAAAGATTTGAAAGCTGGCTGTCTTGTACGTGTGTTTTGGCCAAAAGCAAAATGTGCCCTCTTGAGAGATGACCTGGTGTTAGTAGACAGTCCAGGCACAGATGTCACTACAGAGCTGGATAGCTGGATTGATAAGTTTTGCCTAGATGCTGATGTCTTTGTTTTGGTCGCAAACTCTGAATCAACACTAATGAATACGGAAAAACACTTTTTTCACAAGGTGAATGAGCGGCTTTCCAAGCCTAATATTTTCATTCTCAATAATCGTTGGGATGCCTCTGCATCAGAGCCAGAATATATGGAAGACGTACGCAGACAGCACATGGAAAGATGCCTGCATTTCTTGGTGGAGGAGCTCAAAGTTGTAAATGCTTTAGAAGCACAGAATCGTATCTTCTTTGTTTCAGCAAAGGAAGTTCTTAGTGCTAGAAAGCAAAAAGCACAGGGGATGCCAGAAAGTGGTGTGGCACTTGCTGAAGGATTTCATGCAAGATTACAGGAATTTCAGAATTTTGAACAAATCTTTGAGGAGTGTATCTCGCAGTCAGCAGTGAAAACAAAGTTCGAACAGCACACTATCAGAGCTAAACAGATACTAGCTACTGTGAAAAACATAATGGATTCAGTAAACCTGGCAGCTGAAGATAAAAGGCATTATTCAGTGGAAGAGAGGGAAGACCAAATTGATAGACTGGACTTTATTCGAAACCAGATGAACCTTTTAACACTGGATGTTAAGAAAAAAATCAAGGAGGTTACCGAGGAGGTGGCAAACAAAGTTTCATGTGCAATGACAGATGAAATTTGTCGACTGTCTGTTTTGGTTGATGAATTTTGTTCAGAGTTTCATCCTAATCCAGATGTATTAAAAATATATAAAAGTGAATTAAATAAGCACATAGAGGATGGTATGGGAAGAAATTTGGCTGATCGATGCACCGATGAAGTAAACGCCTTAGTGCTTCAGACCCAGCAAGAAATTATTGAAAATTTGAAGCCATTACTTCCAGCTGGTATACAGGATAAACTACATACACTGATCCCTTGCAAGAAATTTGATCTCAGTTATAATCTAAATTACCACAAGTTATGTTCAGATTTTCAAGAGGATATTGTATTTCGTTTTTCCCTGGGCTGGTCTTCCCTTGTACATCGATTTTTGGGCCCTAGAAATGCTCAAAGGGTGCTCCTAGGATTATCAGAGCCTATCTTTCAGCTCCCTAGATCTTTAGCTTCTACTCCCACTGCTCCTACCACTCCAGCAACGCCAGATAATGCATCACAGGAAGAACTCATGATTACATTAGTAACAGGATTGGCGTCCGTTACATCTAGAACTTCTATGGGCATCATTATTGTTGGAGGAGTGATTTGGAAAACTATAGGCTGGAAACTCCTATCTGTTTCATTAACTATGTATGGAGCTTTGTATCTTTATGAAAGACTGAGCTGGACCACCCATGCCAAGGAGCGAGCCTTTAAACAGCAGTTTGTAAACTATGCAACTGAAAAACTGAGGATGATTGTTAGCTCCACGAGTGCAAACTGCAGTCACCAAGTAAAACAACAAATAGCTACCACTTTTGCTCGCCTGTGCCAACAAGTTGATATTACTCAAAAACAGCTGGAAGAAGAAATTGCTAGATTACCCAAAGAAATAGATCAGTTGGAGAAAATACAAAACAATTCAAAGCTCTTAAGAAATAAAGCTGTTCAACTTGAAAATGAGCTGGAGAATTTTACTAAGCAGTTTCTACCTTCAAGCAATGAAGAATCCTAACAATAGAGATTGCTTTGGTGACCATGATAGGAGGAAACGAAACTTGTAAGATTGGAACAGTTGTTATTTTTATGAAATTACTTTAAATATGAATTGTACTAACTGTACCTAAATAGCAAAGCCCTGTGTAGATTCTGGTAATGATCTGTCTCAGGGTATGTGTATTTTTGAAGAGTGTTATGTCCTTAGTTTTAATTTTGAGTAAAGAAAAGGCTAAAATCATGAATTAGTTACAAGCAACAGTACCAACTTATGTGACCCCTGAGGGGTGGGGCTGTGAGCTCTTAATTTGTTTTTGATTCTGAAAAACTCTGCTTCCTGGCATCCAGGAGTTAGAGATTGAGCCTTTCATCTTCTTTCTCAAAACTAGTTTTTGATGCTTTCTTTCATGGGAATAGTCACTTTTTTATTTAGTAAATCGCATTGCTGGAACCACCAAGGAGTGTGGAATGTCCTTGAGTGTATTATTTATGCAAGTCACAGTCACGTTGCCATCATGGCAGCTATGTGAAACACTAATAAATGTGTTTTTACTTTTTATTCCCGTTAAAACTGATGTAAAACAGGATAAAGGCTTGTTATAGTCACTTATAAGTATCTGGGTCTAAGTAATTTCCTTAGATGTTTCTAAAGAAACATTTTCAGCTTTGCTCCCATTATGATTCCAATAAGGAACGCTTTCCTAGTGCAATTTTAGGAGTAAAGTTTGAAGAGATAAAAATAGCCAAAGATAGGAGACGTCTGAATTTTGAATGATAAACAGTGATGTTTTAAAAAAGCTGTTGTTCTTCAGGAGGCATTTGCCTAGGATATTGCTGGATTATACCCCATTGGAGGCTTTTAATTTTATTTGTATGAATTTTCCAGGATTTCATTAAAAATTATTATTGTATTTTTTACCTTAATGAAAGATTTTGGGTTCAAATATCTTTCTATATTAAAAGCTGATTGAgtctgtacatatgtaaattatgcctagtggaggttctgttgactttcttccccactgtggaagaggccagttttgcctccatttgcacattcatttcagttatttctgatccataaatataacatttacaaaattcttccttgagctggtggaaatgcctcaccagtttcctctttaatgaatcaaataaaatctttaacTGATGTTAAAAAAAATTGATTGAAACTCAGATGGAATGGAAATGTACAAAAATGACACCATTCTAGGAATttgctagacaaaatgtaggactaccagatcagtatctcctagacacttgttagaaatgcacaatcccgggGAACGCAGTACATTTGGCCACATGTAGTTTATGTTTCCTTTTCATGGGAGGGATAAAATTTAAAGCTTTTTTTTTCTTTGAATACAGTCCTTCCTTTTCTATGCCTTTTAAGGCTTCTAGATGCTATTCAGCCTTTTTACAGCAGGTGCAACTCTATTTTTCAAGGTATCTTAGAAGATAACACTAGGCCATTGAAGCCTTTCAAAAATATATTTTTATGCAAATTGACACGAGTGCAGTATACTAATGCAAATTAATTTTGGTGTTTAGCTTTTATTGCTCATTTATAACCCAAGAAATGGTACAGACCACAGTAAGTGGGATTAGGTAACAACTACAACATGGAAAAACAGTGTCTAAGATCACGTACTGCTAATTTAGGTTACAAAACTCAAGGCTGTAACCTTTATATGAAAGTACTTAAGCTTGAAAGTTCATAATAGTTTGGTATCACCTCATTAGTATAGTAcagtggttctcaaagtttggtcctgggtcatcgacattacttctttttctttctgagacagggtctcagtctgtcacccaggatggagtgcagtggcgtgatcatggctcactgcagcctcaacctctcgggttcaggtgatcctcccacatcagcctcctgggtggctgggactacaggcacacgccaccatgcctggctagtttttgtaaagacgaggtttccccatgttgtgcaggctggtcttgaactcacagactcaagtgatccttttacctcagcctcccaaactgttgggataacaggtgtaagccaccacacacagctataatcaaccttcaaacttataaaaagtgtggatccttgggtctgaacccagacctatggagtcagacagtaggtttgaggcccagcaatctatggtttaacaagccatccaggtgtttctgatgcacagtgaaattggggtaccactgGTATTAGGTTTGGTATGGCAACTTTTTCATCACTTGTTTTATGTAGTTGTCTGATCAATTGTGAAAACATAATGAATGTTGGAAATGGAACAGTAAAATAACGAAAGCCAACtttttttttttttttttttttttttgagacggagtctcgctctgtcgcccaggctggagtgcagtggcgcgatctcggctcactgcaagctccgcctcccgggttcacgccattctcctgcctcagcctcccgagtagctgggactacaggcgcccgccaccacgcccggctaattttttgtatttttagtagagacggggtttcaccgtgttagccaggatggtctcgatctcctgacctcgtgatccacccgcctcggcctcccaaagtgctgggattacaggcgtgagccaccgcgcccggccGAAAGCCAACTCTTATGCCTAGAAATATGTGCACCTATGACCAAGCCCATGAATTATACAGGAATTATGTAATTATGAGTGATGTACTTCAAAGTTATTGCACATACACTTGTTTACTTTGTATGTTTGCAGGATTAAACTTTGTATAATCTTTTTACAAAAATTTTTTTTCAGTATGCAAGCTTGCAAGATGAAAATAAAACCTGTTTGCCTGATAGTTGA

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