Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PNRC2P5
Plot displaying the genomic locations of a retrocopy (in chr9) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr9:96918663-96919393  UCSC
Coordinates (T2T) chr9:109090453-109091183  UCSC
Coordinates (hg19) chr9:99680945-99681675  UCSC
Strand +
Parental Sequence NM_017761.4
Parental seq. overlap 640 bp
Parental seq. overlap (%) 26.6%
Genomic Region Intergenic
Retrocopy Summary PNRC2P5, located on chr9:96918663-96919393, is a retrocopy of the parental gene PNRC2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PNRC2
Full Name proline rich nuclear receptor coactivator 2
Also known as -
Coordinate chr1:23959164-23963462
Strand +
Gene summary Involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Located in Golgi apparatus; P-body; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PNRC2P3
Bonobo Pan paniscus PNRC2P4
Gorilla Gorilla gorilla PNRC2P2
Orangutan Pongo abelii PNRC2P4
Gibbon Nomascus leucogenys PNRC2P4
Green monkey Chlorocebus sabaeus PNRC2P2
Crab-eating macaque Macaca fascicularis PNRC2P3
Rhesus Macaca mulatta PNRC2P4
Golden snub-nosed monkey Rhinopithecus roxellana PNRC2P4
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PNRC2P5
CCTCCCTGGAAAGGGACGGAGAATTCCACATCCAGAGGGAGCCCTGCCGTCCATGGTTCTGAGCTTGAAGTCACCAGGACTTCTTTCAAACTTGTGTGCCGAGGAGACTCCCTTGTTGGCCTCAGTTCCCAGGCTGAACTCAGCAGCTCAGCCCATGAAAACTTCTGTATTGAGACAAAGGAAAGGATCTGTCAGAAAGCAACACCTATTGTCCTGAACTTGACACTAAGAAAGAGGACAAGTGATAAAGAAACTGAAGACAAGTGGTAGAGAGAGGTGTAACATTCCAGCCCCTCAACCTAGAAATGTTAGTAGAATCAACAACAGCTTAACAGACCAAGAGTCAGAATCCCCCAATGAAGATTCTTCATAAGAAAAAAGAAAGAAGACAGGGATATAACTCATCAGCAGCTGCAGGGCAGGCCATGCAAGACGGGGGAAAGAACAAAAATTTTCCAAAAAATCAAAATTGGAACTCTGAACTTTTCAGGTCCCAGCTTACTTTTTAAATCTCAAGCTAATCAGAACTTTGCCAGGGCCAAATGTAGTGAACCTCCATCACCAAGTGTTCTTCCCAAACCACCAAGCTGTTTCCTTTAATTCTTCCGATAAGGCAATAATGACATTTTAACTTAAAACCTTACTTAAAGTACAGGTACAAAATAAGATAAAGTACTAATGTTTACATTTAGCTATGTTTACAGATAGTTGTCAACTGGTCTAAAACAAAT
>NM_017761.4
GTCGGTAGAGGCAGAAGGAGAAGGTCGGGTTGTAGAAGCTGGGGTGGCCGGCAGCTCGCTCATCGGTGTTCGTGGGCTTTGTCGGTCCGTGCCTCGTCTCTCCCTGGAAAGGGAGGGAGGCTTCGACGTCGAGAGGGAGCCGCTGCCGCGTTAGTTCCGAGCTTGAAGTCACTAGGACTTCTCTCAAACTTGTGTGCTGAGGAGACTCAGATGTTGGCCTCAGCTCCTAGGCTGAACTCAGCAGATCGGCCCATGAAAACTTCTGTATTGAGACAAAGGAAGGGATCTGTCAGAAAGCAACACTTGTTATCTTGGGCTTGGCAGCAAGGAAGAGGACAGGTAGTGGAGATCCTGCAATCTGAAAAGCAGACTGAAAGGTGACAAAGAAGCTGAAGATGGGTGGTGGAGAGAGGTATAACATTCCAGCCCCTCAATCTAGAAATGTTAGTAAGAACCAACAACAGCTTAACAGACAGAAGACCAAGGAACAGAATTCCCAGATGAAGATTGTTCATAAGAAAAAAGAAAGAGGACATGGTTATAACTCATCAGCAGCTGCCTGGCAGGCCATGCAAAATGGGGGGAAGAACAAAAATTTTCCAAATAATCAAAGTTGGAATTCTAGCTTATCAGGTCCCAGGTTACTTTTTAAATCTCAAGCTAATCAGAACTATGCTGGTGCCAAATTTAGTGAGCCGCCATCACCAAGTGTTCTTCCCAAACCACCAAGCCACTGGGTCCCTGTTTCCTTTAATCCTTCAGATAAGGAAATAATGACATTTCAACTTAAAACCTTACTTAAAGTACAGGTATAAAATAAGACAAATGTTTAAATTTAGTTATGTTCACGGATAGTTGTCAATTGGTCTGAAACAAATTCGCTAGGGAATCTATTTGTGTAGAACTAATTAATGTAAAAAAAATAGACCATCTCGTGTTGTGTGCACTGTGATATAATGGTAGTATCAGTGCAACTTAAACTAATGATTGTACTTGATATTAAGTGTTCTCAACTGAGTAACTTTTAAGTGGAAACCAAGTTTAGATTTGGGGAGTGGTAAAGGAATCAGCTTTTTCTATTGTTAGGGGAAGACAGTAATTTATCATTCATGGACCAGTAGATTGTTGAAAGTTGGTGAATCGGATTATAAGCTTCTAGCTAACACAAGGATTCAGAATTAGGTAAACATCTGAAGGTTTAGTATATTAGAAACACCCAAACCAGTAATATGCTAACCTGATGCACTGCTGAAAGAAAATGTGAATTTTTCGTAATAATTGCATTTTAGTGAATTGTACAGTGGGTGGAAAGGGCATTTGGAGCTCATTAGAATGAGACATAGTACACCCCAATGGCCCTGTTTATTAAATGTAGTGGATTAAGTGTCTGTCAACAAATACACCAAAACCATTTTTTATAGAAACAGTATTTAATGGTCACTCAATAGCTTTCAAAATACATTTTTGTATTACAGCACTGCACAAGCTATTCTAATAGTGCTCTGGCCTCATCATTCCTGCAAAGCTTGCTTTGGGGAGTTGGATAATGTGAAAATTTTAAGTACCTAGGGGAGAAAGAGCCATGTAAATATCTGTAATAAACTTGTAGCATATGTAAAGTTTTCTTGGCCTTTATCTTACAAAAATGGAGTATTTTAGTATGAATTTGCTGAATGTAAGACCGTGGACTGTTTTTTATAATATGGCCTAATTTTAAAGGTCCAAAATAACTTGTTTTTAAAGTTTGCCCTTGTGCTAAAGTGCCAGTGTATGTATGTTATACTTGATTTGGTTGTAAACTATATTTCAAAGTAAACCCTAGTGTAATAAGTTTTATAACTAAAAAGGTTTAAGCTGCTAAAACTATTTTTAAGAGATGTGAAATGCAGTATGGGACTATCTTTTTTTCCTCCTCTAAGCCCAAAGATTAACTAGAGTCCCTCCAACCTTATAGATTGTTGGCTTTCACAATCTTATAACCTAGGATACAGGTAGTTTCGAGTATGGTGCCAGTGATGTTTTGTTTTTGTTTGGTCAAGGGGTAGGTGCAACCCAATGGACCACTTATGCAAAAGATGTAAACTCTTGCATAATACATTGATAACATGTTTTGCCAACTTTAAATGCTTAAACATAAGCGAAACCAGTAGCAAGTATGTGGGTCAGCTTAAAAATTTTGATTGTTAATGCCCTATTTTCTAATTTGGCACCTCTTGATGCCTAAGCAGGTAAGCAGATGCCTAAGCTGTATTTCTCCAAATAAATCAAGATGAAGTACTGCCCAAGTTAAATATTGATAGCCTAAAGACAAGTTTATGTAGTACTTAATGTACATGATATGAATGTGAAGCATAAAATTAAATAAAATTTTTCCCCATTGGCTTGGTTTTATTTTAAAAA

Publications

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