Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name YRDCP2
Plot displaying the genomic locations of a retrocopy (in chr9) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr9:96955036-96955558  UCSC
Coordinates (T2T) chr9:109126815-109127337  UCSC
Coordinates (hg19) chr9:99717318-99717840  UCSC
Strand +
Parental Sequence NM_024640.4
Parental seq. overlap 452 bp
Parental seq. overlap (%) 24.4%
Genomic Region Intragenic (MFSD14CP)
Retrocopy Summary YRDCP2, located on chr9:96955036-96955558, is a retrocopy of the parental gene YRDC. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name YRDC
Full Name yrdC N6-threonylcarbamoyltransferase domain containing
Also known as DRIP3|GAMOS10|IRIP|SUA5
Coordinate chr1:37802945-37808208
Strand -
Gene summary Predicted to enable nucleotidyltransferase activity and tRNA binding activity. Acts upstream of or within negative regulation of transport. Predicted to be located in membrane and mitochondrion. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Gorilla Gorilla gorilla YRDCP1
Gibbon Nomascus leucogenys YRDCP1
Green monkey Chlorocebus sabaeus YRDCP2
Crab-eating macaque Macaca fascicularis YRDCP2
Rhesus Macaca mulatta YRDCP2
Baboon Papio anubis YRDCP2
Marmoset Callithrix jacchus YRDCP1
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Orangutan Pongo abelii Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>YRDCP2
AGCTCCTCAAAGACCTAGTGCCAGGACGAGTGTCCCTGGTGATGGAACGTTCAGAGGAGCTCAACAACGACCTAAACCCCTTTACTCCTCTTACAAGGTATCCGGATTCCTGATTATGCCTTTATGCAAGACTTGGCCAAGATGTATGAGCATCCTCTTGCTCTCACTAGTGCCAACCTCAGCTCCCAGGACAGTTCTCTGAATGCCATGGAGTTATAAGACCTCTGGCCTCAGTTGTCCTTGGTCATTGATGGGGGACAAGCTAGGGATAGCCAGATCCCTGAGTGTTACCTTGGCTCAACTGTGGTTGACTTATCTGTGCATAGAAAGTTTGGCATCATTCGTCCAGGCTGTGTCCTGGAAAGTACTACAGCCTTTCTTCAACAGAGGTATGGGTTGCACCCCTCATGTGCATCCTACTTGTGAAACTCAGGAAGCAGGAAGGCCCATGGCCTGGTGCTGGACACTCTGTGTCCGTCCACTGATAATTGCCAAGCCCTCATTTGCAGAAGCCACTGGAGCT
>NM_024640.4
ACTTCCTCCCGGAAGCGGGCCTGGGCGGATGTCTCCGGCGCGTCGGTGCAGGGGGATGAGGGCCGCGGTGGCTGCCAGCGTGGGGTTGAGCGAGGGGCCTGCTGGCTCCCGGAGCGGTCGCCTCTTCCGCCCGCCGAGtcccgctccggcggcccccggcgcccggctgttgcggctcccggGGAGCGGGGCCGTGCAGGCCGCGAGCCCGGAGCGCGCCGGCTGGACCGAGGCGCTGCGGGCCGCCGTGGCCGAGCTGCGCGCCGGCGCCGTGGTGGCCGTCCCCACCGATACGCTGTACGGCCTGGCCTGCGCGGCGAGCTGCTCGGCGGCTCTGCGCGCTGTGTACCGCCTCAAGGGTCGCAGCGAGGCCAAGCCTCTGGCCGTATGCCTCGGCCGCGTGGCCGACGTCTACAGATACTGCCGTGTGAGAGTACCTGAGGGGCTCCTGAAAGACCTACTGCCAGGACCAGTGACCCTGGTGATGGAACGCTCGGAGGAGCTCAacaaggacctaaacccttttacgcctCTTGTAGGCATTCGGATTCCTGATCATGCTTTTATGCAAGACTTGGCTCAGATGTTTGAGGGTCCGCTTGCTCTCACTAGTGCCAACCTCAGCTCCCAGGCCAGTTCTCTGAATGTCGAGGAGTTCCAGGATCTCTGGCCTCAGTTGTCCTTGGTTATTGATGGGGGACAAATTGGGGATGGCCAGAGCCCCGAGTGTCGCCTTGGCTCAACTGTGGTTGATTTGTCTGTGCCCGGAAAGTTTGGCATCATTCGTCCAGGCTGTGCCCTGGAAAGTACTACAGCCATCCTCCAACAGAAGTACGGACTGCTCCCCTCACATGCGTCCTACCTGTGAAACTCTGGGAAGCAGGAAGGCCCAAGACCTGGTGCTGGATACTATGTGTCTGTCCACTGACGACTGTCAAGGCCTCATTTGCAGAGGCCACCGGAGCTAGGGCACTAGCCTGACTTTTAAGGCAGTGTGTCTTTCTGAGCACTGTAGACCAAGCCCTTGGAGCTGCTGGTTTAGCCTTGCACCTGGGGAAAGGATGTATTTATTTGTATTTTCATATATCAGCCAAAAGCTGAATGGAAAAGTTAAGAACATTCCTAGGTGGCCTTATTCTAATAAGTTTCTTCTGTCTGTTTTGTTTTTCAATTGAAAAGTAATTAAATAACAGATTTAGAATCTAGTGAGAGCCTCCTCTCTGGTGGGTGGTGGCATTTAAGGTTCAAACCAGCCAGAAGTGCTGGTGCTGTTTAAAAAGTCTCAGGTggctgcgtgtggtggctcatgcctgtaatcccaacattctgggaggcccaggcgggagaactgcttgagcccaggagttcagaatcagcctgggcaacatagcaatactccgtctcataaaaattaataaataaaaAGTCTCAGGTGACCAAAGGCTCCTGAAGCTAGAACCAGGTTTGGATAAAGATTGAAGAGCCACAGGCCACTCTTCCCTCTGAGCCATTGGGCCTAGTGGTGTCATGTATTGTAATTGCTCGCAGGGAGAGCAGTCTTTTTGGTGTAATAGTGGGATGTCTGCTTAGTTGGCAGGGGTTCAGTCCAAATGGAAGAATATTGGGAAATAAACCTCCACTATCCTTTATAGCCAGGGACTTTTTTCTTATTTATTCATAAAATAAATTATAGTTAATTATACCCATAACACCTTTATTTAAATCCAGTGTTCTCCGCAGCCTTTTGTCTATTTATATGTGTACCAAGTGTTAAACATAATtattattgggcatttgaactttgtttttctttaaagaaatgctgctattaaacatatttgtaaatgg

Publications

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