Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RAD21P1
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr8). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:100801111-100804598  UCSC
Coordinates (T2T) chrX:99243643-99247130  UCSC
Coordinates (hg19) chrX:100056100-100059587  UCSC
Strand +
Parental Sequence NM_006265.3
Parental seq. overlap 3274 bp
Parental seq. overlap (%) 89.2%
Genomic Region Intergenic
Retrocopy Summary RAD21P1, located on chrX:100801111-100804598, is a retrocopy of the parental gene RAD21. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RAD21
Full Name RAD21 cohesin complex component
Also known as CDLS4|HR21|HRAD21|MCD1|MGS|NXP1|SCC1|hHR21
Coordinate chr8:116845934-116874776
Strand -
Gene summary The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Gorilla Gorilla gorilla RAD21P1
Orangutan Pongo abelii RAD21P1
Gibbon Nomascus leucogenys RAD21P1
Green monkey Chlorocebus sabaeus RAD21P2
Crab-eating macaque Macaca fascicularis RAD21P2
Rhesus Macaca mulatta RAD21P2
Baboon Papio anubis RAD21P2
Golden snub-nosed monkey Rhinopithecus roxellana RAD21P1
Marmoset Callithrix jacchus RAD21P1
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RAD21P1
GACCCAGCCTGCCCAACTCCCAGTGGAGAGCAAGGTTTCCTTCTATTTTCATAGGCAACCAGAACAATGTTCTATGCACATTTTGTCCTCAGTAAGAGGGCCTCTGGCCAAAATTTGGCTAGCGGCCCATTGGGATAAGAAGCTAACCAAAGCCCCTGTGTTACAGTGTAATTTAGAGAGCAGCATGGAGAGTATCATCTCACCAAAGGTGAAGATAGCATTACGGACATCAGGACATCTCTTACTGGGAGTAGTTTGAATCTATCACAGGAAAGCCAAATATCTTCTTGCAGACTGTAATGAAGCATTCATTAAGATAAAGATGGCTTTTTGATCAGGTGTTGACCTGCCTGAGGAAAATCAGGAAGCAGCTTATAACACCATTACTTTACTTGAATAATTTCATGACTTTGATCAGCCACTGCCTGACTTAGATGACATCGATGTGGCCCAGAAGTTCAGCCTGGGTCAGAGTAGAGTGGAAGAAATAACCGTGAGAGAAGAAGTTGGGAATATCAGTATTTTACAAGAAAATGGTTTTGGCGATTTTGGAATGGATGATCATTGAGATCAGAGAAAGCAGTGCTTTTGAGGATGATGACATGTTAGTAGGCACTACTGCTTCTAATCTCCTATTAGAGTCTGAACAGAGCACCAGCAATCTGAATGAGAAAATTAACCATTTAGAATATGAAGACCAATATAAAGATAATAATTTTGGAGAAGGAAATGATGGTGGAATATTAGAAGACAAACTTATTAGTAATAATGATGGTAGTATCTTTGATGATCCCCCTGCCCTCTCTGAGGCAGAGGTAATGTTGCCAGAGCAGCCTGCACATGATGATATACGGGTGAGGATGATAATACATCAATGGGTGGGCCTGATAGTCCTGATTCAGTGAATCCTGTTGAACCAGCCAACTATGACTGATCAAACAACACTTGTTCCAAATGAGGAAGAAGCATTTGCATTGGAACCTATTGATATAACTGTTAAAGAAACAAACGCCAAGAGGAAGAGGAAGCTAATTGTTGACAGTGTCAAAAACTTGGATAGCAAGACAATTAGAGCCCAGCTTAATGATTATTCTGATATTGTTACTACTTTGGATCTGGCACCACCCACCAAGAAATAGGTGATGTGGAAAGAGACAGGAGTAGTAGAAAAACTGTTTTCTTTACCTGCTCAGCCTTTGTGGAATAACAGACTACTGACGCTCTTTACATGCTGTCTTACACCACTTGTACCAGAAGACCTTAGAAAAAGGGGGAAAGGAGGGACAGATAATTTGGATGAGTTCCTCAAAGAACTTGAAAATCCAGAGGTTCCTAGAGAGAACTAGCAACAGCTACACCAGCAGCATGATGTTATTGATAAGCCCATTTTGGAAGAGCCAAGCCATCTCCAGAAGTCAGTGATGAGGCCAGCAGAACAAATCTGGATGAGTCAGCTATGCCTCCACCACCACCTCAGGGAGTTAAGTGAAAAGCTGGACAAATTAACCCAGAGCCTGTGATGCCTCCTCAGCAGGTTGAGCAGATGGAAATACTGCCTGTAGAGCTTCCCCAAGAAGAACCTCCAAATATCTGTCAGCTAATACCAGAGTTAGAACTTCTGCCAGAAAAAGAGAATGAGAAAGAAAAGGGGAAAAAAAGATGATGAAGGGGAAAAGGATGAAGATGTTTCAGGGGGTGATCAAGATCAGGAAGAAAGAAGATGGAAGAAAAGGACTCAGCAGATGCTTCACGGTCTTCAGTGAGCTCTTGCTAAAACTGGAGCTGAATCTATCAGTTTGCTTGAGTTATATCAAAACACAAACAGAAAACAAACTGTTGCAAAGTTCTACAGCTTCTTGGTTCTTAAAAAGCAGCAAGCTATTGAGCTGACACAGGAAGAACTGTACAGTAACATCATCGCAACACCCGGGCCAAAGTTCCATATTTTATGAGGAGCTAGAAGCATTATAGCTAGTGTTCATTTCACTAGTGCTTACAAATTGCCCCCATGTGTAGGAGACACAGAACCCTTTGAGAAAACTTAGATTTTTGTCTGTACAAAGTCTTTGCCTTTTTCTTTCTCATTTTTTCCCAGTATATTAAATTTGTCAGTTTCATCTTTGAGGGAAACTGATTAGATGGATGTGTTTGTGTTCTGATGGAGAAAACAGCACCCTAAGGACTCAGAAGATTAACAGTTCAGAACAGATGTGTGCAATATTGGTGCATGCAATGATGTTGAGTGGCAGTTGAAAGTCATGATTTTTATCTTAGTTCTTCATTACTGCATTGAAAAGGAAAACCTGTCTGGGAAAATGCCTGACAGTTTAATTTAAAACTATGGTATGAGTCTTTGAAAAGAAAAAAAAAAAGCCTTTCCATCAGTAGTAACACTGGCAATCTTCTTGTTAACCACTCTCCTTAGGGATGGTACCTGAAATAACAAAGGTCACCCTCTTGAGATTCGTTTTAAGTGTAATTCCCTAATGAGCAAACGTGTACGTGAAATTGTGTTGTGACTGATACCCTTCAGCTACAGATAGGACTGACTTGGTTTAAAGTGTTCTATTTTGTAAATCATTCCATTTGAGTCTTTCTGATGAACTTCGCTATCTCGAAATCTGTCATTTTAGTGAGGCTCCAAAATGAGCAGAAATAGGCCTGATTAGAGTAGAGTGACTATCAAATAGCAGACTTTCTAGGACCTATAAATAGAAGTTTTAAAAAGATGTTTGGATATATTTGACTATTCAGATCATGAAAACAGAAATTACCCTGCCTACTACAAGGACAGACTGATGGGAAATTATACACCAGGTCAACTTAACCTTTAAGCAGACAATGCTGTAAAAACTAATGGCTTCTCTGATATTTATTGTAAGTTTTAGTACTGATCTCCTTTTCCAGTGCTGCACACTCCTGTGTTTGGAACTTTAATAGCTTTGCAACGAAATCCTATATCCGGTTTCCTATAATTTAACTGAAGAAAAACACATCCAAATAAAGGTCTATATTAACAGACCAGATAGCATCAGAAATCATGTGACTATTATGATTATCAGAATATGTCTTAACTTTTTAGGGCAAAATTAACACTGAAAGTTCTAGCTTAAGTGTTGACACTTTCGTGGGGAAAAAAATCACTTTTGAAACAGACTTCAGTGTATACTCAATAATTTAAAATTATGTGAAATGTTTTAAATTTGTGAACTCATTACTGTTTTAATGATTCCGTTTCTTGAGAGTTTAACCATAAAAAATTGCTATTGCAGATTTATTTTCAATATGCTGTGCCTGTAAACCATGGAGTTTTCCCTGTTTGTAAAAAGACATTGTAGATAATTGAATGTTTGATTTTAGAAAGGTCATTGGTTTCTTGTTACACATTTTGTTAGTCTGTTTTTTTTGCTTATTGGGTTTAATATTGTTCTTGAAAATAGTTGATGCTATGTTATGTATAACTCTTCTAATAAAAGTTGTGTTATAAG
>NM_006265.3
ATCTTGTTTGTTTGAGTGAATCGGAAAGGAGGCGCCGGCTGTGGCGGCGGCGGGAGCTGCTCGGAAGCTACACCTCGCAAGGGCTCCcccctttccccaccccctcccccgacccttttcccctccccGGGCCACCCAGCCCGCCCAACTCCCAGCGGAGAGCAAGGTTTTCTTCTGTTTTCATAGCCAGCCAGAACAATGTTCTACGCACATTTTGTTCTCAGTAAAAGAGGGCCTCTGGCCAAAATTTGGCTAGCGGCCCATTGGGATAAGAAGCTAACCAAAGCCCATGTGTTCGAGTGTAATTTAGAGAGCAGCGTGGAGAGTATCATCTCACCAAAGGTGAAAATGGCATTACGGACATCAGGACATCTCTTACTGGGAGTAGTTCGAATCTATCACAGGAAAGCCAAATACCTTCTTGCAGACTGTAATGAAGCATTCATTAAGATAAAGATGGCTTTTCGGCCAGGTGTGGTTGACCTGCCTGAGGAAAATCGGGAAGCAGCTTATAATGCCATTACTTTACCTGAAGAATTTCATGACTTTGATCAGCCACTGCCTGACTTAGATGACATCGATGTGGCCCAGCAGTTCAGCTTGAATCAGAGTAGAGTGGAAGAGATAACCATGAGAGAAGAAGTTGGGAACATCAGTATTTTACAAGAAAATGATTTTGGTGATTTTGGAATGGATGATCGTGAGATAATGAGAGAAGGCAGTGCTTTTGAGGATGACGACATGTTAGTAAGCACTACTACTTCTAACCTCCTATTAGAGTCTGAACAGAGCACCAGCAATCTGAATGAGAAAATTAACCATTTAGAATATGAAGATCAATATAAGGATGATAATTTTGGAGAAGGAAATGATGGTGGAATATTAGATGACAAACTTATTAGTAATAATGATGGCGGTATCTTTGATGATCCCCCTGCCCTCTCTGAGGCAGGGGTGATGTTGCCAGAGCAGCCTGCACATGACGATATGGATGAGGATGATAATGTATCAATGGGTGGGCCTGATAGTCCTGATTCAGTGGATCCCGTTGAACCAATGCCAACCATGACTGATCAAACAACACTTGTTCCAAATGAGGAAGAAGCATTTGCATTGGAGCCTATTGATATAACTGTTAAAGAAACAAAAGCCAAGAGGAAGAGGAAGCTAATTGTTGACAGTGTCAAAGAGTTGGATAGCAAGACAATTAGAGCCCAACTTAGTGATTATTCAGATATTGTTACTACTTTGGATCTGGCACCGCCCACCAAGAAATTGATGATGTGGAAAGAGACAGGAGGAGTAGAAAAACTGTTTTCTTTACCTGCTCAGCCTTTGTGGAATAACAGACTACTGAAGCTCTTTACACGCTGTCTTACACCGCTTGTACCAGAAGACCTTAGAAAAAGGAGGAAAGGAGGAGAGGCAGATAATTTGGATGAATTCCTCAAAGAATTTGAAAATCCAGAGGTTCCTAGAGAGGACcagcaacagcagcatcagcagcGTGATGTTATCGATGAGCCCATTATTGAAGAGCCAAGCCGCCTCCAGGAGTCAGTGATGGAGGCCAGCAGAACAAACATAGATGAGTCAGCTATGCCTCCACCACCACCTCAGGGAGTTAAGCGAAAAGCTGGACAAATTGACCCAGAGCCTGTGATGCCTCCTCAGCAGGTAGAGCAGATGGAAATACCACCTGTAGAGCTTCCCCCAGAAGAACCTCCAAATATCTGTCAGCTAATACCAGAGTTAGAACTTCTGCCagaaaaagagaaggagaaagagaaggaaaaagaagatgatgaagaggaagagGATGAAGATGCATCAGGGGGCGATCAAGATCAGGAAGAAAGAAGATGGAACAAAAGGACTCAGCAGATGCTTCATGGTCTTCAGCGTGCTCTTGCTAAAACTGGAGCTGAATCTATCAGTTTGCTTGAGTTATGTCGAAATACGAACAGAAAACAAGCTGCCGCAAAGTTCTACAGCTTCTTGGTTCTTAAAAAGCAGCAAGCTATTGAGCTGACACAGGAAGAACCGTACAGTGACATCATCGCAACACCTGGACCAAGGTTCCATATTATATAAGGAGCTAGAAGCATTATAGCTAGTGTTTGATTCACTAGTGCTTACAAATTGCCCCCATGTGTAGGGGACACAGAACCCTTTGAGAAAACTTAGATTTTTGTCTGTACAAAGTCTTTGCCTTTTTCCTTCTTCATTTTTTTCCAGTACATTAAATTTGTCAATTTCATCTTTGAGGGAAACTGATTAGATGGGTTGTGTTTGTGTTCTGATGGAGAAAACAGCACCCCAAGGACTCAGAAGATGATTTTAACAGTTCAGAACAGATGTGTGCAATATTGGTGCATGTAATAATGTTGAGTGGCAGTCAAAAGTCATGATTTTTATCTTAGTTCTTCATTACTGCATTGAAAAGGAAAACCTGTCTGAGAAAATGCCTGACAGTTTAATTTAAAACTATGGTGTAAGTCTTTGACAAGAAAAAAAAACAAACAAACACTTCTTTCCATCAGTAACACTGGCAATCTTCCTGTTAACCACTCTCCTTAGGGATGGTATCTGAAACAACAATGGTCACCCTCTTGAGATTCGTTTTAAGTGTAATTCCATAATGAGCAGAGGTGTACGCGAAATTGTGTTATGACTGATAGCCTTCAGCTACAAAAAGATAGGACTGACCTGGTTTAAAGTGTTCTATTTTGTAAATCATTCCATTTGAGTCTTTCTGATGAACTTGGCTATACTGAAATCTGTTATTTTAGTGAGGCTCCAAAATGAGCAAAGCTAGGCCTGATTAGAGTAGAGTGACTATTAAAAAACATAACTTTCTAGGAGCTATAAATCAAAGTTTTAAAAAGATGTTTGGATATATTTGAGTATTCCGATCATGAAAACAGAAATTGCCCTGCCTACTACAAGGACAGACTGATGGGAAATTATGCACCTGGTCAACTTAGCTTTTAAGCAGACGATGCTGTAAAAACTAACGGCTTCTCTGATATTTATTGTAAGTTTTAGTACTGATCTCCTTTTCCAGTGCTGCACACTCCTGGTTTGGAACTTTAATAGCGTTGCAACGAAATCCTATATCCAGTTTCCTGTAATTTAATTGAAGAAAAATACATCCAAATAAAGACTTTATTATTAACAGACCAGATAGCATCAGAAATCATGTGACTGTTATGATTATCAGAATGTCTTAACTTTTTAGGGCAAAGTTAACACTGAAAGTTCTAGCTTAAGTGTTGAAACTTTTGTGGGAAAAAAAAATCACTTTTGAAACTCAGACTTCAGTGTATACCCAATAATTTAAAATTATGTGAAATGTTTTAAATTTGTGAACTCGTAATTACTGTTTTAATGATTCAGTTTCTTCAGAGTGGTAATTGTATAAAATTGCTATTGCAGCTTTACATTCAATATGATGTGCCTGTAAACCAAGGAGTTTTCCCCGTTTGTAAAAAGACATTGTAGATAATTGAATGTTTGATTTTAGAAAGGTCATTAGTTTCTTGTTACACATTTTGTTAGTCTGGTTTTTGTTGCTTATCGGGTTTAATATTGTTCTTGAAAATAGTTGATGCTATGTTATGTATAACTTTTCTAATAAAAGTTGTGTTATAAGCTGTA

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