Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name GK4P
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:101777013-101780653  UCSC
Coordinates (T2T) chrX:100221612-100225252  UCSC
Coordinates (hg19) chrX:101031986-101035626  UCSC
Strand -
Parental Sequence NM_001128127.3
Parental seq. overlap 3608 bp
Parental seq. overlap (%) 80.2%
Genomic Region Intergenic
Retrocopy Summary GK4P, located on chrX:101777013-101780653, is a retrocopy of the parental gene GK. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name GK
Full Name glycerol kinase
Also known as GK1|GKD
Coordinate chrX:30653348-30731462
Strand +
Gene summary The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes GKP4
Bonobo Pan paniscus GKP4
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>GK4P
GTTCAGCGGACGCGCGCGGCCTCGATCTCTGGACTCGTCACCTGCCCCTCCCCCTCCCGCCGCCGTCACCCAGGAAACCGGCCGCAATCGCCGGCCGACCTGAAGCTGGTTTCGTGGCAGCCTCAAAGAAGGCAGTTTTGGGGCCATTGGTGGGGGCGGTGGACCAGGGCACCAGTTCGACGAGCTTTTTGGTTTTCAATTCAAAAACAGCTGAACTACTTAGTCATCATCAAGTAGAAATAAAACAAGAGTCCCCAAGAGAAGGATGGGTGGAACAGGACCCTAAGGAAATTCTACATTCTGTCTATGAGTGTATAGAGAAAACATGTGAGAAACTTGGACAGCTCAATATTGATATTTCCAACATAAAAGCTATTGGTGTCAGCAACCAGAGGGAAACCACTGTAGTCTGGGACAAGATAACTGGAGAGCCTCTCTACAATGCTGTGGTGTGGCTTGATCTAAGAACCCAGTCTACCGTTGAGAGTCTTAGTAAAAGAATTCCAGGAAATAATAACTTTGTCAAGTCCAAGACAGGCCTTCCACTTAGCACTTACTTCAGTGCAGTGAAACTTCGTTGGCTCCTTGACAATGTGAGAAAAGTTCAAAAGGCCGTTGAAGAAAAATGAGCTCTTTTTGGGACTATTGATTCATGGCTTATTTGGAATTTGACAGGAGGAGTCAATGGAGGTGTCCACTGTACAGATGTAACAAATGCAAGTAGGACTATGCTTTTCAACATTCATTCTTTGGAATGGGATAAACAACTCTGCGAATTTTTTGGAATTCCAATGGAAATTCTTCCAAATGTCCGGAGTTCTTCTGAGATCTATGGCCTAATGAAAGCTGGGGCCTTGGAAGGTGTGCCAATATCTGGGTGTTTAGGGGACCAGTCTGCTGCATTGGTGGGACAAATGTGCTTCCAGATTGGACAAGCCAAAAATACGTATGGAACAGGATGTTTCTTACTGTGTAATACAGGCCATAAGTGTGTATTTTCTGATCATGGCCTTCTCACCACAGTGGCTTACAAACTTGGCAGAGACAAACCAGTATATTATGCTTTGGAAGGTTCTGTAGCTATAGCTGGTGCTGTTATTCGCTGGCTAAGAGACAATCTTGGAATTATAAAGACCTCAGAAGAAATTGAAAAACTTGCTAAAGAAGTAGGTACTTCTTATGGCTGCTACTTCGTCCCAGCATTTTCGGGGTTATATGCACCTTATTGGGAGCCCAGCACAAGAGGGATAATCTGTGGACTCACTCAGTTCACCAATAAATGCCATATTGCTTTTGCTGCATTAGAAGCTGTTTGTTTCCAAACTCGAGAGATTTTGGATGCCATGAATCGAGACTGTGGAATTCCACTCAGTCATTTGCAGGTAGATGGAGGAATGACCAGCAACAAAATTCTTATGCAGCTACAAGCAGACATTCTGTATATACCAGTAGTGAAGCCCTCAATGCCCGAAACCACTGCACTGGGTGCTGCTATGGAGGCAGGGGCTGCAGAAGGAGTCGGCGTATGGAGTCTCGAACCCGAGGATTTGTCTGCCGTCACGATGGAGCGGTTTGAACCTCAGATTAATGCTGAGGAAAGTGAAATTCGTTATTCTACATGGAAGAAAGCTGTGATGAAGTCAATGGGTTGGGTTACAACTCAATCTCCAGAAAGTGGTGACCCTAGTATCTTCTGTAGTCTGCCCTTGGGCTTTTTTATAGTGAGTAGCATGGTAATGTTAATCGGAGCAAGGTACATCTCAGGTATTCCATAAAACCTACCAAATCATGGATTCCCAAGATGTGAGCTTTTTACATAATGAAAGAACCCAGCAATTCTGTCTCTTAATGCAATGACACTATTCATAGACTTTGATTTTATTTATAAGCCACTTGCTGCATGACCCTCCAAGTAGACCTGTGGCTTAAAATAAAGAAAATGCAGCAAAAAGAATGCTATAGAAATATTTGGTGTTTTTTTTTTTTTAAACATCCACAGTTAAGGTTGGGCCAGCTACCTTTGGGGCTGACCCCCTCCATTGCCATAACATCCTGCTCCATTCCCTCTAAGATGTAGGAAGAATTCGGATCCTTACCATTGGAATCTTCCATCGAACATACTCAAACACTATTGGACCAGGATTTGAGTCTCTGCATGACATATACTTGATTAAAAGGTTATTACTAACCTGTTAAAAATCAGCAGCTCTTTGCTTTTAACAGACACCCTAAAAGTCTTCTTTTCTACATAGTTGAAGACAGCAACATCTTCACTGAATGTTTGAATAGAAACCTCTACTAAATTATTAAAATAGACATTTAGTGTTCTCACAGCTTGGATATTTTTCTGAAAAGTTATTTGCCAAAACTGAAATCCTTCAGATGTTTTCCATGGTCCCACTAATTATAATGACTTTCTGTCTGGATCTTATAGGAAAGGATACTTTCTTTTTTCTTCCATCTTTCCTTTTTATATTTTTTACTTTGTATGTATAACATACATGCCTATATATTTTATACACTGAGGGTAGCCCATTTATAAATTAAGAGCACATTATATTCAGAAGGTTCTAACAGGGCTGGTCTTAAGTGAACCACTGTGTATATAAATATGTTGGAAAACAGCTGTATACATTTTTGGGCAACGGTTATGCATAATATTTACCAGGAGAATTTTTTTCTTAACAAGCCAACATTTAAAATTTATGTTTTATGTCAATAAAAGGAAATATACTTTATTGTGACTTCAACTATATTTCTTATCCCTTACATTTTTATTTAATTGTCTTAGCTTAAAAAAAATAAGAAACTGTGGAATACTACAGTAAATATTGTTTTCAAACACAAGCAATAATTCAAATAGTTATTTTTCTTTTGAATTAATTGTAGACATATTTTGGATCCTATTGAGGGGATAAGAGGATGTCAAAAAAGTTAAATACCTAAGTAGAAAAAAATATAGAAATAAAGCCAAGAATCTCTTTCAGTTCAAATGTTATCAATTGTTAATAAGAAATTGCTATCTGGGATGACAGAATTATCTCTGCTTAGTGTCTTATTATAACTGAAAGAAGGTTTATCATTACAAATGCCTTCCAATGAAACCAAGAATTTCTCAAAATATTTAATGTCACATATTATAAGAAGTTACCTAATCCTGCTTCTTAACGTCAATTTTTAAAAATATCTTAAAATTACTTTGTTTTGCAGTAAACAGTGAAGAAAAGATTGCCTCCTAATTATTTTTTTCAACAAGTGCTGAATAGGAAAACATTTATATCTTACTATAAAAGGTTCTGTTTTGTTTGGAATTAATGGTAGCTTTATTGACTGTTCTGATTGTGCTGTTTCTGAATTATTGAATCTGCTAGGTTTTATTCATGCAGCCACCACTTAAGTGACATAAATATTATAGAAAGGTACTGTGAAATGATCACTTTGTGGCAGGGGTACTTTTAAACATAAATGTTTCTACAAAAGTAGGTTGAGTTCATTGTAAATAATTGTGAAAGCCACTGTTCAAATAATTTTAAGATTACATTAATTTTTCTATAAACTGCAAGATTTATAAATGTTTGAAATTGTACACATTGATATTTAATGACAAATTTACTTAAAATAAATTGACCCCTTGTTCTTAA
>NM_001128127.3
GCGTTCAGCGGACGCGCGCGGCCTCGATCTCTGGACTCGTCACCTGCCCCTCCCCCTCCCGCCGCCGTCACCCAGGAAACCGGCCGCAATCGCCGGCCGACCTGAAGCTGGTTTCATGGCAGCCTCAAAGAAGGCAGTTTTGGGGCCATTGGTGGGGGCGGTGGACCAGGGCACCAGTTCGACGCGCTTTTTGGTTTTCAATTCAAAAACAGCTGAACTACTTAGTCATCATCAAGTAGAAATAAAACAAGAGTTCCCAAGAGAAGGATGGGTGGAACAGGACCCTAAGGAAATTCTACATTCTGTCTATGAGTGTATAGAGAAAACATGTGAGAAACTTGGACAGCTCAATATTGATATTTCCAACATAAAAGCTATTGGTGTCAGCAACCAGAGGGAAACCACTGTAGTCTGGGACAAGATAACTGGAGAGCCTCTCTACAATGCTGTGGTGTGGCTTGATCTAAGAACCCAGTCTACCGTTGAGAGTCTTAGTAAAAGAATTCCAGGAAATAATAACTTTGTCAAGTCCAAGACAGGCCTTCCACTTAGCACTTACTTCAGTGCAGTGAAACTTCGTTGGCTCCTTGACAATGTGAGAAAAGTTCAAAAGGCCGTTGAAGAAAAACGAGCTCTTTTTGGGACTATTGATTCATGGCTTATTTGGAGTTTGACAGGAGGAGTCAATGGAGGTGTCCACTGTACAGATGTAACAAATGCAAGTAGGACTATGCTTTTCAACATTCATTCTTTGGAATGGGATAAACAACTCTGCGAATTTTTTGGAATTCCAATGGAAATTCTTCCAAATGTCCGGAGTTCTTCTGAGATCTATGGCCTAATGAAAGCTGGGGCCTTGGAAGGTGTGCCAATATCTGGGTGTTTAGGGGACCAGTCTGCTGCATTGGTGGGACAAATGTGCTTCCAGATTGGACAAGCCAAAAATACGTATGGAACAGGATGTTTCTTACTATGTAATACAGGCCATAAGTGTGTATTTTCTGATCATGGCCTTCTCACCACAGTGGCTTACAAACTTGGCAGAGACAAACCAGTATATTATGCTTTGGAAGGTTCTGTAGCTATAGCTGGTGCTGTTATTCGCTGGCTAAGAGACAATCTTGGAATTATAAAGACCTCAGAAGAAATTGAAAAACTTGCTAAAGAAGTAGGTACTTCTTATGGCTGCTACTTCGTCCCAGCATTTTCGGGGTTATATGCACCTTATTGGGAGCCCAGCGCAAGAGGGATAATCTGTGGACTCACTCAGTTCACCAATAAATGCCATATTGCTTTTGCTGCATTAGAAGCTGTTTGTTTCCAAACTCGAGAGATTTTGGATGCCATGAATCGAGACTGTGGAATTCCACTCAGTCATTTGCAGGTAGATGGAGGAATGACCAGCAACAAAATTCTTATGCAGCTACAAGCAGACATTCTGTATATACCAGTAGTGAAGCCCTCAATGCCCGAAACCACTGCACTGGGTGCGGCTATGGCGGCAGGGGCTGCAGAAGGAGTCGGCGTATGGAGTCTCGAACCCGAGGATTTGTCTGCCGTCACGATGGAGCGGTTTGAACCTCAGATTAATGCGGAGGAAAGTGAAATTCGTTATTCTACATGGAAGAAAGCTGTGATGAAGTCAATGGGTTGGGTTACAACTCAATCTCCAGAAAGTGGTGACCCTAGTATCTTCTGTAGTCTGCCCTTGGGCTTTTTTATAGTGAGTAGCATGGTAATGTTAATCGGAGCAAGGTACATCTCAGGTATTCCATAAAACCTACCAACTCATGGATTCCCAAGATGTGAGCTTTTTACATAATGAAAGAACCCAGCAATTCTGTCTCTTAATGCAATGACACTATTCATAGACTTTGATTTTATTTATAAGCCACTTGCTGCATGACCCTCCAAGTAGACCTGTGGCTTAAAATAAAGAAAATGCAGCAAAAAGAATGCTATAGAAATATTTGGTGGTTTTTTTTTTTTTTAAACATCCACAGTTAAGGTTGGGCCAGCTACCTTTGGGGCTGACCCCCTCCATTGCCATAACATCCTGCTCCATTCCCTCTAAGATGTAGGAAGAATTCGGATCCTTACCATTGGAATCTTCCATCGAACATACTCAAACACTTTTGGACCAGGATTTGAGTCTCTGCATGACATATACTTGATTAAAAGGTTATTACTAACCTGTTAAAAATCAGCAGCTCTTTGCTTTTAACAGACACCCTAAAAGTCTTCTTTTCTACATAGTTGAAGACAGCAACATCTTCACTGAATGTTTGAATAGAAACCTCTACTAAATTATTAAAATAGACATTTAGTGTTCTCACAGCTTGGATATTTTTCTGAAAAGTTATTTGCCAAAACTGAAATCCTTCAGATGTTTTCCATGGTCCCACTAATTATAATGACTTTCTGTCTGGATCTTATAGGAAAAGATACTTTCTTTTTTCTTCCATCTTTCCTTTTTATATTTTTTACTTTGTATGTATAACATACATGCCTATATATTTTATACACTGAGGGTAGCCCATTTATAAATTAAGAGCACATTATATTCAGAAGGTTCTAACAGGGCTGGTCTTAAGTGAACCACTGTGTATATAAATATGTTGGAAAACAGCTGTATACATTTTTGGGCAACGGTTATGCATAATATTTACCAGGAGAATTTTTTTCTTAACAAGCCAACATTTAAAATTTATGTTTTATGTCAATAAAAGAAAATATACTTTATTGTGACTTCAACTATATTTCTTATCCCTTACATTTTTATTTAATTGTCTTAGCTTAAAAAAAGAAGAAACTGTGGAATACTACAGTAAATATTGTTTTCAAACACAAGCAATAATTCAAATAGTTATTTTTCTTTTGAATTAATTTTAGACATATTTTGGATCCTATTGAGGGGATAAGAGGATGTCAAAAAAGTTAAATACCTAAGTAGAAAAAAATATAGAAATAAAGCCAAGAATCTCTTTCAGTTCAAATGTTATCAATTGTTAATAAGAAATTGCTATCTGGGATGACAGAATTACCTCTGCTTAGTATCTCATTATAACTGAAAGAAGGTTTATCATTACAAATACCTTCCAATGAAACCAAGAATTTCTCAAAATATTTAATGTCACATATTATAAGAAGTTACCTAATCCTGCTTCTTAACATCAATTTTTAAAAATATCTTAAAATTACTTTGTTTTGTAGTAAACAGTGAAGAAAAGATTGCCTCCTAATTATTTTTTTCAATGAGTGCTGAATGGGAAAACATTTATATCTTACTATAAAAGGTTCTGTTTTGTTTGGAATCAATGGTAGCTTTATTGACTGTTCTGATTGTGCTGTTTCTAATTTATTGAATCTGCTAGGTTTTATTGATGCAGCCACCACTTAAGTGACATAAATATTATAGAAAGGTACTGTGAAATGATCACTTTGTGGCAGGGGTACTTTTAAACATAAATGTTTCTACAAAAGTAGGTTGAGTTCATTGTAAATAATTGTGAAAGCCACTGTTCAAATAATTTTAAGATTACATTAATTTTTCTATAAATTGGAAGATTTATAAATGTTTGAAATTGTACACATTGATATTTAATGACAAATTTACTTAAAATAAATTGACCCCTTGTTCTTACTTGCATTTCTCATTTACAGACTAGAACTTAGTTGAAAGTTAAATTAAGAAAGATGTTTCAGAggccgggcacggtggctgacgcctgtaatcccagcactttgggaggccgaggtgggcagatcacctgaggtcaggagttcgggactagcctaaccgacatggagaaaccctatctctactaaaaaaaaaaaaaGATGTTTCAGGACATGTGAAACTTGGCTGTTAGCGCTTGATAGGGCACACTCTGAAGAGTTAACCAACAGCCAAAGAAGTAATTTCTGTAATGATGAACACTTTAATCATTCTATTAGAAGAAACTACACTGTCCCATCTCAGCATTTGCAAAAAATAATGTTGGTAAGGTCAGCAGCCATTATCAACAGGGCCTTGCATGGCTAACTTTGACCACCATTTTTCTCTCAACCTGATAGGCAACACCTCAATCCTTTGTTCTCCAACTAATCAGTAAAATAAGTAATGCATCTCTGCTTCTGTAATGATATCTTAGAATTTTTAGTATGTTTCTTTTGAAGTGCCCAAAGCCCAATTCTTTGGGATATCTTTTGGGTATCTGGTATCATGTGGGAGTGAAGAAAGAAAGTTTTTGGAGAAACCAACAAATGAAAGCTGTGATAGCACAGAAGCTAATGGCATTGACAGTGGAGTAGGTAGTATTTAATCTGTAGTGTTTACAACATAGTAGATAGAAGTACAAAAATTTTTTTAACTATAACTCTTTAATAGCTTGTTTTATCTAGTAATATTTAAATAATGAAGTTTCCTTGATCCTTTGCTTTTGCAACCTAACAACTTTAATAATAAGTTCACACAATAAACAAATTAGTAGAAAA

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