Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CNEP1R1P1
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr16). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:103650524-103652132  UCSC
Coordinates (T2T) chrX:102097540-102099148  UCSC
Coordinates (hg19) chrX:102905452-102907060  UCSC
Strand -
Parental Sequence NM_001281789.2
Parental seq. overlap 1494 bp
Parental seq. overlap (%) 71%
Genomic Region Intergenic
Retrocopy Summary CNEP1R1P1, located on chrX:103650524-103652132, is a retrocopy of the parental gene CNEP1R1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CNEP1R1
Full Name CTD nuclear envelope phosphatase 1 regulatory subunit 1
Also known as C16orf69|NEP1-R1|NEP1R1|TMEM188|TMP125
Coordinate chr16:50025225-50037081
Strand +
Gene summary This gene encodes a transmembrane protein that belongs to the Tmemb_18A family. A similar protein in yeast is a component of an endoplasmic reticulum-associated protein phosphatase complex and is thought to play a role in the synthesis of triacylglycerol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CNEP1R1P2
Bonobo Pan paniscus CNEP1R1P2
Gorilla Gorilla gorilla CNEP1R1P2
Orangutan Pongo abelii CNEP1R1P2
Green monkey Chlorocebus sabaeus CNEP1R1P2
Crab-eating macaque Macaca fascicularis CNEP1R1P2
Rhesus Macaca mulatta CNEP1R1P2
Baboon Papio anubis CNEP1R1P2
Golden snub-nosed monkey Rhinopithecus roxellana CNEP1R1P1
Marmoset Callithrix jacchus CNEP1R1P1
Gibbon Nomascus leucogenys Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CNEP1R1P1
GGCGGTGACCTGAGCTGCCACCTGACATGAATTTGCTGGAGCAGGCAGAAGAGCTCAAGGCTTTTGAGAGGAGACTTACTGAATATATTCATTGTTTGCAACCTGCTACTGGATGTTGGAGAATGCTTCTTCTAGTGGTATCTGTCTGTACGCTACTGGTGCCTGGAACTGGTTGATAGATCCAGAGACACAAAAGGTGTCCTTCTTCACATCATTATGGAATCATCCATTTTTTACCATTAGCTATATCACTCTAATAGGCTTGTTCTTTGCTGGAATACACAAGAGAGTAGTTGCACCATCAATTATAGCTGCTCAACGTCAAACGATATTAGCAGAATACAATATGTCTTGTGATGATACAGGAAAACTAATTTTGAAACCTAGGCCTCATGTTCAATGCCAATCTTCACTAATTGCTATTGGACGTAAAACAGCCCTTCTTCGAATAAGTGATACAGCAAAAAGCCATAAAGGATTCCTTTTGCAGTTGGATATGTAAAGGTCATAGCAACAACTGACAAGATGTGTGCAATATTTACCCAGATTATCTTGGTGATGATGATTCACATTATCAGTGCTTTGGTACTTTTTATTACCTGTGTTTCAGTATTAGTGTCACTTTATTACTTCAGATCCTTCAAAGATTTTTGCAGATAAAGTGTGTATATATGTTATGAAGCTCAACTTAAAAATAGAACCTCATTCAGTTTTTATAATGTACTTTTGCAAACTACTGTAAATAGCAAATCAATGCCAATGGTAAACAAAGAGGAAAATGTTGTGTGGTCTTTGTTCTCCTGCACCAGTACTTCAGGAACATCTGCTTGCCATCCCCACAGCTCTTTAAAACTGGCTATTATGTGTGCCTTTCATTCTTACACTTTTAATCATACTGTAGGAAAAACATTGGATTCAGCTTAGACTGAGGAAAACTCCTCTCCATAATGTTGTAAGAAATTATAGGTGTTTTGATAAACACTTTTTGTTAAACCAGATATTGAACTCCAGCAACTATTGTGGTTATATTTTTCAGTTCATTGTTTTCATTGAGTGCTAAATATCCTTAATATTTTAAAATAATTTTTTAAATACCCCAAAGGCTTGTGAATATACAAGTCTACTTATAAATTATGTATTGTCTGGGACTTTGATAGACATTGTTTTAGATAACTGGATTTTACGCTGTGGTAGACAGACTGTGACGTTAGTGTTGCACAGGTGTAATTGATCATCCTACGCCATCACCAGAATAACATGGGAGTGGTGCCACAAACTAGAGTCTACAATTCTCACTGTTTAGAGAGTGTTAATGACATGCCATGTATGCATAATAACTACATGTACTATATTAACCCTTAAAATTAAGCTATTGGGATGGCTATAAATACTTTAAAGTACTGGAAGTGCTTTTACCTGTTTATTAGAAGGTTTTGAAAAGGTTTAAATTATTTCATGAGCAATCTTTTAAATTTCATTTAACGTAAAACTGAAAATTCAATAACAGGATAAAAAACTTTGTAACAAGGCTTAAGGCTTTCACGTAAATGTGTTGATCTTAGCTTTCACATGGATAAAATTTAATTCTTTGAACTGTAGCAATAAAACA
>NM_001281789.2
AGAGGTGGGAGTTGGCGCTGCGGGCCGGGCGGGGGCCGCGGAAGCTGCGATGCGGACAGGGCAGCGGCGGTGACCCGAGCTGCCGCCCGACATGAACTCGCTGGAGCAGGCGGAAGATCTCAAGGCTTTTGAGAGGAGACTTACTGAATATATTCATTGTTTGCAACCTGCTACTGGACGCTGGAGAATGCTTCTTATAGTGGTATCTGTCTGTACAGCTACTGGTGCCTGGAACTGGTTAATAGACCCTGAGACACAAAAGGTGTCCTTCTTCACATCATTATGGAATCACCCATTTTTCACCATTAGCTGTATCACTCTAATAGGCTTGTTCTTTGCTGGAATACACAAGAGAGTAGTTGCACCATCAATTATAGCTGCTCGATGTCGAACGGTATTAGCAGAATACAATATGTCTTGTGATGATACAGGAAAACTAATTTTGAAACCTAGGCCTCATGTTCAATGACAATCTTCACTCATTGTTATGGGACTTAAAATAGCCTTTCTTCGAATAAGTGATACAGCAAAAAGCCATAAAGGATTCCTTTTGCGGTTGGATATGTAAAGGTCATAGCAGCAACTGACAAGAAGTGTGCAATATTTACCTGGATTATCTTGATGATGGTGACTCATTATCAGTGCTTTGGTACTTTTGATTACCTGTGTTTCAGTATTAGTGTCACTTTAGTACTTCAGATCCTGCAAATATTTTTGCAGATGAAGTATGTATGTATGTTACTAAGTTAAACTTAGAAACAGAACCTCATTCAGTTTTTATAATGTATTTTTGCAAACTACTGTAAATAGCAAATCAATGCCAATGTTAAACAAAGAGGAAAACGTTGTGTGGACTTTGTTCTCTTGCACCAGTATTTCAGGAACATCTGCTTGCCATCCCCACAGCTCTTTAAAACTGGCTATTATGTGTGCCTTTCATTCTTACATTTCTAATCATACTGCAGGAAAAACATTGGATTCAGCTTAGACTGAGGAAAACTCTCCATTATGTTGTAAGAAATTATAGATGTTTTGAGAGACACTTTTTGTTAAACCAGATATTGAACTCCAGCAACTATTGTGGTTATATTTTTAGTTCATTGTTCTCATTTAATGCTAAATATCCTTTATATTGCTTTAATAAttttcttttttttttttttttttttagacggagtctcgctctgttgccaggctggagggcagtggcacgatcttggctttctgcaacctctgcctcccaggttcaagcgattctcctgcttcagccttctgagtagctgggactacaggcgcatgccaccatgcccagctaatttttttgtatttttagtagagacggggtttcaccacgttggccaggatggtttcgatctcctgacctcgtgatcctcctgcctcatcctcccaaaatgctgggattacaggcataagccaccgtgcctggccTCTTTAATAATTTTTAAAATACCCTAAAGGCTTGTGAATATACAAGTCTACTGATAAATTATGTATTGTCTGGGAATTTGATAGTCATTGTTTTAGATAACTGGATTTTACGCTGTGGTAGACAGGCTGTGACACTAGTGTTGCACAGGTGTAATTGGTCATCCTATGCCTTCACCAGAATAACTTGGGAGTGGTGCCAGAAACTAGAGTCTACAATTCTCACTGTTTAGAGAGTGTTAATGACATACTGTGTATGCATAATAGCCGCATGTACTATAATAGCCCTTAAAATTAAACTATTGGGATTGCTGTAAATATTTTAAAGTACTGGAGGTGCCTTTTACCTGTTTATTAGATTTTGAAAAGGTTTAAATTATTTCATGAGCAATCTTTTAAATTTCATTTAACATAAAGCTGAAAATTCAATAACAGGATAAAAAAGCTTTTTAACAAGGCTGCCATTTAACTTAAATGTGTTCATCTTAGCTTTCACTTGTATAAAATTTGATTCTTTGAACTGCAGCAATAAAACCCTCAGCTCCTAAGAAGTCTTAAGAGGGTATTCTATATATTCTGCTTTGTTTTATTTTCTGTAAATTTTGTAGGTAAATATGTGCATTAAAAATAAATACTTTATATATAA

Publications

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