Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name MYCLP1
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:107272690-107276556  UCSC
Coordinates (hg19) chrX:106515920-106519786  UCSC
Strand +
Parental Sequence NM_001033082.3
Parental seq. overlap 2501 bp
Parental seq. overlap (%) 71.6%
Genomic Region Intergenic
Retrocopy Summary MYCLP1, located on chrX:107272690-107276556, is a retrocopy of the parental gene MYCL. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name MYCL
Full Name MYCL proto-oncogene, bHLH transcription factor
Also known as L-Myc|LMYC|MYCL1|bHLHe38
Coordinate chr1:39895428-39901917
Strand -
Gene summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of inner ear auditory receptor cell differentiation. Located in chromosome and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Bonobo Pan paniscus MYCLP2
Gorilla Gorilla gorilla MYCLP1
Orangutan Pongo abelii MYCLP1
Gibbon Nomascus leucogenys MYCLP1
Green monkey Chlorocebus sabaeus MYCLP1
Crab-eating macaque Macaca fascicularis MYCLP1
Rhesus Macaca mulatta MYCLP1
Baboon Papio anubis MYCLP1
Golden snub-nosed monkey Rhinopithecus roxellana MYCLP1
Chimpanzee Pan troglodytes Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>MYCLP1
CCGCCGCCCTGGGACTTGGGTCCCGCAGCCGGGAACCCAGCCCTCAGCTTTGGTCTCCTGGAACCGTGGCCGGTAGGGTGCGCTGGGGACGAGACGGAATCCCAGGACTACTGGAAAGCTTGGGACGCGAACTACGCCTCCCTCATCCGCCGTGACTGCATGTGGAGCGGCTTCTCCACCCAGGAGCCGCTGGAGAGAGCGGTGAGTGACCTGCTTGCCGTTGGCGCGCCCTCGGGATACTCGCCCAAGGAGTTCGCCACCCCCGACTACACTCCCGAGCTCGAAGCCGGCAACCTAGCGCCCATCTTCCCCTGTTTGTTGGGCGAGCCCAAGATCCAGGCCTGCTCCAGGTCTGAGAGCCCAAGCGACTCCGAGGGTGAAGAAATCGACGTGACAGTAAAGAAGAGGCAGTCTTTGAGTACGCGGAAGCCAGTCATCATCGCGGTGCGTGCAGACCTTCTGGATCCCCGCATGAATCTCTTCCACATCTCCATCCACCAGCAACAGCACAACTATGCTGCCCCTTTTCCTCCAGAAAGCTGCTTCCAAGAAGGGGCTCCAAAGAGGATGCCCCCAAAAGAGGCTCTAGAGAGAGAAGCTCCAGGGGGAAAGGATGATAAGGAAGATGAAGAGATTGTGAGCCTCCCACCTGTAGAAAGTGAGGCTGCCCAGTCCTGCCAGCCCAAACCCATCCATTATGATACTGAGAATTGGACCAAGAAGAAGTACCACAGCTACCTGGAGCGCAAGAGACGGAATGATCAACGTTCGCGGTTCTTGGCCCTGAGGGACGAGGTACCCGCCCTGGCCAGCTGCTCTAGGGTTTCCAAAGTAATGATCCTAGTCAAGGCCACGGAATACTTACATGAACTGGCGGAAGCCGAGGAGAGGATGGCTACGGAGAAAAGGCAGCTCGAATGCCAGCGACGGCAATTGCAGAAAAGAATTGAGTACCTCAGTAGCTACTGACCAAAAAGCCTGACCATTCTGTCTTAAAAAGACACAAGTTTTCTTTTTGATCTCCCTCTCCCCTTTAGTAACTTGTACATTTTTGTTACAGCAGGACACTCTGGACAGTAGATTGCAGAATGCATTGCAGCCAGTGCACAAACAATATAAAGGCTTGCATTCTTGGAAACTTTGAAACCCAGCTCTCTCTCTTCCCTGACTTATGGGAGTGCTTTGTGTTTTCTGGCACCTTTGGCTTCTCAGCAGGCAGCTGACTGAGGAGACTTGGGGTCTTCCTGGCTCACTATCTCCAAAGAAAAGGCTGACAGATGGTATGCAACAGGTGGTGGATGTTGTTGGGGGCTCCAGCCTGGAGGAAATCTCACACTCTACATGAACTTTAGGCTAGGAAAGGATGTCTCTGGGGTGATGCAAGGACAGCTGGGTGTGGACGCTCTCCCTGCGGCTCCATTTTTTTCCAGGAGACACACAAGCTGCCTTGGGTGAAAACAAGCTCAGAGACTTGATCAACGTGGACCATTACCTCACTGTCAGACACTACAGTAGCTGAGGAGTTGGAAACCTTACtatgATGTTGGCTGACCCCCTTCCTCCCACTCTCAATGCTGTGACTCAGAACATTTAAGAGAACTTCGTCTGTAAGTAATTTGTCTTAAAGCCCTCTGGGCTCTCTTCTCTGAGTGAGGGAACTTTCTGTCTTCACAAGGGACTTTGTCTCATTCTGCCTCTGTTATGCAATGGGTTCTACAGCACCCTTTCCCGCAGGTTAGAAATATTTCCCTAAGACACAGGGAAATGGGTCTTAGCCTGGGGCCTGGGGAAAGTTCCCAAGCCCTGGCTCATGAACTCAATCCCTGCCCAGGTGTTTTCTGAGGGGCCCTTGAGGCCCAATCTTTTCTCAAGACAGGTGTGAGGCACCTTAGAAGGGAGAACTGTAACACTTTCTCTTTCGCACCTGCCTCTCATCTCAATCCTTGACTGATGAATTTGAAGTTCTACTAGAACCATGAAAACTTGTTCCTTTCGTGCATCTCCAAGGAGCTTGCTGGCTCTGCAGCCACGCTTGGGCCCTCGCACCAGCCTGCAATGAGTCAGATGTCTGTCACAGAATCTGGGCCTCTCTGAAGTTTTCTGGAGAGCTGTTGGGACTCATCCAGTGCTCCACAACGTGGACTTGCCTCCTGGTGTGTTTTAAAGGATCCTCCAGGAGCTCTGCTTAGCCAATCATCATGATGGACATGATAGATTTTGCCCCAGCTGGACTCTGCAGCTCCACGTGGAATCCAGGTGCTGCCTCCAGTCTGGGAAAGTCACCCAACCCCGCAGTTGTCATGTGGGTAACTTCTGAAACCCCTAAGCCTGTCCTGTGAGAAGGACCAGCCTCTCCAGAACTCTGCCTAGGACAGCAGGTGCCTGCTTGGAAGTTGGGAGGATGGGGAGTGGTAAGTCCTATTATATGTGGCTCTGGAACACCAGCTGCTACTTCCAAATCTATTGTCCATAATGGTTTCTTTCTGAGGTTGCTTCTTGCCCTCAGAGAACTCCAGGGGATGTTTGGAAATAGCCTCTTTACCCTTCTGGAGCATGGTTTACAAGAGCCAGCTGACTTTTGAAACTGTCTATGGAACAGGTTAAGTGTAGGTTACTGATGTTTCACCTGAATACCTTGTATTTTATAAGCTGCTGTTTGGTATTATACTGGGGGAGAGTATTTTTTATATTgTATATTGTATTTTTGTATGCCTTTTGCAAAGTGGTGTTAACTCTTTCTGTACAAGAAAAAAAAAACCTCTTGGGTAATTCTGTTAAAAGGGTCTGAATAGCTTGTGTTTTATAAGCTGCTGTTTGGTATTACACTGAGGGGGAGTATTTTTTACATTGTATTTTTGTATGCCTTTGGCAAAGTGGTGTTAACTCTTTTTGTACAAGAAAAAAATACTCTTGGGTAATTCTGTTAAAAGGGTCTAAATAACTTGTGTTTTATCAGCTGCTGTTTGGTATACTGGGGGGGAGTATTTTTTATATTGTATTTTTGTATGCCGTTTGCAAAGCAGTGTTAACTCTTTTTGTTCAAGAAAAAAACCTCTTGGGAAATTCCGTTAAAAGGGTCTGATTTATTTTGAAAAGCACGTTTACCTGAAATTTTGTATTTAGTTTTGATTTCTGATTGCCTGATTGTAAAATGTTGCCTTTTGGGACATCTTCTAATAAAAGTTTCATCAAACA
>NM_001033082.3
GAGTGCGGGCCGCGCTCTCGGCGGCGCGCATGTGCGTGTGTGCTGGCTGCCGGGCTGCCCCGAGCCGGCGGGGAGCCGGTCCGCTCCAGGTGGCGGGCGGCTGGAGCGAGGGAGCGGACATGgactacgactcgtaccagcactatttctacgactatgactgcgGGGAGGATTTCTACCGCTCCACGGCGCCCAGCGAGGACATCTGGAAGAAATTCGAGCTGGTGCCATCGCCCCCCACGTCGCCGCCCTGGGGCTTGGGTCCCGGCGCAGGGGACCCGGCCCCCGGGATTGGTCCCCCGGAGCCGTGGCCCGGAGGGTGCACCGGAGACGAAGCGGAATCCCGGGGCCACTCGAAAGGCTGGGGCAGGAACTACGCCTCCATCATACGCCGTGACTGCATGTGGAGCGGCTTCTCGGCCCGGGAACGGCTGGAGAGAGCTGTGAGCGACCGGCTCGCTCCTGGCGCGCCCCGGGGGAACCCGCCCAAGGCGTCCGCCGCCCCGGACTGCACTCCCAGCCTCGAAGCCGGCAACCCGGCGCCCGCCGCCCCCTGTCCGCTGGGCGAACCCAAGACCCAGGCCTGCTCCGGGTCCGAGAGCCCAAGCGACTCGGAGAATGAAGAAATTGATGTTGTGACAGTAGAGAAGAGGCAGTCTCTGGGTATTCGGAAGCCGGTCACCATCACGGTGCGAGCAGACCCCCTGGATCCCTGCATGAAGCATTTCCACATCTCCATCCATCAGCAACAGCACAACTATGCTGCCCGTTTTCCTCCAGAAAGCTGCTCCCAAGAAGAGGCTTCAGAGAGGGGTCCCCAAGAAGAGGTTCTGGAGAGAGATGCTGCAGGGGAAAAGGAAGATGAGGAGGATGAAGAGATTGTGAGTCCCCCACCTGTAGAAAGTGAGGCTGCCCAGTCCTGCCACCCCAAACCTGTCAGTTCTGATACTGAGGATGTGACCAAGAGGAAGAATCACAACTTCCTGGAGCGCAAGAGGCGGAATGACCTGCGTTCGCGATTCTTGGCGCTGAGGGACCAGGTGCCCACCCTGGCCAGCTGCTCCAAGGCCCCCAAAGTAGTGATCCTAAGCAAGGCCTTGGAATACTTGCAAGCCCTGGTGGGGGCTGAGAAGAGGATGGCTACAGAGAAAAGACAGCTCCGATGCCGGCAGCAGCAGTTGCAGAAAAGAATTGCATACCTCACTGGCTACTAACTGACCAAAAAGCCTGACAGTTCTGTCTTACGAAGACACAAGTTTATTTTTTAACCTCCCTCTCCCCTTTAGTAATTTGCACATTTTGGTTATGGTGGGACAGTCTGGACAGTAGATCCCAGAATGCATTGCAGCCGGTGCACACACAATAAAGGCTTGCATTCTTGGAAACCTTGAAACCCAGCTCTCCCTCTTCCCTGACTCATGGGAGTGCTGTATGTTCTCTGGCGCCTTTGGCTTCCCAGCAGGCAGCTGACTGAGGAGCCTTGGGGTCTGCCTAGCTCACTAGCTCTGAAGAAAAGGCTGACAGATGCTATGCAACAGGTGGTGGATGTTGTCAGGGGCTCCAGCCTGCATGAAATCTCACACTCTGCATGAGCTTTAGGCTAGGAAAGGATGCTCCCAACTGGTGTCTCTGGGGTGATGCAAGGACAGCTGGGCCTGGATGCTCTCCCTGAGGCTCCTTTTTCCAGAAGACACACGAGCTGTCTTGGGTGAAGACAAGCTTGCAGACTTGATCAACATTGACCATTACCTCACTGTCAGACACTTTACAGTAGCCAAGGAGTTGGAAACCTTTATATATTATGATGTTAGCTGACCCCCTTCCTCCCACTCCCAATGCTGCGACCCTGGGAACACTTAAAAAGCTTGGCCTCTAGATTCTTTGTCTCAGAGCCCTCTGGGCTCTCTCCTCTGAGGGAGGGACCTTTCTTTCCTCACAAGGGACTTTTTTGTTCCATTATGCCTTGTTATGCAATGGGCTCTACAGCACCCTTTCCCACAGGTCAGAAATATTTCCCCAAGACACAGGGAAATCGGTCCTAGCCTGGGGCCTGGGGATAGCTTGGAGTCCTGGCCCATGAACTTGATCCCTGCCCAGGTGTTTTCCGAGGGGCACTTGAGGCCCAGTCTTTTCTCAAGGCAGGTGTAAGACACCTCAGAGGGAGAACTGTACTGCTGCCTCTTTCCCACCTGCCTCATCTCAATCCTTGAGCGGCAAGTTTGAAGTTCTTCTGGAACCATGCAAATCTGTCCTCCTCATGCAATTCCAAGGAGCTTGCTGGCTCTGCAGCCACCCTTGGGCCCCTTCCAGCCTGCCATGAATCAGATATCTTTCCCAGAATCTGGGCGTTTCTGAAGTTTTGGGGAGAGCTGTTGGGACTCATCCAGTGCTCCAGAAGGTGGACTTGCTTCTGGTGGGTTTTAAAGGAGCCTCCAGGAGATATGCTTAGCCAACCATGATGGATTTTACCCCAGCTGGACTCGGCAGCTCCAAGTGGAATCCACGTGCAGCTTCTAGTCTGGGAAAGTCACCCAACCTAGCAGTTGTCATGTGGGTAACCTCAGGCACCTCTAAGCCTGTCCTGGAAGAAGGACCAGCAGCCCCTCCAGAACTCTGCCCAGGACAGCAGGTGCCTGCTGGCTCTGGGTTTGGAAGTTGGGGTGGGTAGGGGGTGGTAAGTACTATATATGGCTCTGGAAAACCAGCTGCTACTTCCAAATCTATTGTCCATAATGGTTTCTTTCTGAGGTTGCTTCTTGGCCTCAGAGGACCCCAGGGGATGTTTGGAAATAGCCTCTCTACCCTTCTGGAGCATGGTTTACAAAAGCCAGCTGACTTCTGGAATTGTCTATGGAGGACAGTTTGGGTGTAGGTTACTGATGTCTCAACTGAATAGCTTGTGTTTTATAAGCTGCTGTTGGCTATTATGCTGGGGGAGTCTTTTTTTTTTATATTGTATTTTTGTATGCCTTTTGCAAAGTGGTGTTAACTGTTTTTGTACAAGGAAAAAAACTCTTGGGGCAATTTCCTGTTGCAAGGGTCTGATTTATTTTGAAAGGCAAGTTCACCTGAAATTTTGTATTTAGTTGTGATTACTGATTGCCTGATTTTAAAATGTTGCCTTCTGGGACATCTTCTAATAAAAGATTTCTCAAACA

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