Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TMEM230P1
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr20). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:107939334-107939661  UCSC
Coordinates (T2T) chrX:106376428-106376755  UCSC
Coordinates (hg19) chrX:107182564-107182891  UCSC
Strand -
Parental Sequence XM_017027836.2
Parental seq. overlap 295 bp
Parental seq. overlap (%) 19.5%
Genomic Region Intergenic
Retrocopy Summary TMEM230P1, located on chrX:107939334-107939661, is a retrocopy of the parental gene TMEM230. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TMEM230
Full Name transmembrane protein 230
Also known as C20orf30|HSPC274|dJ1116H23.2.1
Coordinate chr20:5068375-5113091
Strand -
Gene summary This gene encodes a multi-pass transmembrane protein that belongs to the TMEM134/TMEM230 protein family. The encoded protein localizes to secretory and recycling vesicle in the neuron and may be involved in synaptic vesicles trafficking and recycling. Mutations in this gene may be linked to familial Parkinson's disease. [provided by RefSeq, Mar 2017]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TMEM230P4
Bonobo Pan paniscus TMEM230P4
Gorilla Gorilla gorilla TMEM230P4
Orangutan Pongo abelii TMEM230P3
Gibbon Nomascus leucogenys TMEM230P3
Green monkey Chlorocebus sabaeus TMEM230P4
Crab-eating macaque Macaca fascicularis TMEM230P4
Rhesus Macaca mulatta TMEM230P4
Baboon Papio anubis TMEM230P4
Golden snub-nosed monkey Rhinopithecus roxellana TMEM230P1
Marmoset Callithrix jacchus TMEM230P3
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TMEM230P1
GTAGCTGTGTCAGTGTGTTATGATGCCCTCCCACATCAACCTGGCTGGAATCTCCGTAGTAAAGTGATATACTCAAGGCTCTCCAGCACAGATGATGGCTACACTGACCTCCAGTTTAAGAAAAGCCCTCCTAAGATCCCTTATAAGGCCACTGCACTTGCCACTGTGCTCTTTTTCGATTGGTGCCTTTCTCATTATCATAGGCTCACCTTCTGGCTACATCAGCAAAGCGGGGGCAGACTGGGCAGTTCCAGTCCTGATCATTGACATTCTGGTATTCCTGCCCAGATTTTACCACCTGCACAGAGCCTACTATGCATCCAAAGGA
>XM_017027836.2
ATGCAACCTTGGGCGCTGCCAACCGTGGGCGAGCTCTGGGTGTGCGGGCGGCCTGGCGCGGCGCTCCGatggagtctagttctgtcgcccaggctggagcccagtggtgtgatctcagctcactgcaatctccacctcctggcttcaagcgattcttctgcttcagcctcccgagtagCTGTGTCAGCGTGTTATGATGCCGTCCCGTACCAACCTGGCTACTGGAATCCCCAGTAGTAAAGTGAAATATTCAAGGCTCTCCAGCACAGACGATGGCTACATTGACCTTCAGTTTAAGAAAACCCCTCCTAAGATCCCTTATAAGGCCATCGCACTTGCCACTGTGCTGTTTTTGATTGGCGCCTTTCTCATTATTATAGGCTCCCTCCTGCTGTCAGGCTACATCAGCAAAGGGGGGGCAGACCGGGCCGTTCCAGTGCTGATCATTGGCATTCTGGTGTTCCTACCCGGATTTTACCACCTGCGCATCGCTTACTATGCATCCAAAGGCTACCGTGGTTACTCCTATGATGACATTCCAGACTTTGATGACTAGCACCCACCCCATAGCTGAGGAGGAGTCACAGTGGAACTGTCCCAGCTTTAAGATATCTAGCAGAAACTATAGCTGAGGACTAAGGAATTCTGCAGCTTGCAGATGTTTAAGAAAATAATGGCCAGATTTTTTGGGTCCTTCCCAAAGATGTTAAGTGAACCTACAGTTAGCTAATTAGGACAAGCTCTATTTTTCATCCCTGGGCCCTGACAAGTTTTTCCACAGGAATATGTATCATGGAAGAATAGAGGTTATTCTGTAATGGAAAAGTGTTGCCTGCCACCACCCTCTGTAGAGCTGAGCATTTCTTTTAAATAGTCTTCATTGCCAATTTGTTCTTGTAGCAAATGGAACAATGTGGTATGGCTAATTTCTTATTATTAAGTAATTTATTTTAAAAATATCTGAGTATATTATCCTGTACACTTATCCCTACCTTCATGTTCCAGTGGAAGACCTTAGTAAAATCAAAGATCAGTGAGTTCATCTGTAATATTTTTTTTACTTGCTTTCTTACTGACAGCAACCAGGAATTTTTTTATCCTGCAGAGCAAGTTTTCAAAATGTAAATACTTCCTCTGTTTAACAGTCCTTGGACCATTCTGATCCAGTTCACCAGTAGGTTGGACAGCATATAATTTGCATCATTTTGTCCCTTGTAAATCAAGATGTTCTGCAGATTATTCCTTTAACGGCCGGACTTTTGGCTGTTTCCTAATGAAACATGTAGTGGTTATTATTTAGAGTTTATAGCCGTATTGCTAGCACCTTGTAGTATGTCATCATTCTGCTCATGATTCCAAGGATCAGCCTGGATGCCTAGAGGACTAGATCACCTTAGTTTGATTCTATTTTTTAGCTTGCAAAAAGTGACTTATATTCCAAAGAAATTAAAATGTTGAAATCCAAATCCTAGAAATAAAATGAGTTAACTTCAAACATTTCAGAAAA

Publications

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