Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PRPF4BP1
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr6). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:116748015-116748877  UCSC
Coordinates (T2T) chrX:115124485-115125347  UCSC
Coordinates (hg19) chrX:115881983-115882845  UCSC
Strand -
Parental Sequence XM_017011416.2
Parental seq. overlap 759 bp
Parental seq. overlap (%) 15.1%
Genomic Region Intergenic
Retrocopy Summary PRPF4BP1, located on chrX:116748015-116748877, is a retrocopy of the parental gene PRPF4B. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PRPF4B
Full Name pre-mRNA processing factor 4B
Also known as PR4H|PRP4|PRP4H|PRP4K|dJ1013A10.1
Coordinate chr6:4021300-4064983
Strand +
Gene summary Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs). [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PRPF4BP2
Bonobo Pan paniscus PRPF4BP2
Orangutan Pongo abelii PRPF4BP2
Crab-eating macaque Macaca fascicularis PRPF4BP2
Rhesus Macaca mulatta PRPF4BP2
Baboon Papio anubis PRPF4BP2
Golden snub-nosed monkey Rhinopithecus roxellana PRPF4BP1
Gorilla Gorilla gorilla Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PRPF4BP1
GTATTCAAGGATCAGCATTTTGATCAAAATCTCAACTTCAGGTATATAGAAATTGATAAAGTAACAGAGAGGGAGAAAGTTACTGTTATAAGCACCATTAATCCAACTAAGGACCTGTTGGCTGACTTGATTGGGTGCCAGAGACTTCCTGAAGACCAACGTAAGAAAGTACACCAGCTAAAGGACTTGTTGGACCAGATTCTGATGTTGGATCCAGCTAAACGAATTAGCATCAACCAGGCCCTACAGCATGCCTTCATCCAGGAAAAAATTTAAACAAGATGAAGAAACTCCAAGGGCTTGAGTAAATATAAAGACTGAAGAAATTTCACAGCAGTTTATTAATGTGTGTGTGTGCGGGCCACAGCAGCATGCCATTGGTGTAGTCAGTGATGAAAGGGGTCTGTTCCTTCTTGAGCCTGCTGCAGGGATGGTCTCCTTTTAAAGCAGTTGTGTGCAGCATTCAGTACACTGAAGAGAGAAAGGAAAATGGGGCACAGGCCATTCGATGCCTTCTCCAAGGAGTCTGACTTGCTGAGACACCAGCTTCACCTTCTTAACAAGGTGCAGCTCAGTGGAAGATGATGACAACCAGAAGATGTGAGCTAAGGGTAAGGGACTGTTCTGAAGAACTTTTCCATTTAGTGATCAAGATATGGAAGCTGATTTATGAAAATACTCAGTGTATATTCTAATTATTTGTGGTACCATTTGAATTGTAACTTGCATTTTAGCAGTGCATGTTTGTAATTGACTTACTGGGAAACTGATTAAAATACACCTCTTATTAA
>XM_017011416.2
ACATGCGCGGCAGCTCTTTTCCTTCTTCCTCCACTTCCCCTACCCTCCACCGTCCGGGAgccgccgccaccgccgccgAGGAGTCAGGAAGTTCAAGATGGCCGCCGCGGAGACCCAGTCGCTACGGGAGCAGCCAGAGATGGAAGATGCTAATTCTGAAAAGAGTATAAATGAAGAAAATGGAGAAGTATCAGAAGACCAGTCTCAAAATAAGCACAGTCGTCACAAAaaaaagaagcataaacacagaagtaaacataagaaacataaacattcctcagaagaagacaaggataaaaaacataaacataagcataaacataaGAAACACAAAAGAAAAGAGATTATTGATGCTTCTGATAAAGAGGGTATGTCTCCAGCAAAAAGAACTAAACTTGATGATTTAGCTTTGCTAGAAGACTTGGAAAAACAGAGAGCCTTGATTAAGGCCGAACTTGATAATGAGTTAATGGAAGGAAAGGTCCAGTCTGGTATGGGGCTCATTTTGCAAGGTTATGAGTCTGGCTCTGAAGAAGAGGGGGAAATTCATGAAAAGGCAAGAAATGGAAATAGGTCTAGTACTAGATCTTCAAGTACAAAGGGGAAACTTGAACTTGTGGACAATAAAATTACTACAAAGAAACGAAGTAAAAGCAGATCCAAAGAACGGACTAGACATAGGTCTGATAAAAAGAAAAGTAAGGGGGGTATTGAAATCGTTAAAGAGAAAACAACTAGGAGCAAGTCAAAGGAGAGGAAAAAATCTAAAAGCCCATCCAAAAGAAGTAAGTCTCAAGATCAAGCAAGGAAATCAAAATCCCCTACCCTTAGAAGGCGATCTCAAGAGAAAATTGGTAAGGCCAGATCTCCTACTGATGATAAGGTTAAAATTGAAGATAAAAGTAAATCAAAAGATAGGAAAAAATCCCCAATTATAAATGAAAGTAGAAGTCGCGATCGAGGTAAAAAATCCAGATCCCCAGTTGATTTAAGAGGTAAATCCAAAGACAGAAGGTCACGGTCCAAAGAGAGAAAATCAAAACGGTCTGAAACTGATAAAGAAAAGAAGCCAATTAAATCTCCCTCTAAAGATGCTTCATCTGGGAAAGAAAATAGGTCACCCAGCAGAAGACCTGGTCGTAGTCCTAAAAGAAGAAGTTTGTCTCCAAAACCACGTGATAAATCAAGAAGAAGCAGGTCTCCACTTTTGAATGATAGAAGATCTAAGCAGAGCAAATCCCCCTCGCGGACACTGTCTCCTGGGAGAAGAGCCAAGAGCCGATCCTTAGAAAGAAAACGACGAGAACCAGAGAGGAGACGACTTTCTTCTCCAAGAACACGACCTCGAGATGATATCCTCAGTAGACGTGAAAGATCAAAAGATGCCAGCCCCATCAATAGATGGTCTCCAACCCGAAGAAGAAGTAGATCTCCCATTAGAAGGAGGTCTCGTTCCCCACTCAGACGTAGCAGGTCTCCAAGAAGAAGAAGCAGATCTCCTCGGAGAAGGGACAGAGGTCGGAGGAGCAGATCACGCTTGCGAAGGCGGTCTCGATCACGCGGTGGTCGTAGACGAAGGAGCAGAAGCAAAGTAAAGGAAGATAAATTTAAAGGAAGTCTTTCTGAAGGAATGAAAGTTGAGCAGGAATCTTCGTCTGATGATAACCTTGAAGACTTTGATGTAGAGGAAGAAGATGAAGAAGCCCTAATAGAACAGAGAAGAATCCAAAGGCAGGCAATTGTTCAGAAATATAAATACCTTGCTGAAGATAGCAACATGTCTGTGCCATCTGAACCAAGCAGCCCCCAGAGCAGTACGAGAACACGATCACCATCTCCAGATGACATTCTGGAGCGAGTAGCTGCTGATGTTAAAGAGTATGAACGGGAAAATGTTGATACATTTGAGGCCTCAGTGAAAGCCAAGCATAATCTAATGACAGTTGAACAGAATAATGGTTCATCTCAGAAGAAGTTGTTGGCACCTGATATGTTTACAGAATCTGATGATATGTTTGCTGCGTATTTTGATAGTGCTCGTCTTCGGGCCGCTGGCATTGGAAAAGATTTCAAAGAGAATCCCAACCTCAGAGATAACTGGACCGATGCAGAAGGCTATTATCGTGTGAACATAGGTGAAGTCCTAGATAAACGTTACAATGTGTATGGCTACACTGGGCAAGGTGTATTCAGTAATGTTGTACGAGCCAGAGATAATGCAAGAGCCAACCAAGAAGTGGCTGTAAAGATCATCAGAAACAATGAGCTCATGCAAAAGACTGGTTTAAAAGAATTAGAGTTCTTGAAAAAACTTAATGATGCTGATCCTGATGACAAATTTCATTGTCTGAGACTCTTCAGGCACTTCTATCACAAGCAGCATCTTTGTCTGGTATTCGAGCCTCTCAGCATGAACTTACGAGAGGTGTTAAAAAAATATGGTAAAGATGTTGGTCTTCATATTAAAGCTGTAAGATCCTATAGTCAGCAGTTGTTCCTGGCATTGAAACTCCTTAAAAGATGCAATATCCTACATGCAGATATCAAGCCAGACAATATCCTGGTTAATGAATCCAAAACTATTTTAAAGCTTTGCGATTTTGGGTCGGCTTCACATGTTGCGGATAATGACATAACACCTTATCTTGTCAGTAGATTTTATCGTGCTCCTGAAATCATTATAGGTAAAAGCTATGACTATGGTATAGATATGTGGTCTGTAGGTTGCACCTTATACGAACTCTATACTGGAAAAATTTTATTCCCTGGCAAAACCAATAACCATATGCTGAAGCTTGCAATGGATCTCAAAGGAAAGATGCCAAATAAGATGATTCGAAAAGGTGTGTTCAAAGATCAGCATTTTGATCAAAATCTCAACTTCATGTACATAGAAGTTGATAAAGTAACAGAGAGGGAGAAAGTTACTGTTATGAGCACCATTAATCCAACTAAGGACCTGTTGGCTGACTTGATTGGGTGCCAGAGACTTCCTGAAGACCAACGTAAGAAAGTACACCAGCTAAAGGACTTGTTGGACCAGATTCTGATGTTGGACCCAGCTAAACGAATTAGCATCAACCAGGCCCTACAGCACGCCTTCATCCAGGAAAAAATTTAAACAAGATGAAGAAACTCCAAGGGTTTGAGTAAATACAAAGACTGAAGAAATTTCACAGCAGTTTATTAATGTATATAAACTTATAAATATTTCTCCAGCAAATTTGAGGAAGCATGATATATTTGAATTAACACCAAGGGTGATATTTCTTTTAGAGATGTTAGTTAATCTGTTTTGTGTCTTACGTGAAATTTCACTGTAGACTGTTTTAAATTGCCAAGACTGCACAAAATTACAGTGCTAATGTATATGGTTGCAGTTCACATAAAGACAAAAGCATCTGTTATGAAATGAGTAGTAATATTGGGTGGTTGATTTGTTCTTAGCAGACTTGGCTTCATTTTGGTCTTGAGATAAAATGGCCAGCATAAATGCTGTTTATATTCACGTTTTCCTAGGTGTGTGTGTGCAGGCCACAGCAGCATGCCCTTGGTGTAGTCAGTGCCGAAAGGGGTCTGTTCCTTCTTGAGCCTGCCTGCAGGGATGGTCTCCTTTTAAAGCAGGTTGTGTGCAGCATTCAGTACACTGAAGGTAAGCTAAACCATCAACATCTCTGGTGTTTTAAGATGTTATTTTATTGGAACAACTGACAAATGAGGGATGTTAGCTTTGTGGCAGAATTCCCTGCATGTGTGATAACTGATCTTGTTTTATTTTTTGGCATTGCAACTGTGGCATAGTTACAATTTCTGTTTGTTCATCACATTTAAAATTGGAAGAGAACGCGCTTGATGGATAGAGCGCCTTCAGTGTACTGTTTCTTATTAACTTTACTTTTTTTAAATCAACTTGCTATAGACTTTATATACATTTTGTTAAATATAGTTCCTAGTGACATAGAAACGATGCGTAGTTTTCATTTACTAATTACAAATGTTGAGGCCTAATTCTGAAAGTCCTCATATTTAAAGGCTAGACAACGTAATGAAATTTTTAACTATTTGTATGTCATTTTGAAAGTGTACTGCTTTATGGTAAAAGTGTTTTTCATTTGTTCATTGTTTTCATTATTTGTGATCATGTTGTCTTTCAATACAGGCATAAACCTTCCACTCTTGAACAAAGCAGCTGCTTTTTAAAAGCGGTAATTGCTTCTTTACCTTTTATTTCTTTTGTAAATGAAGCTTTTCTTTAAGAATGTGACTTTAAAGTGTTGTCTATTGCATAAAACAGTTGACACTCACTTATTGTAAAGTGAAGATTGTTCTACTGCATGTGAAGTGGACCATGCAGATTTCTGTATGTTCTCAGTATGCATCACTAGATAATAAAGTCTTTTGTGAACAAGGCATTTGTAGCCATTTTTAAAAGTTTTTGTCTTCAGTGCTGGTAAGTCAGGTAAACCATAAATAGTTAAAAGCAACCTTTTGTTTTTTTCCTGAAAGTTTTTAATTGAAAGTATTATTAGTTAAAGATGTAAACCTAGCCAAAATTACCAGTTTATTAATAATTAGGATCCTAATTATTTCAAAAAATCCTACAAATATTGTCAGCTTTCAGTGTAGTGAGATTATTCCTGTAGGTTATGGGGTATAATTCAGGATTTAACTAATGTTTCTGCTATTTTCTCACTTTTCCTTTTGATGGTGCGGAAAGAGAAAAAGGAAAACGGGGCACAGGCCATTCGACGCCTTCTCCAAGGGGTCTGATTTGCTGAGACACCAGCTTCACCTTCTTAACAAGGTGCAGCTCAGTGGAAGATGATGACAACCAGAAGACATGAGCTAAGGGTAAGGGACTGTTCTGAAGAACCTTTCCATTTAGTGATCAAGATATGGAAGCTGATTTCTGAAAATGCTCAGTGTGTACTCTAATTATTTATGGTACCATTTGAATTGTAACTTGCATTTTAGCAGTGCATGTTTCTAATTGACTTACTGGGAAACTGAATAAAATATGCCTCTTATTATCA

Publications

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