Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PNPLA10P
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:127390958-127393086  UCSC
Coordinates (T2T) chrX:125704531-125706659  UCSC
Coordinates (hg19) chrX:126524940-126527068  UCSC
Strand +
Parental Sequence NM_001256007.3
Parental seq. overlap 1780 bp
Parental seq. overlap (%) 38.4%
Genomic Region Intergenic
Retrocopy Summary PNPLA10P, located on chrX:127390958-127393086, is a retrocopy of the parental gene PNPLA8. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PNPLA8
Full Name patatin like phospholipase domain containing 8
Also known as IPLA2-2|IPLA2G|MMLA|PNPLA-gamma|iPLA2gamma
Coordinate chr7:108470417-108528178
Strand -
Gene summary This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. Mutations in this gene have been associated with mitochondrial myopathy with lactic acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2015]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PNPLA8P1
Bonobo Pan paniscus PNPLA8P1
Gorilla Gorilla gorilla PNPLA8P1
Orangutan Pongo abelii PNPLA8P1
Gibbon Nomascus leucogenys PNPLA8P1
Rhesus Macaca mulatta PNPLA8P1
Golden snub-nosed monkey Rhinopithecus roxellana PNPLA8P1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PNPLA10P
aTTCCAGGACATATCAGAACTTGAAGGTAAGCAGGTTGAAGAAGGGAAATTAAGTTCTCCAGATCTTGGCATGCTGACTGATAAGTCAGGCTCAGAATCTTCTTTAGATACTGTGGAAAATCCTTCAAATCCTATTGCAATACTTGAAGTTCTTCTAGTTTCAACTAAAGTATTACTAACTTTCTTTTTCATCCCAGTGAAACTGTATAATCTTTTGTAGGTGGAATATTGGTGGACTTGTCCCCAAGTTAAATTATGATTTAAAGAGACACTTAGAAAAAGAGGAAAAGCCTACTAAAACTGAGCAGGCTATCAGCAAAGACAAAAATGCAGAGAAGAACAACCGTTTATCTCTTCAGGGAGAAATTATTATTGCAATTATATTGATAACAGAACCTGGGTGTTAGTTCAGGTATTAAGAAAAACAACTGACCTGAAGTTCTGTATTACTGGGGTTGAAGAACTGAATTTTCATCATCTAGAATATATTGAAGGAAATGAGTGTCTGTTAAAGAAAGAATTATTCCATATTTATTCTGGCTGAGATAAATTAAAGGTGAAACACTTTAGGCTGCACTTAGATAATTTTCGGCTTTAATTGCCTACGTGCATCCAGTGAAAGGGAGAGGAATCCCAATTTTCATAATTGAAGATGGAGGAACAAGTTATGTGGTTGCTCTGCAGATACTATGCAAATTAGTTGAACTAACTCAGAAACCAGTTGATCAGCCCTTTGATTACATTTGTGGTGTGAGCACAGGTGCCATATTAGCTTTCATGTCGGGATTTTTTCATATGTCCTTGGATGAATGCGAGAAACTATAAAACATTAGGTTCAGACGTATTTTCACAAAATTTCATTGTTGGAAAAGTTAAAATGAGTTGGAGCCATGCATTTTATAGAAGTCAAAGGTGGGAAAAAATTCTGAAAAATAGAATGGGATTTACGCTATTGATGGCAACAGCAAGAAACCCCACATGCCTTAAGGTAACTGCCATAAGTACCATAGTAAACAGAGGGATAACACCAAAATAATTTGATGTTTTAGAAACTATGGTGCTTTAGAAACTATAATTTGTTGTTTCTAAACATAGAAACTATGACCATTTTGCTGGAATCAACTGTCATTTCAGAGGTTCTCAGTATAAAATGTGGCAGGCCATTAGAGCCTCATCTGCTGCTCCAGGCTACTTTGCAGAATACACATTGGGAAATGATCTTCATCAAGGCGGAGGTTTGCTTCTGAATAACTATTTGGCATTAGCAATGCATGAGTATAAATGTCATTGGCCGGATATCCCATTAGAGTGCACAGTATGCCTGGGCACTGGACATTCGGAGAGTGACATGAAAAACACTGTGATACACACAAGCTTGAAAACCAAACTTTCTAATGTTATCAACAGTGCTACAGATATAGAAGCAGTCTGTATAATGCTTGATGTTCTGTTACCTCCTGACACCTATTTTATATTCAATCCTGAAATGTGTGAAAACAACCCTAGATGAAAGTCAAAATGAAAAGCTGGATCAGCTGAAGTTAGAAGGGTTGAAATACATAGAAAAAAATGAAAAAATTTAAAAAGTTGCAAAAATATTAAGTCTAGAAAATATAACTCTGAACAGAATTAATGATGAGATATAATTGAAAACAAACATGTATGAAGGCCTGCTATTCTTTTTAAAGTTGCAATGAGTATATGCTTATGTTCTGATAAATGAAGTCCTGCTCAGAAGATTCACCAAAGTCAATAGGAAATGTGGGGTTCAACATCAGTTACATTTGAAATAATTATGAATTCTAGAGAATCCTGAAGAAGACTGTGCTTCCACCAGTTTGCACAGCATAGATAATATGCTTGGTTGCATAATTCATATGAGAATTAGGTTTTTAAGATGTTAATAACTAAGTAAGTTTTAGGAGTCTCATTGTGATCATGGTATCACGGTATTAGTAGATGCTGGTGTTATTTTGTTTGATTTTGGGAAATGTATTAATATATGTGTCAAACAAGGAACTGAAAACTATTACACTTTGTATTTTTGCTTTTGTCATCATAATCATGTTGAATTTATGTAATCATTGATTTTATTTCATGTGGAATAGCTAATTGCTTCTTAAA
>NM_001256007.3
AGTGTTTGTGTTGGAAGCTCAGCTGATGCAGGCCGGTTGGAGTGGACGTCATTGCCGGGAACGAGCGAGTCGCCGCTGCAGCCCTAGTGACTGCGGCCTGCATCCCGATTGTCTTCTCCTCCAAGGTCTACATGATTACCTGAAGTTTAATAAGTAAGACCATGAATTATGGCATTTCTTAAATGAAGCGTTCAAGAAGTGAGAGAATGTCATAGAAAATAAATGATTTTTAAGTTATGTCTATTAATCTGACTGTAGATATATATATTTACCTCCTTAGTAATGCAAGAAGTGTTTGTGGGAAGCAGAGAAGCAAGCAACTGTATTTCTTGTTCTCACCTAAGCATTACTGGAGGATAAGCCACATCAGTCTACAAAGAGGTTTTCATACAAACATAATAAGATGTAAATGGACCAAAAGTGAAGCACATTCTTGCAGTAAGCACTGTTACTCTCCAAGCAACCATGGTTTACATATTGGGATTTTGAAACTTAGCACTTCTGCTCCCAAGGGACTTACAAAAGTGAACATTTGTATGTCCCGTATTAAAAGTACTTTGAACTCTGTTTCAAAGGCTGTTTTTGGCAATCAAAATGAAATGATTTCACGTTTAGCTCAATTTAAGCCAAGTTCCCAAATTTTAAGAAAAGTATCGGATAGTGGCTGGTTAAAACAGAAAAACATCAAACAAGCCATCAAATCTCTGAAAAAATATAGTGACAAATCAGCAGAAAAGAGTCCTTTTCCAGAAGAGAAAAGTCACATTATAGACAAAGAAGAAGATATAGGTAAACGCAGTCTTTTTCATTACACAAGTTCTATAACCACAAAATTTGGAGACTCATTCTACTTTTTATCAAATCATATTAATTCATATTTCAAACGTAAGGAAAAAATGTCTCAACAAAAGGAAAATGAACATTTCCGGGACAAATCAGAACTTGAAGATAAAAAGGTAGAAGAGGGGAAATTAAGATCTCCAGATCCTGGCATCCTGGCTTATAAGCCAGGCTCAGAATCTGTACATACGGTGGACAAGCCTACAAGTCCTTCTGCGATACCTGATGTTCTTCAAGTTTCAACTAAACAAAGTATTGCTAACTTTCTTTCTCGTCCCACGGAAGGTGTACAAGCTTTAGTAGGTGGTTATATTGGTGGACTTGTCCCCAAATTAAAGTATGATTCAAAGAGTCAGTCAGAAGAACAGGAAGAGCCTGCTAAAACTGATCAGGCTGTCAGCAAAGACAGAAATGCAGAGGAGAAAAAGCGTTTATCTCTTCAGCGAGAAAAGATTATCGCAAGGGTGAGTATTGATAACAGGACCCGGGCATTAGTTCAGGCATTAAGAAGAACAACTGACCCAAAGCTCTGCATTACTAGGGTTGAAGAACTGACTTTTCATCTTCTAGAATTTCCTGAAGGAAAAGGAGTGGCTGTCAAGGAAAGAATTATTCCATATTTATTACGACTGAGACAAATTAAGGATGAAACTCTTCAGGCTGCAGTTAGAGAAATTTTGGCCCTAATTGGCTATGTGGATCCAGTGAAAGGGAGAGGAATCCGAATTCTCTCAATTGATGGTGGAGGAACAAGGGGCGTGGTTGCTCTCCAGACCCTACGAAAATTAGTTGAACTTACTCAGAAGCCAGTTCATCAGCTCTTTGATTACATTTGTGGTGTAAGCACAGGTGCCATATTAGCTTTCATGTTGGGGTTGTTTCATATGCCCTTGGATGAATGTGAGGAACTTTATCGAAAATTAGGATCAGATGTATTTTCACAAAATGTCATTGTTGGAACAGTAAAAATGAGTTGGAGCCATGCATTTTATGACAGTCAAACATGGGAAAACATTCTTAAGGATAGGATGGGATCTGCACTGATGATTGAAACAGCAAGAAACCCCACATGTCCTAAGGTAGCTGCTGTAAGTACCATAGTAAATAGAGGGATAACACCCAAAGCTTTTGTGTTCAGAAACTATGGTCATTTTCCTGGAATCAACTCTCATTATTTGGGAGGCTGTCAGTATAAAATGTGGCAGGCCATTAGAGCCTCATCTGCTGCTCCAGGCTACTTTGCAGAATATGCATTGGGAAATGATCTTCATCAAGATGGAGGTTTGCTTCTGAATAACCCTTCGGCATTAGCTATGCATGAGTGTAAATGTCTTTGGCCAGATGTGCCGTTAGAGTGCATAGTATCCCTGGGCACTGGACGTTATGAGAGTGATGTGAGAAACACGGTAACATACACAAGCTTGAAAACTAAACTTTCTAATGTTATCAACAGTGCTACAGATACAGAAGAAGTCCATATAATGCTTGATGGCCTGTTACCTCCTGACACCTATTTTAGATTCAATCCTGTAATGTGTGAAAACATACCTCTAGATGAAAGTCGAAATGAAAAGCTGGATCAGCTGCAGTTGGAAGGGTTGAAATACATAGAAAGAAATGAACAAAAAATGAAAAAAGTTGCAAAAATATTAAGTCAAGAAAAAACAACTCTGCAGAAAATTAATGATTGGATAAAATTAAAAACTGATATGTATGAAGGACTTCCATTCTTTTCAAAATTGTGATGAGTATATGCTTATGTTCTCATAAATGAAGGTCTGTTTAGAAGATCAACCACATTCAATAAGGAATTGTGGGGTTCGACATGAGTTAACTTTGAAATACGTATGAATTCTGGAGAATCCTGAAAAAGACGGTGCTTCAACCAGCTTGCATAGCACAGAGAATATTCTTGGTTACAGAATTCATATGGGAACTAGGCTTTTAAGATGTTAATAATTAGCTAAGCTTTAGTAACCCTTACTGTGCTAGTAGATTTTAGTAGATATTGGTGTTATATTGTTTGATGTTTGAAAATATATTAATATATGTGCCGAACAAGAAACCGAAAGCTATATTGTACTGTGTATTTTTACTTTAGTCCTCATAATCATGTTGAATTTATGTGATCATTGATTTTATTTCATATGGAAAAGCTAATTTCTTCTTAAATTTACATTACCTAATATTCTCACTAGCTATGTTCTCCAATCCACACTGCCTTTTATTGTAATATCATCTAAATAGATGCAGAAAAATGGAATTTTCTCTATTAAAGTATTTTACATTTGACATAAAAAAGAACCAGATACAGTTTTCTATTCAGATATGTTTATTTTAACATTGTTTGGTTAAAAAAGGTGAAGTTCCAGTCAACCACTTTTTACCCCTGAAATTTCAAGATAATGCTATATTAACTTTTCCAGATCTAACACTAGCTTATTCTTCCCTGTTATAAAATGGTTTGAACTTACTGAGGAGATATTCCTATCATTAACAAAAATAAACTATTTAAATAATCTGTTGTTAAAAGGCTAATGTCATTTTAAAATTAATTTTTGTTCATAATGTAGCTCCCCTTTAGCCTTTGAATACACCTGGCAGCAGTATGCTTAAAAATAAGAAGTTAGTTgcctggcgcagtagctcacacctgtaatcccagcactttgggaggccgaggcaggcagatcacctgacgtcaggagtccaagaccagcctggccaacacggtgaaacctcgtctctaataaaaatacaaacattagcccggcatggtggtgcacacctatagtcccagctactcgggaggctaaggcaggagaatggcttgaacctgagagacggaggttgcagtgagccaaatagcgccagtgcactccagcctaggcgacacagcgagactccatctcaaaaaaaaaaaaaaaaaaaagaagaaGTTAGGCTTGTTTTACCTTATTAACTCCTTTGAACTGTCTGGATTTCATGGAAGTTGGTAAGATGCACTTACATGGAACATTGTTCATGCCAAACAAACTCATCTTTATTGTATCTATTTGTCACATAAATCCTTACATGGAATGTTTTGATTTCTTAAGAAAAATGAAACAAAGGTTAGCGCCCCTTGTTTTAGACATACAAACTAAAGCTAGACCCTGTTGCCCAGATAGTCATATTGCTTCTTTGCAATATCAATTcacagaggctgtgagatgtggttcaaagagtggagtcgagagtctggatgctaatcctgcctttgctgcaagaacccttctgtttgttaccttgaggaaggcaaatgtctgtaggctttgcatatctcatttgtaaaatgaggaAAGGTAGCTGTAAAATTTTCTAACATCCGAATTATATAAACTTTAGACATAGTATAAAATAGGAAACTACCAATGATTTCTAAAGATAATATAGTTCTTTCAGACCACAAATAATACATAATAACATGCAACTAAGAACAACTTGTAAATGCAAGAAAAAAACAAATAATTGGAAATCAGAATATTTCTGGGAATTCTTCGTAATAAAGCAAATTTCAAGCACAATAAAGTAATATTTATGCATATTTACATATTTGCACCTCATCATAAGGTCACTCTAGTCCTAAACTGATGTAGTTCATCTGTTTTACAGCTGAAGTTAAGTATGTCCCTTATTTGTGCTTGGCTTATTTCTTTCTTAAATAATACATTACACAAGTGAACTCTG

Publications

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