Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ZNF674P1
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:128098010-128098634  UCSC
Coordinates (T2T) chrX:126411505-126412129  UCSC
Coordinates (hg19) chrX:127231989-127232613  UCSC
Strand -
Parental Sequence XM_011543943.3
Parental seq. overlap 521 bp
Parental seq. overlap (%) 21.3%
Genomic Region Intergenic
Retrocopy Summary ZNF674P1, located on chrX:128098010-128098634, is a retrocopy of the parental gene ZNF674. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ZNF674
Full Name zinc finger protein 674
Also known as MRX92|ZNF673B
Coordinate chrX:46497725-46545466
Strand -
Gene summary This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked cognitive disabilities. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2017]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ZNF674P1
Bonobo Pan paniscus ZNF674P1
Gorilla Gorilla gorilla KRBOX4P1
Orangutan Pongo abelii KRBOX4P1
Gibbon Nomascus leucogenys KRBOX4P1
Green monkey Chlorocebus sabaeus KRBOX4P1
Crab-eating macaque Macaca fascicularis LOC101865568P1
Rhesus Macaca mulatta ZNF674P1
Baboon Papio anubis KRBOX4P1
Golden snub-nosed monkey Rhinopithecus roxellana KRBOX4P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ZNF674P1
TTCAGACCCCAGCTTATCTTTGCCTGTGCTTCCTCACTTAGTCTAAGAAAACCCAGGCTGAGGTCTCAGGAGGAGATCACCATCCTTTTCCAGAGAAGAACAGGATGGCCATGTCCTGGGAATCATTGACCTTCAAAGACATGTTTGTGGACTTTGTCCTGGAGCAATGGCAGCAAATGGACTCTCCTCATAAGAATCTTTACAGGAATGCCATGCTTGGCAACTACAGCCACCTGGTGTCCATGGGGTATCTGGTTGCCAAACCAGATGTTATCTTCAGGTTGGGACGAGGCGAAAAGTCCTGGATGGTAGATGGAGGAAACCCAATGAAGATCTGTCCCGAAATCTAGCAAGTTGATGAACAGATAGATTACTAAAAAGAAAGCCCAGATAAACCTCTGTGGTAAGCTGCACTCATAGACAAGAAAACACTGAAGGATGAAAATGGTCAAGAATGCAGAAGATGTAGAAAAATCATTTATCTGAGAACAGACTTTTTTCGGTAAGACAAAGACTCTCTAAATATTATTCATGGGGAAGATGTTCAAAACAAAATCTAAACCTTCATAGTCAAAATAGAGGCTATGTAAGAAAGAAAGATGAGATATGTAAGGTGTATTGGAAT
>XM_011543943.3
GGGAAGCGGAAATGCTCGGCTGACCCGGAGGGTGGCGCTTCGTTCACACTGGCTGTTGTCATCCGCCCCTGAGGTTTCAGGCTGTCGGCAGTGAAGGTCAGAGTGCAGACCTGAGACCACTGCTCACCGATTTCAGACTCCAGTTTATCTGTGCCTCGGCTTCCCCACTTAGTCGCAGAAGACTTAGGCTGAGGCCCCAGGAAGAGATCTCCATCCTTTGCAGGAGCACAACAAGATGGCCATGTCCCAGGAATCATTGACCTTCAAGGACGTGTTTGTGGACTTCACCCTGGAGGAGTGGCAGCAACTGGACTCTGCCCAGAAGAACCTCTACAGGGATGTCATGCTTGAGAACTACAGCCACCTGGTGTCCGTGGGGCATCTAGTTGGGAAGCCAGATGTGATCTTCAGGTTGGGACCAGGTGACGAGTCCTGGATGGCAGATGGAGGGACCCCGGTACGGACCTGTGCAGGTGAGGACAGGCCAGTCTGGGAAGTTGACGAGCAGATAGATCACTACAAGGAAAGCCAAGACAAATTTCTGTGGCAAGCTGCATTCATAGGCAAGGAAACACTGAAGGATGAAAGTGGTCAAGAATGTAAAATATGTAGAAAAATCATTTATCTCAACACAGACTTTGTTTCTGTAAAACAAAGACTCCCTAAATATTATTCATGGGAAAGGTGTTCAAAACATCATTTAAACTTTCTTGGTCAAAATAGAAGCTATGTAAGAAAGAAAGATGATGGATGTAAGGCATATTGGAAAGTATGCCTCCATTATAATCTTCATAAAGCTCAACCTGCAGAGAGATTTTTTGACCCTAATCAACGAGGGAAAGCCCTCCACCAAAAGCAAGCCCTTAGAAAAAGTCAGAGAAGTCAAACTGGGGAGAAACTCTACAAATGTACTGAATGTGGAAAAGTGTTTATCCAGAAAGCAAACTTAGTTGTACATCAAAGAACTCACACCGGAGAGAAACCTTATGAATGCTGCGAATGTGCAAAAGCCTTCAGCCAGAAGTCAACCCTCATAGCACACCAGAGAACTCACACAGGGGAGAAGCCCTATGAATGCAGTGAATGTGGAAAAACCTTTATCCAGAAGTCAACTCTGATTAAACATCAACGAACTCATACAGGAGAGAAACCATTTGTATGTGACAAATGTCCAAAAGCCTTTAAGAGTTCATATCATCTTATTAGACATGAAAAAACACACATTAGACAAGCATTTTATAAAGGTATTAAATGTACTACGTCCAGCCTTATATATCAAAGAATTCACACAAGTGAGAAACCTCAGTGCAGTGAACATGGGAAAGCCTCTGATGAGAAGCCCAGTCCCACTAAACATTGGAGAACTCATACAAAAGAGAACATTTATGAGTGTAGTAAATGTGGGAAAAGCTTCAGAGGAAAGTCACACCTCTCTGTTCATCAGAGAATTCATACAGGAGAGAAACCCTATGAATGTAGTATATGTGGGAAGACTTTCAGTGGAAAGTCACACCTCTCTGTCCATCATAGAACTCATACAGGAGAGAAACCTTATGAATGCAGAAGATGTGGGAAAGCCTTTGGGGAGAAGTCAACCCTTATTGTACATCAGAGAATGCATACAGGAGAGAAACCCTATAAATGCAACGAATGTGGGAAAGCCTTTAGTGAGAAGTCACCACTGATTAAACATCAGAGAATTCATACAGGAGAGAGACCCTATGAATGCACTGACTGTAAAAAAGCCTTCAGTAGGAAGTCAACTCTCATCAAACATCAGAGAATTCATACAGGAGAAAAACCTTACAAATGTAGTGAATGTGGGAAGGCCTTCAGTGTGAAATCAACTCTCATTGTGCATCACAGAACTCATACAGGAGAGAAACCTTATGAATGCAGAGACTGTGGGAAAGCATTCAGTGGGAAGTCAACTCTCATTAAACATCAGAGAAGTCACACAGGAGATAAAAACCTATGATTATACTTGAGAGTGGGATAATTATACTAGTAGTTATTTGTCATTTGACTATTACTAGTCTCATTATTTGTCAAATAATCATGGCGAGTAATCTTATAAATGTCCAGAATATTGGAAATTCTTCATATGTTAATGTTCATTTAACTTAATACAAAGTACAAAAGTATAATTCCAGAGGTGTCAATAAATGTGATCAGTTTTTTCACCCAGAATTCTTCACCCAGGAGTGAAGAACTGTATGTCAAATAATTCAAAAGGGGCAAAACTGAATGTAGTTATGTGGGAAAGCCTTCAGAAATAATTTAAATGGCACTGTTTATCAGAGTATGTATGCCGAGGAAAACTAAGAATTTAGTGAGCTTATAAAACCATGGTAgccaggcgtggtacgtagctcacacctgtaatcctagcacttttgggaggctgaggtgggcagattgcttgagctcacaagtttgagacca

Publications

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