Summary

Retrocopy Name	POLE3P1
Species	Homo sapiens
Coordinates (hg38)	chrX:129852029-129853305  UCSC
Coordinates (T2T)	chrX:128170809-128172085  UCSC
Coordinates (hg19)	chrX:128986005-128987281  UCSC
Strand	+
Parental Sequence	NM_001278255.1
Parental seq. overlap	988 bp
Parental seq. overlap (%)	44%
Genomic Region	Intergenic
Retrocopy Summary	POLE3P1, located on chrX:129852029-129853305, is a retrocopy of the parental gene POLE3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name	POLE3
Full Name	DNA polymerase epsilon 3, accessory subunit
Also known as	CHARAC17|CHRAC17|CHRAC2|YBL1|p17
Coordinate	chr9:113407235-113410749
Strand	-
Gene summary	POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004]

Homology

	Species	Scientific Name	Retrocopy
	Chimpanzee	Pan troglodytes	POLE3P1
	Bonobo	Pan paniscus	POLE3P1
	Gorilla	Gorilla gorilla	POLE3P1
	Orangutan	Pongo abelii	POLE3P1
	Gibbon	Nomascus leucogenys	Without Homology
	Green monkey	Chlorocebus sabaeus	Without Homology
	Crab-eating macaque	Macaca fascicularis	Without Homology
	Rhesus	Macaca mulatta	Without Homology
	Baboon	Papio anubis	Without Homology
	Golden snub-nosed monkey	Rhinopithecus roxellana	Without Homology
	Marmoset	Callithrix jacchus	Without Homology
	Mouse lemur	Microcebus murinus	Without Homology
	Mouse	Mus musculus	Without Homology
	Rat	Rattus norvegicus	Without Homology
	Chinese hamster	Cricetulus griseus	Without Homology
	Rabbit	Oryctolagus cuniculus	Without Homology
	Pig	Sus scrofa	Without Homology
	Cow	Bos taurus	Without Homology
	Sheep	Ovis aries	Without Homology
	Dolphin	Tursiops truncatus	Without Homology
	Horse	Equus caballus	Without Homology
	Dog	Canis familiaris	Without Homology
	Panda	Ailuropoda melanoleuca	Without Homology
	Cat	Felis catus	Without Homology
	Pale spear-nosed bat	Phyllostomus discolor	Without Homology
	Velvety free-tailed bat	Molossus molossus	Without Homology
	Greater mouse-eared bat	Myotis myotis	Without Homology
	Kuhl's pipistrelle	Pipistrellus kuhlii	Without Homology
	Greater horseshoe bat	Rhinolophus ferrumequinum	Without Homology
	Egyptian rousette	Rousettus aegyptiacus	Without Homology
	Sloth	Choloepus didactylus	Without Homology
	Tasmanian Devil	Sarcophilus harrisii	Without Homology
	Opossum	Monodelphis domestica	Without Homology
	Platypus	Ornithorhynchus anatinus	Without Homology
	Chicken	Gallus gallus	Without Homology
	Turkey	Meleagris gallopavo	Without Homology
	Zebra Finch	Taeniopygia guttata	Without Homology
	Budgerigar	Melopsittacus undulatus	Without Homology
	Painted Turtle	Chrysemys picta	Without Homology
	Lizard	Anolis Carolinensis	Without Homology
	Frog	Xenopus tropicalis	Without Homology
	Zebrafish	Danio rerio	Without Homology
	Drosophila	Drosophila melanogaster	Without Homology

Expression

This retrocopy transcript is not present in the GTEx database for expression quantification.

This retrocopy transcript is not present in the ARCHS4 database for expression quantification

Related Sequence

>POLE3P1

GAAGCTCTGGATGCATATAGGCAGGAGCAGAAAGGCAAGAAGGGGGCCTCCAACTGAATAGGGCAGGAGACTGTGGCATCTTGGAAGGTACCACTTGAGATGAGATGTGCTACATGTTTCTGTGAAGCTTTTTCATGCTGGGCAGAGTAGTCTCAGGCAGAAGTGCCTGAAAAGATCAGAATAAAAACTGACTAGAAATACCATCAAAACCAGCACTTCCTAAACTCAAAGCATCTGAGTAGCAGAATCCTGTTTTACTTCATCAACCTCAAGGTTATGACTTTTTGGCAAAAGGGATTCTGAACGGCTAAATTAGTCAGTTTGATCACTTTTGGTTACTTATTTGTATGGTTAGGTGGTTTTTGATCCGCAGTCTTTCCTATTCCCCCAAATAAGTAATAATAACTTCCATGCTGCCTGATGTGTTCCAGATCACAGAGGCAGCCAAAGCTCAGGAAAATTGGGGCTTTGCTTATGGTCAGCCTATGTTTGATTGCACAGTCTTTGACAATAGTAGCTTACTAAGACTGGTCAGAATGAGTAAGCTTTAGGAAACTACTAAAATGCTGTGGGATAATAACAAAATCTGTTCTGTCTCTTCACTTGACAGAAGCGTTAACTGAATTTTGTTTTTCATAGACCCACTTGGCTCAAAACCTTTCTAAATTGCCTGTAGATAATTCGACCTGCTGGGGTGGGGGTAATCTGGTCACAAATGTTCTTAAATCAGCAGTTTAAAATGGTATTCGTCAAGCAAGGGTGCCAGTGTCTTACTTTTACAAAAACAGATGGCATAGTGTCACATGTATCTTACTCTCTGCTACTGTACAGCTTTGGGATTTGTCATCACCTGCTGGAAGGTGTAAAACCCCAGGCTTCCTCTTCTTGAAGTCCATCTCCCAGACTTGTGACTATGGCTTTTCATTCTTCAATTCATGATGAGTTCCAAACTTTATTTCCTCTAGGCACAGtTTTCTCACTTATGTCAGTCTAGGAGCTTTGATTACCTGCTTAGTACTCCAAAGTGTGAGTTCCTCTGATCTCTTGATTCCTTGGTTCTAATCTCA

>NM_001278255.1

CCTAAAGGGATCCGCCCCGCCGAGTCAGCCACGCCTTCGTCTCCCACGCGCTGCGCCCGGCCGCGCCGTCACCCAGCAGCGGCGCAGGGCACCATGGGAAACGGACGGAAGCTCCATTGAGCCAAATAAGTTGGGTCAGACCGTAGCGACGCGGGAAGTCCGGACGCAGTAGCTCCCTGAAGCGGAGGCGAAGGGGAGTTTAAGCCCCAGCGGCGGCAATGGCGGAGAGGCCCGAGGACCTAAACCTGCCCAATGCCGTGATCACCAGGATCATCAAGGAGGCGCTCCCGGACGGTGTCAACATCTCCAAGGAGGCCCGGAGCGCCATCTCCCGCGCCGCCAGCGTCTTCGTGCTGTACGCCACATCCTGTGCTAACAACTTTGCAATGAAAGGAAAGCGGAAGACGCTGAATGCCAGTGATGTGCTCTCAGCCATGGAAGAGATGGAGTTCCAGCGGTTCGTTACCCCATTGAAAGAAGCTCTGGAAGCATATAGGCGGGAGCAGAAAGGCAAGAAGGAGGCCTCAGAGCAAAAGAAGAAGGACAAAGACAAAAAAACAGACTCGGAAGAGCAAGACAAGAGCAGGGATGAGGACAATGATGAAGACGAAGAAAGGCTGGAAGAAGAAGAACAGAATGAAGAGGAAGAAGTAGACAACTGAAAAGGGCGGGAGACTGTGGCACCTTGGAAGGTACCACTTGAAATGAGACGTGCTACGTGTTTCTGTGAAGCTTTTCCATGCTGGGCAGAGTAGTCTCAGGCAAAAGTGCCTGAAAAGATCAGAATAAAAACTGACTAGAAATACCGTCAAAACCAGCACTTACCAAACTCAGAGCATCTGAGTAGCAGAATCCTGTTTTGCTTCATCAATCTGAAGGTTATGGCCTTTTGACAAGAGGGATTCTGAACGACTAAATTAGTCAGTTTGCTCGCTTTTGTTTACTTAAATGTATGGTTAGATGGTTTTTGATCTGCAGTCTTCCCTAGTCCCCCAAATAAGTAATAATAACTTCCATGCTGCCTGCTGTGTTCCAGATCACAGAGGCAGCCAAGGCTCAGGAAAAACTGGGGCTTTGCTTATGGTCAGCCTATGTTTGATTGCACAGTCTTTGACAATAGTAGCTTACTAAGACTGCTCAGAATGAGTAAGCTTTAGGAAACTACTAAAATGCTGTGGGAGAATAACAAAATCCGTTCTCTCTCTTCACTTGACAGAAGCATTAACTGAATTTTGTTTTTCATAGACCCACTTGGCCCAAAACCTTTCTATATTGCCTGTAGATGATCGGCCTGCTGGTGTGGTAGTAATCTGATCACAGATATTCTTAAATCAGCAGTGTGGAATGGTATTAGTCAAACATGGTGCCAGTGTCTTTTACAAAAACAGATGGCATAGTGTCAGATGTACCTTACTCTCTGCTACTGTACAGCTTTAGGATTTGTCATCACCTCCCGGAAGGTGTAAAACCCCAGGCTTCCTCTTCTTGTAGTCCATCTCCCAGACTTGTGACTATGGCTTTTCATTCTTCAATTCATGACGAGTGCCAAACTTGATTTTCTCTAGGCACAGCTTTCTCCCTCTGTGCCTCCTGCTTCCTTTCTCTCTCCTGCCTCTCCTCTGCTCCCCATCCCACTTTCTCATCTGCCTCCTTTTCTCACTTCTGTCAGTCTGTAAGCTTTGATAACCTGCTTAATACTCCAAAGTGTGAGTTCCTCTGATCTCTTGATTCCTTAGTTCTAATCTCACGttttgtttttaagagatggagtctctcactctgtggcccaggctggagtgcagtggcatgatcatagctcattgcatccttgaaatcctgggctcaggtgatcctcccgcctgagcctcctgagtatctgggactacagatgcgtgccaccaagcctggcTAATTTTGTCTCATGTCTTCTAAAAATTATTTTGTGAAGCCCCTTCACAAAAAACCTTAAGGGAAATCTGATGGTGCTCAGGAATCTAACTCTCCCTAAACCATCCTCTTTAACTGCTTCTAAAATATCTCTGTTGGCCTTTCTTAGCCTTTTTCTGTTTCCATTCAGTGCTCCAAGCGCTTTTTGTTTCTAAGTTGAGTGCTTGGGGTTTGACAGGTAGTGACGTGTAGTTTGACACTGTTAACTTGTTAAATACAGTGAAAAGTTTGTGAGTGAAGAATGCTGAGAAGATTGTAATGCTTTGTACAAATAAAAGTCTTGTTAAAAAA

Publications

PMID - Link	Title
No publications available for this retrocopy