Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RAB28P5
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr4). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:136847357-136848167  UCSC
Coordinates (T2T) chrX:135156078-135156888  UCSC
Coordinates (hg19) chrX:135929516-135930326  UCSC
Strand +
Parental Sequence NM_001017979.3
Parental seq. overlap 731 bp
Parental seq. overlap (%) 43.2%
Genomic Region Intergenic
Retrocopy Summary RAB28P5, located on chrX:136847357-136848167, is a retrocopy of the parental gene RAB28. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RAB28
Full Name RAB28, member RAS oncogene family
Also known as CORD18
Coordinate chr4:13367724-13484340
Strand -
Gene summary This gene encodes a member of the Rab subfamily of Ras-related small GTPases. The encoded protein may be involved in regulating intracellular trafficking. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 9 and X. [provided by RefSeq, Apr 2009]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RAB28P2
Bonobo Pan paniscus RAB28P1
Gorilla Gorilla gorilla RAB28P1
Orangutan Pongo abelii RAB28P2
Gibbon Nomascus leucogenys RAB28P2
Crab-eating macaque Macaca fascicularis RAB28P2
Rhesus Macaca mulatta RAB28P2
Baboon Papio anubis RAB28P2
Golden snub-nosed monkey Rhinopithecus roxellana RAB28P1
Marmoset Callithrix jacchus RAB28P2
Green monkey Chlorocebus sabaeus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RAB28P5
CGGGGCAGGCATGGTTCCTGGGACATCATGTAGGACTCTAAGGAAGAGAGCCAGGACCAGCACTGAAAATCATCGTGCTAGGGAACAGCACCTCCCGGAAGACCTCCTTAGCTACAGATTTTGCTCAAAAAACTTTCAGGAACCAGTACAAACTATAGGACTGGATTTCTTTTGAGAAGGATAACATTGCCAGGAAACTTGAATGTTACTCTCTAGTTTGGGATACAGGAGGCCGGACAATAAGAAGCAAAATGTTGGACAGATCCATCTATGGAGCACAGGAAATCATCTTGGTATATGGTATTACAAGTTATCAAAGCTTTGAGAATTTTTAGAAGATTAGTGAAGAAAGTGAGTGAAGAGTCAGAAACTCAGCCGCTGGTTACCTTAGTGGGCAATAAAATTGATTTGGAGCATAATCAAACAGTAAAACCTGAAAAACACTTACGGTTTTGCCAGGAAAATGGTTTTAATAGCCACTTTGTTTCAGCCAAGGCAAGAGACTCTGTCTTCCTGTGTTTTCAAAAAGTTGTTGCTGAAATCCTTGGAATCAAATTAAACAAAGCAGAAATAGAACAGTCACAGAGGGTGGTAAAGGCAGATATTGTAAACTACAACCAGGAACCTATGGCAAGAGCTGTTAACCCTTCTAGAAGCTCTGTGTGTGCAGTTGGGTGAGCTCATTTTTCCATTGTGTTGATAGTTTTGGCTGCCCTTCACCTCTGGGTGTGTCTGAGAACTTCTAAGAACTTGTTTTATCAGTGACCATCTCTGTAGTTCAGTTAACACTTTCCTCCGAACTTGCTTCATC
>NM_001017979.3
GCAGAGGGCGGGGAGGTGGGCAAGATGGCGCTTGCCGAGTGATTCTCCTCGAATACCTCCTGCCGGCGCGGAGACACCGGGGCGGGGGTCCTGCCGCAACTACCTCCCTTCCTCCTCTCCCCCGCCCCCGGAGCCTTCATCCTTCCCTTCCCCCCCCACCTCGAGGGGCGGGCCTGGTTCCCGGGACACCATGTCGGACTCTGAGGAGGAGAGCCAGGACCGGCAACTGAAAATCGTCGTGCTGGGGGACGGCGCCTCCGGGAAGACCTCCTTAACTACGTGTTTTGCTCAAGAAACTTTTGGGAAACAGTACAAACAAACTATAGGACTGGATTTCTTTTTGAGAAGGATAACATTGCCAGGAAACTTGAATGTTACCCTTCAAATTTGGGATATAGGAGGGCAGACAATAGGAGGCAAAATGTTGGATAAATATATCTATGGAGCACAGGGAGTCCTCTTGGTATATGATATTACAAATTATCAAAGCTTTGAGAATTTAGAAGATTGGTATACTGTGGTGAAGAAAGTGAGCGAGGAGTCAGAAACTCAGCCACTGGTTGCCTTGGTAGGCAATAAAATTGATTTGGAGCATATGCGAACAATAAAACCTGAAAAACACTTACGGTTTTGCCAGGAAAATGGTTTTAGTAGCCACTTTGTCTCAGCCAAGACAGGAGACTCTGTCTTCCTGTGCTTTCAGAAAGTTGCTGCTGAAATCCTTGGGATCAAATTAAACAAAGCAGAAATAGAACAGTCACAGAGGGTGGTGAAGGCAGATATTGTAAACTACAACCAGGAACCTATGTCAAGGACTGTTAACCCTCCTAGAAGCTCTATGTGTGCAGTTCAGTGAGCGCATTTTTCTTTTGTGTTGATAGTTCTGGCTGCCCTTCACCTCTGGGTGGGCCCGAGGACTTCTAGGAACTTGTTTTATCAGTGACCATCTCTGTAGTTCAGTTAACACTTTACTCCCAACTTGCTTCATCATTGCTATTGCCTCACAGTGGCAGGCAGCTCCTTGGATTTGAAAGAATTCAACTTTGGGACCACACACTTTGAATTCAAAATGGAAAACCCATTCCCTGGAATTAGACTGCTTCATTGCAAAAGAATGATGTTGTTTCTTTGTATGTCCTTGCTTCTTTTTTCATTGATGTAAATTTTTTTAACTTAATATGAAAACTCTCCAAGTCTTGATCATCAGCCAGGATTTTGCCACAGCAATTTCATTCTCTTATCGGAACTTGTATGTGTCAAAGTATACTTCAGAGTGCAAACATTAAGCAAGTAATATATTTTACCTACAGATACTTATGAAGACATTCTTTCGCTATCGTGAGTAAAAGTATATAAAGCTGTTTCTAACTGAAAATGCTTGAAATAAGCCTGTAATAGAAATATTTTTTCATTTTTTAAAAAAGGGCCTAAATTGTTTATATTGTAGTTTGTAACTCACAAAGTAATATTTGATATTGTATTTTTATTACTGTATCGTTGTCGTTATGTATTGTGTAATACTCAGGTTTGAAGGCTTTCTGAATTCTGATAAATGTTCAGCTGATGCTCCACGTGGAATTTCTCTTGCAAACTGCATAAGAGTACTCCCGAGAATGAGTTATGACATTGTGGATCAGACTGTACCTGATGTTCAGATGTTTTTCTTTCACAAATAAACTTATTTAAATTA

Publications

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