Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name TWF1P2
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr12). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:155288173-155291419  UCSC
Coordinates (T2T) chrX:153525489-153528735  UCSC
Coordinates (hg19) chrX:154517464-154520710  UCSC
Strand -
Parental Sequence NM_002822.5
Parental seq. overlap 2035 bp
Parental seq. overlap (%) 57.7%
Genomic Region Intragenic (CLIC2)
Retrocopy Summary TWF1P2, located on chrX:155288173-155291419, is a retrocopy of the parental gene TWF1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TWF1
Full Name twinfilin actin binding protein 1
Also known as A6|PTK9
Coordinate chr12:43793723-43806317
Strand -
Gene summary This gene encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TWF1P1
Bonobo Pan paniscus TWF1P1
Orangutan Pongo abelii TWF1P1
Gibbon Nomascus leucogenys TWF1P1
Rat Rattus norvegicus Twf1P1
Gorilla Gorilla gorilla Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TWF1P2
AAAGCACTTATTTCTAAACCTTATTATCTAAGGTAATATATGTACCTTTCAGAAATTTGTGTTCAAGTAAGTAAAGCATATTAGAATAATTATGGGTTGACAGATTTTTTATATAGAATTTAGAGTATTTGTGTGGGGTTTTGTTTGTTTACAAATAATCAGACTATAGTATTTAAACATGCAAAATAATTGACAATAATGTTGCACTTGTTTATTAAAGATATAAGTTGTTCCATGGGAGCACACATGGACAGACATACATACACCCAAACTATTGCATTAAGAATCCTGGAGCTGTGTTGCAGACCATAGCTGAAGCAGTTATTTTCAGTCAGGAAGACTACCTGTCATGAAGGTATAAAATAATTTAGAAGTGAATGTTTTTCTGTACCATCTATGTGCAATTATACTCTAAATTCCACTACACTACATTAAAGTAAATGGACATTCCAGAATATAGATGTGATTATAGTCTTAAACTAATTATTATTAAACCTATGATTGCTGAAAATCAGTGATGCATTTGTTATAGAGCATAACTCATCATTTACAGTATGTTTTAGGTGGCATTATCATACCTAGACAATGAATAACATATTCCCAATAAATTTATATAGCAGTGAAGAATTACATGCCTTCTGGTGGACATTTTATAAGTGCATTTTGTATCACAATAAAAAATTTTTCTCATAATTAGGGGCCCAGCGGAAAATGAAGCTACTACTGATTCAAGTCATCACATTAAACATAGCAATACTAGTTTTTTAAAAGTCCAGCTTTCAATACAGGAGAACTGAAATCATTCCATGTTGATATAAAGTAGGGAAAAAATTGTACTTTTTGGAAAATAGCACTTGTCACTTCTATGTACTTTTTAAATTAATGTTACATAAGAGTCATGATTTCTATTTTTGACTTAAAGCTAGAAAAGAGTTCAACATAATGTTTAATTTTGTCACACTGTTTTTATAGTGTTGATTCTACACTTTCACATACTTGTTAAAATTTTATACAATTGAGCCAGTTCTAGAAAGTCTGATGTCTCGAAGGATAAACTTACTACTTTCATGTAGGACAGAAAGACCTTAAAATATTCTTATCACTTAATGAATATGTTAAAGACCAGGCTAGAGTATTTTCTAAGCTGGAAACTTAGTGTGCCTCGGAAAAGGCCAGAAGTTGCTTATTCTGAGTAGCTGTTCTAACTCTGTCAGACTATAGGATCATCTCTGCAACTTTTAGAAATAGTGCTTTATATTGCAGCAGTCTTTTATATTTGACTTTTTTTTAAACAGCATTAAAATTGCAGATCAGCTCACTCTGAAACTTTAAGGGTACCAGATATTTTCTATACTGCAGGATTTCTGATGACATTGAAAGACTTTAAACAGCCTTAGTAAATTATCTAAGGCTCTGTGAAGCCAAACATTTATGTTCAGATTGAAATTTAAATTAATATCATTCAAAAGGAAATAAAAAATGTTGAAAGAGTTTTAAAAATCAGGATTGACTTTTTTCTCCAAAACCATACATTTATAGGCAAATTGTGTTCTTTGTCACTTCTGAACAAATATTCAGATTTAAAATTACTTTAAAGTCCTAGTATTTAACAGGCTAGCACAGATAAACACCTTAATAATCTCCTTTCAATTAATATTGTATTTCAAACCACATTTAACTGTCTTCTAATGCTTTGCATTTTCAGTTACAACCTAGAGAGATTTTGAGCCTCATATTTCTTTGATACTTGAAATAGAGGAAGCTAGAATACTTCATGTTTAGTCTGTTAAACCTGCTACAAAAACCATAACTTTGAGGCATTTTCTAAATGAGCTGTGGGGATCCAGGATTTGTAATTTATTGATCTAAACTTTATGCTGCGTAAATCAGTTATCAGAAATGCACATTTCATAGGGTGAAACACTCATGCACTCAGCATCGGAGCCAGGAGCTAGTGGCCGCCGCCACGTCCCACCAGACCTGCATCCAAGCAAGTGAAGATGTTAAAGAGATCTTGCCAGAGCCAGAAATGGAAAGTACAGACCTCTGAAAATATCTATTGAAAATGGGCAACTTATGATTGGATCATATATAGTCAGCCTTCAGATTCCTGGGATAACGATTATGATTCCTTTGTTTTACCCCTGTTGGAGGACAAACAACTGTGCTATATATTATTCAGGTTAGATTCTCAGAATGCCCAGGGATATGAATGGATATTCATTGCATGGTTTCCAGATCATTCTCATGTCCGTCAAAAAAGGTTATATGCAGCAACAAGAGCAACTCTGGAAAAGGAATCTGGAGGTGGCCACGTTAAAGATGAAGTATTTGGAACAGTAAAGGAAGATGTATCATTACATGGATATAAAAAATGTTTGCTCTCACAATCTTCCCCTGCCCCACTGACTGCAGCTGAGGAAGAATTATGACATTAAAATCAATGAGGTACAGACTGACGTGGGTGTGGACGCTAAGCATCAAACACTACAAGGAGTAGCATTTCCTATTTCTCGAGAAGCTTTTCAGGCTTTGGAAAAAATAAATAACAGCTGAACTATGTGCAGTTGGAAATAAACATAAAAAATGAAATTATAATTTTGGCCAACACAACAAATACAGAACTAAAAGATTTGCCAAAGAGGATTCCCAAGGATTCAGCTCGTTACCATTTCTTTCTGTATAAACATTCCCATGAAGGAGACTATTTAGAGTCCATAGTTTTTATCTATTCAATGCCCAGATACACATGCAGTATAAGAGAACGGATGCTGTATTCTAGCTGCAAGAGCCCTCTGCTAGAAATTGTAGAAAGACAACTATGGATGTTGTAATGGATGTAATTAGAAAGATTGAGATAGACAATGAGGATTAGT
>NM_002822.5
CACTTCCTGGGGCCGCCGGCCGGGGCCGCTGGCTGCACTCAGCGCCGGAGCCGGGAGCTAGCGGCCGCCGCCATGTCCCACCAGACCGGCATCCAAGCAAGTGAAGATGTTAAAGAGATCTTTGCCAGAGCCAGAAATGGAAAGTACAGACTTCTGAAAATATCTATTGAAAATGAGCAACTTGTGATTGGATCATATAGTCAGCCTTCAGATTCCTGGGATAAGGATTATGATTCCTTTGTTTTACCCCTGTTGGAGGACAAACAACCATGCTATATATTATTCAGGTTAGATTCTCAGAATGCCCAGGGATATGAATGGATATTCATTGCATGGTCTCCAGATCATTCTCATGTTCGTCAAAAAATGTTGTATGCAGCAACAAGAGCAACTCTGAAGAAGGAATTTGGAGGTGGCCACATTAAAGATGAAGTATTTGGAACAGTAAAGGAAGATGTATCATTACATGGATATAAAAAATACTTGCTGTCACAATCTTCCCCTGCCCCACTGACTGCAGCTGAGGAAGAACTACGACAGATTAAAATCAATGAGGTACAGACTGACGTGGGTGTGGACACTAAGCATCAAACACTACAAGGAGTAGCATTTCCCATTTCTCGAGAAGCCTTTCAGGCTTTGGAAAAATTGAATAATAGACAGCTCAACTATGTGCAGTTGGAAATAGATATAAAAAATGAAATTATAATTTTGGCCAACACAACAAATACAGAACTGAAAGATTTGCCAAAGAGGATTCCCAAGGATTCAGCTCGTTACCATTTCTTTCTGTATAAACATTCCCATGAAGGAGACTATTTAGAGTCCATAGTTTTTATTTATTCAATGCCTGGATACACATGCAGTATAAGAGAGCGGATGCTGTATTCTAGCTGCAAGAGCCGTCTGCTAGAAATTGTAGAAAGACAACTACAAATGGATGTAATTAGAAAGATCGAGATAGACAATGGGGATGAGTTGACTGCAGACTTCCTTTATGAAGAAGTACATCCCAAGCAGCATGCACACAAGCAAAGTTTTGCAAAACCAAAAGGTCCTGCAGGAAAAAGAGGAATTCGAAGACTAATTAGGGGCCCAGCGGAAACTGAAGCTACTACTGATTAAAGTCATCACATTAAACATTGTAATACTAGTTTTTTAAAAGTCCAGCTTTTAGTACAGGAGAACTGAAATCATTCCATGTTGATATAAAGTAGGGAAAAAAATTGTACTTTTTGGAAAATAGCACTTTTCACTTCTGTGTGTTTTTAAAATTAATGTTATAGAAGACTCATGATTTCTATTTTTGAGTTAAAGCTAGAAAAGGGTTCAACATAATGTTTAATTTTGTCACACTGTTTTCATAGCGTTGATTCCACACTTCAAATACTTCTTAAAATTTTATACAGTTGGGCCAGTTCTAGAAAGTCTGATGTCTCAAAGGGTAAACTTACTACTTTCTTGTGGGACAGAAAGACCTTAAAATATTCATATTACTTAATGAATATGTTAAGGACCAGGCTAGAGTATTTTCTAAGCTGGAAACTTAGTGTGCCTTGGAAAAGGCCGCAAGTTGCTTACTCCGAGTAGCTGTGCTAGCTCTGTCAGACTGTAGGATCATGTCTGCAACTTTTAGAAATAGTGCTTTATATTGCAGCAGTCTTTTATATTTGACTTTTTTTTAATAGCATTAAAATTGCAGATCAGCTCACTCTGAAACTTTAAGGGTACCAGATATTTTCTATACTGCAGGATTTCTGATGACATTGAAAGACTTTAAACAGCCTTAGTAAATTATCTTTCTAATGCTCTGTGAGGCCAAACATTTATGTTCAGATTGAAATTTAAATTAATATCATTCAAAAGGAAACAAAAAATGTTGAGTTTTAAAAATCAGGATTGACTTTTTTCTCCAAAACCATACATTTATGGGCAAATTGTGTTCTTTATCACTTCCGAGCAAATACTCAGATTTAAAATTACTTTAAAGTCCTGGTACTTAACAGGCTAACGTAGATAAACACCTTAATAATCTCAGTTAATACTGTATTTCAAAACACATTTAACTGTTTTCTAATGCTTTGCATTATCAGTTACAACCTAGAGAGATTTTGAGCCTCATATTTCTTTGATACTTGAAATAGAGGGAGCTAGAACACTTAATGTTTAATCTGTTAAACCTGCTGCAAGAGCCATAACTTTGAGGCATTTTCTAAATGAACTGTGGGGATCCAGGATTTGTAATTTCTTGATCTAAACTTTATGCTGCATAAATCACTTATCGGAAATGCACATTTCATAGTGTGAAGCACTCATTTCTAAACCTTATTATCTAAGGTAATATATGCACCTTTCAGAAATTTGTGTTCGAGTAAGTAAAGCATATTAGAATAATTGTGGGTTGACAGATTTTTAAAATAGAATTTAGAGTATTTGGGGTTTTGTTTGTTTACAAATAATCAGACTATAATATTTAAACATGCAAAATAACTGACAATAATGTTGCACTTGTTTACTAAAGATATAAGTTGTTCCATGGGTGTACACGTAGACAGACACACATACACCCAAATTATTGCATTAAGAATCCTGGAGCAGACCATAGCTGAAGCTGTTATTTTCAGTCAGGAAGACTACCTGTCATGAAGGTATAAAATAATTTAGAAGTGAATGTTTTTCTGTACCATCTATGTGCAATTATACTCTAAATTCCACTACACTACATTAAAGTAAATGGACATTCCAGAATATAGATGTGATTATAGTCTTAAACTAATTATTATTAAACCAATGATTGCTGAAAATCAGTGATGCATTTGTTATAGAGTATAACTCATCGTTTACAGTATGTTTTAGTTGGCAGTATCATACCTAGATGGTGAATAACATATTCCCAGTAAATTTATATAGCAGTGAAGAATTACATGCCTTCTGGTGGACATTTTATAAGTGCATTTTATATCACAATAAAAATTTTTTCTCTTTAA

Publications

PMID - Link Title