Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PHF10P1
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr6). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:155291938-155293432  UCSC
Coordinates (T2T) chrX:153529254-153530756  UCSC
Coordinates (hg19) chrX:154521229-154522731  UCSC
Strand +
Parental Sequence NM_018288.4
Parental seq. overlap 1143 bp
Parental seq. overlap (%) 52.5%
Genomic Region Intragenic (CLIC2)
Retrocopy Summary PHF10P1, located on chrX:155291938-155293432, is a retrocopy of the parental gene PHF10. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PHF10
Full Name PHD finger protein 10
Also known as BAF45A|SMARCG4|XAP135
Coordinate chr6:169703902-169724500
Strand -
Gene summary This gene contains a predicted ORF that encodes a protein with two zinc finger domains. The function of the encoded protein is not known. Sequence analysis suggests that multiple alternatively spliced transcript variants are derived from this gene but the full-length nature of only two of them is known. These two splice variants encode different isoforms. A pseudogene for this gene is located on Xq28. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PHF10P1
Bonobo Pan paniscus PHF10P1
Orangutan Pongo abelii PHF10P1
Gibbon Nomascus leucogenys PHF10P1
Gorilla Gorilla gorilla Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PHF10P1
GCCCCGCGGCCATGCGACAGCGACCCAGCCACCCCCGGAGCGCAGTCCTCGAAGGATGAAATTGAAGATAATTCAAATGACCGGACCCAGGCATCCAAAAAGAGGCGAATGGGCTCAGGAGATGGTTCTAGGAGCTGTGAAACTTCAAGTCAAGATCTTGGCTTTAGTTACTATCCAGCATAAAATTTGATAGAGTACAAATGGCCACCTGATGAAACAGGAGAATACTATATGCTTCAAGAACAAGTCAGTTAATATTTGGGTGTGACCTCCTTTAAAAGGAAATATCCAGATTTAGAGAGACGAGATTTGTCTCACAAGGAGAAACTCTACCTGAGAGAGCCAAATGTCATTACTGAAACTCAATGCACTCTAGGTTTAACTGAGCAGTGATGAAGTGATTGTTTTAACGATAAAGGAATATCCAGCCAAACATGCTGAGTATTCTGTTATTCTACAAGAAAAAGAACGTCAACGAATTACAGACCATTACAAAGAGTATTCCCAAATGTAACAACAGAATACTCAGAAAGTTGAAGCCAGTAAAGTGCCTGAGTATATTAAGAAAGCTTAAAAAAGCTGCCAAAAAAAGCAGCAACTTAAACCGGGAACGCATGGAAGAAAGAAGAGCTTATTTTGACTTGCAGACACGTTATCCAGGTGCCTCAAGGGAAGTAGGAAGTTTTGCCAACAGGGCGAACAAAGGTCAGTTCTTACCCAGTGGCTCTCATCCCCGGACAGTTCCAGGAATATTATAAGAGGTACTCACCAGATGAGCTGTGGTATCTGCCATTAAACACAGCCCTGTACGAGGCCACTCTGGATCCTGAGCTCCCTGCTCTAGACAGTGACGGTGATTCAGATGACGGCGAAGATGGTTGAGGTGATGAGAAGCGGAAAAATAAAGGCACTTCGGACAGCTCCTCTGGCAAGGTATCTGAAGGGGAAAGCTCTCCTGACAGCCAGGAGGACTCTTTCCAGGGAAGACAGAAATCAAAAGACAAAGCTGCCACTCCAAGAAAAGATGCTCCCAAACGTTCTGTACTGTCCAACTCAGTTCCTGGGTACAAGCCCAAAGTCATTCCAAATGCTATATGTGGAATTTGTCTGAAGGGTAAGGAGTCCAACAAGAAAGGAAAGGCTGAATCACTTATACACTGCTCCCAGTGTGAGAATAGTGGCCATCCTTCTTGCCTG
>NM_018288.4
GAGTACAACGCCGGGCCGTGGGGAGCCAGGCGGCGGCGGGGCTGAGGCGGCCGCGGGGCTGAGGGGAGCGGCGGGGCTGAGGCGAGCGGCGGGGCTGAGGCGAGCGGCGGGGCTGAGGCGGCCGCGGGGCTGAGGCGAGCGAGCGGCGGGGCTGAGGCGAGCGAGTGGCGGGGCTGAAGGGAGTCGCGGCGGCGCTGAGGCCAGCGGCGGAGCTGTGGGGGGCAACGGTGCTGAGGCGGTGGCCGCGGCCGGGCGGGTTGGGCTGACGTGAGAAGCGCCGCCGCCGCTGGGCCTCCTCCATtccggcccgcagccccgcgccctcccagcctttggcgccctcccgcGCGGGCGGCGCGCTGGCGACGGCCATGGCGGTGGCGGCGGCGCTGGCGGGCCGCGGGGCGCGCGGCGGCAGGGGCCGGCCCCCGGGCGGGCGGGCGGAGGGGGCGGGGCCGGGGCGGCGGGGGGCCCGCgcggcggcggcggcggcggcggcggcagcggcggcggcggccgggacaaggcggaggcgacggcggcggcggcggcgCGGGGCGCTCGGGCTGATGGCGGCGGCGGCCGGGCCCGGGGCTGCGCTGTCCCCGCGGCCGTGCGACAGCGACCCAGCCACCCCCGGAGCGCAGTCCCCGAAGGATGATAATGAAGATAATTCAAATGATGGGACCCAGCCATCCAAAAGGAGGCGAATGGGCTCAGGAGATAGTTCTAGGAGTTGTGAAACTTCAAGTCAAGATCTTGGTTTTAGTTACTATCCAGCAGAAAACTTGATAGAGTACAAATGGCCACCTGATGAAACAGGAGAATACTATATGCTTCAAGAACAAGTCAGTGAATATTTGGGTGTGACCTCCTTTAAAAGGAAATATCCAGATTTAGAGCGACGAGATTTGTCTCACAAGGAGAAACTCTACCTGAGAGAGCTAAATGTCATTACTGAAACTCAGTGCACTCTAGGCTTAACAGCATTGCGCAGTGATGAAGTGATTGATTTAATGATAAAAGAATATCCAGCCAAACATGCTGAGTATTCTGTTATTCTACAAGAAAAAGAACGTCAACGAATTACAGACCATTATAAAGAGTATTCCCAAATGCAACAACAGAATACTCAGAAAGTTGAAGCCAGTAAAGTGCCTGAGTATATTAAGAAAGCTGCCAAAAAAGCAGCAGAATTTAATAGCAACTTAAACCGGGAACGCATGGAAGAAAGAAGAGCTTATTTTGACTTGCAGACACATGTTATCCAGGTACCTCAAGGGAAGTACAAAGTTTTGCCAACAGAGCGAACAAAGGTCAGTTCTTACCCAGTGGCTCTCATCCCCGGACAGTTCCAGGAATATTATAAGAGGTACTCACCAGATGAGCTGCGGTATCTGCCATTAAACACAGCCCTGTATGAGCCCCCTCTGGATCCTGAGCTCCCTGCTCTAGACAGTGATGGTGATTCAGATGATGGCGAAGATGGTCGAGGTGATGAGAAACGGAAAAATAAAGGCACTTCGGACAGCTCCTCTGGCAATGTATCTGAAGGGGAAAGCCCTCCTGACAGCCAGGAGGACTCTTTCCAGGGAAGACAGAAATCAAAAGACAAAGCTGCCACTCCAAGAAAAGATGGTCCCAAACGTTCTGTACTGTCCAAGTCAGTTCCTGGGTACAAGCCAAAGGTCATTCCAAATGCTATATGTGGAATTTGTCTGAAGGGTAAGGAGTCCAACAAGAAAGGAAAGGCTGAATCACTTATACACTGCTCCCAATGTGAGAATAGTGGCCATCCTTCTTGCCTGGATATGACAATGGAGCTTGTTTCTATGATTAAGACCTACCCATGGCAGTGTATGGAATGTAAAACATGCATTATATGTGGACAACCCCACCATGAAGAAGAAATGATGTTCTGTGATATGTGTGACAGAGGTTATCATACTTTTTGTGTGGGCCTTGGTGCTATTCCATCAGGTCGCTGGATTTGTGACTGTTGTCAGCGGGCCCCCCCAACACCCAGGAAAGTGGGCAGAAGGGGGAAAAACAGCAAAGAGGGATAAAATAGTTTTTGACTCTAATACTGTATATGCATTTAAGTGGAATATTTGGTGCCATTTACAACATTATTTTCATGCCAATAAAAGATTTTTTTTGCAAATTA

Publications

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