Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PIGFP3
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:30017055-30017911  UCSC
Coordinates (T2T) chrX:29609235-29610091  UCSC
Coordinates (hg19) chrX:30035172-30036028  UCSC
Strand -
Parental Sequence NM_173074.3
Parental seq. overlap 539 bp
Parental seq. overlap (%) 34.4%
Genomic Region Intergenic
Retrocopy Summary PIGFP3, located on chrX:30017055-30017911, is a retrocopy of the parental gene PIGF. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PIGF
Full Name phosphatidylinositol glycan anchor biosynthesis class F
Also known as OORS
Coordinate chr2:46580937-46617057
Strand -
Gene summary This gene encodes a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PIGFP3
Bonobo Pan paniscus PIGFP3
Gorilla Gorilla gorilla PIGFP3
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PIGFP3
CATATGGCCCATCTCCTCCTATATGCTTGGAGCAAACTTTGGCAACATGGCTGGCCTTGTTATTTCACCACTCTGGATACACTGGAATAAAAAGCAACTTACATATAACAATTAACTGGAACAAAGGTAGAAGATATTTCTTTGTGCAGATACCATAAAGACTATGAAGAAATATATATAGTCAAAGCCAAACAGTTCCATTTACAGCATTGTTTTTTAAGAGAGTCAGATAGCCACCCAAGAAAACACAATGAAGGACACTGATATCAAGAGACTATTGTATAATCATCTTTTATGCATGTTTTCAATTAGCCTGATCATCTTCATTCCATCATTCTTTTTGGAGAACTTCTCAATATTGGAAGCACACTTAATACGGTTGTGCATCTGTTGTGTTTTTCTAACTGCTGTCAATCAAGTATTATATTTAGTAGTGAAGCCAAATGCATCCTCTAAAAGAAGTTTATTATCACACAAGGTGACCGGATTTTTGGAATGCTGTATTAATTTCTTATGCCTTGTTTCTTGCATGTAATTCATGTAATTTTTGTTCTATATGGAGAGCCACCATTAGAGTTGAAGATGGAAACATTTTTATTTGTGGTTATTTTGTCTGCTTTTACTACTCTACCAAGTTTATTTTTGTTAGGACCAAATCTCAAAGCATGGATAAGAGTTTTCACTGGAAAGGGAGTTATATTCACTTGGGAGAATAGTATCCAGATCAGTACAATTTCTAGTTTTGTGGGAACATGTCTTGGAGTACTTTCTATACCACTGGATTGAAAAAGACCATGGc
>NM_173074.3
CTGGGCCGCCCGTCGTACCTGATGGTAGGAGGCAGTAGTTCCCCGCTTCCCTTCCGCGGGAGGGAGAGTTAGCTAGCCATCCAAGAAAACACCATGAAAGATAACGATATCAAGAGACTACTGTATACCCATCTTTTATGCATATTTTCAATTATCCTAAGTGTCTTCATTCCATCACTCTTCTTGGAGAACTTCTCAATATTGGAAACACACTTGACATGGTTGTGCATCTGTTCTGGTTTTGTAACTGCTGTCAATCTAGTACTATATTTAGTAGTGAAACCAAATACATCCTCTAAAAGAAGTTCATTATCACACAAGGTAACTGGATTTTTGAAATGCtgtatctactttcttatgtcttgtttctcctttcatgtaatttttgttCTGTATGGAGCACCACTGATAGAGTTGGCATTGGAAACATTTTTATTTGCAGTTATTTTGTCTACTTTTACTACTGTGCCTTGCTTATGTTTGTTAGGACCAAACCTCAAAGCATGGCTAAGAGTGTTCAGTAGAAATGGAGTTACATCCATATGGGAGAATAGTCTCCAGATCACTACAATTTCTAGCTTTGTAGGAGCATGGCTTGGAGCACTTCCTATTCCACTGGATTGGGAAAGACCATGGCAGATGACAGTAGAAAGAAAACGtagcacttatagatctctccatgtaccctgcagggggcttggtactgtgaaatgagtaacttaatcctgacaaccgtagtgcaagGTATGGCCCATCTCCTGTACGCTTGGAGCGACCTTTGGCTACGTGGCTGGCCTTGTTATTTCACCACTCTGGATATACTGGAATAGAAAGCAACTTACATACAAGAACAATTAACTGGAGCAAAGGGAGATATTTCTTTGTGCAGATTCTGTAAGGGCTGGGCAGAAATGTGTATGGTCAAAGCCAAGCAGTTCCATTTACAGCTCTGTTTTTTACGTAGTTACAACATGATGTGATTGTAGCTTTTTAAACTATGAAACCCCTGAGAGATTGTACCTTCTAGTTGAAATAAAGTATTTATAATAGATTGTGGCTTCAGATGCTGCTTACTGCTTCTTAAACCTTTAAGGAACATTCTTAATACACTTTATAGAATTCTGAGGACAGGTTTTGTTTTCTTTCAAGTTTTGAACTGCTTCATTACCTATAAAAGGTCTGGGTATAGCTGTAGCATTTCATTTGCTTTCTGAGAGAAATGGACAGTTTCCTTGGCCACTGAAGATGTTTCTCACGTAATTAAACAACAGTTTATACATCTTGATCCTATTCTTTTTTTTACAGTGTGTTTCTTTGGAGTTAAAATGGCTATGATAGCCTCATCAAAAACAGTCTTCAATCCCTTCTGGGTTAAAGCTGAACATTCCACATAGCAGCA

Publications

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