Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name BAG1P1
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr9). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:38479251-38480763  UCSC
Coordinates (T2T) chrX:37882851-37884363  UCSC
Coordinates (hg19) chrX:38338504-38340016  UCSC
Strand +
Parental Sequence NM_001349299.2
Parental seq. overlap 1283 bp
Parental seq. overlap (%) 33.5%
Genomic Region Intergenic
Retrocopy Summary BAG1P1, located on chrX:38479251-38480763, is a retrocopy of the parental gene BAG1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name BAG1
Full Name BAG cochaperone 1
Also known as BAG-1|HAP|RAP46
Coordinate chr9:33252471-33264708
Strand -
Gene summary The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes BAG1P1
Bonobo Pan paniscus BAG1P1
Gorilla Gorilla gorilla BAG1P1
Orangutan Pongo abelii BAG1P1
Gibbon Nomascus leucogenys BAG1P1
Green monkey Chlorocebus sabaeus BAG1P1
Crab-eating macaque Macaca fascicularis BAG1P1
Rhesus Macaca mulatta BAG1P1
Baboon Papio anubis BAG1P1
Golden snub-nosed monkey Rhinopithecus roxellana BAG1P1
Marmoset Callithrix jacchus BAG1P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>BAG1P1
TGGAGCGAGAAGGTGACCAAGGAGGAAATGGTGGCAGCCAAGCTCAGCATGACCGTCACTCACAGCAATGAGAAGCATGACCTTCACGTTACCCTGCAGCAGGTCCAGCGGTGAACCAATTGCCCAAGACCTGACCCAGGTTGTTGGAGAGGCCACAGGGGTTCCACTGTCTTTTCAGAAACTCATATTTAAGGGAACATCTCTGAAGGAAATGGAGATACCTTTGTCAGCATGTGGAATACAAAATGGTTGCCAAGTCATGTTAATTGGGAAAAAGAACAGTCCAGAGGAAGAGGTTGAACTGGAGAAATTGAAAGAGTTGGTGAAGCCTGTGGAGAAGAAAGCTGACGAACTTTAAGAGTTGAATAAACAGCTTACTGGACTCCAGCAAGGTTTTCTGGCCAAGGATTTGCCAGCTGAAGCTCTCTGCAAACTTGGTAGGAGAGGAAAAGCCACAACCAAACAGTTTATGAAGATCTTGGAAGAGATCGACACACTGATCCTGCCAGAAAATTTCAAAGACAATAGATCAAAAAAGAAAGGTTTGGTaGTCAGACGTTCGTAGCTGAGTGTGGCACAGTGGAGCAGAACATCTGCCGGGAGACCCAGCAGCTGCAGTCTACAAACTTGGCCCTGGCTGAGTAAGGTGTGGCAGAAAGAGGCTGTGCTGCCCTGAAGAACAGCACCACCAGCTCTGCCCTCTCTGGAGCAGAATTTACCTGATTTATTCTAGGGACAACTGGCCTATTGCCAATTTTCCTATTCCTAGCCCAGTTCTCAGTGAAAAACTGTTGTCCTTGTGATCTTGAGTAGGGCGCTTGTCTGTTTTCTCATTGTGTCTCTGTGGCTGTGTGGTCCAGCAGCCTACTTTTTCTGGAGAGGGCCTCCCCTGCCCAGGTTTTCCCAGCTATTTGACCTTCTGGTGCTTTCTTTGGGCTGGTGAGATCTCTCCTTTGTCCTGAGCTAGTTCTAGGTTTATAGGCCACCCTGGTCTTCAGATACATGAGAGCTTTTTTGCTCTTGTGATCACACAGTCCCATAGATGTAAAACCAGAATCACTAGGAGGTTGCATTTATAATCAGGAATGTTGAGAATGGCTTAGAACAGGTGTTCGGCACATAGTAGTCCAAGTGTCCCTCATTGTGACTTAATTCCAGAACATCAGGCTGGGTTATTGGTTTATAGGCATTGTTCTTACCTTTTAGTGACCTGACTAGCCTCAAGACATGAAATATCAGGGGGCCATTCCTGGAATGAAGCGTATGGTTGATGCATGGACTTCCTCGTCCCCAGTAAAATCTTCAGAACCCAGTGTTGACTGAGTCCGTGCTTGAAACCAGGCATAGCAATGGCTTAGGCGGGGCAAAGAGGGGGAGCCACAATGAATAAAGCAGGCTGGTGGTGAAGCCAACCATAAATTTCCCAGGAATGACATGTGCTTCCTTCAAGGGCATTTCTGTTAAAAATACCCTTCTGAGATCTGTATTTCCTTCA
>NM_001349299.2
AGCTTCCATCGCTGGGCGGTCAACAAGTGCGGGCCTGGCTCAGCGCGGGGGGGCGCGGAGACCGCGAGGCGACCGGGAGCGGCTGGGTTCCCGGCTGCGCGCCCTTCGGCCAGGCCGGGAGCCGCGCCAGTCGGAGCCCCCGGCCCAGCGTGGTCCGCCTCCCTCTGGGCGTCCACCTGCCCGGAGTACTGCCAGCGGGCATGACCGACCCACCAGGGGCGCCGCCGCCGGCGCTCGCAGGCCGCGGATGAAGAAGAAAACCCGGCGCCGCTCGACCCGGAGCGAGGAGTTGACCCGGAGCGAGGAGTTGACCCTGAGTGAGGAAGCGACCTGGAGTGAAGAGGCGACCCAGAGTGAGGAGGCGACCCAGGGCGAAGAGATGAATCGGAGCCAGGAGGTGACCCGGGACGAGGAGTCGACCCGGAGCGAGGAGGTGACCAGGGAGGAAATGGCGGCAGCTGGGCTCACCGTGACTGTCACCCACAGCAATGAGAAGCACGACCTTCATGTTACCTCCCAGCAGGGCAGCAGTGAACCAGTTGTCCAAGACCTGGCCCAGGTTGTTGAAGAGGTCATAGGGGTTCCACAGTCTTTTCAGAAACTCATATTTAAGGGAAAATCTCTGAAGGAAATGGAAACACCGTTGTCAGCACTTGGAATACAAGATGGTTGCCGGGTCATGTTAATTGGGAAAAAGAACAGTCCACAGGAAGAGGTTGAACTAAAGAAGTTGAAACATTTGGAGAAGTCTGTGGAGAAGATAGCTGACCAGCTGGAAGAGTTGAATAAAGAGCTTACTGGAATCCAGCAGGGTTTTCTGCCCAAGGATTTGCAAGCTGAAGCTCTCTGCAAACTTGATAGGAGAGTAAAAGCCACAATAGAGCAGTTTATGAAGATCTTGGAGGAGATTGACACACTGATCCTGCCAGAAAATTTCAAAGACAGTAGATTGAAAAGGAAAGGCTTGGTAAAAAAGGTTCAGGCATTCCTAGCCGAGTGTGACACAGTGGAGCAGAACATCTGCCAGGAGACTGAGCGGCTGCAGTCTACAAACTTTGCCCTGGCCGAGTGAGGTGTAGCAGAAAAAGGCTGTGCTGCCCTGAAGAATGGCGCCACCAGCTCTGCCGTCTCTGGAGCGGAATTTACCTGATTTCTTCAGGGCTGCTGGGGGCAACTGGCCATTTGCCAATTTTCCTACTCTCACACTGGTTCTCAATGAAAAATAGTGTCTTTGTGATTTTGAGTAAAGCTCCTATCTGTTTTCTCCTTCTGTCTCTGTGGTTGTACTGTCCAGCAATCCACCTTTTCTGGAGAGGGCCACCTCTGCCCAAATTTTCCCAGCTGTTTGGACCTCTGGGTGCTTTCTTTGGGCTGGTGAGAGCTCTAATTTGCCTTGGGCCAGTTTCAGGTTTATAGGCCCCCTCAGTCTTCAGATACATGAGGGCTTCTTTGCTCTTGTGATCGTGTAGTCCCATAGCTGTAAAACCAGAATCACCAGGAGGTTGCACCTAGTCAGGAATATTGGGAATGGCCTAGAACAAGGTGTTTGGCACATAAGTAGACCACTTATCCCTCATTGTGACCTAATTCCAGAGCATCTGGCTGGGTTGTTGGGTTCTAGACTTTGTCCTCACCTCCCAGTGACCCTGACTAGCCACAGGCCATGAGATACCAGGGGGCCGTTCCTTGGATGGAGCCTGTGGTTGATGCAAGGCTTCCTTGTCCCCAAGCAAGTCTTCAGAAGGTTAGAACCCAGTGTTGACTGAGTCTGTGCTTGAAACCAGGCCAGAGCCATGGATTAGGAAGGGCAAAGAGAAGGCACCAGAATGAGTAAAGCAGGCAGGTGGTGAAGCCAACCATAAACTTCTCAGGAGTGACATGTGCTTCCTTCAAAGGCATTTTTGTTAACCATATCCTTCTGAGTTCTATGTTTCCTTCACAGCTGTTCTATCCATTTTGTGGACTGTCCCCCACCCCCACCCCATCATTGTTTTTAAAAAATTAAggcctggcgcagcagctcatgcctataatcccagcactttgggaggctgaggcgggcggatcacttgaggccaggagtttgagaccagcccaggcaacatagcaaaaccccattctgctttaaaaaaaaaaaaaaaaaaaattagcttggcgtagtggcatgtgcctataatcccagctactggggaggctgaggcacaagaatcatttgaacctgggaggtagaggttgctgtgagccgagattacgcccctgcactccagcctgggtcacagagtgagactccatctcagaaaaaaaaaaaaTTGAgtcaggtgcagtagctccttcctgtagtcccagctacttgggaggctgaggctagaggatcacttgagcccaggagtttgagtctagtctgggcaacatagcaagaccccatctctaaaaTTTAAGTAAGTAAAAGTAGATAAATAAAAAGAAAAAAAAACTGTTTATGTGCTCATCATAAAGTAGAAGAGTGGTTTGCTTTTTTTTTTTTTTTTGGATTAATGAGGAAATCATTCTGTGGCTCTAGTCATAATTTATGCTTAATAACATTGATAGTAGCCCTTTGCGCTATAACTCTACCTAAAGACTCACATCATTTGGCAGAGAGAGAGTCGTTGAAGTCCCAGGAATTCAGGACTGGGCAGGTTAAGACCTCAGACAAGGTAGTAGAGGTAGACTTGTGGACAAGGCTCGGGTCCCAGCCCACCGCACCCCAACTTTAATCAGAGTGGTTCACTATTGATCTATTTTTGTGTGATAGCTGTGTGGCGTGGGCCAcaacatttaatgagaagttactgtgcaccaaactgccgaacaccattctaaactattcatatatattagtcatttaattcttacataacttgagaggtagacagatatccttattttagagatgaggaaaccaagagaacttaggtcattagcgcaaggttgtagagtaagcggcaaagccaagacacaaagctgggtggtttggtttcagagccagtgcttttcccctctactgtactgCCTCTCAACCAACACAGGGTTGCACAGGCCCATTCTCTGATTTTTTTCCTCTTGTCCTCTGCCtctccctctagctcccacttcctctctgctctagttcattttctttagagcagcccgagtgatcatgaagtgcaaatcttgccatgtcagtcccctgcttagaaccctccaatggctcactttctctttaggcaaaagtctttaccccatgccttctcccatctcatctcaaccccctcatttgttggctgtctgctgtcagccactcttctttcaggtcctcagatgcactgcaccctctcctgcctgggggtctttgctcctgctactacctctgcttgaacagctcctcaccttccttcctccaaccctacccttgtataggtgacttttgttcatccttcagaattcaactcacatgtctcttgcatggagaaccctcacctactgtgttgagaccctgtccagcccccaggtgggatcctctctcgacttcccatacatttctttcacagcatttacatagtccatgatagtttacttgtgggattatttggttaatctttgcctttaacaccagggttccttgggtgaaggagcttctttatcttggtaACAGCATTATTTCAAGCATAACTTGTAatatagttatattacatatataacatatatatatataacataacatatataacatatataacaAGCATAACTTGTTATATAgtcttgtatatagtaagacctcaataaatatttggagaacaaa

Publications

PMID - Link Title