Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CLIC4P3
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:41076907-41078576  UCSC
Coordinates (T2T) chrX:40478926-40480596  UCSC
Coordinates (hg19) chrX:40936160-40937829  UCSC
Strand +
Parental Sequence NM_013943.3
Parental seq. overlap 1209 bp
Parental seq. overlap (%) 28.4%
Genomic Region Intergenic
Retrocopy Summary CLIC4P3, located on chrX:41076907-41078576, is a retrocopy of the parental gene CLIC4. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CLIC4
Full Name chloride intracellular channel 4
Also known as CLIC4L|H1|MTCLIC|huH1|p64H1
Coordinate chr1:24745447-24844321
Strand +
Gene summary Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells). [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CLIC4P4
Bonobo Pan paniscus CLIC4P4
Gorilla Gorilla gorilla CLIC4P3
Orangutan Pongo abelii CLIC4P4
Gibbon Nomascus leucogenys CLIC4P3
Green monkey Chlorocebus sabaeus CLIC4P4
Crab-eating macaque Macaca fascicularis CLIC4P4
Rhesus Macaca mulatta CLIC4P4
Baboon Papio anubis CLIC4P4
Golden snub-nosed monkey Rhinopithecus roxellana CLIC4P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CLIC4P3
GCGGCGGGAGCCGGCAGTCGGAGCAGCCTTGGCGTCGCCGTTTGCGGAGCGCAGCCGAGCCGGCCATGGCGTTGTCGATGCCGTTGAACGGGCTGAAGGAGGAGGACAAAGAGCCCCTCATTGAGCTCCTCGTCAAAGCTGGCAGTGATGGTGAAAGCATAGGAAACTGCCCCTTTTCCCAGAGGTTCTTCATGATTCGTTGACTCAAAGGAGTTGTATTTAGTGTCACAACTGTTGACCTGAAATGGAAGCCTGCAGACCTACAGAACTTAGCTCCCAGGACCCACCCACCGTTTGTAAGTTTCAACAGTGAAGTCAAAACGGATGTAAGTAAGATTGAGGAATTTCTTGAAGAAGTCTTATGCCCTCCCAAGTACTTAAAGCTTTCACCAAAACACCCAGAATCAAATACTGCTGGAATGGACATCTTTGCCAAATTCTCTGCATTTATCAAGAATTGAAGGCGAGAGGCTAATGAAGCACTGGAGAAGGATCTCCTGAAAACCCTGCAGAAACTGGATAAATATCTGAATTCTCCTCTCCCTGATGAAATTGATGAAAATAGTATAGAGGACATTAAGTTTTCTACACATAAATTTCTGGATGGCAATGAAATGACATTAGCTGATTGCAGCCTGCTCCCCAAACTGCATATTGTCAAGGTGGTGGCCAAAAAATATCACAACTTTGATATTCCAAAAGAGATGACTGGCATCTGGAGATACCTAACTAATGCATATAGTAGGGACGAGTTCATCAATACCTGTCCCAGTGATAAGGAGGTTGAAATAGCATATAGTGATGCCAAAAGACCCACCAAGTAAAATTGCATTTATGAAAGAGATGTCTTCATGTCTTCCCCTAAGAATATGCTTTTCCTAACAGGCTACTCTTCTTCTTATAGAGTAGAAATTGTATTTTGCACGAACATGCAGTTATTGAGGATTAGGATCAAGGGTAGACAAGGTATAGTAGTTATCTTAAAATATACACTCCTTcTCCTAAGCAGTATTATTTTAAAATCCTTTTACCCTGCCTACCTCTGTACCCGTGTTCCCCTCTTTTTAATTTGGAGACACTCCACCACAAACTTTTCACTTTAGAGGTAGCTTGCCATCTTTCAGGAGCCCTCACCATTGTGTCTATTCACTGTGCATAGATGACAGAATTTTGAGGTGCAATGTCTGTTTAAATAGTAGCTACGACTTTATCAGGCAACCCCAAACTGGTGCATAATGCATGGTATAAGGAATATTTATGTATTTTTTGGATTTTTGTAATATTTAGT
>NM_013943.3
AGTCcagcgagcagcacggcgggaaccggcagccggagcagtcccggagcagaagcagcagcagcagcagcagcCCTCGCCGTTCGCGGAGCGCAGCCGAGCCGGCCATGGCGTTGTCGATGCCGCTGAATGGGCTGAAGGAGGAGGACAAAGAGCCCCTCATCGAGCTCTTCGTCAAGGCTGGCAGTGATGGTGAAAGCATAGGAAACTGCCCCTTTTCCCAGAGGCTCTTCATGATTCTTTGGCTCAAAGGAGTTGTATTTAGTGTGACGACTGTTGACCTGAAAAGGAAGCCAGCAGACCTGCAGAACTTGGCTCCCGGGACCCACCCACCATTTATAACTTTCAACAGTGAAGTCAAAACGGATGTAAATAAGATTGAGGAATTTCTTGAAGAAGTCTTATGCCCTCCCAAGTACTTAAAGCTTTCACCAAAACACCCAGAATCAAATACTGCTGGAATGGACATCTTTGCCAAATTCTCTGCATATATCAAGAATTCAAGGCCAGAGGCTAATGAAGCACTGGAGAGGGGTCTCCTGAAAACCCTGCAGAAACTGGATGAATATCTGAATTCTCCTCTCCCTGATGAAATTGATGAAAATAGTATGGAGGACATAAAGTTTTCTACACGTAAATTTCTGGATGGCAATGAAATGACATTAGCTGATTGCAACCTGCTGCCCAAACTGCATATTGTCAAGGTGGTGGCCAAAAAATATCGCAACTTTGATATTCCAAAAGAAATGACTGGCATCTGGAGATACCTAACTAATGCATACAGTAGGGACGAGTTCACCAATACCTGTCCCAGTGATAAGGAGGTTGAAATAGCATATAGTGATGTAGCCAAAAGACTCACCAAGTAAAATCGCGTTTGTAAAAGAGATGTCTTCATGTCTTCCCCTAAGAATACGCTTTTCCTAACAGGCTACTCCTTCCTGTAGAGCAGAAATTGTATTTTGCACGAACATGCAGTTATTGAAGATTAGGATCAAGGATAGACAAGGTATAGTAGTTATCTTAAAATATACACTCCTAAGCAGTATTATTTTAAAATCCTTTACCCTGGCTACCTCCCCTACCCGGGTTCCCCTCTCTTTAATTTGGAGACACTCCACCACAAACTTTTCACTTTAGAGGTAGCTTGCCATCTCTCAGGAGCCCTCACCATTGTGTCCATTCACTGTGTATAGATGGCAGAACTTTTGAGGTGCAATGTTTAATTGTTAAAAATAGTAGCCACGACTTTATCAGGCAGCCCCAAACTGGTGCATAATGCATGGTACAAGAAATATTTATGTATTTTTTGGAATTTTGTAATATTTAGTAAGAGTATATGAAAGGATTGCTACTGTATCAGAAATATTGTTTCAATTTAGTCTATCCTGGATATGTACTAACGAATATTACCACCAGAGAAGAGAGCTTTCTACAAAAGTCACTACAGATTTTGCTATATTGCTTTGTAGATAGATTTTTACTTTTGCCTAAAAGCATTTATCCTTCATACCAATTGTAACATCTGACACCATGTAGAAGCTAAAAGTTTAGAGGGAGTGAGGGTTTTCTCAAGACCTTCCTCAAGCATTTTATCTTTAGAAGAGAAACTGATGGGCACCTGATACTCTGTCTAAATACGTTTGTTATATGTGTTTTGCCCTGTGCCATTCATTTGGAACTTTATTGCATTCTTTATTTTAAAAAGCTTGTTTTTACGTAATCATAGAGCTTGCTATTTGTACATCTGTTGAGCAACACTACATAACTGATTTTTAGTTGACTTAGCTATAGCAGTACAATGATTAGTAATGTAAAAATTAACACAGAAATTAACCTAAGGAATGAAGGGTGGGTTTGTCAAAATATCAAGTAAATTTTTGTTTCTAAAGTACATTTAATGTAGATGACCTAAAGAATGCGTTATCCATCCTATATAAAAGAAAGATAAAACACAGGTCACCAATTTTCTCATTTCACCCCATTTACCTTGTATAGAGGATTGTTCATTCCTTTGGGACTAAGTTATAGTTATGGTGAGTGTGTATTTACTGTAGTTTTGCCTGATCTCACTCATTGCACTTCCTGGAGTTAAATTTTCCAACAGCCATGTTGAGGAATAGCACTCTGCATGTTTTTGTTTTGTTTTTCGGGGTTTTTTTTAATTGAAGCCCTAAACCAGGAATTATTTGTGTTCTAACAGGAGGATGAACTTGCTGAAAATAAAACTTTGCTATGTATTTACTCTTTTTTAAAAGACAAAAGCAAAACCAGACTTTCTACGTACTACTCCAAAGACTGTGATTGTGACTATAATACATTTTTGGTAATTTTTTTATACCTAATTTGTATAGGAAGTGCTATTTCTCATAGGCTGTTTCTTGAAATTTTAAGTTTATTGCTTTAAAATGGCAGTGTTTCTCCCACTTTGATATGCTAACATTTAGTAAGCACTGGCTTTATGAAAGCGGCTTTTTATAAGTATACTGCATTTTTTGAGCCTATCATTAATTAGCTTAGTATGAAAGATAAGAAAATCTCCATGTTGTATCCATTTGGCTCAGGAAGATTCTTTGCCTTACCTTTCTTAGAACTCTTTATTGCTTATCAAAAGTTTGAGTACCCGCTTGGTTTTTTTTTGGTAATTAAATATTGTATGATTTATCTGGTTCAAGGAAGATGCACTATTCAGTTATCTATTGAGAAATTATTTTGCAGTGGTTTTAGTGGGTGAAAATGTCCCATCTGCACCAGTACACAGGCAGGCATTATCATTCTTCACCTACTTTTTAAATAGTGGCAACTTGGGATTCATTCTGGTGATTCTGAACCTTGCCTCATAGCTTAAAGTATAAAAAAGATTCAAGAGCAGTGAGGTTTGTTCTTTCCAGTGAATGGTGGACTGAGTGGTGCGAGGTGGAGGGCTAACAAGAGGAAAGAACTACATTCTTCAGAATACAGTGATGAAAATTCATTTTGAAACTCAAATATTTTCATTTTGGATATTCTCCTGTTTTTATTAAACCAGTGATTACACCTGGCCATCCCTCTAAATGTTCTAGGAAGGCATGTCTATTGTGATTTTGATGAAGACAGAATTATTTTTCTCTGTAGAAACACAGATACCACTTTATCAGGGAAGTTAGTCAAATGAAATGGAAATTGGTAAATGGACAAAAGCTAGCTAGTAAAAAGGACGACCCAGCAACATGCTTTAACCCCATTGTATGTTTGTGGAAAGAGCATAGTTTAACATCTTGAGAAATTTGGGACATAAAGTTTTCATGGTAGACAGTTCATGCAGTATATGAATTGCCATAATGGAAATAATCTGATTTTATTTTTACAACTAACATCCATTCCCCTTCATTTAAACACCTTTTGTGTTTTACTTCAGTGAGGAGATTGGAGTCTGAATGGATCTGTTTTCCAAGAGATTCTGAGAAATTTTTGTATTCAGCAGTTGGAAAGCTCTCTATTCTAGTTGATAAAACTTCCCTTTTTTGATGTAGATGCAGATATTCTATACAGTTCTGTTGTCTTTTACTAGGACTGTAAACTTTTGTGATAAAATTCAAATAAGATTTTATTTCTTGGTAATTTTGGCTTTCACAATTTATCTTTAAATCCTTGAGCAATCTGTATACAATTAAGAGATTTCTGACATTTATTCTTACACTAAATGGATCAACTCTAGGATTTAGGCATGTTAACTTCTGTTGTGTTTTGAATCTCTCCAGAGTTGCATGTAGATAGCATTTATTTCTGTGCCCTTAAACCCATTTAGAAAATAACTACAAAGTAAAAATGTAGAGGAAATAGAAATGTATTTTTTCATGAACATTTTGATACAAATTTCATCATTTAATGATTCACCAATTTCTTGCATTAATTTGAATTTAAGCATTTAATTCAAAGAGAGGGGAGCATCCATTATTGATACATGTGGGCTTTTAAAAACTCCATCCTTTATAAATAGTCAAGGTTTGGGCCACACAAAGTATATTTTTATCATGGAAAAATTTCAACTCCTCAAGCCGTAATGTTGAACAGAATTGGAGTATTTTCTTTATAATTTCTTGAACAGGCAAATGAAAGCTTATTATAGAATGCATGTATTTTCTTTTATCTTTGGAACATCAGCACCAGTATATTGCTGGCAGCTATTGTATTAAAAAATAAAGTATATTTTCACTATCATAAAGGATTCTTTTTTCCCCCCTCATGAAAATAAACAACAACTTGGGGTAAAA

Publications

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