Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NICN2P
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr3). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:47272140-47274462  UCSC
Coordinates (T2T) chrX:46681778-46684100  UCSC
Coordinates (hg19) chrX:47131539-47133861  UCSC
Strand -
Parental Sequence NM_032316.3
Parental seq. overlap 1650 bp
Parental seq. overlap (%) 50.2%
Genomic Region Intergenic
Retrocopy Summary NICN2P, located on chrX:47272140-47274462, is a retrocopy of the parental gene NICN1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NICN1
Full Name nicolin 1, tubulin polyglutamylase complex subunit
Also known as -
Coordinate chr3:49422333-49429324
Strand -
Gene summary This protein encoded by this gene localizes to the nucleus and is expressed in numerous tissues including brain, testis, liver, and kidney. This refseq contains genomic sequence in its 3' UTR which is not supported by experimental evidence. Computer predictions indicate that this region of the 3' UTR contains hairpin-forming self-complementary sequence which is possibly excised after transcription. This gene has a pseudogene on chromosome X. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes NICN1P1
Bonobo Pan paniscus NICN1P1
Gorilla Gorilla gorilla NICN1P1
Orangutan Pongo abelii NICN1P1
Gibbon Nomascus leucogenys NICN1P1
Crab-eating macaque Macaca fascicularis NICN1P1
Rhesus Macaca mulatta NICN1P1
Baboon Papio anubis NICN1P1
Golden snub-nosed monkey Rhinopithecus roxellana NICN1P1
Green monkey Chlorocebus sabaeus Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NICN2P
TTACTACACAGCTTTTTTGAGCATCCTGTCTGTCAGCACACCTCAGCACACACACCGGCCAAGTGGGTGACCTGCCTGTGGGACTACTGTCTGATGCCCAACCCACACAGTGAGGAGGGAGCCCAGGAGTATGTGTCGCTGTTCAAGCAACAGATACTGTGTGACATGGCCAGAATATCGGAGCTACACCTGATTCTGCAGCAGCCATCACCACTGTGGCTGTCTTTCACAGTGGAGGAGCTGCAGATCTATCAGCAGGGACCAAAGAGCCCCTCCATGATCTTCCCCAAGTGGCTCTCCCACCCAGTGCCCTGTGAGCAACCTGCACTCCTCCATGAGGGTCTCCCAGACCCCAGCAGGGTATCCTCTGAGGTGCAGCAGATGTGGGCACTGACAGAGATGATCCGGGCCAGTCACACCTCCGCGAGGATAGGCCACTTTGATGTAGATGGCTGTTATGACCTGAACTTACTCTCCTACACTTGAGTGGTGGCTCCTAGCCAAGATGTTGGCCTTTCTGTGCCCACTCAGACTTGGTTTGGGCCACCAGAGGCCGAAATGTGTTTTCTGTGCATTCCAAGTGTTGCCTGCATGCCTGTTCTGTCTGGGCAGCATTCACAGATTCAAGATTCTCCGGGGCTGACTGTGTTGCTTCAGCATGAGCTCCTGGCAAGGGGGCACTCTGTCTTCACCTGGCTGCAACTCAGTTCTTCCTTCTACCCAAAAACACTCCAGTCAGTTGTACTTACTAAGAATCCCTGAGTGCCCTCTGCCCCTCCTGCCAACATGCACTCTCCTGTCTTCTGCCTGCTCCTTCACCTCAGTGCAGTTGGGCTGGGCTGACCTACTAGAACGTGCTCCATGTATGGACCCAGAAGGCCATTGCTGCCATGGCACTTGGGATACTTGAGGAAGAAACAGAAACCTTATTTCTTCCTGTGTGTCCCCTAGTGACTTTCTTTCCCTTTGTGTTATGCCATAAAAAGAAAATTTCCTGTCTAAACTCTTCTGCTGCCTGCCTAGGAAGCAAAGCTGAAGATTTGGGCAGCCTGAGTCTCTCAGTTTCTGAGCTGGCTCCTGAATATATGTCCAAATGGGTGTGCCCATAGGGCCTCGGCAGGTGTCTCTAGCAAAGCCAGGGCCTGAGAATAAGAACTGGGATCTGTCTGCCATCTGACATAGCCCAAAGCACATTCCTATCCTTTCTCCCAGTTGCCCCTTTCCAAGAGACATGCTCAGCATGATGAGAGATCAACCATGGTGGGGAATGGGTCCAAGTAAGGGTTCTCATTGGTGCCTTTTAAGAGGCCTAGGTCCTCCATTAACTCAGGCCAACCATTAAGTGATGCAGGCTGCTCTTCCTTCATGTGAGAAAACCCTGTTTCCCTCTGGTTCTTCCTGGCTTCACCCCTGGTGGCTATTATAAAGCAGTACTGTTGTATGTCTTGGACCTGGAAAACTGGACATGTGTGCGACTCAACAGTTTTCTTGGGGGAGTTCAGTGACCTTTTGGTGGTCACCCTCTGCTCTCATCCATGAGTTCTTACATAGCCCCATTCAGCTGCTTCTGAAAGGGTGATGGAACAGTAGTCCTCAGTGTGTGTGTGAGTGAAGAGGACCTTGGATGGCAGGAAGGGCTGGAGGTCGGGGCCTGGAGCAGCTATTGCACTTAATCGCGGCTGCTAGCACCATGTCCCGCGTTTTGGTGCCTTGCCATGTGAAAGGCACCGTAGCCCTGCAGGTGGGGGACGTATGGACCTCCCAAGGCCGGCCTAGTGTGCTGGTCATTGATGTCACCTTCCCCTGTGTCACTCCGTTCGAGGGGATCACATTTAAGAATTATTACACAGC
>NM_032316.3
CTTGAGGCTCGGCTGAGGATGCCGGGAAGGGCTGGTGGTCGGGGGCCTAGAGCGGCGGTTGCACTTAGTTGCGGCTGCTGTCACCATGTCCCGCGTTTTGGTGCCTTGCCATGTGAAAGGCTCCGTAGCCCTCCAGGTGGGCGACGTGCGGACCTCCCAAGGCCGGCCTGGCGTGCTGGTCATCGATGTCACCTTCCCCAGCGTCGCTCCCTTCGAGTTGCAGGAAATCACGTTTAAGAATTACTACACAGCTTTTTTGAGCATCCGTGTCCGTCAGTACACCTCAGCACACACACCTGCCAAGTGGGTGACCTGCCTGCGGGACTACTGCCTAATGCCTGACCCACACAGTGAGGAGGGAGCCCAGGAGTATGTATCGCTGTTCAAGCATCAGATGCTGTGTGACATGGCTAGAATATCGGAGCTACGCCTGATTCTGCGGCAGCCATCACCACTGTGGCTGTCTTTCACAGTGGAGGAGCTGCAGATCTATCAGCAGGGACCAAAGAGCCCCTCCGTGACCTTTCCCAAGTGGCTCTCCCACCCAGTGCCCTGTGAGCAACCTGCACTCCTCCGTGAGGGTCTCCCAGACCCCAGCAGGGTATCCTCCGAGGTGCAGCAGATGTGGGCACTGACAGAGATGATCCGGGCCAGTCACACCTCCGCAAGGATCGGCCGCTTTGATGTGGATGGCTGTTATGACCTGAACTTGCTCTCCTACACTTGAATGGTTGCTCCTAGCCAAGATGTTGGCCTTTCTGTGCCCACCCAGACTTGGTTTGGGCCACCAGAGGCTGAAGTGTATTTCCTGTGCATTCCAAGTGTTGCCTGCATGCCTGTTCTGTCTGGGCCACATTCACAGATTCAGGATTCTCAGGGGCTTACCGTGTTACTTCAGCATGAGCTCCTGGCATGGGGGTGCTCTGTCTTCGCCTGGCTGCAACTCAATTCTTCCTTCTACCCAAAAACACTCCAGTCAGTTGTACTTACTGAGAATCCCTGAGTGCCCTCTGCCCCTTCTGGCAACATGCACATTCCTGTCTTCTGCCTGCTCCCTCATGTCAGTGCAGTTGGGCTGGGCTGACCTACTAAAACCTGCTCCATGTATGGACCTGGAAGGCCATTGCTGCCATGGCACTTGGGACACTTGAGGAAGAAACAGAAACCTTATTTCTTCCTGTGTGTCCCCTAGTGGTTTTCTTTCCATTTGTGTTATGCCACAGAGAGAAATTTCCTGTCTGAACTCTTCTGCTGCCTGCCTAGGAAGGAAACCTGAAGATTTGGGCAGCCTGAGTCTCTTGGTTTCTGAGCTGGCTCCTGAATATATGTTCAAGTGGGTGTGCCCATAGGGCCTGGGCACGTGTCTCTAGCAAAACCAGGGCCTGAGCATAAGAACTGGGACCCTTCTAggcagggtgcagtggctcacgcctgtaatcccagcactttgggaggcccaggcaggcggatcacctgaggtcaggagttcaagaccagcctgaccaacctggagaaaccccgtctctactaaaaatacaaaaaattagctgggcgtggtggtaggcacctgtaatcccagctacttgggaggctgaggcaggagaatctcttgaacccgggaagtggaggttgcggacctgagatcatgccattgcactccagcctgggcaagaagagcgaaactccatcttaaacaaacaaacaaaaaaaaaagaaCTGGGACCCTTCTGCCATCTGACATAGCCCAAAGCACATCTCTATCCTTTCTCCCAGTTGCCCCTCTCCttttttgttgttttttttgaggttgagttttgctcttgttgcccaggctggagtgcaatagtgcaatcttggctaactgcaacctccgcctcccaggttcaagcaattctcctgcctcagtctcccgagtagctgggattacagtcatgcatcaccatgcctggctaattttgtatttgtagtagagatggggtttctccatgttggtcaggctggtctcaaacacctgacctcaggtgatctgcctgccttggccttccaaagtgctgggattacaggcatgagccaccgcgcccgcccTGCCCCTTTCCAAGAGATATGCTCAGCATAATGAGAGATCAACCGTGGTGGGGAGTGGGTCCAAGTAAGGGTTCTCATTGTTGCCTTTTAAGAGGCCTAAGTCCTGCATTAACTCAGTCCAACCATTAAGTGATGCAGGCTGCTCTTCCCTCATGTGAGAAAAACCTGTTTCCCTCTGGTTCTTCCTGGCTTTGCACCTGGTGGCTATTACAAAGCAGTACTGCAGTATGTCTTGGACCTGGAAAGTTGGACATGTGTGTGGCTCAACAGTTTTCTCGGGGGAGTTCAGTGACCTTTTGGTGGCCACCCTCTGTTCTCACCTGTGAGTTCTTGCAGGTGGCGACTTCATCTGCAAGGTCACTTACATAGCCCCACTCAGCTGCTTCGGAAAGCGTGACGAAGCAGTAGTCCTCAGTGTGTGTGTAAGTGAAGAGGAccttgtggtagcagggaccatgcttcattcgtggctgtgtccccatctgagggcctggtatgcagtaagatcaataaatacttgtggaatgcatgaCTGCTGGCTGCCTGTGTCTGCCTGGTGGGAGAGCTGTGGAACTAGGGGTCCACATGAGGACAGACTACTGTGGTGCTGCCTACCTGCCAGGCTGGCCCACCTTCCCCACCCCCACTTGACCTTACTCTCTTGAGGTCCTAAAGGTATGATTCAGACCTTTCAGCCCTTTCCAGAACTTTGACCCTCTGGAGACAGGGCGGTTCTGCAGGGGGCGGTCTAGCCCCTAGCTTTGTTCTGGGCAGCCCAATCAGCTCTGGATTGCCCGAGCTGCCCTGAAGAGTCAGCCGAAAGAGCTGGAGGCTTCTTCCCTGTGGTTGCGGGTTCCTGCATTCTCTGCTCTAAATCCCAGCCTGCCCTTGGGGCTGCCCACGCCCCCTTCAGATCCTTTGCTCCGGAGAGAGACCTGTCCGAGCAGAGGCCTGGACTACATCTCCCGGCGTGCCTGGCAGTGTGGTGGCCTCTGTGCGCCGTCTGCACTCGTTGCAGGCGACGATGCAGAGGGCTGTAAGTGTGGTGGCCCGTCTGGGCTTTCGCCTGCAGGCATTCCCCCCGGCCTTGTGTCGTCCACTTAGTTGCGCACAGGTGGGATAGAGGGTGCTGATCTTGGAGG

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