Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TIPINP1
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr15). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:53455103-53457039  UCSC
Coordinates (T2T) chrX:52741446-52743383  UCSC
Coordinates (hg19) chrX:53482050-53483986  UCSC
Strand -
Parental Sequence XM_006720594.3
Parental seq. overlap 903 bp
Parental seq. overlap (%) 43.4%
Genomic Region Intergenic
Retrocopy Summary TIPINP1, located on chrX:53455103-53457039, is a retrocopy of the parental gene TIPIN. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TIPIN
Full Name TIMELESS interacting protein
Also known as -
Coordinate chr15:66334974-66387273
Strand -
Gene summary The protein encoded by this gene is part of the replisome complex, a group of proteins that support DNA replication. It binds TIM, which is involved in circadian rhythm regulation, and aids in protecting cells against DNA damage and stress. Two pseudogenes and two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TIPINP2
Bonobo Pan paniscus TIPINP2
Gorilla Gorilla gorilla TIPINP2
Orangutan Pongo abelii TIPINP3
Green monkey Chlorocebus sabaeus TIPINP3
Crab-eating macaque Macaca fascicularis TIPINP3
Rhesus Macaca mulatta TIPINP3
Baboon Papio anubis TIPINP3
Golden snub-nosed monkey Rhinopithecus roxellana TIPINP1
Gibbon Nomascus leucogenys Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TIPINP1
GTGCAACAGTAACTTGATGCTTCATCCAGAAATGCTACTGAAGCTAGATAGGTTTCCATTAAGAGAAAATGTATCTGTTAACTCCCCATTCTGCAAGCTTGGCGTTACTATGTATTTTTTCTTCTTTGAGTGAAAATCCTTAGGTAGTAAAACTTTTATAGATTACTATTTAAAATCTGGTAATCTGGTATTTATTTATAAGTATGCCTGTCACTTTAGTTGTCTGTTCTCTTTAGTGTTTGTTTTTATACAGATATGACTTCATAAAATGATTATTAGGTAATAAGCAGTTTCTGCTGCTGGTCTGCCATTGAATGCCTTGTTTTCACTAAATTGGGAGATTTTGTTGTTGTTTTTCAGAGGAAAAGATGCTAGAATCACAGGAGAATGGCATGATTGACCTTCCAGATTATGAGCATGTAGAAGATGAAACTTTTCCTCCTTTCCCACCTCCAGCCTCTCCAGAGAGACAAGATGATGAAGGAGCTGAACCTGATAGTCAGGAAGTGGAGCACTTGTTCCTGTACCTCCAAAGAGAGCAGTTAAAAGAAATATATCCGAGCTGGATGCTCACAGATTAATTTCAGAGAGAGGGCTTCCAGCCTTAAGGCATGTATTTGATAAGGCAAAATTCAAAGGTAAAAGTCATGAGGCTGAAGACTTAAAGATGCTAATCAGACACATGGAACACTGGGCACGTAGGCGATTCCCTAAACTGCAGTTTGAGGATTTTATTGACAGAGTTGAATACCTGAGAAATAAAAAGGAAATTCAGACCTGTTTAAAATGAATTCGACTTGATCTCCCTATTTTACATGAATATGTTGTTAGCAATAATGAGGAAGTTGGGGAAAATAATGGACATTGTGTAACTGCTACTGAATTAGATCCCTTTCTGACAAACTCATCTGAAAGTGAGATGTTTGCTTCTGAGTCAAGTAGAAGCCTAACAGATGAGCAACAACAAAGGATTGAGAGAAATAAACAACCGGCTTTGGAAAGAAGGCAGGCAAAGCTGCTGAGTAATAGTCCCTAGGAAATGATAATGTTAATGAATACACCCAGGGTACAGACAATTGAAGAGGTTAATACTGATGAAGATCAAAAGGAGGAGTCAAATGGATTAAACAACGACATTCTAGACAATCTATGTAATGATGCTCCTGCCAATACTTTAAATGAAGAGAATGATTTAACATGAGAGGAAACACAGCTGGACCAGTCTTTTAAAAATGTGCAACAGTg
>XM_006720594.3
atgaagaagccctaggatggagtcttggatacttaatggccggggtagaagataaacctgcaaagaaaatccaggaggagtgcccagaaagggaggaaagcctcagcctcctgagtagctgggactacagAGGAAAAGATGCTAGAACCACAGGAGAATGGCGTGATTGACCTACCAGATTATGAGCATGTAGAAGATGAAACTTTTCCTCCTTTCCCACCTCCAGCCTCTCCAGAGAGACAAGATGGTGAAGGAACTGAGCCTGATGAAGAGTCAGGAAATGGAGCACCTGTTCGTGTACCTCCAAAGAGAACAGTTAAAAGAAATATACCCAAGCTGGATGCTCAGAGATTAATTTCAGAGAGAGGACTTCCAGCCTTAAGGCATGTATTTGATAAGGCAAAATTCAAAGGTAAAGGTCATGAGGCTGAAGACTTGAAGATGCTAATCAGACACATGGAGCACTGGGCACATAGGCTATTCCCTAAACTGCAGTTTGAGGATTTTATTGACAGAGTTGAATACCTGGGAAGTAAAAAGGAAGTTCAGACCTGTTTAAAACGAATTCGACTTGATCTCCCTATTTTACATGAAGATTTTGTTAGCAATAATGATGAAGTTGCGGAGAATAATGAACATGATGTCACTTCTACTGAATTAGATCCCTTTCTGACAAACTTATCTGAAAGTGAGATGTTTGCTTCTGAGTTAAGTAGAAGCCTAACAGAAGAGCAACAACAAAGAATTGAGAGAAATAAACAACTGGCCTTGGAAAGAAGGCAGGCAAAGCTGCTGAGTAATAGTCAGACCCTAGGAAATGATATGTTAATGAATACACCCAGGGCACACACGGTTGAAGAGGTTAATACTGATGAGGATCAAAAGGAGGAGTCAAATGGATTAAACGAAGACATTCTGGACAATCCATGTAATGATGCTATTGCCAATACTTTAAATGAAGAGGAAACACTGCTGGACCAGTCTTTTAAAAATGTGCAACAGCAACTTGATGCTACATCCAGAAATATTACTGAAGCTAGATAAGTTTCCATTAAGAGAAAATGTATCTGTTAAGTCATCGTCCTGCAAGCTTGGCGTTACTATGTATTTTTTCTTCTTGGAGTGAAAATCCTTAGATAGTAAAACTGTTATAGATTATTGTTTAAAATCTGATAATCTGGTATTTATTTATAATTATGCTTGTCACTTTAGTTAAATCTATTTGTTCTCTTTAGTGTTTGTTTTTATATAGGTATTTCTTCATAAAATGATTAGGAGGTAATAAGCAGTTTCTGCTGCTGGTCTGTCATTGAATGCCTTGTTTTCACTAAGTTGGGAGGTTTTGTTTCTGTTTTTtactgctccttgcaaagcagggctaatccatggacagtgtgcccagagtagTCTAGTTGAAGTTttttgttttgttttgttttgttttttttgACacagagtctcactctgttggccaggctggagtgcagtggcacagtcttggctcactgcaacctctgcctcctgggctcaagcaattctcctgccttagcctcccgagtagctgggactacaggcgtgtgccaccacgcttggctaatttttgtacttttagtagagatgaggtttcaccatgttggccaggctggtctcaaactcctaacctcaggtaatccgcccccctcggcctcccaaagtgctgggattacaggtgtgagccaccgcgcccagccTGGGTGAAGTTTTGAGATGTACATATATACTGAATATTAATGTCAATTTTTTAAAAGAAGTAAAAATTATCTTAAAAACTA

Publications

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