Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name MTFR1P1
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr8). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:66359593-66361787  UCSC
Coordinates (T2T) chrX:64787364-64789558  UCSC
Coordinates (hg19) chrX:65579435-65581629  UCSC
Strand -
Parental Sequence NM_014637.4
Parental seq. overlap 1825 bp
Parental seq. overlap (%) 66.4%
Genomic Region Intergenic
Retrocopy Summary MTFR1P1, located on chrX:66359593-66361787, is a retrocopy of the parental gene MTFR1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name MTFR1
Full Name mitochondrial fission regulator 1
Also known as CHPPR|FAM54A2
Coordinate chr8:65643873-65771252
Strand +
Gene summary This gene encodes a mitochondrial protein that is characterized by a poly-proline rich region. A chicken homolog of this protein promotes mitochondrial fission and the mouse homolog protects cells from oxidative stress. A related pseudogene of this gene is found on chromosome X. [provided by RefSeq, Mar 2009]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes MTFR1P1
Bonobo Pan paniscus MTFR1P1
Gorilla Gorilla gorilla MTFR1P1
Orangutan Pongo abelii MTFR1P1
Crab-eating macaque Macaca fascicularis MTFR1P1
Rhesus Macaca mulatta MTFR1P1
Baboon Papio anubis MTFR1P1
Golden snub-nosed monkey Rhinopithecus roxellana MTFR1P1
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>MTFR1P1
ACTTTGCATCTAAATGCTTCGCTGGGTTAATAGCCTAATTAGGATGATTTTCCAACAAGTTGGAGTAAGCATGCAATTGGTATTTTGGCCTGGGAAGCCATATGGTTTGTCTCTAAGTATCATGAAGAAAATTGTTACTATTAATAATTTATCCGTGATCTGGTGTCCAAGCTTACCTGCCATGCAACAGAATCGTGTCCCAACCACCCAGGAGAGGATGCAGTGTTGTCTTTTGTGGCTGTCGAATGGGTAGCCAAAGGAGAGTGTTCAACAAGACTAAGAACAGAGACCAGGCCAAGGCCATCCTTTCAAGATGACCTTTTCTTTGAGAAGGCCCCAAGCAGACAGATTTCCTTACCAGACTTGTCTCAAGAGGAGCCTCAGCTGAAGACTCCAGCTTGGTAAATGAGGAAGCACTGCAGAAGATTTGTGCTCTTGAAAATGAACTTGCTGCTCTCAGAGCTCAGATAACCAAAATTGTGACTCAGCAATAGCAGGAAAATCTAATTTCAAGTGACTTAGATTTTACCACATCTGTTACCACACCACCATCCCCTCCACCTCTCCACCAGTCTTGCCCGCCCTCTCCACTGGGACTCCACCAAAGTATATTTGATATTGATCTGATTAGAGAGTGAGGAGGGAGAAAAGCCAATTCTGGAAAGACGTTGGTTAAGAACAATCCAAAAAAAGCTGACATGCCAAAAATGCTAGAGACTCTTAAAGACATGATCAGTGTAAAACTTTAGTCAGTAAAAACCTCAGAGCAAGATGTACAGCCCAAGCCAGTGGATGCTGCTGGACTTGCTCCCCTCATAGCAGAGGCTCTGAAAAAGAAAAATTTGCTTATCGGAATCAAAGTAGTATACCAATAGGCTTATTGGTATACCCAGGATGAAGTTGAAAAAGGAGTTCCAAAGTCTGAATCAGAGGCCACCTCAGATACAGAGTTGTCTGCACTACACATGTTGAAGTCAACAGGAAAAATGAAGGCTTTAATGGAAAATATAACAAACTCCTAATAGACAATGAACTGCAAAAGACTATCCTGGTTCAACTATTGGTTTGTGAGGGGTAACTTTGACTAGTATAAATCAATACTATTTAGCAAATACCTGATTTTAGTATTCAGTGGTCTCCTTTTCAGTCTAATTAGAGGATTAAACAATAACAAAAGCACAATAAGTTTGGTTTTGCTTTTATGAGATGTTCAGTTTTGGCATTCTCCTCAGCATATGTGTATTCAGATGTGTTTCTAATGTGTAGCCAGGGTGTTCAGATTTCCCGTCTTGAAAACAATTGTATAGATTTTAGAACACAGAGAGGACACTTGTGGATGTTACTGCACATTTTTATTATTAACACTAGTTTATCTGCATAAATGTTTATATGCATGTTTTTTGACAGTTTATGTAAAATTAGTAATGAATGATGGCAATGGCTTTAACCTATAATTGTTACCATTATAAGGTATGGTTATTTTTGTTTGTTTTGAATAATCACTTAGTATTCAATGGTGGAACAGCTAGTATAACATAAGTTGTTGGCATGAAATACTTGAGATTGGAAACTTCTTGCCTTAAACAGAATTTATATACTAGATCCTCTCTCACATTTTCTTGGAGCTGGGATTTGAGTAGAAACCAGGTGATAGTCCCCGCTGAAATTCCATAATGCTTTCCATTAAAGGGAAGTTCAGAACTAGGAAAGTTGTTTTTACCTCATTGTCATCCAGGACAGAAGAAGAAAATGTAGTTTTCAAATAGTAACAAATCAAATTAGTGATTTAAATATCCTTTTAAGTAAAACCCAGAATGTATCATCTTTTCTTTCAGTTTAATAAATAGCATTATAAATATTATTTTGCTAAGTTAATACTTCTGGAAATATCAGAATAGAGTTTTAAAATCTTTAATATTGGTCAAAATATTAACTTTATAGTGAAACATTAAGCAAGCAAATTTTCTATAAATTATTTATCATTGGCCAGAATGCTATTTTGTTTAATTGTATTATGCAATATAAACCATAGGTGTTATTAGAAAGTGGAGAATTGCTTTTCTTATCTAGAGCTTTTAACCACTTGATGTAAATGATTATTTTTTAAATATCTTATAAATCTTAATGATTTTTCTATTTCTTATAAACTCAGCTACAGTTAATGCCAGAATATCCTACCATGAGTAAATATTTGT
>NM_014637.4
AAGCTAGAAGCCTGAGGAGCCGGAGAGGGTGCTGGCTGCCGCGCGGCCGAGTGTGTTTTATGGACCATGTGCTGCTATGTATGCCTGAAGAAGTACTTGAAATGCAAATTTGGGGAGACTTTGCCATATAAATGCTTGGCTGGATTAAGCGCCTAATTAGGATGGTTTTTCAACAAGTTGGAGTAAGCATGCAATCGGTACTTTGGTCTAGGAAGCCATATGGTTCGTCTCGAAGTATCGTAAGGAAAATTGGTACTAATTTGTCTCTGATTCAGTGTCCAAGAGTTCAGTTTCAGATTAACAGCCATGCAACAGAATGGAGTCCCAGCCACCCAGGAGAGGATGCAGTGGCGTCTTTTGCTGATGTTGGATGGGTAGCCAAAGAAGAAGGAGAGTGTTCAGCAAGACTAAGGACAGAGGTCAGATCAAGGCCACCCCTTCAGGATGACCTTCTTTTCTTTGAGAAGGCCCCAAGCAGACAGATTTCCTTACCAGACTTGTCTCAAGAAGAGCCTCAGCTGAAGACCCCAGCGCTGGCAAATGAGGAAGCACTGCAGAAGATTTGCGCTCTCGAAAATGAACTTGCTGCTCTCAGAGCTCAGATTGCCAAAATTGTGACCCAGCAGGAGCAGCAAAATCTCACTGCAGGTGACTTAGATTCTACCACATTTGGTACCATAccaccacaccctccacctcccccaccgcccctgcctccccctGCACTGGGGCTCCACCAAAGTACATCTGCTGTTGATCTGATTAAAGAACGAAGAGAGAAAAGAGCCAATGCTGGAAAGACTTTGGTTAAGAACAATCCAAAGAAACCTGAAATGCCAAATATGCTAGAGATCCTTAAAGAGATGAACAGTGTAAAACTTCGGTCAGTGAAGAGGTCAGAGCAAGATGTGAAGCCCAAGCCAGTGGATGCTACTGACCCTGCTGCCCTCATAGCAGAGGCTCTGAAAAAGAAATTTGCTTATCGGTATCGAAGTGATAGCCAAGATGAAGTTGAAAAAGGAATTCCAAAGTCTGAATCAGAGGCCACCTCAGAGAGAGTGTTGTTTGGGCCACACATGTTGAAGCCAACAGGAAAAATGAAGGCTTTAATTGAAAATGTATCAGACTCCTAATAGACAATGAGCTGCGAAAAGACTCCTGGTTCCCCTGTTGATTTGTGAGGGCCAAGTTTGCTAGTAGAAATCGACACTGTTTAGTAAATACCTCTTTAGTATTCAGTGGTCTTCTTTTCAGGCTAATTAGTGGATTAAGCAATAATGAAAGCACTAAGTTTGGTTTTGCTTTTGTGAGATGGTCAGCTTTGGTGCTCTCCACAACATGTGTGTTCTGACATGTTTCTAATATGTGGCCAGGGCGTTCAGATTTCCAGTTTTGAAAACAATTGTATAGATTTCACAACACAAAAAGGACATTTGTGGATGTTACTGCACATTTTAAATTCTTAACACTAATTTATCTGTATAAGTGTTTTATATGCATATTTTTGGACATAAACAGTTTATGTAAAATTAGTAATGAATGATGGCAACGAGGGCACTGTTATCTTCGTTTGTTTTCAATGATCATTTAGCATTCAATGATGGAACAGCTGGTATAACATAAGTTGTTGGCATGAAATATTTGAGATTGGAAACTTCTTGCCTTGAACAGAACTTATATCTTAGATTCTCTCTCACATTTTCTTGGAGCTGGGGTTTGAATAGGAACCAGATGATGTTCACTGCTGAAATTCCATAATGCTTCCCATTGAAGGGAAGTTGAGAACCAGGAAAGCTGCTTTCACGTCATTGCCATCCAGTACTGACAGGGAAGAAAGATGTAGTTTTCCAGTAGTGATGAATCAAATTATTGAATTAAATTTCTTCTTAAGAAGTAAAAACTCAGAATGTACCATCTTGTTTCCTTTCAGTTTATTAAATGGCATCATAAAGATGACTTTGCTAAGTTAATAGAGTTAAAAATTTTTTTAATATAAGCCAAAATATTAACTTTAATGAAACATTGACTTGGCAAATGAATTTCCTATAAATTATCATTGGTCAGAATGCTGTTTTGTTTAATAATATTACGCAACATAAACCATAGGTGTTATTAGAAGTGGAGAACTGCCTTTTTCATCTGGGGCTTTTAAGGACTTGCTATAAATGATTATTTTTTAAATGCTTTATAAATCTTCATGGTTTTTCTATTTCTGATACACTCAGCTATAGTTAATACCAGAGTATCCTACCAGGAGTAATATTTGGAATATTTAAATCTAGTAAAAGAAGAAAGTTGTACTTCCTGGCTGGGAGTATTAGGAGATGGGAGTAGAGATTCACTTTTAAGTTCTTGAAAATATATGCATTCTCCTAAATATTAACAAAAATGATTTGGGGAAATGACATGGCTTGATTGTTCTGTTTAAATTTGTACTGTGGCTTATGTTACACATGTTCATGTTCACCTCTCATTCACCTGTTTTATATGGTTTAAAATTCTCTTTAACAAAATTCAGAAAATTCACCTGAAACGTATTTTGACCTAAAAGAAACATATTTTTGTATCAGTATTGAATTTTGGACAGTGCCCCCATATAAGGAAGTTACTGTTTTAAAATAAAGCAAACTAACTGTTTTATTTTCCTTGGA

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