Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name BCL2L2-PABPN1P1
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr14). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:67533478-67533779  UCSC
Coordinates (T2T) chrX:65963309-65963610  UCSC
Coordinates (hg19) chrX:66753320-66753621  UCSC
Strand +
Parental Sequence NM_001387345.1
Parental seq. overlap 263 bp
Parental seq. overlap (%) 8.6%
Genomic Region Intergenic
Retrocopy Summary BCL2L2-PABPN1P1, located on chrX:67533478-67533779, is a retrocopy of the parental gene BCL2L2-PABPN1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name BCL2L2-PABPN1
Full Name BCL2L2-PABPN1 readthrough
Also known as -
Coordinate chr14:23306833-23326163
Strand +
Gene summary This locus represents naturally occurring read-through transcription between the neighboring BCL2L2 (BCL2-like 2) and PABPN1 (poly(A) binding protein, nuclear 1) genes on chromosome 14. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Dec 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes LOC452797P2
Bonobo Pan paniscus LOC100981014P2
Gorilla Gorilla gorilla LOC101134783P2
Orangutan Pongo abelii LOC100442963P2
Gibbon Nomascus leucogenys LOC100598768P2
Crab-eating macaque Macaca fascicularis LOC101867156P1
Rhesus Macaca mulatta LOC713572P2
Golden snub-nosed monkey Rhinopithecus roxellana LOC104674154P2
Marmoset Callithrix jacchus LOC100396934P6
Green monkey Chlorocebus sabaeus Without Homology
Baboon Papio anubis Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>BCL2L2-PABPN1P1
AGAGGAAGAAGCTGAAAAGCTTCAGGAGCTACAGAATGAAGTAGACAAGCAGATGAATATAAGTCTACCTCTAGACAATGCTAGCCCAGTGATCATCCATTGAGGAGAAGATGAAGGCTGATGTCGCTTCCATCTATGTTGGCAATGTGAACTATGATGCAACAGCAGAAGTGCTGGAAGCACACTTTTATGGTTGTGGTTCAGTCAACAGCGTTACCATACTCTTTGGCTAATTAGAGGCCATTCCAAGGGGTTTGTATATACAGAGTTCTGAAACAAAGAGTCAGAAAGGACTTCCTTGG
>NM_001387345.1
ctctccctccctcccAGCTCCTGCACCAGGAAACGGCCCGGATCCCGGCAGCGGCCTGACCCGTGAGATCCCTAACCTGGCAGGCGGGCGGGGTTGGAGACTGGCTGAGGTGGGGGGCTCCACGCTGGCCAGGAGGATGAAAGGCCCCAGCTGGGGGCTCCTTGCCACCAGTGCTGTGTCTTAAGAGCTGCCATCCCGGCTGGCCGCCCGGATGGCGACCCCAGCCTCGGCCCCAGACACACGGGCTCTGGTGGCAGACTTTGTAGGTTATAAGCTGAGGCAGAAGGGTTATGTCTGTGGAGCTGGCCCCGGGGAGGGCCCAGCAGCTGACCCGCTGCACCAAGCCATGCGGGCAGCTGGAGATGAGTTCGAGACCCGCTTCCGGCGCACCTTCTCTGATCTGGCGGCTCAGCTGCATGTGACCCCAGGCTCAGCCCAACAACGCTTCACCCAGGTCTCCGATGAACTTTTTCAAGGGGGCCCCAACTGGGGCCGCCTTGTAGCCTTCTTTGTCTTTGGGGCTGCACTGTGTGCTGAGAGTGTCAACAAGGAGATGGAACCACTGGTGGGACAAGTGCAGGAGTGGATGGTGGCCTACCTGGAGACGCAGCTGGCTGACTGGATCCACAGCAGTGGGGGCTGGGAGCTGGAAGCTATCAAAGCTCGAGTCAGGGAGATGGAGGAAGAAGCTGAGAAGCTAAAGGAGCTACAGAACGAGGTAGAGAAGCAGATGAATATGAGTCCACCTCCAGGCAATGCTGGCCCGGTGATCATGTCCATTGAGGAGAAGATGGAGGCTGATGCCCGTTCCATCTATGTTGGCAATGTGGACTATGGTGCAACAGCAGAAGAGCTGGAAGCTCACTTTCATGGCTGTGGTTCAGTCAACCGTGTTACCATACTGTGTGACAAATTTAGTGGCCATCCCAAAGGGTTTGCGTATATAGAGTTCTCAGACAAAGAGTCAGTGAGGACTTCCTTGGCCTTAGATGAGTCCCTATTTAGAGGAAGGCAAATCAAGGTGATCCCAAAACGAACCAACAGACCAGGCATCAGCACAACAGACCGGGGTTTTCCACGAGCCCGCTACCGCGCCCGGACCACCAACTACAACAGCTCCCGCTCTCGATTCTACAGTGGTTTTAACAGCAGGCCCCGGGGTCGCGTCTACAGGTCAGGATAGATGGGCTGCTCCTCTTTCCCCCGCCTCCCGTGAGCCCCGTATGCTTCCTCCTCTCTGGTCTGAGGAACCTCCCTCCCCCCACCCCTCCCCGTGGTCTTCAGGAACTTTGTCTCCTGCCTGTGCAGGTTGAGGAAGGTAGTTGCAGGCCAGGCCAGAAGGCCAGCCTCATCATCTTTTCTGCAGTAGAAATTGGTGATAAGGGCTGCATCCCTCCCTTGGTTCAAAGAGGCTTCCACCCCCAGCCTTTTTTTTCTTGGGAGTTGGTGGCATTTGAAGGTGTTTGCGGACAAAACTGGGAGGAACAGGGCCTCCAGGCAGTGAAAGCACTGCTTGGACATTTGTTACTTTTTTCGGAGTTAGGGAGGGATTGAAGACTGAACCTCCCTTGGAAGAATACCAGAGGCTAGCTAGTTGATCCTCCCCAACAGCCTTGTGGGAGGATTTTGAGATACTTATTCTTTATTTGAGCCAGTCTTGCAAGGTTAACTTCTCACTGGGCCTAGTGTGGTGCCCAGGTTTTTGCCTTGCTTCACTTCTGTCTCTACATTTAAATAGACGGGTTAGGCATATAAACCTTGGCTTTTCATAAGCTCTACCTGCCTATCCCCAGGAGTTAGGGAGGATCTATTTGTGATGGCCTAGGGTTTAAGAGCTGTGGAGGACTGAAAACTGGATAAAAAGGGGGTCCTTTTCCTTGCCCCTGTCTCTCACTCAGATGCGCTTCTTTTTCGCCACTGTTTGGCAGTTTTCTGTTAAGCCCCCCTCCCCCTGCCCCAGTTCTCCAGGTGCGTTACTATTTCTGGGATCATGGGGTCAGTTTTAGGACACTTGAACACTTCTTTTCCCCCCTTCCCTTCACAGTAACTGGGGCAGGGGCCTACGGGGAGGGGCTTGTACTGAACTATCTAGTGATCACGTTAACACCTAACTCTCCTTCTTTCTTCCAGGGGCCGGGCTAGAGCGACATCATGGTATTCCCCTTACTAAAAAAAGTGTGTATTaggaggagagagaggaaaaaaagaggaaagaaggaaaaaaaaaagaattaaaaaaaaaaaaaagaaaaaCAGAAGATGACCTTGATGGAAAAAAAATATTTTTTAAAAAAAAGATATACTGTGGAAGGGGGGAGAATCCCATAACTAACTGCTGAGGAGGGACCTGCTTTGGGGAGTAGGGGAAGGCCCAGGGAGTGGGGCAGGGGGCTGCTTATTCACTCTGGGGATTCGCCATGGACACGTCTCAACTGCGCAAGCTGCTGCCCATGTTTCCCTGCCCCACTTCACCCCCTTGGGGGCTGCTCAAGGGTAGGTGGGCGTGGGTGGTAGGAGGTTTTTTTTTTTACCCAGGGCTCTGGAAGGACACCAAACTGTTCTGCTTGTTACCTTCCCTCCGTCTTCTCCTCGCCTTTCACAGTCCCCTCCTGCCTGCTCCTGTCCAGCCAGGTCTACCACCCACCCCACCCCTCTTCTCCGGCTCCCTGCCCCTCCAGATTGCCTGGTGATCTATTTTGTTTCCTTTTGTGTTTCTTTTTCTGTTTTGAGTGTCTTTCTTTGCAGGTTTCTGTAGCCGGAAGATCTCCGTTCCGCTCCCAGCGGCTCCAGTGTAAATTCCCCTTCCCCCTGGGGAAATGCACTACCTTGTTTTGGGGGGTTTAGGGGTGtttttgtttttcagttgttttgtttttttgttttttttttttttCCTTTGCCTTTTTTCCCTTTTATTTGGAgggaatgggaggaagtgggaacagggaggtgggaggtggATTTTGTTTATTTTTTTAGCTCATTTCCAGGGGTGGGAATTTTTTTTTAATATGTGTCATGAATAAAGTTGTTTTTGAAAATAAAAA

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