Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name BMI1P1
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr10). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:67791428-67792876  UCSC
Coordinates (T2T) chrX:66223415-66224864  UCSC
Coordinates (hg19) chrX:67011270-67012718  UCSC
Strand -
Parental Sequence NM_005180.9
Parental seq. overlap 914 bp
Parental seq. overlap (%) 25.4%
Genomic Region Intergenic
Retrocopy Summary BMI1P1, located on chrX:67791428-67792876, is a retrocopy of the parental gene COMMD3-BMI1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name COMMD3-BMI1
Full Name COMMD3-BMI1 readthrough
Also known as BMI1|PCGF4|RNF51
Coordinate chr10:22316388-22331484
Strand +
Gene summary This locus represents naturally occurring read-through transcription between the neighboring COMM domain-containing protein 3 and polycomb complex protein BMI-1 genes on chromosome 10. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Feb 2011]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes BMI1P3
Bonobo Pan paniscus BMI1P1
Gorilla Gorilla gorilla BMI1P1
Gibbon Nomascus leucogenys BMI1P1
Green monkey Chlorocebus sabaeus BMI1P1
Crab-eating macaque Macaca fascicularis BMI1P1
Rhesus Macaca mulatta BMI1P1
Baboon Papio anubis BMI1P1
Golden snub-nosed monkey Rhinopithecus roxellana BMI1P1
Marmoset Callithrix jacchus BMI1P2
Mouse lemur Microcebus murinus LOC105872911P2
Sloth Choloepus didactylus BMI1P7
Orangutan Pongo abelii Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>BMI1P1
AAGCTCCTAATTTATATAGGTATGTCTATGCCATTACAGCTTTACAAACACTAATACACATGACTGTGGTCAAATTTGCTTTCTTTTGTAGTTACATTGAATTTGACTATAAAAGATGGACCAAGTGTGACATTCATATATACATTACTTGGAAAGAAAGATTGTCTTAAAAAGAACTGGTTTTTCAAAATCACTGAGCTAAATCCCCACTTAATGTGTGTGCTTTGTGGAGGATACTTAATTGATGCCAGAACCATAATAGAATATCTGCATTCCTTCTGTGAAACCTGTATTTCGTGTTACCTATAGATCAGCAAATATTGTCCTTTAATGTCCAAGTTCACAAAACCATTATGCTCTGAATATAACATCAGATAAAAATCCTCAATCTATTGTATACAATTACTTCCAGGCCTTTTCAGAAATAAAATGAGAAGGGATCTTTATGCATCTCTTTATTCAGCTGTTGCTGCCAATGGCGCTAATGAAAATAGAGAAGTTGCAGATGAAGATAAGAGAATTATAACTGATGGCGAAACAATAAGCTTATCCATTGGATTTTTTTTTTTGACCAGAACAGAAAGTAAACAAAGACAAAGAGAAGTTTAAGGAGGAGGTGAATGATAAAAGTTATTTACAATGCTCAGCCAGAATGACTGTGATGAACCTAAGGAACATATCTTATACTTCCCAATTGATGTCATGTATGAAGAGGAATCTTTAAAGGATAAATATACATTAATGGATATTACTTACATTTATATGTGGATAAGAAATGGACTTCTTCCTTTAAAGTACGGTGTTTGACCTATTAGTAAAAGAATGAAGCTTAGTTGCTGGAGAGATGAACTGACAAAAATGCTGGAGAACTGGAATGTGACTTTGGAATTAACAAGGCCAATGGCCTAGTAGGAGTTATTTCCTCTAGCTCTTCTTGTTTGCCTAGCTGCACTACTCCAATCCAGTCTCCTCATCTTCACTTTCCTCACATGCCCAGTATTATGAATGCCACCAGGAACAGTCCCACTGGTAACTATGAACCTTTCTCTGCCAACAGACCTAAAAAATCATCAGCAAATGGGTTATTAGAAACTTCATTCTTAGGTTGATAACTGAGACTGTTAAGGAAAAAAAAATCCAGCTCCTAAt
>NM_005180.9
AGTTTCCACTCTGCCTTCAGCGGTGCATTTTTTTCCAccctcccctccccctcctcccctccccccgctcgcacgcacacacacggcgccccccgcccgcccgccTCCCCCACAGCAACTATGAAATAATCGTAGTATGAGAGGCAGAGATCGGGGCGAGACAATGGGGATGTGGGCGCGGGAGCCCCGTTCCGGCTTAGCAGCACCTCCCAGCCCCGCAGAATAAAACCGATCGCGCCCCCTCCGCGCGCGCCCTCCCCCgagtgcggagcgggaggaggcggcggcggccgaggaggaggaggaggaggccccggaggaggaggcgttggaggtcgaggcggaggcggaggaggaggaggccgaggcgccggaggaggccgaggcgccggagcaggaggaggccggccggaggcggCATGAGACGAGCGTGGCGGCCGCGGCTGCTCGGGGCCGCGCTGGTTGCCCATTGACAGCGGCGTCTGCAGCTCGCTTCAAGATGGCCGCTTGGCTCGCATTCATTTTCTGCTGAACGACTTTTAACTTTCATTGTCTTTTCCGCCCGCTTCGATCGCCTCGCGCCGGCTGCTCTTTCCGGGATTTTTTATCAAGCAGAAATGCATCGAACAACGAGAATCAAGATCACTGAGCTAAATCCCCACCTGATGTGTGTGCTTTGTGGAGGGTACTTCATTGATGCCACAACCATAATAGAATGTCTACATTCCTTCTGTAAAACGTGTATTGTTCGTTACCTGGAGACCAGCAAGTATTGTCCTATTTGTGATGTCCAAGTTCACAAGACCAGACCACTACTGAATATAAGGTCAGATAAAACTCTCCAAGATATTGTATACAAATTAGTTCCAGGGCTTTTCAAAAATGAAATGAAGAGAAGAAGGGATTTTTATGCAGCTCATCCTTCTGCTGATGCTGCCAATGGCTCTAATGAAGATAGAGGAGAGGTTGCAGATGAAGATAAGAGAATTATAACTGATGATGAGATAATAAGCTTATCCATTGAATTCTTTGACCAGAACAGATTGGATCGGAAAGTAAACAAAGACAAAGAGAAATCTAAGGAGGAGGTGAATGATAAAAGATACTTACGATGCCCAGCAGCAATGACTGTGATGCACTTAAGAAAGTTTCTCAGAAGTAAAATGGACATACCTAATACTTTCCAGATTGATGTCATGTATGAGGAGGAACCTTTAAAGGATTATTATACACTAATGGATATTGCCTACATTTATACCTGGAGAAGGAATGGTCCACTTCCATTGAAATACAGAGTTCGACCTACTTGTAAAAGAATGAAGATCAGTCACCAGAGAGATGGACTGACAAATGCTGGAGAACTGGAAAGTGACTCTGGGAGTGACAAGGCCAACAGCCCAGCAGGAGGTATTCCCTCCACCTCTTCTTGTTTGCCTAGCCCCAGTACTCCAGTGCAGTCTCCTCATCCACAGTTTCCTCACATTTCCAGTACTATGAATGGAACCAGCAACAGCCCCAGCGGTAACCACCAATCTTCTTTTGCCAATAGACCTCGAAAATCATCAGTAAATGGGTCATCAGCAACTTCTTCTGGTTGATACCTGAGACTGTTAAGGAAAAAAATTTTAAACCCCTGATTTATATAGATATCTTCATGCCATTACAGCTTTCTAGATGCTAATACATGTGACTATCGTCCAATTTGCTTTCTTTTGTAGTGACATTAAATTTGGCTATAAAAGATGGACTACATGTGATACTCCTATGGACGTTAATTGAAAAGAAAGATTGTTGTTATAAAGAATTGGTTTCTTGGAAAGCAGGCAAGACTTTTTCTCTGTGTTAGGAAAGATGGGAAATGGTTTCTGTAACCATTGTTTGGATTTGGAAGTACTCTGCAGTGGACATAAGCATTGGGCCATAGTTTGTTAATCTCAACTAACGCCTACATTACATTCTCCTTGATCGTTCTTGTTATTACGCTGTTTTGTGAACCTGTAGAAAACAAGTGCTTTTTATCTTGAAATTCAACCAACGGAAAGAATATGCATAGAATAATGCATTCTATGTAGCCATGTCACTGTGAATAACGATTTCTTGCATATTTAGCCATTTTGATTCCTGTTTGATTTATACTTCTCTGTTGCTACGCAAAACCGATCAAAGAAAAGTGAACTTCAGTTTTACAATCTGTATGCCTAAAAGCGGGTACTACCGTTTATTTTACTGACTTGTTTAAATGATTCGCTTTTGTAAGAATCAGATGGCATTATGCTTGTTGTACAATGCCATATTGGTATATGACATAACAGGAAACAGTATTGTATGATATATTTATAAATGCTATAAAGAAATATTGTGTTTCATGCATTCAGAAATGATTGTTAAAATTCTCCCAACTGGTTCGACCTTTGCAGATACCCATAACCTATGTTGAGCCTTGCTTACCAGCAAAGAATATTTTTAATGTGGATATCTAATTCTAAAGTCTGTTCCATTAGAAGCAATTGGCACATCTTTCTATACTTTATATACTTTTCTCCAGTAATACATGTTTACTTTAAAGATTGTTGCAGTGAAGAAAAACCTTTAACTGAGAAATATGGAAACCGTCTTAATTTTCCATTGGCTATGATGGAATTAATATTGTATTTTAAAAATGCATATTGATCACTATAATTCTAAAACAATTTTTTAAATAAACCAGCAGGTTGCTAAAAGAAGGCATTTTATCTAAAGTTATTTTAATAGGTGGTATAGCAGTAATTTTAAATTTAAGAGTTGCTTTTACAGTTAACAATGGAATATGCCTTCTCTGCTATGTCTGAAAATAGAAGCTATTTATTATGAGCTTCTACAGGTATTTTTAAATAGAGCAAGCATGTTGAATTTAAAATATGAATAACCCCACCCAACAATTTTCAGTTTATTTTTTGCTTTGGTCGAACTTGGTGTGTGTTCATCACCCATCAGTTATTTGTGAGGGTGTTTATTCTATATGAATATTGTTTCATGTTTGTATGGGAAAATTGTAGCTAAACATTTCATTGTCCCCAGTCTGCAAAAGAAGCACAATTCTATTGCTTTGTCTTGCTTATAGTCATTAAATCATTACTTTTACATATATTGCTGTTACTTCTGCTTTCTTTAAAAATATAGTAAAGGATGTTTTATGAAGTCACAAGATACATATATTTTTATTTTGACCTAAATTTGTACAGTCCCattgtaagtgttgtttctaattatagatgtaaaatgaaatttcatttgtaattggaaAAAATCCAATAAAAAGGATATTCATTTAGAAAATAGCTAAGATCTTTAATAAAAATTTGATATGAAAAGCACAATGTGCAGAAGTTATGGAAAACCTATAGAGGATTACAACAGGTAAACGTTAAAGAGAATACATTGCTGACTTATAGTGATGTGGCTAAGAAGTACATGCTTTGTTGTAAAATTGCTTGAAAGCCCATTGAAAGATGTATCTGTTTATTTACAGTCTTTGAAGTAAAAGTTACCAATGTTTGCCAA

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