Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name AARSD1P1
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr17). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:74069257-74070769  UCSC
Coordinates (T2T) chrX:72502802-72504313  UCSC
Coordinates (hg19) chrX:73289092-73290604  UCSC
Strand +
Parental Sequence NM_001261434.2
Parental seq. overlap 992 bp
Parental seq. overlap (%) 73.4%
Genomic Region Intergenic
Retrocopy Summary AARSD1P1, located on chrX:74069257-74070769, is a retrocopy of the parental gene AARSD1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name AARSD1
Full Name alanyl-tRNA synthetase domain containing 1
Also known as AlaXp
Coordinate chr17:42950526-42964454
Strand -
Gene summary Predicted to enable Ser-tRNA(Ala) hydrolase activity. Predicted to be involved in regulation of translational fidelity. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes AARSD1P2
Bonobo Pan paniscus AARSD1P2
Orangutan Pongo abelii AARSD1P2
Gibbon Nomascus leucogenys AARSD1P2
Green monkey Chlorocebus sabaeus LOC103243378P2
Baboon Papio anubis LOC101016032P2
Golden snub-nosed monkey Rhinopithecus roxellana LOC104679976P1
Marmoset Callithrix jacchus AARSD1P1
Gorilla Gorilla gorilla Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>AARSD1P1
GGAGTCCACCACCACCATAATCTCCTGTGATCCCACGGAGCTGCAGTCAGAAGGGAGCAATGACAAGAAATAAGTGCTGAGCAGTTGTCATATGGTGCTGGAAGACATGCTACTTTTCCCTGAGGGCGGAAGACAGCCTGATGACGGTGGTACAATCAATGACATCTCTGTGCTGGGAGTGACCTGCTTGGGGGCCCAGGCTGATCATTTCACACAGACACCCCTGGATCCTGGAAGCCAAGTCCTGGTCTGGGTAGACTGGGAGTGGAGGTTTGACCACATGCAGCAGCATTAAAGGCAGCATCTCATCACAGCAGTTGCTGATTATCTGTTTGAGTTAAAGACAACATCATGGGAGTTAGGGAAATTTCGGAGTGTGATGCTGGAAAGCCCCTCTGTGAATGCAGAGAAAATAACCGCCACTGAAAAGAGTGTCAATAAAAATATCAGAGATCAGCTGCTCAACAAAGTATGAGAACTGAGCCTGAATGATCCTGAGGCGGAGCAGGTGAGAGGCTGGGGCCTGCCAGATGATCATGCTGGGCCCATTGGAATTGTTACCATCAAGGGTGTTGATTCCAACATGTGCTGTGGGATCCCCATGAGCAATCTCCGTGACTTTCCAGTCATTAAGATTAGGCACCGAGAAGAGGAAAAGGAATAAAATCAAACTGATATTTCTGGCTGGGAACCAGATGCTGAAATGGATGAAGAGAAGTCATGAAACTGAAAGAGCACTGAATCACTCTGCTTAAGTGTGGAGCAGAGGATCACATGGAAGCAGTGAAAAAGCTCCAGAATGTAaAAAGAAAAAGTTCCAGAACTCCACCAAGCTCCTGCAGAAGAACAACCTGAATCTGCTCAGAGACTCAGCTGTGCACATTGCCCATAGCCTCAGGACCAACCCAGACTCGGGGGATGTGGTCATATTACACAGGAAGGAGGGTGATTCATAGTTCATGAATATTGTTGCCAATGAGATTGGGTCAGAGGATTCCTTCCTGTTCTTAAACATGGGTGATGAGAAAGGTGCTGGGCTCTTTTTACTGGCAGGGCCACCTGAGACCATGGAGACCCTGGGGCCCAGGGTGGATGAGGTCCTAGAAGGCAAAGGAGCAGGGAAGAAAGGCTGCTTTCAGGGCAAAGTCACCAACATGAGCC
>NM_001261434.2
ACACGCCTGCAGGTATGGCGTTCTGGTGTCAGCGTGACAGTTATGCCCGAGAGTTCACCACCACCGTGGTCTCCTGCTGTCCCGCGGAGCTGCAGACTGAAGGGAGCAACGGCAAGAAAGAAGTGCTGAGCGGTTTCCAAGTGGTGCTGGAAGACACAGTGCTTTTCCCTGAGGGCGGGGGACAGCCTGATGACCGTGGTACAATCAATGACATCTCTGTGCTGAGAGTGACTCGCCGTGGGGAACAGGCTGATCATTTCACCCAGACACCCCTGGATCCAGGAAGCCAGGTTCTGGTCCGGGTAGATTGGGAGCGGAGGTTTGACCACATGCAGCAGCATTCAGGGCAGCATCTCATCACGGCAGTTGCTGACCATCTATTTAAGCTGAAGACAACATCATGGGAGTTAGGGAGATTTCGGAGTGCGATTGAGCTGGACACCCCCTCTATGACTGCAGAGCAAGTAGCTGCCATTGAGCAGAGCGTCAATGAAAAAATCAGAGATCGGCTGCCTGTGAATGTCCGAGAACTGAGCCTGGATGATCCTGAGGTGGAGCAGGTGAGTGGCCGGGGTTTGCCTGATGATCATGCTGGGCCCATTCGGGTTGTTAACATCGAGGGCGTTGATTCCAACATGTGCTGTGGGACCCATGTGAGCAATCTCAGTGACCTTCAGGTCATTAAGATTCTGGGCACTGAGAAGGGGAAAAAGAACAGAACCAACCTGATATTTCTGTCTGGGAACCGGGTGCTGAAGTGGATGGAGAGAAGTCATGGAACTGAAAAAGCACTGACTGCTCTGCTTAAGTGTGGAGCAGAGGATCATGTGGAAGCAGTGAAAAAGCTCCAGAACTCCACCAAGATCCTGCAGAAGAATAACCTGAATCTGCTCAGAGACCTGGCTGTGCACATTGCCCATAGCCTCAGGAACAGTCCAGACTGGGGAGGTGTGGTCATATTACACAGGAAGGAGGGTGATTCAGAGTTCATGAATATCATTGCCAATGAGATTGGGTCAGAGGAGACCCTCCTGTTCTTAACTGTGGGCGATGAGAAAGGTGGTGGACTCTTCTTACTGGCAGGGCCACCTGCGTCTGTGGAGACCCTGGGGCCCAGGGTGGCTGAGGTCCTGGAAGGCAAAGGAGCAGGGAAGAAAGGCCGTTTTCAGGGCAAGGCCACCAAGATGAGCCGGCGGATGGAGGCGCAGGCGCTTCTCCAGGACTACATCAGCACGCAGAGTGCTAAGGAGTGAGGGCTTAGGGCACTCACCTCCTGTTTCCACAGGAATCTTTTGGTCAATAAAATAGATTGACTCAGAA

Publications

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