Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name HNRNPH3P1
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr10). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:80528922-80531501  UCSC
Coordinates (T2T) chrX:78962719-78965299  UCSC
Coordinates (hg19) chrX:79784421-79787000  UCSC
Strand +
Parental Sequence NM_001322449.2
Parental seq. overlap 1596 bp
Parental seq. overlap (%) 63.4%
Genomic Region Intergenic
Retrocopy Summary HNRNPH3P1, located on chrX:80528922-80531501, is a retrocopy of the parental gene HNRNPH3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name HNRNPH3
Full Name heterogeneous nuclear ribonucleoprotein H3
Also known as 2H9|HNRPH3
Coordinate chr10:68331693-68343196
Strand +
Gene summary This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Several alternatively spliced transcript variants have been noted for this gene, however, not all are fully characterized. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes HNRNPH3P1
Bonobo Pan paniscus HNRNPH3P1
Gorilla Gorilla gorilla HNRNPH3P1
Orangutan Pongo abelii HNRNPH3P1
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>HNRNPH3P1
AACAGTGACTGGGACCATATGATAGATCAACAGGAGACAGGAGGGTTATTATAGAGTTGGATGTGAAAGTATGTATAACAGAATGTGATGAGGAGGTAATGGATATGATGATGTTTATGAAGGTTTTCATAACTATGGTGGCTACAACAATTATGGCTATGGAAATAATGGCTTCGATGACAGAATGATAGAAGAGGTATGAGAGGACATGGCTATGGCAGAGCTAATGATGCAAGTTCAGGTTTTCATGGTGGTCATTTCTTTTGTATATTAGAGGGTTGCCTTTTTATGCAACTGAAAATAACATTGCTAATTTCTTCTCACCACTAAATCCAGTATGAATTCATATTGATATTGAAGCTAATGGCGGAGCAACAGAAGTAGATATAGAGTTTGCGACATATAAAGATGCGGTAGTTAAATTGCCACTGGAAATATTTTTCTATATCAGTGCTCTTTCAACTGTGATCCACAAATTGTGCTAACAATAAACTCTTTGTTATGGAAAAAAAAGGAAAAAAAAGATGCAGTAGTTGCCGTGTCTAAACATGAAAAAAAAAATGCAGCATTGATAAATTAAACTATTTTGAATTCTGCTCTGGAATGAGAGGTTCTGGAATGGGAGGCCACAGCAGAGATGGAATGAATAATCAAAGAGGTTATGGCTCTGTTGTAAAAATGAAAATGGGGAACAGTTACATGGAAAATATGGTGCTGCTGATGGCTTGGGTGTTTATGGCCATGGTGGTGGAGGCAGTGGAGGTTACTATAGGCAAGGCAGCATGAATGGAGGTAAATGGTGTGGAATGTACTGAAAGCATAACAACCAACATACAAGTCTTGACAACAGCATCTAGTCTACTAGACTTTCTTACAGATTTAATTTCTTTTGTATTTTAAGAACTTTATAATGAGCTTGGACTTTATAATGGCTTAATGACTGAAGGAATGTGTTTTCAAAATATTATTTGGTAAAGCAACGGATTGCAATGGGAAAATCTGTTTTCTGTAGGTTTTATTTGTTGCATACTTTGAATTAAAAATAATTTTTATATTTAAACCACCGATGTTGAAATTTTTATATACTAGTTACTTCTAAAAATGTCTTGCTTTCATAAGATTTGGATTGATGTATTTTACTATTAGTTCTACAAGAAGTAATGTGCTATAATTTCAGAGGATAATGATTCGCCTCTGCATAAACTGAAAGTCTTAAGCAGACATCTGGAACTGAGCTTGACAAATAATTAGTGCAACCTTTTTCTTTAATTTCTCCTGGAAAACACAGTAAGTATAAAGCTTAAAGATGAAGAGGCTTCAGGAGTATAAATTCAGCTAATTATTTCTATATTTGTTATTCTTTTTCAAAGGTCATTTATCAAGCACAGTTCTGAAATGTTGATAATCTAAGAGGTAACTTAGATACTGAATATTCATAATTGTGTTGACTAGGGATGGGAGTGCTGGAAGTTTGAATTCGAGCCCTATATTTTGGAGTAAAATCCCTTCAGCTGTTGGCCAAAATATGAAAAAATATTTCCAAAAAAGTGATAGTTGTGAGTTATTTCAAGAAGTCTTAGAATAGGGTTAAGATTCTTAGTGACACAAGAATTCAGTATAAGTACATGGGTATTCACTATGGAGTATAATTCTTACAAATGTCTTTGCAGTTTTCTGCTCAAAAGAACATACGGTTATGACTTTTTAAAAATGTAAACAAGAAGTTTATGTTATGGTCAATTAAAACAAACCTGCAGTTGGATTTTGCACCTGTTATCTGCTTAGAGTTTTAGTTAAAAATATTATAAGTAGCAAGAAAAATGTGCTTTTTAATTTTAATAACTTTGATCAATATTGATTTTTTCCAAATTGGCTAATGAATCAAAATGAAACTTGTCAATGTAAATTCAGTGATTAATCTTCTTACTTGCTTCTGCCAGAAATGTTAATGTGATAAATGTCAATGTGGGAG
>NM_001322449.2
GACGCAGATTCCCAAGATGAGAGAGGCTGGAGCTGGGGGAGGAAAGCCAATGGCGACGAAGGTGCTCAACTCCCAAATCCAGGACAAAGGAGGCAGACGGCCTCCTTTGTAATTCTGCCGCCCGGTGGCGAAGGGTTTTAAGCCAGGCTTGGCTGCTGACGGGAGGGGGAAGGGGCGTACTCTCCCTAGCTTTCTGGTCTCTAGGGCAGCTAGATAAACGGAAAGTCTCCTGGGAGGAATAAAGGACGCTTAGCCGGCCCTTATATTCCAGATTTGGAACTTCGAAAAGACATTTAAATCAAACGGTATTGAGATGGATTGGGTTATGAAACATAATGGTCCAAATGACGCTAGTGATGGGACAGTACGACTTCGTGGACTACCATTTGGTTGCAGCAAAGAGGAAATAGTTCAGTTCTTTCAAGGTATATTGAGATCTTCAGAAGTAGCAGGAGTGAAATCAAAGGATTTTATGATCCACCAAGAAGATTGCTGGGACAGCGACCGGGACCATATGATAGACCAATAGGAGGAAGAGGGGGTTATTATGGAGCTGGGCGTGGAAGTATGTATGACAGAATGCGACGAGGAGGTGATGGATATGATGGTGGTTATGGAGGTTTTGATGACTATGGTGGCTATAATAATTACGGCTATGGGAATGATGGCTTTgatgacagaatgagagatggaagagGTATGGGAGGACATGGCTATGGTGGAGCTGGTGATGCAAGTTCAGGTTTTCATGGTGGTCATTTCGTACATATGAGAGGGTTGCCTTTTCGTGCAACTGAAAATGACATTGCTAATTTCTTCTCACCACTAAATCCAATACGAGTTCATATTGATATTGGAGCTGATGGCAGAGCCACAGGAGAAGCAGATGTAGAGTTTGTGACACATGAAGATGCAGTAGCTGCCATGTCTAAAGATAAAAATAACATGCAACATCGATATATTGAACTCTTCTTGAATTCTACTCCTGGAGGCGGCTCTGGCATGGGAGGTTCTGGAATGGGAGGCTACGGAAGAGATGGAATGGATAATCAGGGAGGCTATGGATCAGTTGGAAGAATGGGAATGGGGAACAATTACAGTGGAGGATATGGTACTCCTGATGGTTTGGGTGGTTATGGCCGTGGTGGTGGAGGCAGTGGAGGTTACTATGGGCAAGGCGGCATGAGTGGAGGTGGATGGCGTGGGATGTACTGAAAGCAAAAACACCAACATACAAGTCTTGACAACAGCATCTGGTCTACTAGACTTTCTTACAGATTTAATTTCTTTTGTATTTTAAGAACTTTATAATGACTGAAGGAATGTGTTTTCAAAATATTATTTGGTAAAGCAACAGATTGTGATGGGAAAATGTTTTCTGTAGGTTTATTTGTTGCATACTTTGACTTAAAAATAAATTTTTATATTCAAACCACTGATGTTGATACTTTTTATATACTAGTTACTCCTAAAGATGTGCTGCCTTCATAAGATTTGGGTTGATGTATTTTACTATTAGTTCTACAAGAAGTAGTGTGGTGTAATTTTAGAGGATAATGGTTCACCTCTGCGTAAACTGCAAGTCTTAAGCAGACATCTGGAATAGAGCTTGACAAATAATTAGTGTAACTTTTTTCTTTAGTTCCTCCTGGACAACACTGTAAATATAAAGCCTAAAGATGAAGTGGCTTCAGGAGTATAAATTCAGCTAATTATTTCTATATTATTATTTTTCAAATGTCATTTATCAGGCATAGCTCTGAAACATTGATGATCTAAGAGGTATTGATTTCTGAATATTCATAATTGTGTTACCTGGGTATGAGAGTGTTGGAAGCTGAATTCTAGCCCTAGATTTTGGAGTAAAACCCCTTCAGCACTTGACCGAAATACCAAAAATGTCTCCAAAAAATTGATAGTTGCAGGTTATCGCAAGATGTCTTAGAGTAGGGTTAAGGTTCTCAGTGACACaagaattcagtattaagtacataggtatttactatggagtatAATTCTCACAATTGTATTTTCAGTTTTCTGCCCAATAGAGTTTAAATAACTGTATAAATGATGACTTTAAAAAAATGTAAGCAACAAGTCCATGTCATAGTCAATAAAAACAATCCTGCAGTTGGGTTTTGTATCTGATCCCTGCTTGGAGTTTTAGTTTAAAGAATCTATATGTAGCAAGGAAAAGGTGCTTTTTAATTTTAATCCCTTTGATCAATATGGCTTTTTTCCAAATTGGCTAATGGATCAAAATGAAACCTGTTGATGTGAATTCAGTTATTGAACTTGTTACTTGTTTTTGCCAGAAATGTTATTAATAAATGTCATTGTGGGAGATAATA

Publications

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