Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RNF19BPX
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:90208902-90209897  UCSC
Coordinates (T2T) chrX:88649949-88650944  UCSC
Coordinates (hg19) chrX:89463901-89464896  UCSC
Strand -
Parental Sequence NM_001127361.3
Parental seq. overlap 734 bp
Parental seq. overlap (%) 26%
Genomic Region Intergenic
Retrocopy Summary RNF19BPX, located on chrX:90208902-90209897, is a retrocopy of the parental gene RNF19B. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RNF19B
Full Name ring finger protein 19B
Also known as IBRDC3|NKLAM
Coordinate chr1:32932498-32965266
Strand -
Gene summary This gene encodes a multi-pass membrane protein containing two RING-type and one IBR-type zinc finger motifs. The encoded protin is an E3 ubiquitin-protein ligase that plays a role in the cytotoxic effects of natural killer (NK) cells. Alternative splicing results in multiple transcript variants. There are pseudogenes for this gene on chromosomes X and Y in a possible pseudoautosomal region. [provided by RefSeq, Jul 2014]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RNF19BP1
Gorilla Gorilla gorilla RNF19BP1
Orangutan Pongo abelii RNF19BP1
Golden snub-nosed monkey Rhinopithecus roxellana RNF19BP1
Marmoset Callithrix jacchus RNF19BP1
Bonobo Pan paniscus Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RNF19BPX
CGGTGAGATGAGTGAAAATTTATGTATTTTATCTTAAAGATTCTCTGGTTATAGGTTTCCTTCAGAGAAATTCTGAGATATTTGCAATTTCTTACTAGATAAAACATCAAAATTTTGCCCTGATTCCCTCTCCTTTCTCCCCTTCCTATTTTTTTTTTAGTTTTAATTTATTGGTTAAACTAATGGTAGCAATCTTTGAGGTATGTCTAAGAATGTACATAGGTATGTGTGTATATTATGTATGTGGTAACATATTACTGAAGGAAACATTTTAATAAAGATTTCTGCCATATTTTCAAAAACCCTCTGGCTTCAGATTCTGGGGCAAGAAGCTGTAAGAAAATTACTTGGCAGCTGTGCGCATTAATTGGAGCTCCAGTGGGGATATCTTTCATTGCTACCATTGCTATTCCTGAAATGGTCATCAGCATTCCTGTTTATGTTGACAGGAAGATTCACTGCACGGATAAAGGAAAGCAAACCTCCAACACAAGAGAAATTTGGCTATCACAGGAGGAATGACTTTGTCAGTGATTGCATCCTCAGTTATTACTGCAGTTAGTATTGCTTTTGGCATCCCAATTATGCTGGCATATGTCAATGTGACTGGCTAATTTGTCTCTCTCATGGAGGCTGCTGTGGTGTTAGCACAGTTGACCAAAAGGGAAGGAAAATTGAATCAAATGAAGATTATTGTCCAATCACAATGTCAGATGCCTGGCAAGCCCTCAAGGGTCCAAGCACTGGGGAAAGCAGCAATGAAGGCCTGACTAGTGTATTCAGCACCAGTGGAAGCCCTACAGATGGACCCCCCTTGACCTCTAGAGCCCAAGGGTGCACTGGGCCCAGGTGTCCATATGAACTTCTCTGCCCCAGCCGAGGGGCAGTCTGTCTTAAAGACAAAAGGTGCCGAAGCCAGAATTTGAAATTGAATAAATGTTCTGAGAAGCACAATTGTTGTGACTGCAACTTTCAAATCt
>NM_001127361.3
ATCGCCGGGAGggcggttgaggcggtggtggcggcgtcggcggcggccgggcgctggctgaggggcgctgaggcgggagctgtggcggcgCTGGGCGCCCCTGGCTCCTCGGCCTCTGCCGGCCATGGGCTCCGAGAAGGACTCCGAGTCGCCGCGCTCCACATCGCTACATGCGGCCGCACCCGACCCTAAGTGCCGCAGCGGCGGCCGGCGCCGGCGCCTCACCTTGCACAGCGTCTTCTCTgcctcggcccgcggccgccgcgcccgggccaagccgcaggccgagccgccgcccccggctgcgcagccgccgcccgccccggcccctgccgcggcccagggcccgccgcccgaggcgctgcccgccgagccggccgccgaggccgaggcggaggccgcggcggcggcggcggAGCCTGGGTTCGACGATGAGGAGGCGGCGGAGGGCGGTGGCCCGGGCGCGGAGGAGGTGGAGTGTCCGCTGTGCCTGGTGCGGCTGCCGCCTGAGCGGGCCCCGCGCCTCCTCAGCTGTCCGCACCGCTCGTGCCGGGACTGCCTCCGCCACTACCTGCGCCTGGAGATAAGCGAGAGCAGGGTGCCCATCAGCTGCCCCGAGTGCAGCGAGCGACTCAACCCGCACGACATCCGCTTGCTGCTCGCCGACCCGCCGCTTATGCACAAGTACGAGGAGTTCATGCTGCGCCGCTACCTAGCCTCGGACCCCGACTGCCGCTGGTGCCCGGCCCCGGACTGCGGTTATGCTGTTATTGCCTATGGCTGTGCCAGCTGCCCGAAGCTAACTTGTGAGAGGGAAGGTTGCCAGACTGAGTTCTGCTACCACTGCAAGCAGATATGGCATCCAAATCAGACATGCGATATGGCCCGTCAACAGAGGGCCCAGACTTTACGAGTTCGGACCAAACACACTTCAGGTCTCAGTTATGGGCAAGAATCTGGACCAGATGACATCAAGCCATGCCCACGATGCAGTGCATACATTATCAAGATGAATGATGGAAGCTGTAATCACATGACCTGTGCAGTGTGTGGCTGTGAATTCTGTTGGCTTTGTATGAAAGAGATCTCAGACTTGCATTACCTCAGCCCCTCTGGCTGTACATTCTGGGGCAAGAAGCCATGGAGCCGTAAGAAGAAAATTCTTTGGCAGCTGGGCACGTTGATTGGTGCTCCAGTGGGGATTTCTCTCATTGCTGGCATTGCCATTCCTGCCATGGTCATTGGCATTCCTGTTTATGTTGGAAGGAAGATTCACAGCAGGTATGAGGGAAGGAAAACCTCCAAACACAAGAGGAATTTGGCTATCACTGGAGGAGTGACTTTGTCGGTCATTGCATCCCCAGTTATTGCTGCAGTTAGTGTTGGTATTGGTGTCCCCATTATGCTGGCATATGTTTATGGGGTTGTGCCCATTTCTCTTTGTCGTGGAGGCGGCTGTGGAGTTAGCACAGCCAACGGAAAAGGAGTGAAAATTGAATTTGATGAAGATGATGGTCCAATCACAGTGGCAGATGCCTGGAGAGCCCTCAAGAATCCCAGCATTGGGGAAAGCAGCATTGAAGGCCTGACTAGTGTATTGAGCACTAGTGGAAGCCCTACAGATGGACTTAGTGTTATGCAAGGTCCTTACAGCGAAACGGCCAGCTTTGCAGCCCTCTCAGGGGGCACGCTGAGTGGCGGCATTCTCTCCAGTGGCAAGGGAAAATATAGCAGGTTAGAAGTTCAAGCCGATGTCCAAAAGGAAATTTTCCCCAAAGACACAGCCAGTCTTGGTGCAATTAGTGACAACGCAAGCACTCGTGCTATGGCCGGTTCCATAATCAGTTCCTACAACCCACAGGACAGGTTTAGCATGATCCATGCATGACTCAGCAAAGTGGATTTTGTCTCCACAGAGAATGCAACAATATGGAAATCCAAGTGGACATTGAAGCCAAACCAAGCCACTATCAGCTGGTGAGTGGAAGCAGCACGGAGGACTCGCTCCATGTTCATGCTCAGATGGCAGAGAATGAAGAAGAAGGTAGTGGTGGCGGAGGCAGTGAAGAGGATCCCCCCTGCAGACACCAAAGCTGTGAACAGAAAGACTGCCTGGCCAGCAAACCTTGGGACATCAGCCTGGCCCAGCCTGAAAGCATCCGCAGTGACCTAGAGAGTTCTGATGCACAGTCAGACGATGTGCCAGACATCACCTCAGATGAGTGTGGCTCCCCCCGCTCCCATACTGCAGCCTGCCCCTCGACCCCCAGAGCCCAAGGTGCACCGAGCCCAAGTGCCCATATGAACCTCTCTGCCCTAGCCGAGGGACAAACTGTCTTGAAGCCAGAAGGTGGAGAAGCCAGAGTATGAAGTGGAATGAATGCTCCTGTTCTGAGAAGCACACTTGTAACTGCATCTTTTGGAAtttttttttttttttttCCAAGGGGTAGAGATTTATGTATTTTATTTCACAGATTCTCTGGTCACAGGTTTTTGCCCAGGGAAATTCTGAGAAATTCACAATTTCTTACCAGATAAAACATGAAAAGTTTGCCGTTAGTTCCCCTCCCCTCCCCTCCCTCTTTTTAGTTTTAATTTATTGGTTAAACTGATGGCAGCAATCCATGAGGTGTGTCAAAGAGTGTACATATGTATGTGTGTATATTGAATGCTAAACATATTACTGAAAGACACATTTTAATAAAGATTTCTGTCATAATTCAA

Publications

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