Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name DLGAP5P2
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr14). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:93042488-93042936  UCSC
Coordinates (T2T) chrX:91492758-91493206  UCSC
Coordinates (hg19) chrX:92297487-92297935  UCSC
Strand +
Parental Sequence NM_014750.5
Parental seq. overlap 383 bp
Parental seq. overlap (%) 13.3%
Genomic Region Intergenic
Retrocopy Summary DLGAP5P2, located on chrX:93042488-93042936, is a retrocopy of the parental gene DLGAP5. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name DLGAP5
Full Name DLG associated protein 5
Also known as DLG7|HURP
Coordinate chr14:55148130-55191585
Strand -
Gene summary Predicted to enable microtubule binding activity. Predicted to be involved in several processes, including centrosome localization; kinetochore assembly; and mitotic spindle organization. Located in several cellular components, including centrosome; cytosol; and mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes DLGAP5P1
Bonobo Pan paniscus DLGAP5P1
Gorilla Gorilla gorilla DLGAP5P1
Orangutan Pongo abelii DLGAP5P1
Gibbon Nomascus leucogenys DLGAP5P1
Green monkey Chlorocebus sabaeus DLGAP5P1
Rhesus Macaca mulatta DLGAP5P1
Golden snub-nosed monkey Rhinopithecus roxellana DLGAP5P1
Crab-eating macaque Macaca fascicularis Without Homology
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>DLGAP5P2
CTCCTGAATGCAGGAACAGCATAATAGGAGATACTCAGTGCCCTGGATTACCACACTTAATTGAAATAAACCATGATGTAAATAAAATAAATGTTGAGATGGATTGTTTATCCAGTGAAATAATGAGTTTACTTCTTCTTGCTGATGGAGTAGCAGTTAATACTAACAAAAAAGAAGAAATTTCAGATGTTGTGGTAAGAAGGAAACTAAATTTTTCAATTATACCTCAGAATGTTTTAATGAGTAGCTCTGAAAAAATTATGCCATCACAAAATGACATCTCACAAACTAACATTTCTCAGTCAGTTCTATTTGATAATAAAAATCTCATTACTGAATGCCACCTTGTTAATTCAACCTAAACTGTCATAGTCCATTCGTTTAGCTGGAGAGACATCAAGAACATGCCAGACACATTTTATTTGGTGGTAAGCTGATTGCTTTTTCAC
>NM_014750.5
AAGTTTGAATTTCGTGGAGGCTCGGGTTGTGAGGGTTCCTGCTTCGGAGTCGGCGGTGGTCGTCCAGACCGAGTGTTCTTTACTTTTTGTTTGGTTGAGGTTTCACGCTAGAAGGTGGCTCAGGATGTCTTCATCACATTTTGCCAGTCGACACAGGAAGGATATAAGTACTGAAATGATTAGAACTAAAATTGCTCATAGGAAATCACTGTCTCAGAAAGAAAATAGACATAAGGAATACGAACGAAATAGACACTTTGGTTTGAAAGATGTAAACATTCCAACCTTGGAAGGTAGAATTCTTGTTGAATTAGATGAGACATCTCAAGGGCTTGTTCCAGAAAAGACCAATGTTAAGCCAAGGGCAATGAAAACTATTCTAGGTGATCAACGAAAACAGATGCTCCAAAAATACAAAGAAGAAAAGCAACTTCAAAAATTGAAAGAGCAGAGAGAGAAAGCTAAACGAGGAATATTTAAAGTGGGTCGTTATAGACCTGATATGCCTTGTTTTCTTTTATCAAACCAGAATGCTGTGAAAGCTGAGCCAAAAAAGGCTATTCCATCTTCTGTACGGATTACAAGGTCAAAGGCCAAAGACCAAATGGAGCAGACTAAGATTGATAACGAGAGTGATGTTCGAGCAATCCGACCTGGTCCAAGACAAACTTCTGAAAAGAAAGTGTCAGACAAAGAGAAAAAAGTTGTGCAGCCTGTAATGCCCACGTCGTTGAGAATGACTCGATCAGCTACTCAAGCAGCAAAGCAGGTTCCCAGAACAGTCTCATCTACCACAGCAAGAAAGCCAGTCACAAGAGCTGCTAATGAAAACGAACCAGAAGGAAAGGTGCCAAGTAAAGGAAGACCTGCCAAAAATGTAGAAACAAAACCCGACAAGGGTATTTCTTGTAAAGTCGATAGTGAAGAAAATACTTTGAATTCACAAACTAATGCAACAAGTGGAATGAATCCAGATGGAGTCTTATCAAAAATGGAAAACTTACCTGAGATAAATACTGCAAAAATAAAAGGGAAGAATTCCTTTGCACCTAAGGATTTTATGTTTCAGCCACTGGATGGTCTGAAGACCTATCAAGTAACACCTATGACTCCCAGAAGTGCCAATGCTTTTTTGACACCCAGTTACACCTGGACTCCTTTAAAAACAGAAGTTGATGAGTCTCAAGCAACAAAAGAAATTTTGGCACAAAAATGTAAAACTTACTCTACCAAGACAATACAGCAAGATTCAAATAAATTGCCATGTCCTTTGGGTCCTCTAACTGTTTGGCATGAAGAACATGTTTTAAATAAAAATGAAGCTACTACTAAAAATTTAAATGGCCTTCCAATAAAAGAAGTCCCATCACTTGAAAGAAATGAAGGTCGAATTGCTCAGCCCCACCATGGTGTGCCATATTTCAGAAATATCCTCCAGTCAGAAACTGAGAAATTAACTTCACATTGCTTCGAGTGGGACAGGAAACTTGAATTGGACATTCCAGATGATGCTAAAGATCTTATTCGCACAGCAGTTGGTCAAACAAGACTCCTTATGAAGGAAAGGTTTAAACAGTTTGAAGGACTGGTTGATGATTGTGAATATAAACGAGGTATAAAGGAGACTACCTGTACAGATCTGGATGGATTTTGGGATATGGTTAGTTTTCAGATAGAAGATGTAATCCACAAATTCAACAATCTGATCAAACTTGAGGAATCTGGGTGGCAAGTCAATAATAATATGAATCATAATATGAACAAAAATGTCTTTAGGAAAAAAGTTGTCTCAGGTATAGCAAGTAAACCAAAACAGGATGATGCTGGAAGAATTGCAGCGAGAAATCGCCTAGCTGCCATAAAAAATGCAATGAGAGAGAGAATTAGGCAGGAAGAATGTGCTGAAACAGCAGTTTCTGTGATACCAAAGGAAGTTGATAAAATAGTGTTCGATGCTGGATTTTTCAGAGTTGAAAGTCCTGTTAAATTATTCTCAGGACTTTCTGTCTCTTCTGAAGGCCCTTCTCAAAGACTTGGAACACCTAAGTCTGTCAACAAAGCTGTATCTCAGAGTAGAAATGAGATGGGCATTCCACAACAAACTACATCACCAGAAAATGCCGGTCCTCAGAATACGAAAAGTGAACATGTGAAGAAGACTTTGTTTTTGAGTATTCCTGAAAGCAGGAGCAGCATAGAAGATGCTCAGTGTCCTGGATTACCAGATTTAATTGAAGAAAATCATGTTGTAAATAAGACAGACTTGAAGGTGGATTGTTTATCCAGTGAGAGAATGAGTTTGCCTCTTCTTGCTGGTGGAGTAGCAGATGATATTAATACTAACAAAAAAGAAGGAATTTCAGATGTTGTGGAAGGAATGGAACTGAATTCTTCAATTACATCACAGGATGTTTTGATGAGTAGCCCTGAAAAAAATACAGCTTCACAAAATAGCATCTTAGAAGAAGGGGAAACTAAAATTTCTCAGTCAGAACTATTTGATAATAAAAGTCTCACTACTGAATGCCACCTTCTTGATTCACCAGGTCTAAACTGCAGTAATCCATTTACTCAGCTGGAGAGGAGACATCAAGAACATGCCAGACACATTTCTTTTGGTGGTAACCTGATTACTTTTTCACCTCTACAACCAGGAGAATTTTGAATTTAAAAATAAATCCAAACATTTTCCTTCATATTATCAATGCTTATATATTCCTTAGACTATTGAAATTTTGGAGAAAATGTATTTGTGTTCACTTCTATAGCATATAATGTTTTAATATTCTGTGTTCATCAAAGTGTATTTTAGATATACTCTTTCTCAAGGGAAGTGGGGATATTTTGTACATTTTCAACACAGAATAAAAAATGTACTGTG

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