Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name EIF5P1
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr14). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrX:9817297-9819678  UCSC
Coordinates (T2T) chrX:9399835-9402216  UCSC
Coordinates (hg19) chrX:9785337-9787718  UCSC
Strand -
Parental Sequence NM_001969.5
Parental seq. overlap 1974 bp
Parental seq. overlap (%) 33.9%
Genomic Region Intragenic (SHROOM2)
Retrocopy Summary EIF5P1, located on chrX:9817297-9819678, is a retrocopy of the parental gene EIF5. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name EIF5
Full Name eukaryotic translation initiation factor 5
Also known as EIF-5|EIF-5A
Coordinate chr14:103334237-103345025
Strand +
Gene summary Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes EIF5P1
Bonobo Pan paniscus EIF5P1
Gorilla Gorilla gorilla EIF5P1
Orangutan Pongo abelii EIF5P1
Gibbon Nomascus leucogenys EIF5P1
Green monkey Chlorocebus sabaeus EIF5P1
Crab-eating macaque Macaca fascicularis EIF5P1
Rhesus Macaca mulatta EIF5P1
Baboon Papio anubis EIF5P1
Golden snub-nosed monkey Rhinopithecus roxellana EIF5P2
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>EIF5P1
TGGCTCCGTATCCAGCAGTGAGACACCACCACCAAAGAAATTAGCCCTCCTCCACATACAGTGGAAGAAGAGGAGGATGACTGGGGGGAAGATACAACTGAGGAAGCTCAAAGGTGCAGAATGGATGAAATCAGTGATCATGCAAAAGTTCTGATACTCCATGATGATTTGGAAAAAACAGTTGAGGAGCGGGCCAACATCCTGTTTGATTTTGTGAAGAAAAAGAAAGAAGAGGGTATCATTGATTTATGTGACAAAGAAATTGTTACTGAAGCAGAAGGACTGGATGTTAAAGCCATGGGCCCTCTTGTTCTGACTGAAGTTCTTTTTAAAGAGGAGATTAGAGAACACATAAGAAATACAGGCACCATTTCTTATGATTTTGTCACAACAACAAAAAAGCTCAATGGTACCTTCTTCATGGCTTTACGTGTGGGGTAGCAATGCACCAAGCTCAGCTTATCTCTAAGATTCCAAATATCTTGAAGGAGATGTATGATGTAGATTTTTTAGAAGAAGAGGTCGTCATCAGCTGGTCGGAAAAAGGCCTTTAAGAAACATGTCTCAAAAGAACCTGCCAAAGAGATTCGTGTCAAAGTAGAACCATTTATAAAATGGAGGCAGAGGAAGAATCTTCTGGTGGTGAAGAAGATGAAGATGAGAACATTGAGGTGGTGTATTAGAAGACTGCCAGTGTACCTAAAGTTGAAACTGTAAAGTCCAACAACAAGGATGATGACATTGATATTGATGCCATTTAATGGGATGGATACAACCTAGCTTAACATTGTAATGCTGCAAATTCTTCTCCGTTACCAGCCAGCACAACATGTATGCGCAAAAGCTAAAATGGCTTAACATCAAGCTACACTATACACTAAAAATCCATTACTGTGAGTGGTCTGTAATTAAGCTCAATGAGACATCCAGGGAGTCCATACACACATCAGTGAGCAGATGTAGTTTGCTTATTTATAGCATGTTTCTTTTTGAAAAACTGGTGGTGGACACATTTGGATCACATTTATACAGTTATAAAAATAAAGATTTGATTTTGGCCATTCTTCAGATATTTGGCTCTGAATGACTTAAGCTGAAGTATCTGGCTCCATTTTCAAATGTTACATCATCGTTTCACCTGATGAGCATTCTTGGAGGCTGCTAGATATTGTTAGGTACTGAGGCTGTAAAGAGGTCTTCAACAGGATGTAAGGCAAACTTATTTGTAATTACCTTATTCAGCCCATTAAGAAATAGTACTACATAAGTTTTATCTCTAGTCCCTCCAATTGGCATCTGGTAATGTACACTGCGAGGTAGACTGATAACCAAATGACAGTGCAACATCCTACTGAGAAGTAAATATGACCTGAGTGTCCTAGAAATAATTTAACAGCAGGTTTTGAAACTTAGAGAGTTGTTTTCTCATTTCATGTATACTTGCCCTAAATTGTAGTCTTTGAAGTCGTGTGCACTGCACGTTGGGTGAGCCAGGGAAGTTATTACATTAACAACCATTTTGTGTGTACGCAGTAGTTGCTTCGTACTGAGAGAACTTGCTTTGGGGTACAATTAAAAAATAAACTGATTTTATTTGGGGGAAACAGGGAAGGGTGCACTTACTAGTAAACCTAAGCATTAATTTTCAGCTTTTGCCCTTATGATTTAAATTACAATTCCAAAATGTTTAGACATACTGAGAGCTTTTGCGCAGCCATTAGTACCTGTATTGGGGAAACATAGCATACAAGCAAGACGCTTACAGCCTCAGTGGTGAAAATGTTTTCACATTAGAGACCGAGAACTTTTGCAGTTGTTTATGTCATCCCTTCTTCTCCAGACAGAAGATATAAAAAAGCTGCAATCAAAGATCTCTTCATCTTATTGATAAAGCCACCAATAAGCCAAAATGTCTGTCAACGTCAACCCCAGCATATCAGACCAGTTCTATTACAAGATGCCCTGTCTGATTGCCAAGGTTGAGGGCAAAGGAAATGGAATCAAGACAGTTATAGTCAACATGACTGACACTGCAAAGGCGCTTAATTGGCCTCCAAGGTATCCCACCAAGTATTTTGGTGGGATACATTGTTACATTGTGAATGGATCTCAGGAGGCCAATAAGCTGCAAGACATATTGGATGGACTCATTAAAAAATTTGTTCTCTGTCCTGAATGTGAGAATCCTGAAACAGATATGCATGTCAAGCCAAAGCAGCAAACAATAGGTAATTCTTATAAAGCCTGTGGCTATCGAGGCATGCTTGACACACATCATAAACTCTGCACATTCATTCTCAAAAACCCACCTGAGAATAGTGACAGTGGTACa
>NM_001969.5
AGTCAGAGCGAGAACATTCCAGAGGTCGCCCAGCTCCGGCGCTGACGGGTGTGGACCGCGGACGTCGCTGGGACAGCCCCTCCCCGCTGCTCGGCGGCGGCACCTGGCCCGGCCGCTCCTCGCTGCGCTTCGCCTCCGCCTCCTCGGACTCGGACTCGGGTTTATATCGCGCCTCACTTCATCCCAGTCCCGGGCGAGCAGCGTTGGGTTTATGTCTTTATTTGACGAAAACGAGCTGTTGCGCAGCCATTGGTACCTGTATTGGGGAAACATAGCATACAAGCAAGAAGCTTACAGCCTCAGTGGCGAAAATTTTTTCATGTCAGAGACCGAGAACTCTTGCAGTCGTTTATGTCATCCCTTCTTCTCCAGACAGAAGATACCAAAAAGTTGCAATCAAAGATCTCTTCATCTTATTGATAAAGCCACTAATAAGCCAAAATGTCTGTCAATGTCAACCGCAGCGTGTCAGACCAGTTCTATCGCTACAAGATGCCCCGTCTGATTGCCAAGGTTGAGGGCAAAGGCAATGGAATCAAGACAGTTATAGTCAACATGGTTGACGTTGCAAAGGCGCTTAATCGGCCTCCAACGTATCCCACCAAATATTTTGGTTGTGAGCTGGGAGCACAGACCCAGTTTGATGTTAAGAATGACCGTTACATTGTCAATGGATCTCATGAGGCGAATAAGCTGCAAGACATGTTGGATGGATTCATTAAAAAATTTGTTCTCTGTCCTGAATGTGAGAATCCTGAAACAGATTTGCATGTCAATCCAAAGAAGCAAACAATAGGTAATTCTTGTAAAGCCTGTGGCTATCGAGGCATGCTTGACACACATCATAAACTCTGCACATTCATTCTCAAAAACCCACCTGAGAATAGTGACAGTGGTACaggaaagaaagaaaaagaaaagaaaaacagaaagggcaaagacaaggaaaaTGGCTCCGTATCCAGCAGTGAGAcaccaccaccaccaccaccaccaAATGAAATTAATCCTCCTCCACATACAATGGAAGAAGAGGAGGATGATGACTGGGGAGAAGATACAACTGAGGAAGCTCAAAGGCGTCGAATGGATGAAATCAGTGACCATGCAAAAGTTCTGACACTCAGTGATGATTTGGAAAGAACAATTGAGGAGAGGGTCAATATCCTCTTTGATTTTGTTAAGAAAAAGAAAGAAGAGGGTGTTATTGATTCATCTGACAAAGAAATCGTTGCTGAAGCAGAAAGACTGGATGTAAAAGCCATGGGCCCTCTTGTTCTAACTGAAGTTCTTTTTAATGAGAAGATTAGAGAACAGATTAAGAAATACAGGCGCCATTTCCTACGATTTTGTCACAACAACAAAAAAGCCCAACGGTACCTTCTTCATGGTTTGGAGTGTGTGGTAGCAATGCATCAAGCTCAGCTTATCTCCAAGATTCCACATATCTTGAAGGAGATGTACGATGCAGACCTTTTAGAAGAAGAGGTCATCATCAGCTGGTCGGAAAAGGCCTCTAAGAAATATGTCTCCAAAGAACTTGCCAAAGAGATTCGTGTCAAAGCAGAACCATTTATAAAATGGTTGAAGGAGGCAGAGGAAGAATCTTCTGGTGGCGAAGAAGAAGATGAAGATGAGAACATTGAGGTGGTGTATTCGAAGGCTGCCAGTGTACCGAAAGTTGAGACTGTAAAGTCAGACAACAAGGATGACGACATCGATATTGATGCCATTTAAAGGGATGGATGCAACCTAGCTTAACAGTATAATGCTGCAAATTTTCCTCCATTATCAGCCAGAAGTGCAACATGTATGTGCAAAAGCTAAAATGGCTTAACATCATGCTACACTTTACACTAAAAATCTATTACTGTGAGTGGTCTGTTATTAAGCCCAATGAGACATCTAGGGAGTCCATACACATCAGTGAGCAGATGTAGTTTGCTTATTTATAGCATGTTTCTTTTTGAAAAACTAGTGGTGGACACATTTGGATCACATTTATACAGTTATAAAAATAAAGGTTTGATTTTGGTCGTTCTTCAGATGTTTGGCTCTGAATGACTTAAGCTGAAGTAACTGGCTCCTTACTTTAAATGTTCTGCCATCATTTCACCTGATGAGCATTCTTGGAGCCTGCCAGATATTGTTAGGTCCTGGGGCTGCAAAGAGGTCCTCAACAGGATGTAAAGCAAACTTAATTGTAATTAATTTATTCAGCCCATTAAGAAAGTACTAAAGTTTTATCTCTGTAGTTCCTCAAATTGGCATCTGGTAATGTACATTGTGAGGTAGACTGATAATGAAATGACAGTGTAACATCTTAACCAAGAAGTAAATATGACCTCAGTGTCCTATAAATAATGTAAGAGCAGGATTTGAAACTTGGAGAGCTGTTTTCTCATTTCATGTACACTTGCCCCAAATTGTCTTTGAAGTCGTGTGCATTGCACGTTGGATGAGCCAGGGAAATTATTACATTAACAAGCATTTTGTGTGTACGTAGTAGTTACTTTGTACTGAGAGAACTTGCTTTGGGGTGCAATTAATAAACTGATTTTATTTGGGAGAAACAAGGAAGGGTGCACTTAACTAGCAACCTAAGCATGATTTTTCAGCTTTTGCCCTTAGGGTTTAAATTACAATTCCAAAATGTTAGACATACTGTATTTTTTCGTTCAGTGTGGCTTTAATTTTCCCCTCTTGCAGTTTGTTCTGTAATGCCTTTTACATTTGGACACATAGTTTATGCTTTTTAGATTTTGGTTGCTTTCTTGCCAAAATAAGTGTTAACTGTGTTTCAAACTTGAttttctttcctttttcttttttttttcttCCAGAATGTCTTATTTAAAAAGAAAGCTAAAAGCATACTTCTAAGTCAGAGCCTCTATTTTGGTGTAAGACTTGGGATATTTTTTACTTCACATTGAATATAGCCAGGCACCCAAGAAGTCTGATGGCCACCTGAGTGCAGGTGACAAGGACCTGACAGAGCCCATGCAGGGCTTTAGATTTGGACACACAAGAGTTGATAACTTCCTCATGAACTCCTTGCCTGATCTAAACTCATATTATGGGTTCTGACTGTTTGAGTAATCATCTTCAAGGTTAAACCTCTTGGCAGTTACCCTTTTCACAAAGTGCACAGTGGGAATCGAGAATCGATAGGGTTAATTTTGGAGCAGTGGCTTATACCATTCACCTCTGTTTTTTTGTGATTATTTCACAGATAATGAGACCTTAATAACAAATAGGCGTAAAAAAATTTTCACATTGAAATGATAGAAACATTTGATGTAATAAAACTTGGTTGGCTTGATATTTTAAGGAATTGAAACCTAGCAATCTTATTGGAGAGACAAGAATTGGTCTCCAGCTGCCTTTGATCAAGATTCGGGTGCAAGTGGAGCAGGAGCCATATACCTGGAGGGAATGTGCTTTGTCACACCAAAGAGGATTTTTTTTTCTTCAAACTTGTATGTTGCCTAGGTTTCAAATTCTTTGCCGCAAGGCTGATCTGCTTTCATTAACTGGAATTCTGTAGGAGATACTGGTGACCTAAGCTAAGTTGCACTCAGCATACTCAGTGTCAAGCTAATGAGGTTCTATTATAAAGGTTCTACTTTTAATCTGAGGGAAAACATGTTCAGGGCTTCTAGAACACTAAAAAATTTGGCTTAAACCAGTGTTCAGTCTGGTGCCAAACTTCGAATGGAATACAAATTCACATAATCTGAACTTTGTTCACAGGTTATCCTAATAGAGTAATTCTTCACTTTGCTCTATTGAACTGTCTTAAGGATTTGTTTAAACAGCTAAGTTACTTGATTAAAATAATGATAAAATTGTATTTTGTCTTTGCTTTAATATTAAAGTTAACAAGTTTTCATTTTATAATGAGATCAAAGCATTGGAATCTGCCCTGTTTTGTAGCCGTTGCTTTGGATTTGTGTTGGATGTATCCTGCAGTTACACTTGCCAGCCCCACTCACAAAAGTTGTTCATTTCATTGGGTCACTGGCTTTATTTGCTAGTCTTGTCTGTGAACTGAGCATCTGCCTCAGTTTTATTACTTGAAATCTTGGCAGGTGCTTAATAGGGAACATACATACAGCTATGTAACTGTGAATAATTGTATATATCTCTAGTTAAGAATGAGGGAATGGGGAGGTTTGCTTTCTAAACAAGTGCATTCTGAAATTGACTTAAAAATTTTTAGTGTGGGTCCTAAAGTTTAGAGATGGGCAAGGAGGTCTCTAATCCACCGCTTCCCGCTTGAGAAGGGAGGGGTATCAAAATTGAGCCCCAAGCTGTTTGTTCCAGTGTACCAAGCACTGACTTTATGCCTTTGGCCTGGAGATGGCAGAAGTGAAAGCTGGCCATCTGCAAAAAGCAGATAAGTGAGTTTGAACCTTTTGCATTTTGTTAGCTCAGTCAGTCCTCATCGTGGTCCTGAGGCATAGGTACTGTTGTACCAAGGTCACTTATCTAACAAAATAACCCTTCATGTATTTTAAATTTATTTGACAAGTCTGCAGACAATCCTTATCTAACCAGCTATTTTCTTAATTGCTACAGCTTGACCTACCAGTATTCCGGAGTAACCAGCAAATGCAAAGTTGACCTTGTTCCTGCATCATCTTTTTGATGGTTCAAATTTCAGCCTCCCTGACTACTACAAAGCCAGAGCAGTCTTAGTACCAGAAACAGTGTTGCACTTTCGTTGCATGTGCTGtgtgaccccaaggggacagggagtcactttggtcatctctgtccccagtacagatcttgattcatagtgacattccataagtgGGGTGACAGCAAATGACTTGCAGGTAGTCTCATTGTAGGTTTGTGCACCAGAGTGACCCTGTGAGCCTTTGTTAATAGGTTGGGAGCTCAGGGTGTTTATGTCCACCTGTCTGGTCTAGCCAAACAGTTTTTTTCTGGGAATCAAATTTCTGTGGTTTTTATGGCCAGAAATTTTAAGGACTTGTGTGTGCTGGGATATGAGAATAGAAGCTACAGAGTTCTTTTCTTGGGACCTAGACTGGGAGGTGCAATGTCAGGACCTCCAGGTGAATGGTAGGATCTGAGTTGACCCTGCAGTTCGGTTATGCAGTCAATTATTTCTTTTTAAGAGGAGGAGGATTCACTTGGGTGTTGGGATCAAATTTGGATTCTGTCCCAGGCCTTACTGTAAAACTAGGGGATTGCCTTTCCATATCTGCTGGGGGTGGAGACCCTTATGTGCAGCACTCAATCCCACTGGAAGCCTAATGCTGCAGTCAgaagcaatgcctggctggggcagtaggggaaattccacccaattttgctatgagcctaaaacctctttaaaaaCGGTCAGTTAACTAAAAAATAAAAATCAAGTCTTTAGGAGAGTAGAAAACACAATTAACTAAAAAGCAGGGACATCTGAAAGAGACGTAttaagttaacatttttaaaaatccaaatgaaagtaaatggaataaatgtatcaggtaaaggacaagttgtaagcttggatttttaggtctagcaatacactgtttacaagagcatcacctaaaatgtgacaaaagatgttgaaaggatgaaaaaaggtatagtagacatacactaaccaaaaatgtagctctttgaatctcagaaaaaagtagattttaaTAAAGtgtgaaagttgtcaatcaaa

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