Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name AGKP1
Plot displaying the genomic locations of a retrocopy (in chrY) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrY:14639072-14641222  UCSC
Coordinates (T2T) chrY:15545715-15547865  UCSC
Coordinates (hg19) chrY:16750952-16753102  UCSC
Strand +
Parental Sequence NM_018238.4_2
Parental seq. overlap 1658 bp
Parental seq. overlap (%) 45.6%
Genomic Region Intragenic (NLGN4Y)
Retrocopy Summary AGKP1, located on chrY:14639072-14641222, is a retrocopy of the parental gene AGK. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name AGK
Full Name acylglycerol kinase
Also known as CATC5|CTRCT38|MTDPS10|MULK
Coordinate chr7:141551410-141662153
Strand +
Gene summary The protein encoded by this gene is a mitochondrial membrane protein involved in lipid and glycerolipid metabolism. The encoded protein is a lipid kinase that catalyzes the formation of phosphatidic and lysophosphatidic acids. Defects in this gene have been associated with mitochondrial DNA depletion syndrome 10. [provided by RefSeq, Feb 2012]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes AGKP2
Green monkey Chlorocebus sabaeus AGKP2
Rhesus Macaca mulatta AGKP2
Golden snub-nosed monkey Rhinopithecus roxellana AGKP3
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>AGKP1
CCCAGCCCTGCAAATCTCTAGAAGGTGACGATATTCTTTAAAACACTTCGAAATCATTGGAAGAAAATTACAACTGGGCTCTGCCTCCTGGCCTGGGGATGTAATTAGCTGTATAGAAAACACTGTGATAACCTACTAAGGAGAGTAGCCTATCAAGAAGCTCAGGTGTTTGGCAATCAACTCATTTCTCCAAATGCACAAGTGAAGAAGGCAACTGTTTTTCTCAATCCTGCAGCTTGCAAAGGCAAAGCCAGAACTTGATTTGAAAAAAATGCTGCCCTGATTTTACATATATCCAGGATGGATATGTCTATTATTAGGGCAGGTTATGAGGGATAAGTCAAGGAACTCCTGGAACTGATGTTAAACACAGTTGTGATCATTGTTGTAAGAGGAGATGGGACACTGAAGGAGGATGTTACTGGAGTTCTTCAAAGAACAGATGAGGCTACCTTCAGTAAGATTCCCATTGGATTTATCCCACTGGGACGGACCAGTAGTTTGAGTCATACCCTCTTTGCTGAACGTGGAAACAAAGTCCAACATATAACTGATGCCACATTTGCCATTGTGAAAGGAAAGACAGTTCCACTTGATGTCTTGCAGATGCAAGGTGAAAAGGAATAGCCTGTGTTTGCAGTGACTGGCCTTCGATGGGGACCCTTCAGAGATGTTGGCATCAAAGTTAGCAAGTACTGGTATCTTGCGCCTCTAAAAATCAAAGCAGCTCACTTTTTCAGCACTCTCAAAGAGTGGCCTCAGACTCACCAAGCCTATATTTTACACACGGCACCTACAGAGAGATCTCCCAGTGAACCAGAATAGACCCCTGTGCAAAGGCCTTCTTTTTACAGAAGAATATTACAAAGTCTTACATCCTACTGGGCACAACCGGAGCATGCCCTTTCCCAAGATGTGAGCCCAGAGATCTGGAAAGATGTGCAGCTGTCCACCATTGAACTATCCATCACAACACAGAAAAATCAGCTTGACCTGCCAAGCGAAGAAGATTTTATGAACATCTGAATTGAACGAACACCATCAGCAAAGGAGACTTCAGCCAGTGCACTTTGCTTGTTGCCAATGGAGCTGGGGGCTCTTTTGGCATAGACAGTGAAGAGTGTGATGTGAAGCCTGTGGAGGTGAAACTGCTCCCCAGGAAGCTGCAGCTTTTCTATGATCCCAGGAAGAGAGAATAGATGCTGGCAAGCCCCACCCAGAAAGCAGGCAGAAGACAAGTGCTCTGAGACCATACTTTAGGCCACCAGCAGGACCAAAAGGGAACAGATGCCTCAACCATCCCAACAGTGTTGTCAGAGTGTCCCAAGGGCTTTTTCATGGCAAGTAGCCTCTGGCCTTCTCCAGCAGTGCTTCCCAAAGTATACTCTGTCACCTGTTTTGCAATCAGGTTTTGTTAGGGCATATTTTATTTTGGTGTGATGGTTGACCCTCCTAAACACGGACTTTCCTCAGACTGGTTCAAGATGGAAAAGGACTTTCTTCTGTTTTCTCCCAAAGTGCAACCACAGTGCAGAGCCCACAGTGGGCTTAGGCTGCCTGGGCCTTTCCATTCTGGTTCTGTCTTTTGACCATGCTCAGAATTCTGGGGAAAATGCCTTCCTTCCCTGGTGACCTTTTCCTGTTTCTAGGCTTCTCCACAAGTGCTGCTATTTTGTGAGCTCTGGCTCCTGTTTAGCTTTTATATCAGTTCTATCCTCAGTCCAGAAATGTATATGAGGTTGTGTCCCCCTTCAGCCATGGCAACAATATTGTAAAATGCTAGTTTTTATTTTTTTAGGTAGTGCTTTCTAAATGGTTTTAAGTTGTCCCTCAATGCACTTGGAGAAATAGTGTTTTAAAG
>NM_018238.4_2
AGAGCCGCGAGCTGGACCAGCCGTGCAAATCTCTAGAAGATGACGGTGTTCTTTAAAACGCTTCGAAATCACTGGAAGAAAACTACAGCTGGGCTCTGCCTGCTGACCTGGGGAGGCCATTGGCTCTATGGAAAACACTGTGATAACCTCCTAAGGAGAGCAGCCTGTCAAGAAGCTCAGGTGTTTGGCAATCAACTCATTCCTCCCAATGCACAAGTGAAGAAGGCCACTGTTTTTCTCAATCCTGCAGCTTGCAAAGGAAAAGCCAGGACTCTATTTGAAAAAAATGCTGCCCCGATTTTACATTTATCTGGCATGGATGTGACTATTGTTAAGACAGATTATGAGGGACAAGCCAAGAAACTCCTGGAACTGATGGAAAACACGGATGTGATCATTGTTGCAGGAGGAGATGGGACACTGCAGGAGGTTGTTACTGGTGTTCTTCGACGAACAGATGAGGCTACCTTCAGTAAGATTCCCATTGGATTTATCCCACTGGGAGAGACCAGTAGTTTGAGTCATACCCTCTTTGCCGAAAGTGGAAACAAAGTCCAACATATTACTGATGCCACACTTGCCATTGTGAAAGGAGAGACAGTTCCACTTGATGTCTTGCAGATCAAGGGTGAAAAGGAACAGCCTGTATTTGCAATGACCGGCCTTCGATGGGGATCTTTCAGAGATGCTGGCGTCAAAGTTAGCAAGTACTGGTATCTTGGGCCTCTAAAAATCAAAGCAGCCCACTTTTTCAGCACTCTTAAGGAGTGGCCTCAGACTCATCAAGCCTCTATCTCATACACGGGACCTACAGAGAGACCTCCCAATGAACCAGAGGAGACCCCTGTACAAAGGCCTTCTTTGTACAGGAGAATATTACGAAGGCTTGCGTCCTACTGGGCACAACCACAGGATGCCCTTTCCCAAGAGGTGAGCCCGGAGGTCTGGAAAGATGTGCAGCTGTCCACCATTGAACTGTCCATCACAACACGGAATAATCAGCTTGACCCGACAAGCAAAGAAGATTTTCTGAATATCTGCATTGAACCTGACACCATCAGCAAAGGAGACTTTATAACTATAGGAAGTCGAAAGGTGAGAAACCCCAAGCTGCACGTGGAGGGCACGGAGTGTCTCCAAGCCAGCCAGTGCACTTTGCTTATCCCGGAGGGAGCAGGGGGCTCTTTTAGCATTGACAGTGAGGAGTATGAAGCGATGCCTGTGGAGGTGAAACTGCTCCCCAGGAAGCTGCAGTTCTTCTGTGATCCTAGGAAGAGAGAACAGATGCTCACAAGCCCCACCCAGTGAGCAGCAGAAGACAAGCACTCTGAGACCACACTTTAGGCCACCGGTGGGACCAAAAGGGAACAGGTGCCTCAGCCATCCCAACAGTGTCGTCAGAGGGTCCCCAGGGCATTTTCATGGCAAGTACCCCTCTGCCCCCACTCCAGCAGTGCTTCCCAAAGTGTGCTCTGTCACCTGCTTTGCAATCGGCTTCCATTAGCGCATGTTTTATTTTGGTGTGACGGTTGGCCCTCCTAAACACGGACTTTCCTCAGGCTGGTTCAAGACGGAAAAGGACTTTCTTCTGTTTTCTTCCAAAGTGCAACCACAGTGGAGAGCCCACGGTGGGCTTAGCCTGCCTAGGCCCTTCCATTTCTCTTCTTTGACCGTGCTAGGAATTCCAGGAAAGTGCATTCCTGCCCTGGTGACCTTTTCCTATGTCTAGGCTCCTCCACAGGTGCTGCTATTTTGTGAGCTCCGGCTCCTGTTTAGCTTTTATTTCAGTTCTAACCTCAGTCCAGAAACATATGTGAGGTTGTTTCCCTCTTCAGCCACGGCTACAATACCGGAAAATGCTAGTTTTTATTTATTTTTTTAAGTagtgcttcctaaatggtttgcatgagagccacctggggtacatgttgaaaacttatttggggtctaccccaaacctaataacccaaatttggggatggggcccaggaatatgcatttttaaaaagtcatctgcccttcccaggtgattctgTAAGTTGTCCCTCAACTGTACTTGGAGAAATCGTGTTTTAAAGcagtagtccacaaagtattctgctcatgtgcccccaaaagtattttgaaaaatcatgtataccctcacccatctaagttgatatctaaaattttatctaagttggtatctaaaatttttcatgggaagttaaatagttgacaaagtatgtatttgctggtgtcgtgtaaatattggtattttaaaataaaaactgttacatcactattttaaacatatccagtacaatttaaatatcacaacaatttgacacccttcattcatttataaaaataaatgagctagttctttagtagttaaacatttcaaattggcttttctccttctgtatttccataccacttttcagccaagaatcctatcataatgtaatctattatgcccgacatcttttaatcattcaccccattacttcttgtcaacaaaaaatataaatggaaattttttttttagctcttgctttaagtgtttgtttgttatctcagtccagaaccaatattatcgtaattaattattggtatataatgaaaacggtattaattcttggatgattaaaagtttttttattagaatgttctttatcctaattagttcatttatccaagaatacatgaatgtgatttacagctgagatggggttcaacctcagctgtattccttgtttctgtatagatgtaagcacataaattcgatggaatagaattacgttaacaatgtttttacagttctttggattcctttggcattttgacaaagatcacagtgctctatcatcaagaattattaatgatgatctatcaactaacaaacaacttgattagattctcctttagtctgttgaaagcagagaactgaaatccacctgatttaccatggctttgccagccagtcattagcaccatttactttTACTATCGCTGACATTttcctttgttcagtggccctgaggttcttacactctagggggcagtgcaccacaggaagatagatcaatgagggaggattgcgagggggaaggggaggaagcagagctggcaggccttagctacaggctctctctcaggcagatcccttttaagaTACATACACCATGCCCACACATCCCATGGAGAGAGACCAATGCTTTAGTAGATTACAGAACAGCTATGAAAAGTCCATGAATGAAGATCACAAAAAGGAAGGCTTTCTTATTTCATACTGTATTCTTCAGGGTGGTAAAATTTCTGCTTTTGGCAAAAACATAACAGACGGTTCCAAACATCAGCATAAAGATCACTCATCCCATACCACCCACAGGTAGGGAGGAAGGATGCTGTAGTATATGAAAACAAAAGTTTTCACCTGAGCTGAGAGCATTTAGCATATCGTGGTTCTGTAACAATATCAAGGACCAGTGCAGAATCTGGCTTTCTTTTCTGATAGGCTACCAGTGTGTGTTTATGTGTGCTCATTTTGTGGTTCTAATCATAATGGTACATATAATTAGGGAAGGATATGGAAGCCACTTTAGAATCTTATTCATTTTTAAATATAAATATGCCTTGTTTCAAA

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