Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name VDAC1P6
Plot displaying the genomic locations of a retrocopy (in chrY) and its respective parental gene (in chr5). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chrY:5206366-5208078  UCSC
Coordinates (T2T) chrY:4885909-4887621  UCSC
Coordinates (hg19) chrY:5074407-5076119  UCSC
Strand -
Parental Sequence XM_017009822.1
Parental seq. overlap 1471 bp
Parental seq. overlap (%) 75.9%
Genomic Region Intragenic (PCDH11X)
Intragenic (PCDH11Y)
Retrocopy Summary VDAC1P6, located on chrY:5206366-5208078, is a retrocopy of the parental gene VDAC1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name VDAC1
Full Name voltage dependent anion channel 1
Also known as PORIN|VDAC-1
Coordinate chr5:133971871-134070987
Strand -
Gene summary This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.[provided by RefSeq, Sep 2010]

Homology

Species Scientific Name Retrocopy
Gibbon Nomascus leucogenys VDAC1P13
Green monkey Chlorocebus sabaeus VDAC1P13
Rhesus Macaca mulatta VDAC1P13
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>VDAC1P6
CCACCAAAGTGACGGGCAGTCTGGAAACCAAGTACAGATGGACTGAGTACGGCCTGACGTTTACAGAGAAATAGAACACGGATAATACACTAGGCACCGAGATTACTGTGGAAGATCAGCTTGCACGTGGACTGAAGCTGACCTTCGATTCATCCTTCTTACCTAAGACTGGGGGAAAAAAGATGCTAAAATCAAGACAGGTTACAAGCAGGAGCACATTACCCTGGACTGCAACATAGATTTCGACATTGCTGGGCCTTCCATCCGGGCTGCTCTGATGCTGGGTTACAAGGGCTGGCTGGCCGGCTACCAGATGAATTTTGAGACTGCAAAGTCCGGAGTGACCCAGAGCAACTTTGCAGTTGGCTGCAAGACTGATGAATTCCAATTTCACACTAATGTGAATGACGGGACAGAGTTTGGCGGCCTCATTTACCAGAAAGTGAACAAGAAGTTGGAGACTGCTGTCAATCTCACCTGGACAAGCAGGAAACAGTAACACGCATTTCAAAATAGCAGCCAAGTATTTGATTGACCCTGAAGCCTGCTTCTTGGCTAAAGTGAACAACTCCAGCCTGATAGGTTTAGGATACACTCAGACCCTAAAGCCAGGTATCAAACTGACACTGTCAGCTCTTCTGGATGGCAAGAACGTCAATGCTGGTGGCCACAAGCTTGGTCTAGGACTGGAATTTCAAGCATAAATGAATACTGTACAATTGTTTAATTTTAAACTATTTTGCAGCATAGCTACCTTCAGAATTTAGTGTATCTTTTAATGTTGTATGTCTGGGACGCAAGTATTGCTAAATATGTTACCCCTCCAGGTTAAAGATGATTCAGCTTTAAGATGTTACCCTTTCAGAGGTACAGAAGAAACTCATTTCCAAAAAAGGCCCTTTCAGTGGTAGACTTGGGGGAACTTGGCAGCCACTTTGAGATGCCAGGTGTCTTTTTTCTCTAGAAATGGCTGCAAGTGGAAGCTGATAATATGTAGGCGCTTTGTAAGTTCATATTGAGTAAATGAATGAAATTGTGATTTCCTGAGAATCGAACCTTGGTTTCCTAACCCTAACTGATGAGGGGCTTGCTGCTTGATGGTGTGTACAAACTCACCTGAATGGGACTCTTTTAGACAGAGCTTCATGACCTTTTCCCAGCCCAGTTCATCGTTACCTCTTTTACACCAAAAGGTCTGCAGGGTGTGGTCACTCTTTCTTTTGTGCCATTTTGGGGTGGAGAGGGTGGATGTGATGAAGCCAATAATTCAGGACTTATTCCTTCCTGTGTTGTGTTTTTTAGCCCTTGCACTAGAGTATGAAATAGCTTCCAGGAACTCCAGCTATAAGCTTGGAAGCGTCTGTGTGATTGTAATCACATGGTGACAACACTCAGAATCTAAATTGGACTTCTGTTATATTCTCACCCTTCAATTTGTTTTTTAGCAGTCTAATGGGTACATTTTAGAGTCTTCCATTTTCTGTGGAATTAGATCCTCCCCTTCAAATGCTGTAATTAACATCACTTAAACTTGAATAAAATATTGAAACCTaAAGCATAAGATGGCTGTGCCACCCATGTATGCCAATCTTGGCAAGTCTGCCAGGGATGTCTTCACTAAGGGCTATg
>XM_017009822.1
GGGATGGTGACGCTTGGACCGGTTTCCTGTGAAAATCCTACGAGCcattttggcaataaatttgtacaagttctttaaaactgtgcagacctctgatccagcacctccttgctgcctagaaaataatcgcagatacgtgcaaaaagCAGAAGATGGCTGTGCCACCCACGTATGCCGATCTTGGCAAATCTGCCAGGGATGTCTTCACCAAGGGCTATGGATTTGGCTTAATAAAGCTTGATTTGAAAACAAAATCTGAGAATGGATTGGAATTTACAAGCTCAGGCTCAGCCAACACTGAGACCACCAAAGTGACGGGCAGTCTGGAAACCAAGTACAGATGGACTGAGTACGGCCTGACGTTTACAGAGAAATGGAATACCGACAATACACTAGGCACCGAGATTACTGTGGAAGATCAGCTTGCACGTGGACTGAAGCTGACCTTCGATTCATCCTTCTCACCTAACACTGGGAAAAAAAATGCTAAAATCAAGACAGGGTACAAGCGGGAGCACATTAACCTGGGCTGCGACATGGATTTCGACATTGCTGGGCCTTCCATCCGGGGTGCTCTGGTGCTAGGTTACGAGGGCTGGCTGGCCGGCTACCAGATGAATTTTGAGACTGCAAAATCCCGAGTGACCCAGAGCAACTTTGCAGTTGGCTACAAGACTGATGAATTCCAGCTTCACACTAATGTGAATGACGGGACAGAGTTTGGCGGCTCCATTTACCAGAAAGTGAACAAGAAGTTGGAGACCGCTGTCAATCTTGCCTGGACAGCAGGAAACAGTAACACGCGCTTCGGAATAGCAGCCAAGTATCAGATTGACCCTGACGCCTGCTTCTCGGCTAAAGTGAACAACTCCAGCCTGATAGGTTTAGGATACACTCAGACTCTAAAGCCAGGTATTAAACTGACACTGTCAGCTCTTCTGGATGGCAAGAACGTCAATGCTGGTGGCCACAAGCTTGGTCTAGGACTGGAATTTCAAGCATAAATGAATACTGTACAATTGTTTAATTTTAAACTATTTTGCAGCATAGCTACCTTCAGAATTTAGTGTATCTTTTAATGTTGTATGTCTGGGATGCAAGTATTGCTAAATATGTTAGCCCTCCAGGTTAAAGTTGATTCAGCTTTAAGATGTTACCCTTCCAGAGGTACAGAAGAAACCTATTTCCAAAAAAGGTCCTTTCAGTGGTAGACTCGGGGAGAACTTGGTGGCCCCTTTGAGATGCCAGGTTTCTTTTTTATCTAGAAATGGCTGCAAGTGGAAGCGGATAATATGTAGGCACTTTGTAAATTCATATTGAGTAAATGAATGAAATTGTGATTTCCTGAGAATCGAACCTTGGTTCCCTAACCCTAATTGATGAGAGGCTCGCTGCTTGATGGTGTGTACAAACTCACCTGAATGGGACTTTTTTAGACAGATCTTCATGACCTGTTCCCACCCCAGTTCATCATCATCTCTTTTACACCAAAAGGTCTGCAGGGTGTGGTAACTGTTTCTTTTGTGCCATTTTGGGGTGGAGAAGGTGGATGTGATGAAGCCAATAATTCAGGACTTATTCCTTCTTGTGTTGTGTTTTTTTTTGGCCCTTGCACCAGAGTATGAAATAGCTTCCAGGAGCTCCAGCTATAAGCTTGGAAGTGTCTGTGTGATTGTAATCACATGGTGACAACACTCAGAATCTAAATTGGACTTCTGTTGTATTCTCACCACTCAATTTGTTTTTTAGCAGTTTAATGGGTACATTTTAGAGTCTTCCATTTTGTTGGAATTAGATCCTCCCCTTCAAATGCTGTAATTAACAACACTTAAAAAACTTGAATAAAATATTGAAACCTCA

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