Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name GAPDHP11
Plot displaying the genomic locations of a retrocopy (in chr2B) and its respective parental gene (in chr12). Each line represents a retrocopy.
Species Pan troglodytes
Coordinates chr2B:73982812-73983307  UCSC
Strand +
Parental Sequence XM_508955.7
Parental seq. overlap 450 bp
Parental seq. overlap (%) 32.7%
Genomic Region Intragenic (CALCRL)
Retrocopy Summary GAPDHP11, located on chr2B:73982812-73983307, is a retrocopy of the parental gene GAPDH. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name GAPDH
Full Name glyceraldehyde-3-phosphate dehydrogenase
Also known as GAPD
Coordinate chr12:6735763-6739722
Strand +
Gene summary N/A

Homology

Species Scientific Name Retrocopy
Human Homo sapiens GAPDHP59
Bonobo Pan paniscus GAPDHP12
Gorilla Gorilla gorilla GAPDHP11
Orangutan Pongo abelii GAPDHP11
Gibbon Nomascus leucogenys GAPDHP43
Green monkey Chlorocebus sabaeus GAPDHP16
Crab-eating macaque Macaca fascicularis GAPDHP41
Rhesus Macaca mulatta GAPDHP39
Baboon Papio anubis GAPDHP35
Golden snub-nosed monkey Rhinopithecus roxellana GAPDHP48
Marmoset Callithrix jacchus GAPDHP32
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>GAPDHP11
TCTGCCAATGTGTCAGTGGTGGACCTGACCTGCCGTCTGGAAAAACCTGCCAATTATGATGACATCAAGAAGGTGGTGAACCAGGCATCGGAGGGCCCCCTCAAGGACATTCTGGGCTACACTGAGCACCAGGTTGTCTCCTCCGACTTCAACAGTGACACCCACTCTTCCACCTTCAGTGAGGGGGCTGGCATTGCTCTCAACGACCACTTTGTCAAGCTCATTTCCTTGTATGACAATGAATTTGGCTACACCAACAGGGTGGTGGATCATGGTCCACATGGCCTCCAGAAAGTAAGACCCCTGGACCACCAGCCCCAGCAAGAGCACGAGAGGAAGAGAGAGGCCCTCATTGCTGGAGAGTCCCTGCCACACTCAGTCTCCCACCACACTAAGAATCTCCCCTCTTCACAGTTTCCATGCAGACCCCCTGAAGACGGAGGGGCCTAGGGAACCTGACCTCGTCATGTACCATCAACAAAGTCCCTTGTGCTCA
>XM_508955.7
CTGGCTGAGCCTGGCGGGAGGCGGGGTCCGAGTCACCGCCTGCCGCCGCGCCCCCGGTTTCTATAAATTGAGCCCGCAGCCTCCCGCTTCGCTCTCTGCTCCTCCTGTTCGACAGTCAGCTGCATCTTCTTTTGCATTGCCAGCCGAGCCACATCGCTGAGACACCATGGGGAAGGTGAAGGTCGGAGTCAACGGATTTGGTCGTATTGGGCGCCTGGTCACCAGGGCTGCTTTTAACTCTGGTAAAGTGGATATTGTTGCCATCAATGACCCCTTCATTGACCTCAACTACATGGTTTACATGTTCCAATATGATTCCACCCATGGCAAATTCCATGGCACCGTCAAGGCTGAGAACGGGAAGCTTGTCATCAATGGAAATCCCATCACCATCTTCCAGGAGCGAGATCCCTCCAAAATCAAGTGGGGCGATGCTGGCGCTGAGTACGTCGTGGAGTCCACTGGCGTCTTCACCACCATGGAGAAGGCTGGGGCTCATTTGCAGGGGGGAGCCAAAAGGGTCATCATCTCTGCCCCCTCTGCTGACGCCCCCATGTTCGTCATGGGTGTGAACCATGAGAAGTATGACAACAGCCTCAAGATCATCAGCAATGCCTCCTGCACCACCAACTGCTTAGCACCCCTGGCCAAGGTCATCCATGACAACTTCGGTATCGTGGAAGGACTCATGACCACGGTCCATGCCATCACTGCCACCCAGAAGACTGTGGATGGCCCCTCCGGGAAACTGTGGCGTGATGGCCGCGGGGCTCTCCAGAACATCATCCCTGCCTCTACTGGCGCTGCCAAGGCTGTGGGCAAGGTCATCCCTGAGCTGAACGGGAAGCTCACTGGCATGGCCTTCCGTGTCCCCACTGCCAACGTGTCAGTGGTGGACCTGACCTGCCGTCTAGAAAAACCTGCCAAATATGATGACATCAAGAAGGTGGTGAAGCAGGCGTCGGAGGGCCCCCTCAAGGGCATCCTGGGCTACACTGAGCACCAGGTGGTCTCCTCTGACTTCAACAGCGACACCCACTCCTCCACCTTCGACGCTGGGGCTGGCATTGCCCTCAACGACCACTTTGTCAAGCTCATTTCCTGGTATGACAACGAATTTGGCTACAGCAACAGGGTGGTGGACCTCATGGCCCACATGGCCTCCAAGGAGTAAGACCCCTGGACCACCAGCCCCAGCAAGAGCACAAGAGGAAGAGAGAGACCCTCACTGCTGGGGAGTCCCTGCCACACTCAGTCCCCCACCACACTGAATCTCCCCTCCTCACAGTTTCCATGTAGACTCCTTGAAGAGGGGAGGCGCCTAGGGAGCCGCACCTTGTCGTGTACCATCAATAAAGTACCCTGTGCTCAACCA

Publications

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