Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name FHP2
Plot displaying the genomic locations of a retrocopy (in chr17) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Macaca fascicularis
Coordinates chr17:21449314-21450026  UCSC
Strand +
Parental Sequence NM_001285175.1
Parental seq. overlap 672 bp
Parental seq. overlap (%) 41.8%
Genomic Region Intergenic
Retrocopy Summary FHP2, located on chr17:21449314-21450026, is a retrocopy of the parental gene FH. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name FH
Full Name N/A
Also known as Fumarase
Coordinate chr1:7937258-7959689
Strand +
Gene summary N/A

Homology

Species Scientific Name Retrocopy
Human Homo sapiens FHP1
Chimpanzee Pan troglodytes FHP2
Bonobo Pan paniscus FHP2
Gorilla Gorilla gorilla FHP1
Orangutan Pongo abelii FHP2
Gibbon Nomascus leucogenys FHP1
Green monkey Chlorocebus sabaeus FHP1
Rhesus Macaca mulatta FHP2
Baboon Papio anubis FHP2
Golden snub-nosed monkey Rhinopithecus roxellana FHP4
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>FHP2
ACAGAAAAGGTTGCTGCAAAAGTGACGCACGTACAGGCTTGCCTTTTGTCACTGCTCCAAATAAATTTGAAGTTCTGGCTGCTCATGACGCTCTGGTTGAGCCCAGTGGATTCATGAACACTACTGCCTGCAGTCTGATGACGATAGCAAATAATACTCGTTTTCTGGGTTCTGGTCCTCGGTCAGGTCTGGGAGAACTGATCATGCCTGAAAATGAACCAGGAAGTAGTATCATGCCAGGCAAGGTGAACCCTACTCAGTGTGAAGCAATGACCGTGGTTGCAGCCCGAGTCATGGGGAATCGTGTTGCTGTAACAGTTGGAGGCAGCAATGGACATTTTGAGTTGAATGTTTTCAAGCCAATGATGATTTAAAATGTGTTACACTCAGCCAGGCTGCTGGGGGATGCTTCAGTTTCCTTTACAGAAAACTGCGTGGTGGGAATCCAGGCCAGGACAGAAAGGATCAACAAGCTGGTGAATGAGTCTCAAATGTTGGTGACAGCTCTCAGTCCTCATATAGGGTATGACAAGGCAGCAAAGATTGCTAAGACAGCACACAAAAATGGATCAACCTTAAAGGAAACTGCTATTGAACTTGGCTATCTCACAGCAGAACAGTTTGATGAATGGGTAAAAACTAAGGACATGCTGAGTCCAAAATGATATAAATAAACTTGTAATGAAAATAAATGTGTACAAAATTTTAAAAAA
>NM_001285175.1
GAACTTCTACCCAGGCTGCCTCAGCACCATGTACCGAGCACTCTGGCTCCTCGCGCGCTCGCGTCGCCTTGTGCGGCCTCCAGCCTCAGCCTCAGCTTCGGCTCCCGGCTTGAGTGGCGCTGCCGTGCCCTCGTTTTGGCCCCCGAACGCGGCTCGAATGGCTAGCCAAAATTCCTTCCGGATAGAATATGATACCTTTGGTGAACTAAAGGTGCCAAATGATAAGTATTACGGCGCGCAAACCGTGAGATCTACGATGAACTTTAAGATTGGAGGTGTGACAGAACGCATGCCAACCCCAGTTATTAAAGCTTTTGGCATCTTGAAGCGAGCGGCTGCTGAAGTAAACCAGGATTATGGTCTTGATCCAAAGATTGCTAATGCAATCATGAAGGCAGCAGACGAGGTAGCTGAAGGTAAATTAAATGATCATTTTCCTCTCGTGGTATGGCAGACTGGATCAGGAACTCAGACAAATATGAATGTAAATGAAGTCATTAGCAATAGGGCAATTGAAATGTTAGGAGGTGAACTTGGCAGCAAGATACCTGTGCATCCCAATGATCATGTTAATAAAAGCCAGAGCTCAAATGATACTTTTCCCACAGCAATGCACATTGCTGCTGCAATAGAAGTTCATGAAGTACTGTTACCAGGACTGCAGAAGTTACATGATGCTCTTGATGCCAAATCCAAAGAGTTTGCGCAGATCATCAAGATTGGACGTACTCATACTCAGGATGCTGTTCCACTTACTCTTGGGCAGGAATTTAGTGGTTATGTTCAACAAGTAAAATATGCAGTGACAAGAATAAAAGCTGCCATGCCAAGAATCTATGAGCTCGCAGCTGGAGGCACTGCTGTTGGTACAGGTTTAAATACTAGAATTGGCTTTGCAGAAAAGGTTGCTGCAAAAGTGGCTGCACTTACAGGCTTGCCTTTTGTCACTGCTCCAAATAAATTTGAAGCTCTGGCTGCTCATGATGCTCTGGTTGAGCTCAGTGGAGCCATGAACACTACTGCCTGCAGTCTGATGAAGATAGCAAATGATATTCGTTTTCTGGGCTCTGGTCCTCGGTCAGGTCTGGGAGAACTGATCTTGCCTGAAAATGAACCAGGAAGCagtatcatgccagGCAAGGTGAACCCTACTCAGTGTGAAGCAATGACCATGGTTGCAGCCCAGGTCATGGGGAACCATGTTGCTGTCACTGTCGGAGGCAGCAATGGACATTTTGAGTTGAATGTTTTCAAGCCAATGATGATTAAAAATGTGTTACACTCAGCCAGGCTGCTGGGGGATGCTTCAGTTTCCTTTACAGAAAACTGCGTGGTGGGAATCCAGGCCAATACAGAAAGGATCAACAAGCTGATGAATGAGTCTCTAATGTTGGTGACAGCTCTCAATCCTCATATAGGGTATGACAAGGCAGCAAAGATTGCTAAGACAGCACACAAAAATGGATCAACCTTAAAGGAAACTGCTATTGAACTTGGCTATCTCACAGCAGAGCAGTTTGACGAATGGGTAAAACCTAAGGACATGCTGGGTCCAAAGTGATCTAAATAAATTTATAATGAAAATAAACATGTATACAATTTAAAAAAA

Publications

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