Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name HIGD2AP3
Plot displaying the genomic locations of a retrocopy (in chr15) and its respective parental gene (in chr5). Each line represents a retrocopy.
Species Pan troglodytes
Coordinates chr15:51084656-51085250  UCSC
Strand -
Parental Sequence XM_009450193.3
Parental seq. overlap 534 bp
Parental seq. overlap (%) 60.3%
Genomic Region Intergenic
Retrocopy Summary HIGD2AP3, located on chr15:51084656-51085250, is a retrocopy of the parental gene HIGD2A. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name HIGD2A
Full Name HIG1 hypoxia inducible domain family member 2A
Also known as -
Coordinate chr5:154492463-154493703
Strand +
Gene summary N/A

Homology

Species Scientific Name Retrocopy
Human Homo sapiens HIGD2AP3
Bonobo Pan paniscus HIGD2AP3
Orangutan Pongo abelii HIGD2AP3
Gibbon Nomascus leucogenys HIGD2AP2
Green monkey Chlorocebus sabaeus HIGD2AP2
Crab-eating macaque Macaca fascicularis HIGD2AP1
Rhesus Macaca mulatta HIGD2AP2
Golden snub-nosed monkey Rhinopithecus roxellana HIGD2AP2
Gorilla Gorilla gorilla Without Homology
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>HIGD2AP3
GATTTTCTCCTGCAGCTGTGGCCTAGGCATGGCGACTCCCGGCTTTGTGACTCCGGAGGCCCCCTTTGAATCATCAAAGCCCCCCATCTTTGAGGGGCTTAGCCCCACTGTTTACAGCAATCCAGAGGGTTTCAAGGAAAAGTTCCTTCGCAAGACCCGCGAGAATCCGGTGGTACCCATAGGTTTCCTGTGCACGGCGGCCGTCCTCACCAACGGCCTCTACTGCTTCCACCAGGGCAACAGCCAATGTTCACGGCTTATGATGCACACCCAGATCGCCGCCCAGGGCTTCACTGTTGCAGCCATCTTGCTGGGTCTAGCTGCCACCGCTATGAAGTCTCCACCCTGAGCCCAGGGTCTTGAAAACTCTGCAGAAATCATTCCAAAACCCAGGAGCAACCACTGGCCCTACTATGGGACTTACTCTCTCCTCTCCTTTGAGAGGTCCCTGTGTCGTTGGGGGAGGAAGTGACCCTTCCTGTAACCGTAACTGAAAGATTTTTTCAAAAATCCCAGATTCTGTTGTTTGAATGTTACATACTTCTATTTATGCCACATCTTCCCTCCACTCCCCTGCTTAATAAACTCTAAAAAG
>XM_009450193.3
TTGGCCTTGGGCATCGCGCTGACCACCGCACCAGCAGCTCAAACACGCTGCCTCTCTCTCTCAGACCTCGTGTAACAAACTCCTTCCGGAAGGCGTGCACAAGGCTTTGCGGGCATTTGGGGAAATGTAGTCCTTTTGTAGCACTACCGTGCTGAGCACTACGACTCCCAGGATGCAACGAGCACTTGCGCCTGCGTACAAGGCTCAATCTATTCGTTTCCCCGCCCCTTTCATGACCTTCACCGGGAGGCTGAGCTCGGAGTCCCGATTTTCTCCTGCTGCTGTGGTCCGGACATGGCGACTCCCGGCCCTGTGATTCAGGAGGTCCCCTTTGAACCATCGAAGCCTCCAGTCATTGAGGGGCTTAGCCCCACTGTTTACAGGAATCCAGAGAGTTTCAAGGAAAAGTTCGTTCGCAAGACCCGCGAGAACCCGGTGGTACCCATAGGTTGCCTGGCCACGGCGGCCGCCCTCACCTACGGCCTCTACTCCTTCCACCGGGGCAACAGCCAGCGCTCTCAGCTCATGATGCGCACCCGGATCGCCGCCCAGGGTTTCACGGTCGCAGCCATCTTGCTGGGTCTAGCTGTCACCGCTATGAAGTCTCGACCCTAAGCCCAGGGTCTGGCCTTGAAAGCTCCGCAGAAATGATTGCAAAACCCAGGGAGCAACCACTGGCCCTACCGTGGGACTTACTCCCTCCTCTCCTTTGAGAGGCCCATGTGTCGCTGGGGGAGGAAGTGACCCTTTGGGTAACTGTAACTGAAAGTTTTTTCAAAAATCCTAGATGCTGTTGTTTGAATGTTACATACTTCTATTTGTGCCACATCTCCCCTCCACTCCCCTGCTTAATAAACTCTAAAAATCCACTTGTATTTAATTCA

Publications

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