Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TUBA1AP2
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr12). Each line represents a retrocopy.
Species Pan troglodytes
Coordinates chrX:110856686-110858558  UCSC
Strand -
Parental Sequence NM_001098544.1
Parental seq. overlap 1209 bp
Parental seq. overlap (%) 72%
Genomic Region Intergenic
Retrocopy Summary TUBA1AP2, located on chrX:110856686-110858558, is a retrocopy of the parental gene TUBA1A. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TUBA1A
Full Name tubulin alpha 1a
Also known as TUBA3
Coordinate chr12:39907947-39912239
Strand +
Gene summary N/A

Homology

Species Scientific Name Retrocopy
Human Homo sapiens TUBAP6
Bonobo Pan paniscus LOC100993058P2
Gorilla Gorilla gorilla TUBA1CP3
Orangutan Pongo abelii TUBA1AP2
Gibbon Nomascus leucogenys LOC100585634P2
Green monkey Chlorocebus sabaeus TUBA1AP2
Crab-eating macaque Macaca fascicularis TUBA1AP2
Rhesus Macaca mulatta TUBA1AP2
Baboon Papio anubis LOC101018365P7
Golden snub-nosed monkey Rhinopithecus roxellana LOC104679721P2
Marmoset Callithrix jacchus LOC100392817P6
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TUBA1AP2
GCAGTGTTTGTAGACCTGGAACCCATGGTCATTGACGAAGTTTGCTCTGGCACATACCGTAAGCTCTTCCAACCTGAGCATATCATCACGGGCAAGGAAGATGCTGCCAATAATTATGCCCGAGGGCACTACACCATTGGCAAGGAGATAATTGACTTCATGTTGGGCCAAATTCATAAACTGGCCAACTTGTGCACAGGCCTTCGGGGCTTCTTGGTTTTCACAGCTTTGGCAGGGGAACTGGTTCTGGGTTCACCTCCCTGCTCATGGAATGTCTCTCTGTTGACTATGGTAAGAAATCCGAGCTGGAGTTCTCCATTTACCCAGCTCCTCAGGTTTCCATACCTGTACTAGAGCCCTACAACTCCGCTCTCACCACCCACATCACCCTGGAGCACTCCGATTGTGCTTTCATGATAGACAGTGAGGCCATTTAGGGCATCTGTTATAGAAACCTTGATATTAAGCCCCCAACCTACACTAACCTAAATAGGTTCATAGGTCAAATTGTGTCCTCTGTCACTGCTTCCCTGAGATTTGATGGAACCCTAAATATTGATCTGACAGAACTCCAGACCAACCTGGTGTCCTATCCCTGCATCCACTTCTCTCTGGGCAACTATGCCCTCtCCCTCATCATCTCTACTGGGAAAGCCTACCATAGACAGCTTTCTGTAGCAGAGATTACCAATGCTTTCTTTGAGCAAGCCAGCCAGGTGGTGAAACATGACCCTTACTATGGTAAATACATGGCTTGCTGCTTGTTGTACCATAAAGATGTGGTTCCCAAAGATGTCAGTGCTGCCATTGCCACCATCAAGACTGAGCGTACCATACAGTCTGTGGATTGGTGCCCCACTGGCTTCAAGATGGCATTAATTACTAGCCTCCCACTGTGGTGCCTGGCAGAGACCTGACTGAGATACAGAGAGCTGTGTGCATGTTGGGCAACAACACAGCCATTGCTGAGACCTGGGCTCACCTGGACCACAAGTTTGACCTGATGTATTCCAAGCACGTCTTTGTTCATTGGTAAGTGGGTAAGGAAATGGAGGAAGGAGAGTTTTCTGAGGTCCGTGAGGACATGGCTGCCCTTGAGAAGGATTATGAGGATGTTGGTGTGGAGTCTGTTGAAAAAGAGGGTGAAGAAGAAGAATACTAAAGTTAAAACACCAGCACAGATGCTGCTTTCACAGGGAAGCTTATTCTGTTTTAAACATTGAAAAATTGTGGTCTGATGAGTTAATTTGTATGCAGCAGTGTATGTATATGCTCTCATATACAATTACTGACTTAGGCTTTAAAACATGTATGCTGTATTACAGACTCAAGCTGTTCATTTCTGTGACGGGTTTTAAATAAAGTATTGCCTGTCTTT
>NM_001098544.1
AGGTTCTCTTACATCGACCGCCTAAGAGTCGCGCTGTAAGAAGCAACAACCTCTCCTCTTCGTCTCCGCCATCAGCTCGGCAGTCGCGAAGCAGCAACCATGCGTGAGTGCATCTCCATCCACGTTGGCCAGGCTGGTGTCCAGATTGGCAATGCCTGCTGGGAGCTCTACTGCCTGGAACACGGCATCCAGCCCGATGGCCAGATGCCAAGTGACAAGACCATTGGGGGAGGAGATGATTCCTTCAACACCTTCTTCAGTGAGACGGGTGCTGGCAAGCATGTGCCCCGGGCAGTGTTTGTAGACTTGGAACCCACAGTCATTGATGAAGTTCGCACTGGCACCTACCGCCAGCTCTTCCACCCTGAGCAACTCATCACAGGCAAGGAAGATGCTGCCAATAACTATGCCCGAGGGCACTACACCATTGGCAAGGAGATCATTGACCTCGTGTTGGACCGAATTCGCAAGCTGGCCGACCAGTGCACGGGTCTCCAGGGCTTCTTGGTTTTCCACAGCTTTGGTGGGGGAACTGGTTCTGGGTTCACCTCCCTGCTCATGGAACGTCTCTCAGTTGATTATGGCAAGAAGTCCAAGCTGGAGTTCTCCATTTACCCGGCGCCCCAGGTTTCCACAGCTGTAGTTGAGCCCTACAACTCCATCCTCACCACCCACACCACCCTGGAGCACTCTGATTGTGCCTTCATGGTAGACAATGAGGCCATCTATGACATCTGTCGTAGAAACCTTGATATTGAGCGTCCAACCTATACTAACCTGAATAGGTTAATAGGTCAAATTGTGTCCTCCATCACTGCTTCCCTGAGATTTGATGGAGCCCTGAATGTTGACCTGACAGAATTCCAGACCAACCTGGTGCCCTATCCCCGCATCCACTTCCCTCTGGCCACATATGCCCCTGTCATCTCTGCCGAGAAAGCCTACCATGAACAGCTTTCTGTAGCAGAGATCACCAATGCTTGCTTTGAGCCAGCCAACCAGATGGTGAAATGTGACCCTCGCCATGGTAAATACATGGCTTGCTGCCTGTTGTACCGTGGTGACGTGGTTCCCAAAGATGTCAATGCTGCCATTGCCACCATCAAGACCAAGCGTACCATCCAGTTTGTGGATTGGTGCCCCACTGGCTTCAAGGTTGGCATCAACTACCAGCCTCCCACTGTGGTGCCTGGTGGAGACCTGGCCAAGGTACAGAGAGCTGTGTGCATGCTGAGCAACACCACAGCCATTGCTGAGGCCTGGGCTCGCCTGGACCACAAGTTTGACCTGATGTATGCCAAGCGTGCCTTTGTTCACTGGTACGTGGGTGAGGGGATGGAGGAAGGCGAGTTTTCAGAGGCCCGTGAGGACATGGCTGCCCTTGAGAAGGATTATGAGGAGGTTGGTGTGGATTCTGTTGAAGGAGAGGGTGAGGAAGAAGGAGAGGAATACTAAAGTTAAAATGTCACAAAGGTGCTGCTTTTACAGGGAAGCTTATTCTGTTTTAAACATTGAAAAGTTGTGGTCTGATCAGTTAATTTGTATGTAGCAGTGTATGCTCTCATATACAATTACTGACCTATGCTTTAAAACATGAATGCTTTGTTACAGACCCAAGCTGTCCATTTCTGTCATGGGTTTTGAATAAAGTATTCCCTGTCTTAAA

Publications

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