Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PHBP13
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr5). Each line represents a retrocopy.
Species Gorilla gorilla
Coordinates chr12:36802018-36802965  UCSC
Strand +
Parental Sequence XM_019027640.2
Parental seq. overlap 868 bp
Parental seq. overlap (%) 46.5%
Genomic Region Intergenic
Retrocopy Summary PHBP13, located on chr12:36802018-36802965, is a retrocopy of the parental gene PHB. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PHB
Full Name N/A
Also known as PHB
Coordinate chr5:32403581-32414443
Strand +
Gene summary N/A

Homology

Species Scientific Name Retrocopy
Human Homo sapiens PHBP18
Chimpanzee Pan troglodytes PHBP13
Bonobo Pan paniscus PHBP12
Orangutan Pongo abelii PHBP13
Gibbon Nomascus leucogenys PHBP8
Green monkey Chlorocebus sabaeus PHBP8
Crab-eating macaque Macaca fascicularis PHBP9
Rhesus Macaca mulatta PHBP10
Baboon Papio anubis PHBP9
Golden snub-nosed monkey Rhinopithecus roxellana PHBP11
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PHBP13
GGTGGCTGGGGAATTCATGTGTAGATCAGAGTGGAAGCAGGTGTGAGAGGGTCCAGCAGAAGAAAACATGGCAGCCAAAGTGTTTGAGTCCATCGGCAAGTTTGGCCCGGCCTTAGCTGTTGCAGGAGGCGTGGTGAACTCCACCTTATATAATGTGTATGCTGGGCGGCAGAGCTGTCATCTTTGACCGATTCCGTGGAGTACAGGACATTGTGGTGGGGGAAGAGACTCACTTTCTCATCCCATGGGTACAGAAACCAATTATCTTTGACTGCCATTCTCCACCTCGTAATGTACCAGTCATCACTGGTAGCAAAGATTTACAGAATGTCAACATCACACTGCGCATCGTCTTCCGGCCCATCGTTAGCCAGCTTCCTCGCATCTTCAGCATCGGAGACGACTATGACGAGCGTGTGCTGACGTCCATCACGACCAAGGTCCTCAAGTCAGTGGTGGCTAGCTTCGATGCTGGAGAAGTAATCACCCAGAGAGAGTTGGTCTCCAGGCAGGTGAACAACGACCTTACGGAGCAAGCAGCCACCTTTGGGCTCATCCTGGACGACGTGTCCTTGACACATCTGACCTTCGGGAAGGAATTCACAGAAGCGTTATAAGCCAAACAGGTGGCTCAGCAGGAAGCAGAGAGGGCCAGATCTGTGGTGGAAACGGCTGAGCAGCAGAAAAAGGCAGCCATCATCTCTGCTGCGGGCGACTCCAAGGCAGCCGAGCTGATTGATTGCCAACTCACTGGCCACCGCAGGAGACGGCCTGAGCTGCCCAAGCTGGAAGCTGCGGAGGACATCGCGTAACAGCTCTCACGCTCTCAGAGCATGATCTACCTGCTGGCGGGGCAGACCGTGCTCCTCTGGCTGCTCCAGTGAGGGCCTGCCCACTCTGCCTGCACCTCCGCGGGCCAATTGAGCCATAGCCCCGATGATTCTTAAC
>XM_019027640.2
GGGCGGGGCAGAGGAGCGCATGCGCAGTATGTGTGGTTGGGGAATTCATGTGGAGGTCAGAGTGGAAGCAGGTGTGAGAGGGTCCAGCAGAAGGAAACATGGCTGCCAAAGTGTTTGAGTCCATTGGCAAGTTTGGCCTGGCCTTAGCTGTTGCAGGAGGCGTGGTGAACTCTGCCTTATATAATGTGGATGCTGGGCACAGAGCTGTCATCTTTGACCGATTCCGTGGAGTGCAGGACATTGTGGTAGGGGAAGGGACTCATTTTCTCATCCCATGGGTACAGAAACCAATTATCTTTGACTGCCGTTCTCGACCACGTAATGTGCCAGTCATCACTGGTAGCAAAGATTTACAGAATGTCAACATCACACTGCGCATCCTCTTCCGGCCCGTTGCCAGCCAGCTTCCTCGCATCTTCACCAGCATCGGAGAGGACTATGATGAGCGTGTGCTGCCGTCCATCACAACCGAGATCCTCAAGTCAGTGGTGGCTCGCTTTGATGCTGGAGAACTAATCACCCAGAGAGAGCTGGTCTCCAGGCAGGTGAGCGACGACCTTACGGAGCGAGCCGCCACCTTTGGGCTCATCCTGGATGACGTGTCCTTGACACATCTGACCTTCGGGAAGGAGTTCACAGAAGCGGTGGAAGCCAAACAGGTGGCTCAGCAGGAAGCAGAGAGGGCCAGATTTGTGGTGGAAAAGGCTGAGCAACAGAAAAAGGCGGCCATCATCTCTGCTGAGGGCGACTCCAAGGCAGCTGAGCTGATTGCCAACTCACTGGCCACTGCAGGGGATGGCCTGATCGAGCTGCGCAAGCTGGAAGCTGCAGAGGACATCGCGTACCAGCTCTCACGCTCTCGGAACATCACCTACCTGCCGGCGGGGCAGTCCGTGCTCCTCCAGCTGCCCCAGTGAGGGCCCACCCTGCCTGCACCTCCGCGGGCTGACTGGGCCACAGCCCCGATGATTCTTAACGCAGCCTTCCTTCTGCCCCCACCCCAGAAATCACTGTGAAATTTCATGATTGGCTTAAAGTGAAGGAAATAAAGGTAAAATCACTTCAGATCTCTAATTAGTCTATCAAATGAAACTCTTTCATTCTTCTCATATCCATCTACTTTTTTATCCACCTCCCCTACCAAAAATTGCCAAGTGCCTATGCAAACCAGCTTTAGGTCCCAATTCGGGGCCTGCTGGAGTTCCGGCCTGGGCACCAGCATTTGGCAGCACGCAGGCGGGGCAGTGTGTGATGGACTGGGAAGCACAGGTGTCTGCCTAGGTCCACGTGTGGCCTCCGTCCTGTCACTGATGGAAGATTTGCGGATGAGGGCATGTGCGGCTGAACTGAGAAGGCAGGCCTCCGTCTTCCCAGCAGTTCCTGCGCAGGTGCCGCTGAAGAGAGGTGCCGGGGAGGGGCAGAGAGGAAGTGGTCTGTCTGTTACCATAAGTCTGATTCTCTTTAACTGTGCGACCAGCGGAAACAGGTGTGTGTGAACTGGGCACAGATTGAAGAATCTGCCCCTGTTGAGGTGGGTGGGCCTGACTGTTGCCCCCCAGGGTCCTAAAACTTGGATGGACTTGTATAGTGAGAGAGGAGGCCTGGACCAAGATGTGAGTCCTGTTGAAGACTTCCTCTCTACCCCCCACCTTGGTGCCTCTCAGATACCCAGTGGAATTCCAACTTGAAGGATTGCATCCTGCTGGGGCTGAACATGCCTGCCAAAGATGTGTCCGACCTACATTCCTGGCCCCCTCGTTCAGAGACTGCCCTGCTCACGGGCTCTATGCCTGCCCTGGGAAGGAAACAAATGTGTATAAACTGCTGTCAATAAATGACACCCAGACCTTCCGGCTCA

Publications

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