Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name METTL21AP2
Plot displaying the genomic locations of a retrocopy (in chr25) and its respective parental gene (in chr22a). Each line represents a retrocopy.
Species Nomascus leucogenys
Coordinates chr25:24481656-24482405  UCSC
Strand -
Parental Sequence XM_030802423.1
Parental seq. overlap 650 bp
Parental seq. overlap (%) 59.7%
Genomic Region Intragenic (BRWD1)
Retrocopy Summary METTL21AP2, located on chr25:24481656-24482405, is a retrocopy of the parental gene METTL21A. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name METTL21A
Full Name N/A
Also known as METTL21A
Coordinate chr22a:108137301-108182631
Strand -
Gene summary N/A

Homology

Species Scientific Name Retrocopy
Human Homo sapiens METTL21AP1
Chimpanzee Pan troglodytes METTL21AP1
Bonobo Pan paniscus METTL21AP1
Gorilla Gorilla gorilla METTL21AP1
Orangutan Pongo abelii METTL21AP1
Green monkey Chlorocebus sabaeus METTL21AP1
Crab-eating macaque Macaca fascicularis METTL21AP1
Rhesus Macaca mulatta METTL21AP1
Baboon Papio anubis METTL21AP1
Golden snub-nosed monkey Rhinopithecus roxellana METTL21AP1
Marmoset Callithrix jacchus METTL21AP1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>METTL21AP2
TCAAACCGTTAACATCCAGTCTAAGTGCAGGTCGGATCAGAGGGCTGGGTGCGGGCAGATTGGCCCTGTTGCCCTATGAGGAGACTGTGGGATTGGGGTTGCAGAAATTCCACAAGCCTCTTGCCACCTTTGTGAACCACATGACACAGATCTGGCAGGACCGGAGACAACTGGGAATTGACACAGTGGTTTGGGATGTGGCCATGGTTCTCTCCACACATCTGGAGATGGGAGCTGTGGAGCTTTTGGGCTGCCCTGCAGTGAAACTGGGTGCTGGCATAGGGCTGATGGGCATAGTGGCTGCCCTGCTGGGTGCTCATGTGACTATCACAGATCGAAAAGTAGCATTAGAGTTTTGTAAATCAAGTGTTCAAGGCAATTTACCTCCTTGTATCCAACCCAGAGCTTTTGTTAAGGAGCTGACTTGGGGAAAGAATTTGGGGAGTTTTTCTCCTAGAGATTTTGACCTGATACTTGGAGCCGATATCATATATTTAGAAGAAACATTCACGGATCTTCTTCAAACACTGGACCATCTCTGTAGCAATCACTCCATGATTCTTTTACCTTGCTGAATTCACTATGAACGGAATAACTTTTGAGCAATGCTGGAGAGGCAGTTTACTATAAGGTTCACTATGATACTGAGAAAGATGTGCATACTTATACAGAAGAGAAGCCACAGCAAGGACCTACAGTTGGCTATCATTTATAAGAATGCTGTCATTGAGGGTGTTGATTAAGGTCTTG
>XM_030802423.1
GGCCCGCAGTGTCGCTCACTTCCAGGGTCGGGGAGACGGAACTGCGGCGACCGTGTATTTCTGGTTTATCAAACCGCTAACACCCAGTCTAAGGGCAGGTCTGAGCAGAGGGCGGGGTGCAGGCGGGATGGCCCTCGTGCCCTATGAGGAGACAACGGAATTTGGATTGCAGAAATTCCACAAGCCTCTTGCAACTTTTTCCTTTGCAAACCACACGATCCAGATCCGGCAGAACTGGAGACACCTGGGAGTCGCAGCGGTGGTTTGGGATGCGGCCATCGTTCTTTCCACGTATCTGGAGATGGGAGCTGTGGAGCTCAGGGGCCGCTCTGCCGTGGAGCTGGGTGCTGGCACGGGGCTGGTGGGCATAGTGGCTGCCCTGCTGGGTGCTCATGTGACTATCACGGATCGAAAAGTAGCATTAGAATTTCTTAAATCAAACGTTCAAGCCAACTTACCTCCTCATATCCAACCCAAAACTGTTGTTAAGGAGCTGACTTGGGGACAAAATTTGGGGAGTTTTTCTCCTGGAGAATTTGACCTGATACTTGGAGCTGATATCATATATTTAGAAGAAACATTCACAGATCTTCTTCAAACACTGGAACATCTCTGTAGCAATCACTCTGTGATTCTTTTAGCATGCCGAATTCGCTATGAACGGGATAACAACTTCTTAGCAATGCTGGAGAGGCAATTTACTGTGAGAAAGGTTCACTATGATCCTGAAAAAGATGTACATATTTACGAAGCACAGAAGAGAAACCAGAAGGAGGACTTATAATTGCCTATAATTTATAAGAATGTTGTCATTGAGTGTGTCACTTAAGGTCTTAGACTGCAAATCTAACCATATTTAATGAAATGTCTTACTGTACAAAAAGTCTAAACCAAAGGTTCTCAGGGGAGAAAGCACATGTGCAGTTTTAAAACAAAGCAGTGCTTTGTCCCATTGCTGTGATTTTTAGTCAGACTTCACTCAGGCTGAAATCCAATTAACATTAAAGGATTAAGTGTGAGATTTTGATTTATGCTATTTCTGTATCCCATACTCCTCCCTTTTAATAAACAGTTTCCAGTGATGATA

Publications

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