Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name Cwc15P3
Plot displaying the genomic locations of a retrocopy (in chr7) and its respective parental gene (in chr8). Each line represents a retrocopy.
Species Rattus norvegicus
Coordinates chr7:38478035-38478196  UCSC
Strand +
Parental Sequence NM_001024987.1
Parental seq. overlap 134 bp
Parental seq. overlap (%) 9.9%
Genomic Region Intergenic
Retrocopy Summary Cwc15P3, located on chr7:38478035-38478196, is a retrocopy of the parental gene Cwc15. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Cwc15
Full Name CWC15 spliceosome-associated protein
Also known as RGD1310669
Coordinate chr8:12994131-13004958
Strand +
Gene summary Predicted to enable RNA binding activity. Predicted to be involved in mRNA cis splicing, via spliceosome. Predicted to be located in mitochondrion and nuclear speck. Predicted to be part of U2-type catalytic step 2 spliceosome. Orthologous to human CWC15 (CWC15 spliceosome associated protein homolog). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Mouse Mus musculus Cwc15P2
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>Cwc15P3
TAAGGAAAGAGCTAAAGCACAGGCCAGGAAGGAAAAGGAACAAAAAGCAGAATGGAGAATTCCCAAGGAAAACATTCTGCGTGGAAGCCCTCTCTTTAATCTCACTGACACACCCCAGTCTCAGGGCCACTTTAAGGTTAAAAGAAGTTAGGACGATGATGT
>NM_001024987.1
CAGGTGTAGAGACTGGAAGTTCTGCATTTTGCTTCCGGTTTTGCGCAGAGATTTCTGGGAGTTAAGGGTCGCAATGGTTCGTGAGTGAGCTTCTGAAGGCACTGCGTCGAACCCCCGCCACAAAGATGACAACAGCAGCCAGGCCAACTTTTGAACCTGCAAGAGGTGGGAGAGGAAAAGGAGAAGGTGATTTGAGCCAGCTCTCCAAGCAGTATTCAAGCAGAGACCTTCCCTCTCATACAAAGATAAAGTACAGACAAACCACACAGGATGCCCCTGAAGAGGTTCGCAACCGTGACTTCAGGAGAGAGTTGGAAGAGAGGGAGAGAGCTGCTGCAAGGGAGAAAAATAGGGACCGTCCAACCCGAGAACACACAACTTCCTCTTCGGTGTCCAAGAAGCCCCGCTTAGACCAGATTCCTGCTGCCAACCTTGATGCTGACGATCCTCTCACAGATgaggaagatgaggattttgaagaggaaagcgatgacgatgaCACTGCAGCTCTTCTTGCAGAGCTAGAAAAGATCAAGAAGGAGAGAGCTGAAGAGCAGGCCAGAAAGGAGCAAGAACAAAAAGCAGAGGAAGAGAGAATTCGCATGGAAAACATTCTGAGTGGAAACCCTCTCCTGAATCTCACGGGCCCGTCCCAGCCTCAGGCCAACTTCAAGGTTAAAAGAAGGTGGGACGATGATGTTGTTTTTAAGAACTGTGCAAAGGGTATAGATGATCAAAAGAAAGACAAAAGATTTGTAAACGATACGCTGCGATCTGAATTTCACAAAAAGTTCATGGAGAAATATATCAAGTAGTACAGTTTTATGTGCTTAATTAAAGACTAAAGTGTCCAGGATCCATTTGATGTTTGGTTTTGTTCTTTCCCAGCTCTGACTTTCTCAATCCCTTCCCTAAGTGTCGTACTTTACTGGATAATGGGTTTAGAAATGGGTTGAgggctggagagatggcttagcggttaagagcacccgactgctcttccagaggtcatgagttcaattcccagcaaccacatggtggctcacaaccatctgtaaagagatccgatgccctcttctggtgtatctgaagacagctacagtgtactcatatataataaataataaatctttaaaaaaaaaaAAGAAAGAAATGGGTTGAACCAGGCCTTAGTTTCTTTTTAATATGGGGAAAGGGGAAATCTGCTTGTGATAAATATTTTTAACCTAAATCATTGTCCCCAACTTTTTGCTATAATTTATACAGCTTATAAAAAGTTGCATAACTCTTTTCAAAATGAAAATTATCTTTGTGTGCTGTGTTTTTAATACATTAAGTTTTCTCCTTTA

Publications

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