Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name Hspd1P21
Plot displaying the genomic locations of a retrocopy (in chr14) and its respective parental gene (in chr9). Each line represents a retrocopy.
Species Rattus norvegicus
Coordinates chr14:61955684-61957904  UCSC
Strand +
Parental Sequence NM_022229.2
Parental seq. overlap 2114 bp
Parental seq. overlap (%) 94.5%
Genomic Region Intragenic (Kctd8)
Retrocopy Summary Hspd1P21, located on chr14:61955684-61957904, is a retrocopy of the parental gene Hspd1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Hspd1
Full Name heat shock protein family D (Hsp60) member 1
Also known as Hsp60|Hspd1-30p
Coordinate chr9:61680529-61691202
Strand -
Gene summary Enables modification-dependent protein binding activity. Involved in several processes, including negative regulation of apoptotic process; positive regulation of cytokine production; and response to ischemia. Located in several cellular components, including mitochondrial crista; peroxisomal matrix; and zymogen granule. Used to study Alzheimer's disease and low tension glaucoma. Biomarker of several diseases, including artery disease (multiple); hydrocephalus; hyperglycemia; pulmonary fibrosis; and varicocele. Human ortholog(s) of this gene implicated in artery disease (multiple); autistic disorder; glucose intolerance; hereditary spastic paraplegia (multiple); and hypomyelinating leukodystrophy 4. Orthologous to human HSPD1 (heat shock protein family D (Hsp60) member 1). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>Hspd1P21
CCTCACTCGCCACAAACTGCCTGCCTTGCCTCGTGTTCTCTCGCTGACCGGCAGAAATGCTTTGATTACCCACAGTCCTTTGCCAGATCAGACCAGTGTCTCAGGCACTGGCTCCTCATCTCACTCAGGCCTATGCCAAAGATGTAAAATTTGGTGCGGATCTCAAGCCTTAATGCTTCAAGGTGTAGACCTTTTAGCTGATGCTGTAGCTGTTCCAATGGGGCCAAAAGGAAGAACAGTGATTATTGAACAGAGTTGGGGAAGTCCCAAAGTGACAAAAGATGGGGTCACTGTTGCAAAGTCAATCGATTTAAAGGATAAATACAAAAATATTGGAACTGAACTTGTTCAGGATGTTGCCGATAACACAAACAAAGAGGCTGGGGATGGCACCACCACTGCCACTGTTTTGGCACGGTCTATTGCCAAGGAGGGCTTGGAGAAGATCAGCCAAGGGGCTAATCCAGTGGAAATCCAGAGACCTGTGATGTTGGCTGTTGATGCTGTAATTGCTGAACTTAAGAAACAATCTAAACCTGTGACAACCCCTGAAGAGACTGCTCAGGTTGCTACAACTTCTGCAAACGGAGACAAAGACACTGGGAACATCATTTCTGATGCAGTGAAGAAGGTTGGAAGAAAGGGCGTCATCACAGTGAATGATGGAAAACCCTGAATGATGAGCTAGAAATTATTGAAGGCATGAAGTTCGATAGAGGATATATTTCCCCATATTTTATTAACACATCAAAAGGTCAAAAATGTGACTTCCAAGATGCCTATGTTTCATTGAGTGAAAAGAAAATTTCTAGTGTTCAGTCCATTGTACCTGCTCTTGAAATTGCCAATGCTCATCGGAAGCCCTTGGTCACAATTGCTGAAGATGTTGATGGAGAAGCTCTTAGCACACCGGTTTTGAACAGGCTAAAAGTTGGTCTTCAGGTTGTAGCAGACAAAGCTCCAGGGTTTGGGGACAACAGGAAGAACCAGCTTAAAGATATGACTATCGCTACTGGTAGTGCAGTGTTTGGAGAAGAGGAGTTGAATCTAAATCTTGAAGATGTTCAAGCTCATGATTTAGGAAAAGTTGGACAGGTCATTGTCACCAAAGATGATGCCATGCTTTTGAAAGGAAAAGGTGACAAAGCTCACATTGAAAAAATGTATTCAAGAAATCACTGAGCAGCTAGACGTCACAACTAGTGAATATGAAAAGGAAAAGCTGAACGAGCGACTTGCTAAACTTCCAGATGGAGTAGCTGTGTTGAAGGTTGGAGGGACAAGTGATGTTGAAGTGAATGAGAAGAAAGACAGAGTTACAGATGCTCTCAATGCCACAAGAGCAGCTGTTGAAGAAGCCATTGTTCTGGAGGGGACTGTGCTCTGCTTTGGTGCATCCCAGCCTTGGATTCATTAAACCTGCTAATGAAGATCAGAAGATAGGTATAGAAATTGTCAAAAGAGCACTTAAAATTCCTGCAATGACGATTGCTAAGAATGCAGGTGTTGAAGGATCTTTGATAGTTGAGAAAATTCTGCAGAGTTCCTCAGAGTTGGTTATGACGCCATGCTTGGAGATTTTGTGAACATGGTGAAAAGGTTGATCCAACAAAGGTTGTAAGAACTGCTTTACTGGATGCTGCTGGGGTGGTCTCCTTGCTAACTACAGCCGAAGCTGTAGTGACAGAAATTCCTAAAGAAGAGAAGGACCCTGGAATGGGTTCAATGAGTGGAATGCGAGGGGCTGTGGGAGGTGGCCTGTTCTAACTCTTAGAATAGTGCTTTGCCCTTATCAATGAACTGTGACAGGAAGCTCCAGGCAGGTTCCTCACCAATAACTTCAGAGAAGTCACCTGAAGAAAATGACTGAAGAGAAGGCTGGCTGATCACTGTAACCGTCACTTATTGGTTTCCTTTGACAATACATAATGGTTTACTGTTGTCATTGTCCACGCCTACAGATAATTTATTCTGTATTTTTGAATAAAGACATTAGTACATTCCTGATGCTGGGTGCAAGAGTCATATACCAGTGTCCTGCTTTCACGTTAAATCATTGAAGCATCTCTACTGTTCTGTCAGCATCAGGACTGTAGCGCTGTGTCACCACATGAGAAGTTCAGAAGCAGCCTTTCTGTGGAGGGTGAGAATGATTGTGTACCGAGTAGAGAAGTATCCAATTATATGACAACCTTTGTGTAATAAAATTTTGTTTAAAGTT
>NM_022229.2
CTCACTCGCCGCAGACGGCCTGCCTCGCCTCGTGCTCTTCCGCCGCCGCCCCGCAGAAATGCTTCGACTACCCACAGTCCTTCGCCAGATGAGACCAGTGTCTCGGGCACTGGCTCCTCATCTCACTCGGGCCTATGCCAAAGATGTAAAATTTGGTGCGGATGCTCGAGCCTTAATGCTTCAAGGTGTAGACCTTTTAGCCGATGCTGTAGCTGTTACAATGGGGCCAAAGGGAAGAACAGTGATTATTGAACAGAGTTGGGGAAGTCCCAAAGTAACAAAAGATGGGGTCACTGTTGCAAAGTCAATTGATTTAAAGGATAAATACAAAAATATCGGAGCTAAGCTTGTTCAGGATGTTGCCAATAACACAAATGAAGAGGCTGGGGATGGCACCACCACTGCCACTGTTCTGGCACGGTCTATTGCCAAGGAGGGCTTTGAGAAGATCAGCAAAGGGGCTAATCCAGTGGAAATCCGGAGAGGTGTGATGTTGGCTGTTGATGCTGTAATTGCTGAACTTAAGAAACAATCTAAACCTGTGACAACCCCTGAAGAAATTGCTCAGGTTGCTACAATTTCTGCAAACGGAGACAAAGACATTGGGAACATCATTTCTGATGCAATGAAGAAGGTTGGAAGAAAGGGTGTCATCACAGTGAAGGATGGAAAAACCCTGAATGATGAGCTAGAAATTATTGAAGGCATGAAGTTTGATAGAGGATATATTTCCCCATATTTTATTAACACATCAAAAGGTCAAAAATGTGAATTCCAAGATGCCTATGTTTTGTTGAGTGAAAAGAAAATTTCTAGTGTTCAGTCCATTGTACCTGCTCTTGAAATTGCCAATGCTCACCGGAAGCCCTTGGTCATAATTGCTGAAGATGTTGATGGAGAAGCTCTTAGCACACTGGTTTTGAACAGGCTAAAAGTTGGTCTTCAGGTTGTAGCAGTCAAAGCTCCAGGGTTTGGGGACAACAGGAAGAACCAGCTTAAAGATATGGCTATCGCTACTGGTGGTGCGGTGTTTGGAGAAGAGGGTTTGAATCTAAATCTTGAAGATGTTCAAGCTCATGATTTAGGGAAAGTTGGAGAGGTCATCGTCACCAAAGATGATGCCATGCTTTTGAAAGGAAAAGGTGACAAAGCTCACATTGAAAAACGTATTCAAGAAATCACTGAGCAGCTAGACATCACAACTAGTGAATATGAGAAGGAAAAGCTGAACGAGCGACTTGCTAAACTCTCAGATGGAGTAGCTGTGTTGAAGGTTGGAGGGACAAGTGATGTTGAAGTGAATGAGAAGAAAGACAGAGTTACAGATGCTCTCAATGCTACAAGAGCAGCTGTTGAAGAAGGCATTGTTCTAGGAGGGGGCTGTGCTCTACTTCGGTGCATCCCAGCCTTGGATTCATTAAAGCCTGCTAATGAAGATCAGAAGATAGGTATAGAAATTATTAAAAGAGCACTTAAAATTCCTGCAATGACAATTGCTAAGAATGCAGGTGTTGAAGGATCTTTGATAGTTGAAAAAATTCTGCAGAGTTCCTCAGAGGTTGGCTATGATGCCATGCTTGGAGATTTTGTGAACATGGTGGAAAAGGGAATCATTGATCCAACAAAGGTTGTAAGAACTGCTTTACTGGATGCTGCTGGGGTGGCCTCCCTGCTAACTACAGCCGAAGCTGTAGTGACAGAAATTCCTAAAGAAGAGAAGGACCCTGGAATGGGTGCAATGGGTGGAATGGGAGGGGGTATGGGAGGTGGCATGTTCTAACTCCTAGAATAGTGCTTTGCCCTTATCAATGAACTGTGGCAGGAAGCTCAAGGCAGGTTCCTCACCAATAACTTCAGAGAAGTCACCTGAAGAAAATGACTGAAGAGAAGGCTGGCTGATCACTGTAACCATCAGTTACTGGTTTCCTTTGACAATACATAATGGTTTACTGCTGTCATTGTCCATGCCTACAGATAATTTATTTTGTATTTTTGAATAAAGACATTTGTACATTCCTGATGCTGGGTGCAAGAGCCAGTGTCCTGCTTTCAACTTAAATCACTGAGGCATCTCTACTGTTCTGTTAGCATCAGGACTGTAGCGCTGTGTCACCACATGAGAAGTTCAGAAGCAGCCTTTCTGTGGAGGGTGAGAATGATTGTGTACAGAGTAGAGAAGTATCCAATTATGTGACAACCTTTGTGTAATAAAATTTTGTTTAAAGTT

Publications

PMID - Link Title