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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RGD1566265P2
Plot displaying the genomic locations of a retrocopy (in chr18) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Rattus norvegicus
Coordinates chr18:62923752-62924269  UCSC
Strand +
Parental Sequence NM_001134589.1
Parental seq. overlap 425 bp
Parental seq. overlap (%) 34.6%
Genomic Region Intergenic
Retrocopy Summary RGD1566265P2, located on chr18:62923752-62924269, is a retrocopy of the parental gene Chmp1b2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Chmp1b2
Full Name charged multivesicular body protein 1B2
Also known as RGD1566265
Coordinate chrX:78870964-78911601
Strand -
Gene summary Predicted to be involved in endosome transport via multivesicular body sorting pathway; late endosome to vacuole transport; and protein transport. Predicted to be located in late endosome membrane. Predicted to be part of ESCRT III complex. Predicted to be active in multivesicular body. Orthologous to human CHMP1B (charged multivesicular body protein 1B). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Mouse Mus musculus 2610002M06RikP2
Chinese hamster Cricetulus griseus LOC100755586_1P1
Horse Equus caballus LOC100071734P2
Pale spear-nosed bat Phyllostomus discolor CHMP1B2P3
Velvety free-tailed bat Molossus molossus CHMP1B2P2
Greater mouse-eared bat Myotis myotis CHMP1B2P3
Kuhl's pipistrelle Pipistrellus kuhlii CHMP1B2P1
Greater horseshoe bat Rhinolophus ferrumequinum CHMP1B2P3
Egyptian rousette Rousettus aegyptiacus CHMP1B2P1
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RGD1566265P2
TTGTCCAACATGGAGAAACATCTGTTCAACCTGAAATTCGCGGCCAAAGAACTGAACAGGAGTGCCAAAAAATGCGACAAGGAAGAAAAGGCCGAAAAGGCCAAAATTAAAAAGGCCATTCAGAAGGGCAACATGGAAGTTGCGAGGATACACGCCGAAAATGCCATCCGCCAGAAGAATCAAGCGGTAAACTTCTTGAGAATGAGTGCACGAGTGGATGCGGTCGCTGCCAGAGTCCAGACTGCAGTGACGATGGGCAAAGTGACCAAGTCCATGGCGGGTGTGGTTAAGTCGATGGACGCGACGTTGAAAACTATGAATCTGGAAAAGATCTCAGCTTTGATGGACAAATTCGAACACCAGTTTGAGACCCTGGACGTCCAGACTCAGCAAATGGAAGACACGATGAGCAGCACGACGACGTTGACCACTCCCCAGAACCAAGTGGATATGCTGCTCCAGGAAATGGCAGATGAGGCGGGCCTCGATCTCAACATGGAGCTGCCTCAGGGCCAGAC
>NM_001134589.1
AACCGAAACAGGAAGTGGGCTAGGATCCCTCGAAACCAGCATCAACTGCTATCTTCTGCGCGTCCGAGCGACCCACGACCCGCGACTCGCGGGTGCCCGACCCCTGTCCTGAGTGTTACCGGCCCCTCCCCTTCCTCCCACCCGGTGAACTGGAGAGATCATGTCGAACATGGAGAAACACTTATTTAACTTGAAGTTTGCTGCAAAAGAACTGAATAGGAATGCCAAGAAGTGTGATAAAGAAGAAAAAGCTGAAAAGGCCAAGATAAAAAAGGCCATTCAGAAGGGCAATACAGAAGTTGCCAGAATACATGCTGAAAATGCAATCCGTCAGAAAAACCAAGCAATCAATTTCTTGAGAATGAGTGCTAGAGTTGATGCTGTGGCAGCCAGAGTTCAAACTGCAGTAACAATGGGCAAGGTGACAAAATCCATGGCAGGTGTAGTTAAATCTATGGATGCTACACTGAGGAGTATGAACCTGGAGAAGATTTCTGCCTTGATGGACAAATTCGAACATCAGTTTGAAACATTGGATGTTCAGACCCAGCAAATGGAAGATACAATGAGTAGCACTACTACCCTCACAACGCCACAGAACCAAGTGGATATGCTGCTTCAGGAAATGGCAGATGAAGCTGGCCTTGATCTCAATATGGAACTACCACAGGGTCAGACAGGGTCTGTTGGTGCAAGTGTTGCTTCTACAGAACAGGATGAACTGTCACAGAGACTTGCTCGTCTTCGTGATCAAGTGTAACTCAAATAACTGGTGCTTCTGTTTCCTCCACATATTTCAGAAACATCATTTATGTGTGTATAGATAGATAGGTTGTATTCTAGTTATAAAAACATCATCCATGACAGGATGTTTGAACATCATTTACATATGATGCTTTCTTTTGCCTTGTGGATTTCACAGTGCATTGAGAAATTCTAGGGAATTTCCATATTGGCAGATTTTATAGTTCTATATATTATGTGTAAAAGTGTGAGGGACATATTTTTGTAGATGTCTTTGGCAAAGCTAGCATTAGTTTTCTGTATATTATACATCTTCCTCAAATATTAGAGCAAACATCTAGCACCAAAGTACTTCTAAGTAATTTTGTCCAAATAACATATAGAATAAAAGCCTTGTTTTTACTTATTGAAAGTAACTTTCAGTTATTGTCTGTGATGAAATATGATTTTGTAAAAATAAAAACAGGGAAAGCATGTTCATTT

Publications

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