RCPedia: Rtcs

Summary

Retrocopy Name	2610002M06RikP2	Plot displaying the genomic locations of a retrocopy (in chr18) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species	Mus musculus
Coordinates	chr18:67338652-67339167 UCSC
Strand	+
Parental Sequence	NM_025921.3
Parental seq. overlap	419 bp
Parental seq. overlap (%)	7.2%
Genomic Region	Intergenic
Retrocopy Summary	2610002M06RikP2, located on chr18:67338652-67339167, is a retrocopy of the parental gene Chmp1b2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name	Chmp1b2
Full Name	charged multivesicular body protein 1B2
Also known as	2610002M06Rik\|8430408J07Rik
Coordinate	chrX:106826357-106859940
Strand	-
Gene summary	Predicted to enable MIT domain binding activity and identical protein binding activity. Predicted to be involved in several processes, including midbody abscission; regulation of cell cycle process; and viral budding via host ESCRT complex. Predicted to be located in endosome membrane; midbody; and nucleoplasm. Predicted to be part of ESCRT III complex and membrane coat. Predicted to be active in multivesicular body. Orthologous to several human genes including CHMP1B (charged multivesicular body protein 1B). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species	Scientific Name	Retrocopy
Rat	Rattus norvegicus	RGD1566265P2
Chinese hamster	Cricetulus griseus	LOC100755586_1P1
Dolphin	Tursiops truncatus	LOC101320609P1
Horse	Equus caballus	LOC100071734P2
Pale spear-nosed bat	Phyllostomus discolor	CHMP1B2P3
Velvety free-tailed bat	Molossus molossus	CHMP1B2P2
Greater mouse-eared bat	Myotis myotis	CHMP1B2P3
Greater horseshoe bat	Rhinolophus ferrumequinum	CHMP1B2P3
Egyptian rousette	Rousettus aegyptiacus	CHMP1B2P1
Human	Homo sapiens	Without Homology
Chimpanzee	Pan troglodytes	Without Homology
Bonobo	Pan paniscus	Without Homology
Gorilla	Gorilla gorilla	Without Homology
Orangutan	Pongo abelii	Without Homology
Gibbon	Nomascus leucogenys	Without Homology
Green monkey	Chlorocebus sabaeus	Without Homology
Crab-eating macaque	Macaca fascicularis	Without Homology
Rhesus	Macaca mulatta	Without Homology
Baboon	Papio anubis	Without Homology
Golden snub-nosed monkey	Rhinopithecus roxellana	Without Homology
Marmoset	Callithrix jacchus	Without Homology
Mouse lemur	Microcebus murinus	Without Homology
Rabbit	Oryctolagus cuniculus	Without Homology
Pig	Sus scrofa	Without Homology
Cow	Bos taurus	Without Homology
Sheep	Ovis aries	Without Homology
Dog	Canis familiaris	Without Homology
Panda	Ailuropoda melanoleuca	Without Homology
Cat	Felis catus	Without Homology
Kuhl's pipistrelle	Pipistrellus kuhlii	Without Homology
Sloth	Choloepus didactylus	Without Homology
Tasmanian Devil	Sarcophilus harrisii	Without Homology
Opossum	Monodelphis domestica	Without Homology
Platypus	Ornithorhynchus anatinus	Without Homology
Chicken	Gallus gallus	Without Homology
Turkey	Meleagris gallopavo	Without Homology
Zebra Finch	Taeniopygia guttata	Without Homology
Budgerigar	Melopsittacus undulatus	Without Homology
Painted Turtle	Chrysemys picta	Without Homology
Lizard	Anolis Carolinensis	Without Homology
Frog	Xenopus tropicalis	Without Homology
Zebrafish	Danio rerio	Without Homology
Drosophila	Drosophila melanogaster	Without Homology

Expression

Related Sequence

>2610002M06RikP2
GGAAGAAAAGGCCGAAAAGGCCAAAATTAAAAAGGCCATTCAGAAGGGCAACATGGAAGTTGCGAGGATTCACGCCGAAAATGCCATCCGCCAGAAGAATCAAGGGGTGAACTTCTTGAGAATGAGTGCACGAGTGGATGCGGTGGCGGCCCGTGTCCAGACTGCAGTGACGATGGGCAAAGTGACCAAGTCCATGGCGGGTGTGGTTAAGTCGATGGACGCGACGTTGAAAAGTATGAATCTGGAGAAGATCTCCGCTTTGATGGACAAATTCGAACACCAGTTCGAGACTCTGGACGTCCAGACGCAGCAAATGGAAGACACAATGAGCAGCACGACGACGCTGACCACTCCCCAGAACCAGGTGGATATGCTGCTCCAGGAAATGGCAGATGAGGCGGGCCTCGATCTCAACATGGAGCTGCCTCAGGGCCAGACCGGTTCCGTGGGAACGAGCGTGGCTTCGGCTGAGCAAGATGAACTGTCCCAGAGACTGGCCCGCCTTCGGGATCAAGT

>NM_025921.3
TAGCTCGTGGGACTCCACCCACCACGGGTTCTAAACCGAAACAGGAAGTGGGCTAGGATCCCTCGAAACCCGCTACAACCGCCACCCTCCGCGCGCCCAAGCGACCCACAACTCGCGGGTCCAGCCCCTGTCCCGCGTGttacctgcccctccccctcctcccgccCGGTGAACTCGAGAGATCATGTCGAACATGGAGAAACACTTATTTAACTTGAAGTTTGCTGCAAAAGAACTTAATAGGAATGCCAAGAAGtgtgataaagaagaaaaagctgAAAAGGCCAAGATAAAAAAGGCCATTCAGAAGGGCAATACAGAAGTTGCAAGAATACATGCTGAAAATGCAATCCGTCAGAAAAACCAAGCAATCAATTTCTTGAGAATGAGTGCTAGGGTTGATGCTGTGGCAGCCAGAGTTCAAACTGCAGTAACAATGGGCAAGGTGACAAAATCCATGGCAGGTGTAGTTAAATCTATGGATGCTACATTGAGGAGTATGAACCTTGAGAAGATTTCTGCCTTAATGGACAAATTTGAACATCAGTTTGAAACATTGGATGTTCAGACACAGCAAATGGAAGATACAATGAGTAGCACTACTACCCTTACGACACCACAGaaCCAAGTGGATATGCTGCTCCAGGAAATGGCAGATGAAGCTGGCCTCGATCTCAATATGGAACTACCACAGGGTCAGACAGGGTCTGTTGGTGCAAGTGTTGCTTCTACAGAGCAGGATGAACTGTCACAGAGGCTTGCTCGTCTTCGTGATCAAGTGTAACTTAAATAACTGGTGCTTCTGTTCCTCCACATATTTCTGAgccatcatttgtgtgtgtgtctatagatAAGGTGTATTCCAGTTACAAAAACATCATACATGACAGGATGTTTGGACATCATTTCtataagatgctttcttttgccttgtGTATTTCACAGTGCATTGCGAAATTCCAAGGAATTTCCACATTGGCAGATTTTATAGTTCTATATATTGTGTGTAAAAGTGTGAGGGACATATTTTTCTAGATGTCTTTGGCAAAGCTAGCATTAGTTTTCTGTATATTATACATCTTCCGCAAATATTAGAGCAAACATCTAGCACCAAAGTAATGCTAAGTAAAGTAATTTTGTCAGAATAATGTATAAAGGCTTTGTTTTTACTTATTGAAAGTAACTTTCAATTATTGTCTGTGATGAATTTtgattttgtaaaaataaaaacaggaaagcatGTTCATTTAATATGTTCGCATAACCCAGACCATCTTATTTTAAGTATCACAAGATAGACTATACAATTTCCATGggatttttgaaaattatttctattttgtatgtatggttgttttgcctgcatgttaaATTGTGTACTCacttgtgtgtctggtgcctacagaggccagaagaggacattggattcccCAGGAACTAGAGCTATAGACAATTGGGAGCCAACATGTGGATACTAGAATTCAAACCCATTTCTTCtagaagaccagccagtgctcttaactcctgagccatgtGTCTAGCCTCTGTTTTGTttcgttgctgttgttgttttgcttgtttattttagagacagggcAGAAATATATAGCCCAGAGTTCCCTGAAACTCAGTGAGCCTCCAGCATTGGTCTCTAAGTatataccaccatacccagctcattTTCtatgatttgggggtgggggttgttatGCACATTagttattttttctgtttctatgataaaTAACCGTGCTCAAAAGTGacttatggaagaaagaaagtattTTGGTTTATGGTTCCAGGGAAATGAGGgctccatcatggtggggaggtgTGGCAGCAAGAGCAGGTAGCTGGTACATGTTTAAtgacacacacaaagcagaaagaACAGGCTGCCAGTGTAACAGACCTAGAAGCTCTCAAAGCCAGTGACATACTTCATTTAGTAAGGTTGCATATCTCCATACCTTCTCCATAAGGCACCACCAACTGGGAAACAATTATTCAAGTACATGAGTCTATGGAAAAATGTCTCGTTCAGACCACTGCATTCCTCTCCCTGGCTTCCATAGACTTatggccatatcataatgcaaaatgtatttacTCTGATGCTTAAAGTGCCCATGGTCTTTCTCAATCTCAATACTATTTGAAATTTCAAAGTCCAGCATATCTTGTGAGACTCGAGACAATCTCTAGCCACTGATAAGATCTAAAAGCAAATAATATACTTCCAACATACGATGGCACAGGTTACACATTATCATtttagaagggaggaagggggacatgatgaggaaatactggactaCAGAGAGACTGAAAGCTCACAAGGCATACATATAAGCAAATCCTGTAGCTCTATGTGGGATGTCTGGGACTACTTTCCGAGGGTTTGGATGGCTTAACTCCTCCAGCTTTGCTGCCTGATTTAATAGCTCACTCTCTAGTAACATCTTCTACGttagttacttctctgttgctgcgATTAagcaccatgaccagaagcaatttataaatagaagagtttattttggcttacagttccagagggataagaaaGTGTGCACCATGGCAGGGATGCATGGTAGCAGGATCAGGAAGCCAAGAAATCATGCTTTCTATTATGCTGTACACATGACGCAGAAAGAGCCAGCTGGAAGTGTGGCAAGACACTCCCAATGCCTGTTGCTGGTGGAATAATTCCTCCAACAGAGTTTGTACAATGACCTGTACCATAACCTTCCCAACTGGTGAACAAagtttcaaatatgtgagcctatagGAGACTCATTCAATTCAGAACATTATGTAAAGAGAAACAGAGTAAATATTTACTTGGTTTTAATCCACTGTAAAGTTTAAATCATTATAGTTTTTAGCCAGTAATTTAATGATGACTGTTCATTAATTTTTAAGACCTTTTAATGGACAATTTATTATATAACTAGGAAAATTCTGCAACATTAATCCAAAGTTTGTATTGGGATACCCTAGATATCCATAGAAGAGATTTGATGGACAAAAGTATTTATGACATAAAGAATGTGTTCTCTGTTGGTATGAATTAAATAGTTTCTGTTCTTTTAACTTGAATAAAAAATTGTTAGATTTATTACTACCACTTAGCTCCACAACTAGCTGTTCATTCTTTTATGTTGCAACCATGTCAGActtaccttttaaaatattactatcAGGGCTGTAAAGTTAATACTACCATTTCAAGAGGATCTGCCTTTGTGTCTCAGCAGCACATCAGTTACCTCACAACATCCTGTAAATCTGCCTCCTGGGGATTCAGTGACCTTTCCTGGTTCCCACAGGGTACCTGAACTCATGTGTatagatgcacacagacacacacataatttttaaaataaagatatacTGGACATGGtcacacatacctttaatctcagcactcaggagactgaggctgtgagttccaggccagccgaaGATACATTATGAGACCAcatctcaaaaaatatttgtaaaacattGATGAGGCAGGTAAGATAGTTGAGTAGATataagcacttgccaccaagcctggcaacctgagttcagttcctgtgACCCACATGGTAGATGTAAAGATTTGCtcctgcaaactgtcctctgacctccacacacattccATTGCATGCACacaagttttaaaattagaaactaCATTAATGGACactaagttttatttttcccttcatTTGTTCACTCTTTTATCAATGTAATGAAAATGTACCTCTTAGACTTTATTCCTAAACCAATAACCTAAGCATGTGATGGTATCATTTGGTTGAACATATATACTCAGATACTTAAAACATCTTGTTGCACTTTCCCCTGTTGGATAAAAAGGCTGATGATAATTCTCCATTTCTTTATGTGTCTTAATGCTTAAAGCCATCTGGTTGCCTGTGAACCATTTTAGGTACCATTATGGACTAGGCTATTTTACCTGGTTAATTGATTGCTTACAAATACCACTTGGAGAAGAAGGAATGAGTAACTCTGAGAAGAGATGTGGACTTTAGAAAATTCTCAGGAAGGAGCATCTGTAGTATTGGgagaaagcaaaatgaaatgaTAGACTGGCAGAAGTAAGCTTGCCAGCTTCCTATGGATTAATAATGTTTGTTGCTAATGATGTTGAGATAAACTGAGAAAGCGTGCCATTTAAAAATTCTAATAGgaaatagagagatggctcagagttaagaGTACTGTACGCTCTTGCAgcggacctgggttcagttcccaacacccacatggtggctcacaactgtccaacCCCCCTTTTTAATGTTTATGGGTTTTTGTGCACATATGGTGCATGATATGTGCACTCAGATAtgcatgaataaatattttttgaagttATATTAACTCCTACTATTTTTTCATGGGATGATTTCATAGTGTATTTTTTCACAATCATAATCATTATTTGCCTATTCATTTCTCTAATACTTATTGAGAGTGTACTTGCTATGTGCTATGGCGATTTGGTTTTGAAGATTGAAGGGAGGCAGGGCAAGAAATTCTCAATTAACTACAATTGAAGATACTAAGTGATCTCTACAAGATCAGGCCTAACTCACCTGTGGAGCTGAACTCTAGGATTTTGACTACTTTCTCTGTTGCATAGAATAATGGCATTCATTGTTCACATTGCCACCTACAAACTAAATTATCTTACCTACTTCCAAAAATGGAGAGCATATGAGGAATGGTCAACTCCCTGCATTGTCATGTGTATTCAAAACAAAGTTATTTATCATCTACTGTTGTGGAAAATGTTATTTGggagtttctaccccaccttagatcatttagttcccaaataaaagattCCAAATCTCTATATTTGTAATAAGCTTTGTagtactagagctgggcagatatcaaccctctgtgCTATTTGTTCTACTTCACCATCAGTAATACTGAGACATCACTTGCTCTGTTCTGCCTGgtccactcctactccaacagacTGGCCCTCAGGGCTATGCATCCTTGATTTACCCCCTTGgtgccttcttcctcctctctacaGAAGCCCTGCCTACCATTCTTTTGCCCTGCTACAGGCAATTTTAAATTAAAGTAGCAgggtttgcacaacaaaaactGGTATTTGTGAAAATTCACTTGAGGCAAATAGAccttggggtacagaatttagcattacaatacatagcagcaGACCAATCCTCAACAATTTACTGTATTTCTGATTTTCCACTATTTGGTATTCCTTAGAGATACCTTTCATGAAAATTTCTTTGAAATACACACACTGTATCACCAAATCCTTCAGTATGACCTTATCTAAATTCAGTAACTCAAATGCCTCATTCTaccaaaatatttgaaatataacaaGCCCAAGTAACTTTTGAATGGAGAAGAGATTAACATGGATAAAGTTGGAATGGAATTGGGAGTCTAAGGCTGAGTATTGTGAAAGGAGTGCTTGACATGGCCTTTGGAAAGACGTGGGAGGAATCTGCTGTAGAAAAGTTTTGTCAGTCTCTATGGTACATAGGCTCGGCTTTAGCCCTCATACATGTGATTACTTCAACCTTTGTCAGGGGTCAGCACAATCTGCCTGTTTCATCTTCATCGCCCACACTTGAAAACATcttaatgtctttgtttttcttgtgaGAGAATTAGATCTCAACTATCTCAATATGTTTGACAAGCCTTAGTGTACATTTACACCTGAATTTGACATGTAAATAGCATCTTTGTCAAACTGGAGGGAATGTAAATGATGGATATGTCAGTGCTCAATAAACAGTTCTAGAATGATTATTTGAAA

>NM_025921.3 

TAGCTCGTGGGACTCCACCCACCACGGGTTCTAAACCGAAACAGGAAGTGGGCTAGGATCCCTCGAAACCCGCTACAACCGCCACCCTCCGCGCGCCCAAGCGACCCACAACTCGCGGGTCCAGCCCCTGTCCCGCGTGttacctgcccctccccctcctcccgccCGGTGAACTCGAGAGATCATGTCGAACATGGAGAAACACTTATTTAACTTGAAGTTTGCTGCAAAAGAACTTAATAGGAATGCCAAGAAGtgtgataaagaagaaaaagctgAAAAGGCCAAGATAAAAAAGGCCATTCAGAAGGGCAATACAGAAGTTGCAAGAATACATGCTGAAAATGCAATCCGTCAGAAAAACCAAGCAATCAATTTCTTGAGAATGAGTGCTAGGGTTGATGCTGTGGCAGCCAGAGTTCAAACTGCAGTAACAATGGGCAAGGTGACAAAATCCATGGCAGGTGTAGTTAAATCTATGGATGCTACATTGAGGAGTATGAACCTTGAGAAGATTTCTGCCTTAATGGACAAATTTGAACATCAGTTTGAAACATTGGATGTTCAGACACAGCAAATGGAAGATACAATGAGTAGCACTACTACCCTTACGACACCACAGaaCCAAGTGGATATGCTGCTCCAGGAAATGGCAGATGAAGCTGGCCTCGATCTCAATATGGAACTACCACAGGGTCAGACAGGGTCTGTTGGTGCAAGTGTTGCTTCTACAGAGCAGGATGAACTGTCACAGAGGCTTGCTCGTCTTCGTGATCAAGTGTAACTTAAATAACTGGTGCTTCTGTTCCTCCACATATTTCTGAgccatcatttgtgtgtgtgtctatagatAAGGTGTATTCCAGTTACAAAAACATCATACATGACAGGATGTTTGGACATCATTTCtataagatgctttcttttgccttgtGTATTTCACAGTGCATTGCGAAATTCCAAGGAATTTCCACATTGGCAGATTTTATAGTTCTATATATTGTGTGTAAAAGTGTGAGGGACATATTTTTCTAGATGTCTTTGGCAAAGCTAGCATTAGTTTTCTGTATATTATACATCTTCCGCAAATATTAGAGCAAACATCTAGCACCAAAGTAATGCTAAGTAAAGTAATTTTGTCAGAATAATGTATAAAGGCTTTGTTTTTACTTATTGAAAGTAACTTTCAATTATTGTCTGTGATGAATTTtgattttgtaaaaataaaaacaggaaagcatGTTCATTTAATATGTTCGCATAACCCAGACCATCTTATTTTAAGTATCACAAGATAGACTATACAATTTCCATGggatttttgaaaattatttctattttgtatgtatggttgttttgcctgcatgttaaATTGTGTACTCacttgtgtgtctggtgcctacagaggccagaagaggacattggattcccCAGGAACTAGAGCTATAGACAATTGGGAGCCAACATGTGGATACTAGAATTCAAACCCATTTCTTCtagaagaccagccagtgctcttaactcctgagccatgtGTCTAGCCTCTGTTTTGTttcgttgctgttgttgttttgcttgtttattttagagacagggcAGAAATATATAGCCCAGAGTTCCCTGAAACTCAGTGAGCCTCCAGCATTGGTCTCTAAGTatataccaccatacccagctcattTTCtatgatttgggggtgggggttgttatGCACATTagttattttttctgtttctatgataaaTAACCGTGCTCAAAAGTGacttatggaagaaagaaagtattTTGGTTTATGGTTCCAGGGAAATGAGGgctccatcatggtggggaggtgTGGCAGCAAGAGCAGGTAGCTGGTACATGTTTAAtgacacacacaaagcagaaagaACAGGCTGCCAGTGTAACAGACCTAGAAGCTCTCAAAGCCAGTGACATACTTCATTTAGTAAGGTTGCATATCTCCATACCTTCTCCATAAGGCACCACCAACTGGGAAACAATTATTCAAGTACATGAGTCTATGGAAAAATGTCTCGTTCAGACCACTGCATTCCTCTCCCTGGCTTCCATAGACTTatggccatatcataatgcaaaatgtatttacTCTGATGCTTAAAGTGCCCATGGTCTTTCTCAATCTCAATACTATTTGAAATTTCAAAGTCCAGCATATCTTGTGAGACTCGAGACAATCTCTAGCCACTGATAAGATCTAAAAGCAAATAATATACTTCCAACATACGATGGCACAGGTTACACATTATCATtttagaagggaggaagggggacatgatgaggaaatactggactaCAGAGAGACTGAAAGCTCACAAGGCATACATATAAGCAAATCCTGTAGCTCTATGTGGGATGTCTGGGACTACTTTCCGAGGGTTTGGATGGCTTAACTCCTCCAGCTTTGCTGCCTGATTTAATAGCTCACTCTCTAGTAACATCTTCTACGttagttacttctctgttgctgcgATTAagcaccatgaccagaagcaatttataaatagaagagtttattttggcttacagttccagagggataagaaaGTGTGCACCATGGCAGGGATGCATGGTAGCAGGATCAGGAAGCCAAGAAATCATGCTTTCTATTATGCTGTACACATGACGCAGAAAGAGCCAGCTGGAAGTGTGGCAAGACACTCCCAATGCCTGTTGCTGGTGGAATAATTCCTCCAACAGAGTTTGTACAATGACCTGTACCATAACCTTCCCAACTGGTGAACAAagtttcaaatatgtgagcctatagGAGACTCATTCAATTCAGAACATTATGTAAAGAGAAACAGAGTAAATATTTACTTGGTTTTAATCCACTGTAAAGTTTAAATCATTATAGTTTTTAGCCAGTAATTTAATGATGACTGTTCATTAATTTTTAAGACCTTTTAATGGACAATTTATTATATAACTAGGAAAATTCTGCAACATTAATCCAAAGTTTGTATTGGGATACCCTAGATATCCATAGAAGAGATTTGATGGACAAAAGTATTTATGACATAAAGAATGTGTTCTCTGTTGGTATGAATTAAATAGTTTCTGTTCTTTTAACTTGAATAAAAAATTGTTAGATTTATTACTACCACTTAGCTCCACAACTAGCTGTTCATTCTTTTATGTTGCAACCATGTCAGActtaccttttaaaatattactatcAGGGCTGTAAAGTTAATACTACCATTTCAAGAGGATCTGCCTTTGTGTCTCAGCAGCACATCAGTTACCTCACAACATCCTGTAAATCTGCCTCCTGGGGATTCAGTGACCTTTCCTGGTTCCCACAGGGTACCTGAACTCATGTGTatagatgcacacagacacacacataatttttaaaataaagatatacTGGACATGGtcacacatacctttaatctcagcactcaggagactgaggctgtgagttccaggccagccgaaGATACATTATGAGACCAcatctcaaaaaatatttgtaaaacattGATGAGGCAGGTAAGATAGTTGAGTAGATataagcacttgccaccaagcctggcaacctgagttcagttcctgtgACCCACATGGTAGATGTAAAGATTTGCtcctgcaaactgtcctctgacctccacacacattccATTGCATGCACacaagttttaaaattagaaactaCATTAATGGACactaagttttatttttcccttcatTTGTTCACTCTTTTATCAATGTAATGAAAATGTACCTCTTAGACTTTATTCCTAAACCAATAACCTAAGCATGTGATGGTATCATTTGGTTGAACATATATACTCAGATACTTAAAACATCTTGTTGCACTTTCCCCTGTTGGATAAAAAGGCTGATGATAATTCTCCATTTCTTTATGTGTCTTAATGCTTAAAGCCATCTGGTTGCCTGTGAACCATTTTAGGTACCATTATGGACTAGGCTATTTTACCTGGTTAATTGATTGCTTACAAATACCACTTGGAGAAGAAGGAATGAGTAACTCTGAGAAGAGATGTGGACTTTAGAAAATTCTCAGGAAGGAGCATCTGTAGTATTGGgagaaagcaaaatgaaatgaTAGACTGGCAGAAGTAAGCTTGCCAGCTTCCTATGGATTAATAATGTTTGTTGCTAATGATGTTGAGATAAACTGAGAAAGCGTGCCATTTAAAAATTCTAATAGgaaatagagagatggctcagagttaagaGTACTGTACGCTCTTGCAgcggacctgggttcagttcccaacacccacatggtggctcacaactgtccaacCCCCCTTTTTAATGTTTATGGGTTTTTGTGCACATATGGTGCATGATATGTGCACTCAGATAtgcatgaataaatattttttgaagttATATTAACTCCTACTATTTTTTCATGGGATGATTTCATAGTGTATTTTTTCACAATCATAATCATTATTTGCCTATTCATTTCTCTAATACTTATTGAGAGTGTACTTGCTATGTGCTATGGCGATTTGGTTTTGAAGATTGAAGGGAGGCAGGGCAAGAAATTCTCAATTAACTACAATTGAAGATACTAAGTGATCTCTACAAGATCAGGCCTAACTCACCTGTGGAGCTGAACTCTAGGATTTTGACTACTTTCTCTGTTGCATAGAATAATGGCATTCATTGTTCACATTGCCACCTACAAACTAAATTATCTTACCTACTTCCAAAAATGGAGAGCATATGAGGAATGGTCAACTCCCTGCATTGTCATGTGTATTCAAAACAAAGTTATTTATCATCTACTGTTGTGGAAAATGTTATTTGggagtttctaccccaccttagatcatttagttcccaaataaaagattCCAAATCTCTATATTTGTAATAAGCTTTGTagtactagagctgggcagatatcaaccctctgtgCTATTTGTTCTACTTCACCATCAGTAATACTGAGACATCACTTGCTCTGTTCTGCCTGgtccactcctactccaacagacTGGCCCTCAGGGCTATGCATCCTTGATTTACCCCCTTGgtgccttcttcctcctctctacaGAAGCCCTGCCTACCATTCTTTTGCCCTGCTACAGGCAATTTTAAATTAAAGTAGCAgggtttgcacaacaaaaactGGTATTTGTGAAAATTCACTTGAGGCAAATAGAccttggggtacagaatttagcattacaatacatagcagcaGACCAATCCTCAACAATTTACTGTATTTCTGATTTTCCACTATTTGGTATTCCTTAGAGATACCTTTCATGAAAATTTCTTTGAAATACACACACTGTATCACCAAATCCTTCAGTATGACCTTATCTAAATTCAGTAACTCAAATGCCTCATTCTaccaaaatatttgaaatataacaaGCCCAAGTAACTTTTGAATGGAGAAGAGATTAACATGGATAAAGTTGGAATGGAATTGGGAGTCTAAGGCTGAGTATTGTGAAAGGAGTGCTTGACATGGCCTTTGGAAAGACGTGGGAGGAATCTGCTGTAGAAAAGTTTTGTCAGTCTCTATGGTACATAGGCTCGGCTTTAGCCCTCATACATGTGATTACTTCAACCTTTGTCAGGGGTCAGCACAATCTGCCTGTTTCATCTTCATCGCCCACACTTGAAAACATcttaatgtctttgtttttcttgtgaGAGAATTAGATCTCAACTATCTCAATATGTTTGACAAGCCTTAGTGTACATTTACACCTGAATTTGACATGTAAATAGCATCTTTGTCAAACTGGAGGGAATGTAAATGATGGATATGTCAGTGCTCAATAAACAGTTCTAGAATGATTATTTGAAA

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