Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name MDM2P1
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Macaca mulatta
Coordinates chr13:86795988-86796389  UCSC
Strand -
Parental Sequence NM_001266402.1
Parental seq. overlap 336 bp
Parental seq. overlap (%) 15.8%
Genomic Region Intergenic
Retrocopy Summary MDM2P1, located on chr13:86795988-86796389, is a retrocopy of the parental gene MDM2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name MDM2
Full Name MDM2 proto-oncogene
Also known as -
Coordinate chr11:68342396-68373237
Strand +
Gene summary N/A

Homology

Species Scientific Name Retrocopy
Human Homo sapiens MDM2P1
Chimpanzee Pan troglodytes MDM2P1
Bonobo Pan paniscus MDM2P1
Gorilla Gorilla gorilla MDM2P1
Orangutan Pongo abelii MDM2P1
Gibbon Nomascus leucogenys MDM2P1
Crab-eating macaque Macaca fascicularis MDM2P1
Baboon Papio anubis MDM2P1
Golden snub-nosed monkey Rhinopithecus roxellana MDM2P2
Mouse lemur Microcebus murinus LOC105884627P1
Dog Canis familiaris MDM2P2
Panda Ailuropoda melanoleuca MDM2P2
Cat Felis catus MDM2P1
Green monkey Chlorocebus sabaeus Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>MDM2P1
ATATGTTGTGAAAGAAGCAGTAGCAGTGAATTGACAGAGATGCATCAAATCTGATCTTAATATTGGTTTAAGTGAGCATTCAGGTTACTGGTGGGAGCAGGATTCAGTTTCAGATCAATTAATTGTAGAATTTGAATTTGAGTCTCCCAGAGTTTACAGCCTTAATGAACAACAACAAGAATTCTCAGATGAAGATGATGAGGTGTGTCCAGTTACTGTATATTAGACATGGGGATAGTGGTACAGATTCACTTGATGAAGGTCCTAAAATTTTCTTAGCTGACTTGAAAATGTACTTTATTAAATGAAATTGATCCTCCCCTTCTAGGCCATTTCAACAGATGTTGGTCCCTTTGTAAGAACTGACTTCCTGAAGATAAAGGGACAGATAGAGGGAAAATA
>NM_001266402.1
cggcaccgcggcTAGCTTGGCTGCTCGTGGGGCCTCTCCGGCCCTGTGTATCGGGAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCCCGACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCCCCGTCCCTCCCCGGATTAGTGCATTCGAGCGCCCAGTGCCCTGGCCCCGAGAGTGGAATGGTCCCCAAGGCCCAGGACGTCGTGCTTCCGCGGGCCCCGTGAAGGAAACTGGGGAGTCTCGAGGGACCCCCGACTCCAAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCTGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGTGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGAAACTTGGTAGTAGTCAATCAGCAGGAATCATCAGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTGCAAGAGCTTCAGGAAGAGAAACCTTCGTCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCGATTAGTGAGACAGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCGTCGAATCCGGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAGTTTAGTGTAGAATTTGAAGTTGAATCTCTCGACTCAGAAGATTATAGCCTTAGTGAAGAAGCACAAGAACTCTCAGATGAAGATGATGAGGTATATCGAGTTACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAATGCACTTCATGCAATGAAATGAATCCCCCTCTTCCATCACATTGCAACAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCTGAAGATAAAGGGAAAGATAAAGGGGAAATCTCTGAGAAAGCCAAACTGGAAAACTCAACACAAGCTGAAGAGGGCTTTGATGTTCCTGATTGTAAAAAAACTATAGTGAATGATTCCAAAGAGTCGTGTGTTGAGGAAAATGATGATAAAATCACACAAGCCTCACAATCACAAGAAAGTGAGGACTATTCTCAGCCATCAACTTCTAGTAGCATTATTTATAGCAGCCAAGAAGACGTGAAAGAGTTTGAAAGGGAAGAAACACAAGACAAAGAAGAAAGTGTGGAATCTAGTTTGCCCCTTAATGCCATTGAACCTTGTGTGATTTGTCAGGGTCGACCTAAAAATGGTTGCATTGTCCATGGCAAAACAGGACATCTTATGGCCTGCTTTACATGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGCCCAGTGTGTAGACAACCAATTCAAATGATTGTGCTAACTTATTTCCCCTAGTTGACCTGTCTGTAAGAGAATTATATATTTCTAACTAACCCTAAGAATTTAGACAACATGAAAATTATTTACATATATCAAAGTGAGAAAATGCTTCAGTCCACATAGATGTCTTCTCTTTAGTATAATTGACCTACTTTGGTAGCAGAATAGTGAATACTTACTATAATTTGCGTTGAATATGTAGCTCATCCTTTACCCCAACCCCTAATTTTAAATAATTTCTATTCTGTCTTAAATGAGAAGTGTCTTTTTTTTTTTTTAAATATATGTATATGGCATTTAAATGTAACTTATTAAtttttttttgagatggattctcgctgtgtcgcccaggctggagtgcag

Publications

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