Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name MDM2P2
Plot displaying the genomic locations of a retrocopy (in chr17) and its respective parental gene (in chr10). Each line represents a retrocopy.
Species Canis familiaris
Coordinates chr17:17061718-17062599  UCSC
Strand +
Parental Sequence NM_001003103.2
Parental seq. overlap 713 bp
Parental seq. overlap (%) 48%
Genomic Region Intergenic
Retrocopy Summary MDM2P2, located on chr17:17061718-17062599, is a retrocopy of the parental gene MDM2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name MDM2
Full Name MDM2 proto-oncogene
Also known as -
Coordinate chr10:11060051-11086867
Strand +
Gene summary N/A

Homology

Species Scientific Name Retrocopy
Crab-eating macaque Macaca fascicularis MDM2P1
Rhesus Macaca mulatta MDM2P1
Baboon Papio anubis MDM2P1
Golden snub-nosed monkey Rhinopithecus roxellana MDM2P2
Mouse lemur Microcebus murinus LOC105884627P1
Dolphin Tursiops truncatus MDM2P1
Panda Ailuropoda melanoleuca MDM2P2
Cat Felis catus MDM2P1
Egyptian rousette Rousettus aegyptiacus MDM2P1
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Horse Equus caballus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>MDM2P2
TCAGATGAATTACCTggtgaatgaaaaagaaagcacCAGAAATCTGatagtatttccttttctttgatgaAAGCTTCACTTTATGTATAATAAGGGAGATATATTGTGAAGAAGCAGTAGCAAAGAATCCAGAGACTCCAGCAAATCCAGACCTTGATGCTGGTGTAAGTGAACATTCGGATGGTGGGATCAAGATTCAGGTTTAGATTACTTTGCTGTAGAATTTGAAGTTGAGTCTTGATTCAGAAGATTATAGTCTTAGTGAAGAAGAATAACTCTCAGAGGAAGATGATGAAGTATATCAAGGCAAATCATGCAGGAGAGAATGATATAGATTCACTTGAAGAAGATTCTGAAACTTTCTCAGCAGACTACTGGAAGTataatttatgaaatgaaatgaatcctccccttccacctcacTGCAACAGATGGTGGGCAATTGGTGAGAACTGGCttcataaagagaaagagaaaatatctgtaaaagcCAACTAGAAAAGTCAACACAAGTAGAAGAGGGCTTTGATGTTCTGAttgtagacccacaaagaACTACAGTAGATGATTCTAAAAAGTCATATGGTGAAGAAAATGATGATCACACAAACCTCCCAGTTCTAAGCACTATTCTCAGACATCAACTTCTAATTGCATCACATAGCAGCCAAGAAGATGTCAAGGAGTTTGAGTGTTAAAAAAAcatgagacaaagaagaaaatatggaaccTAGTTTTGTCCTTAATGCCACTGATTCTCATGTGATTTGCCAAGGTTGACctaaaaataatcacattgtCCATTGCAATATAGGACATCTTATGGCATGTTTTACATGTGCAAAGAAGCT
>NM_001003103.2
AGGCAAATGTGCAATACCAACATGTCTGTGTCTACTGATGGTGCTGTAAGCACCTCACAGATTCCAGCTTCGGAGCAGGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTGTTGAAGTCTGTAGGTGCACAAAAAGACACTTATACTATGAAAGAGGTGATATTTTATCTTGGCCAGTATATTATGACTAAACGATTGTATGATGAGAAGCAACAGCATATTGTGTATTGTTCCAATGATCTTCTAGGAGATTTGTTTGGAGTGCCAAGCTTCTCTGTGAAAGAGCACAGgaaaatatatacaatgaTCTACAGAAACTTGGTAGTAGTCAATCAGCATGAACCATCAGATTCAGGCACATCTGTGAGTGAAAATAGCTGTCACCGTGAAGGTGGGAGTGATCAAAAGGACCCTGTGCAAGAGTTGCAGGAAGAGAAACCTTCATCTTCAGATTTGATTTCTAGACCATCTACCTCATCTAGAAGGAGAACAATTAGTGAGACAgAAGAACATGCAGATGATTTACCTGGTGAACGGCAGAGAAAGCGCCACAAATCTGATagtatttccctttcctttgatGAAAGCCTTGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAGTCAACAGGGACGCCATCAAATCcgGATCTTGATGCTGGTGTAAGTGAACATTCAGGTGATTGGTTGGATCAGGATTCAGTTTCAGATCAATTCAGTGTAGAATTTGAAGTTGAGTCTCTTGATTCAGAAGATTATAGCCTTAGTGAAGAAGGACAAGAACTCTCAGATGAAGATGATGAGGTGTATCGAGTAACTGTGTATCAGGCAGGGGAGAGTGATACAGATTCATTTGAAGAAGATCCTGAAATTTCCTTAGCTGACTATTGGAAGTGTACCTCATGCAATGAAATGaatcctcctcttccacctcattGCAATAGATGTTGGGCCCTTCGTGAGAATTGGCTTCCtgaagataaagggaaaatccCTGAGAAAGCCACACCAGAAAACTCAACACAAGTAGAAGAGGGCTTTGATGTCCCTGATTGTAAAAAAGCTGCAGCCAGTGATTCCAGAGAATCATGTGCTGAGGAAATTGATGATAAAATCACACAAGCCTCCCACTCCCAAGAAAGTGAGGACTATTCTCAGCCATCAACTTCTAACAGCATCATTTATAGCAGCCAAGAAGATGTCAAagaatttgagagagaagaaacacaaGACAAAGAAGAAATTGTGGAATCTAGTTTTCCCCTTAATGCCATTGAACCTTGTGTGATTTGCCAAGGTCGACCTAAAAACGGTTGCATTGTTCATGGCAAAACAGGACATCTTATGGCATGCTTCACGTGTGCAAAGAAGCTAAAGAAAAGGAATAAGCCCTGTCCAGTATGTAGACAACCAATTCAAATGATTGTGCTAACTTATTTCCCCTAATGGAC

Publications

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